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M. tuberculosis H37Rv Rv1088 (PE9)

annotation: PE FAMILY PROTEIN
coordinates: 1214513 - 1214947
length: 144

MSYMIATPAALTAAATDIDGIGSAVSVANAAAVAATTGVLAAGGDEVLAAIARLFNANAEEYHALSAQVA
AFQTLFVRTLTGGCGVFRRRRGRQCVTAAEHRAAGAGRRQRRRRSGDGQWRLRQQRHFGCGGQPEFRQHS
EHRR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1088PE9-100% (144)PE FAMILY PROTEIN
M. tuberculosis H37RvRv0124PE_PGRS21e-2360.92% (87) PE-PGRS family protein
M. tuberculosis H37RvRv2396PE_PGRS412e-2259.77% (87) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1117PE92e-79100.00% (144) PE family protein
M. gilvum PYR-GCK-----
M. leprae Br4923MLBr_01183-5e-0832.05% (78) hypothetical protein MLBr_01183
M. abscessus ATCC 19977-----
M. marinum MMMAR_4224-1e-2256.32% (87) PE-PGRS family protein
M. avium 104MAV_1346-3e-1040.00% (80) PE family protein
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1145-3e-2251.92% (104) PE-PGRS family protein
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv1088|M.tuberculosis_H37Rv      MS-YMIATPAALTAAATDIDGIGSAVSVANAAAVAATTGVLAAGGDEVLA
Mb1117|M.bovis_AF2122/97         MS-YMIATPAALTAAATDIDGIGSAVSVANAAAVAATTGVLAAGGDEVLA
MMAR_4224|M.marinum_M            MS-FLVTAPEILAAAATDLDGIGAAIGAANAAAAAPTTAVLAAGADEISA
MUL_1145|M.ulcerans_Agy99        MS-YVVASPEYVAAAASDLAGIGSALSTANAAAAAPTIEVLAAGADEVSA
MLBr_01183|M.leprae_Br4923       MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MAV_1346|M.avium_104             MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSA
                                 *. :: : *  : *.*. : *:.::  . ****.  *  : ....*::  

Rv1088|M.tuberculosis_H37Rv      AIARLFNANAEEYHALSAQVAAFQTLFVRTLTGGCGVFRRRR--------
Mb1117|M.bovis_AF2122/97         AIARLFNANAEEYHALSAQVAAFQTLFVRTLTGGCGVFRRRR--------
MMAR_4224|M.marinum_M            AMASLFTAHAQAYQGLSVQVGAFHNQFVQALTGAGGAYAAAEAANVSPLQ
MUL_1145|M.ulcerans_Agy99        AIAAFFGAHAQAYQALSEQASAFHLQFVQAMTAGAGAYAGAEAVNASPLQ
MLBr_01183|M.leprae_Br4923       LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN-----
MAV_1346|M.avium_104             LQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRVNTS
                                   *  * . .  *:  : *  : :  ::: :    . :   .        

Rv1088|M.tuberculosis_H37Rv      ------------------GRQCVTAAEHRAAG------------------
Mb1117|M.bovis_AF2122/97         ------------------GRQCVTAAEHRAAG------------------
MMAR_4224|M.marinum_M            AAAQDMLTAIRAPAQALLGRPLIGNGADGAPGQAGGDGGLLYGNGGNGGT
MUL_1145|M.ulcerans_Agy99        AA----LDVLNAPAQALFGRPLIGDGAGGAPGQSGGDGGLLYGNGGNGGN
MLBr_01183|M.leprae_Br4923       -------------------------HDSL---------------------
MAV_1346|M.avium_104             AAALQGLAPNVIPNAAPAADPPPAGTTSLGTS------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      ---------AGRRQ-------------------RRRRSGDGQWRLRQQRH
Mb1117|M.bovis_AF2122/97         ---------AGRRQ-------------------RRRRSGDGQWRLRQQRH
MMAR_4224|M.marinum_M            STTAGVAGGAGGSAGLIGNGGAGGGGG---AGAVGGNGGAGGWLFGNGGA
MUL_1145|M.ulcerans_Agy99        GG-VGQAGGAGGAAGLIGNGGSGGIGGPGTTGLAGGAGGSGGWLFGNGGT
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             ---------IGWAQNVGAAASDFITLGEGQFAPVPGAAGIPNFNPGLTAA
                                                                                   

Rv1088|M.tuberculosis_H37Rv      FGCGGQ--PEFRQHSEHRR-------------------------------
Mb1117|M.bovis_AF2122/97         FGCGGQ--PEFRQHSEHRR-------------------------------
MMAR_4224|M.marinum_M            GGAGGA-TPGIGGGGGAGG-----------------------AGGIGGAA
MUL_1145|M.ulcerans_Agy99        GGRGGIGTTGIGGIGGTGGDAVGLFGHGGTGGTGGNGPDIFIAGGAGGSG
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             TTAGPP--APAAPAAAAGAPVLASMGRGPSIGGLSVPPSWAPGGVAPAAN
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            G----LFGNGGAGG-----------------VGGDGGLNYYG-----DGG
MUL_1145|M.ulcerans_Agy99        GTGGLLFGNGGAGGGAPWGGADGGAGGDARLIGNGGGGGYEGSLGVLSGG
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             ATPAQLVGAG-----------------------FTSAAPDTAPVTAVPGG
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            VAGAGGDGGRGGWLHGDGGDGGAGGDGGRGLPG-------------GDGG
MUL_1145|M.ulcerans_Agy99        TAGPGGDGGNAVGLIGNGGAGGAGAAGLSGVTGGIGGNGGNGAQLFGNGG
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             VPSMATAGRGGYGLGAPRYGVKPTVMPKPAI-------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            SGGAGG-------GTG-------LWGSGGAGGQG-----GTGGTGLNGNA
MUL_1145|M.ulcerans_Agy99        AGGAGGQSQLASGGTGGSGGMAALFGNGGAGGAAGVSLSGAPGTGGNGGS
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            P--FADGQHPVILD-GGHGGTGGNGGAAGN--------------------
MUL_1145|M.ulcerans_Agy99        AQFMGDGDSGGLGDSGGSAGAAGAGGLIGNPLDVVNAPTEALLGRPLIGD
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            ------------GGLLFGNGGNG--GLGGMGGGGGNGLPSTGVGGDGGDG
MUL_1145|M.ulcerans_Agy99        GADGAPGESGQDGGLLYGNGGNGGNGLSGQAGGAGGAAGLIGNGGNGGIG
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            G------NGGTAGNGGWLIGNGGTGGQG----------GAGFAG------
MUL_1145|M.ulcerans_Agy99        GPGTTGMSGGAGGAGGWLIGNGGHGGIGGLGIGIGDSGGAGGAGGAAIGL
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            -------GTGADNVSAGRPGGAGGTGGIG-------------------AG
MUL_1145|M.ulcerans_Agy99        FGNGGTGGTGGYNQAFGAVSGVGGAGGAGGQWYGNGGDGGTSWGGAAAGA
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            GGNAGLIGTGGSGGNG------GMGGHGGDSGYGDQTGGQGGNGGMGGAG
MUL_1145|M.ulcerans_Agy99        GGDAGLIDNGGDGDSAGVLRQNGIGGHGGAGGSLFGDGGDGGSAGFQSTA
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            GAAGNGGLLLGSGSRG------------------GDGGDGGN--------
MUL_1145|M.ulcerans_Agy99        GDGGNAGLVGNGGNGGWAIYNSFAGDDGSGGTAIGNGGDGGANIVSSGFI
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            ---GGEGRGGFSVPQHGVGGQGGT------------GGNGSDGGWLYGDG
MUL_1145|M.ulcerans_Agy99        LGAGGGGNGGNAVGLIGNGGAGGTGADGFSTALGSDGGNGGTGAWLLGNG
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      --------------------------------------------------
Mb1117|M.bovis_AF2122/97         --------------------------------------------------
MMAR_4224|M.marinum_M            GAGGAGG---------------------NGGFGGSGVQNGAG---GDAGS
MUL_1145|M.ulcerans_Agy99        GAGGSGGSTAGVHPAGDGGNSGMSALIGNGGAGGSAGVSPTGVFPSNGGS
MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Rv1088|M.tuberculosis_H37Rv      ----------------------------------------
Mb1117|M.bovis_AF2122/97         ----------------------------------------
MMAR_4224|M.marinum_M            GGDSRLIGDGGAAGAGGTGAPPGADGHSGADGLLSAALGA
MUL_1145|M.ulcerans_Agy99        GGNAQLIGDGGDGGRGDSGGTGGAGGTGGSLAGHDGSDGD
MLBr_01183|M.leprae_Br4923       ----------------------------------------
MAV_1346|M.avium_104             ----------------------------------------