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VEPMSATHLTLSTKLVYELGDPNSTLRATTARSGSAVLIYAGGEIDACNEDTWRHLVSEAAGVVATPGPF VVDVTGLEFMGCCAFAVLTDEAKRCRQRGIDLRLVSCEPIVGRIIDACGLSDILPIYPTVDSALSGADRW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3518 | - | - | 100% (140) | anti-anti-sigma factor |
| M. avium 104 | MAV_0435 | - | 5e-05 | 26.53% (98) | anti-anti-sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2671 | - | 7e-48 | 69.92% (133) | hypothetical protein Mb2671 |
| M. gilvum PYR-GCK | Mflv_4424 | - | 2e-06 | 29.52% (105) | anti-sigma-factor antagonist |
| M. tuberculosis H37Rv | Rv2638 | - | 7e-48 | 69.92% (133) | hypothetical protein Rv2638 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2512 | - | 1e-05 | 30.61% (98) | hypothetical protein MAB_2512 |
| M. marinum M | MMAR_2061 | - | 8e-40 | 59.69% (129) | hypothetical protein MMAR_2061 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2508 | - | 4e-06 | 29.91% (107) | PUTATIVE putative anti-sigma-factor antagonist |
| M. ulcerans Agy99 | MUL_3282 | - | 4e-39 | 58.91% (129) | hypothetical protein MUL_3282 |
| M. vanbaalenii PYR-1 | Mvan_1481 | - | 4e-07 | 28.85% (104) | anti-sigma-factor antagonist |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2671|M.bovis_AF2122/97 MGLITTEPRSSPHP-LSPRLVHELGDPHSTLRATTDGSGAALLIHAGGEI
Rv2638|M.tuberculosis_H37Rv MGLITTEPRSSPHP-LSPRLVHELGDPHSTLRATTDGSGAALLIHAGGEI
MAV_3518|M.avium_104 -----MEPMSATHLTLSTKLVYELGDPNSTLRATTARSGSAVLIYAGGEI
MMAR_2061|M.marinum_M MSVDIAEPFT-PHPMLSIRLVRELGDPHSTLRATTDFRSAAVLIHAGGEV
MUL_3282|M.ulcerans_Agy99 MSVDIAEPFT-PHPMLSIRLLRELGDPHSTLRAATDFRSTAVLIHAGGEV
Mflv_4424|M.gilvum_PYR-GCK -----------------------MAERVGLLEIGQEVHDVAVVVRAGGEV
Mvan_1481|M.vanbaalenii_PYR-1 -------------------MDVSGHGRSRGFSVSPDRQGAALVLRVTGDL
TH_2508|M.thermoresistible__bu --------MILPVPRPSPGGGEAVTCHAADFATR-WVNSATVVIRVDGEL
MAB_2512|M.abscessus_ATCC_1997 MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATGEI
:::: . *::
Mb2671|M.bovis_AF2122/97 DGRNEHLWRQLVTEAAAGVTAP--GPLIVDVTGLDFMGCCAFAALADEAQ
Rv2638|M.tuberculosis_H37Rv DGRNEHLWRQLVTEAAAGVTAP--GPLIVDVTGLDFMGCCAFAALADEAQ
MAV_3518|M.avium_104 DACNEDTWRHLVSEAAGVVATP--GPFVVDVTGLEFMGCCAFAVLTDEAK
MMAR_2061|M.marinum_M DAANEHTWRQLIAETAASAPSP--GLFIVDVSGLDFMGCCAFEVLAEQAG
MUL_3282|M.ulcerans_Agy99 DAANEHTWRQLIAETAASAPSP--GLFVVDVSGLDFMGCCAFEVLAEQAG
Mflv_4424|M.gilvum_PYR-GCK DSGTVETLAAALDSAVAAAAAHPTRTVVVDLDGITYFGSAGLNALLTCRE
Mvan_1481|M.vanbaalenii_PYR-1 DAMTAPTLVTHLDIALADAPPV----VVVDMTDVEFLSSAGISVLVETHR
TH_2508|M.thermoresistible__bu DAANSPQLVDYALRHAGRIKYL-----VADLTGVEFFGIAGFSAAHDING
MAB_2512|M.abscessus_ATCC_1997 DAVNANHLAEYATRYLDGHRTL-----VLDLQGLRFFGTDGLVALDRVRR
*. . : *: .: ::. .: .
Mb2671|M.bovis_AF2122/97 RCRCRGIDLRLVS-HQPIVARIAEAGGLSRVLPIYPTVDTALGKGTAGPA
Rv2638|M.tuberculosis_H37Rv RCRCRGIDLRLVS-HQPIVARIAEAGGLSRVLPIYPTVDTALGKGTAGPA
MAV_3518|M.avium_104 RCRQRGIDLRLVS-CEPIVGRIIDACGLSDILPIYPTVDSAL----SGAD
MMAR_2061|M.marinum_M RCRARGVELRIASAAHTRVTRIVAACGLSDALPVYRSVDAALA--LPAPS
MUL_3282|M.ulcerans_Agy99 RCRARGVELRIASAAHTRVTRIVAACGLSDALPVYRSVDAALA--LPAPS
Mflv_4424|M.gilvum_PYR-GCK EGEGRGVVVRLVA-TTAEVTRPIEVTRLARILRPYPSVGEAVAAPEDPPE
Mvan_1481|M.vanbaalenii_PYR-1 LAERADISLRVVA-DGPATSRPFRMMRLDEVIDLYPTLADAMGERQQGRP
TH_2508|M.thermoresistible__bu RCAHAKLTWTLVP--SPAVVRLLQICDPDGTLPLNTTVPDSVWDNGGSGG
MAB_2512|M.abscessus_ATCC_1997 HCKVQGIDWTVIP--GDAVTKLLTLSGDMAAYPVNDAIPDVWKKLAQ---
: : . . : ::
Mb2671|M.bovis_AF2122/97 RC-------
Rv2638|M.tuberculosis_H37Rv RC-------
MAV_3518|M.avium_104 RW-------
MMAR_2061|M.marinum_M D--------
MUL_3282|M.ulcerans_Agy99 D--------
Mflv_4424|M.gilvum_PYR-GCK DPR------
Mvan_1481|M.vanbaalenii_PYR-1 PT-------
TH_2508|M.thermoresistible__bu LFQLIPEAG
MAB_2512|M.abscessus_ATCC_1997 ---------