For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LPCVGYGDRREFVDAVAVEAICENLNTSGQPDPDLVIRTSGEQRLSGHRGPTGGVSRRRLLRALRDYSTP HASIPYVPPPYRSDGIHASRLAVESVFDALAGRVEL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1087A | - | - | 100% (106) | hypothetical protein Rv1087A |
| M. tuberculosis H37Rv | Rv1086 | - | 7e-14 | 47.12% (104) | short (C15) chain Z-isoprenyl diphosphate synthase (Z-FPP |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1116A | - | 1e-58 | 100.00% (106) | hypothetical protein Mb1116A |
| M. gilvum PYR-GCK | Mflv_2055 | - | 2e-13 | 47.06% (102) | undecaprenyl diphosphate synthase |
| M. leprae Br4923 | MLBr_02467 | - | 3e-13 | 46.08% (102) | putative undecaprenyl pyrophosphate synthetase |
| M. abscessus ATCC 19977 | MAB_1209 | - | 5e-12 | 45.45% (99) | short-chain Z-isoprenyl diphosphate synthetase |
| M. marinum M | MMAR_4380 | uppS | 9e-14 | 47.06% (102) | short (C15) chain Z-isoprenyl diphosphate synthase, UppS |
| M. avium 104 | MAV_1211 | - | 7e-14 | 47.06% (102) | short-chain Z-isoprenyl diphosphate synthetase |
| M. smegmatis MC2 155 | MSMEG_5256 | uppS | 4e-12 | 51.35% (74) | undecaprenyl diphosphate synthase |
| M. thermoresistible (build 8) | TH_2165 | uppS | 5e-13 | 44.12% (102) | undecaprenyl diphosphate synthase |
| M. ulcerans Agy99 | MUL_0193 | uppS | 7e-14 | 47.06% (102) | short (C15) chain Z-isoprenyl diphosphate synthase, UppS |
| M. vanbaalenii PYR-1 | Mvan_4662 | - | 3e-13 | 47.06% (102) | undecaprenyl diphosphate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5256|M.smegmatis_MC2_155 ---------MDIIPPRLKEPAYRIYEMRLRHELVRSKAQLPRHIAVLCDG
TH_2165|M.thermoresistible__bu ---------VDIIPPRLKEPAYRLYEMRLRQELARSKSQLPRHIAVLCDG
MMAR_4380|M.marinum_M ---------MEIIPPRLKEPLYRLYELRLRQGLAATSSELPRHIAVLCDG
MUL_0193|M.ulcerans_Agy99 MRVTVVWILVEIIPPRLKEPLYRLYELRLRQGLAATSSELPRHIAVLCDG
MLBr_02467|M.leprae_Br4923 ---------MEIIPPRLKEPLYALYELRLRQGLTASESRLPRHIAVLCDG
MAV_1211|M.avium_104 -------MFVEIIPPRLKEPLYRIYEMRLRQELGAAKADLPRHIAVLCDG
MAB_1209|M.abscessus_ATCC_1997 ---------MEIIPPRLKEPLYKLYEMRLRQELVKASK--PRHIAVLCDG
Mflv_2055|M.gilvum_PYR-GCK ---------MDLIPRRLKEPMYRLYEMRLRQGLSVKRSELPRHIAVLCDG
Mvan_4662|M.vanbaalenii_PYR-1 -------MIVDLIPRRLKEPMYRLYELRLRQGLTASRSELPRHIAVLCDG
Rv1087A|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116A|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_5256|M.smegmatis_MC2_155 NRRWARDAGYDDVSIGYRKGAAKIAEMLRWCQAAGIEMATIYLLSTENLQ
TH_2165|M.thermoresistible__bu NRRWARDAGHDDVSYGYRKGAAKIAEMLRWCQDTGIELATIYLLSTENLQ
MMAR_4380|M.marinum_M NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MUL_0193|M.ulcerans_Agy99 NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MLBr_02467|M.leprae_Br4923 NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MAV_1211|M.avium_104 NRRWARDAGYDDVSYGYRMGAVKIAEMLRWCQAAGIEMTTVYLLSTENLQ
MAB_1209|M.abscessus_ATCC_1997 NRRWARSAGYTDVSHGYRMGARKISEMLGWCQDAGVEMATVYLLSAENLT
Mflv_2055|M.gilvum_PYR-GCK NRRWARETGHDDVAYGYRVGAGKIAEMLRWCQEAGIEMATVYLLSTENLQ
Mvan_4662|M.vanbaalenii_PYR-1 NRRWARESGHDDVSYGYRAGARKIAEMLRWCQEAGIEMATVYLLSTENLQ
Rv1087A|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116A|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_5256|M.smegmatis_MC2_155 RDPDELTALIEIITDVVEEICAPYNKWSVRTVGDLELLGDEPARRLREAV
TH_2165|M.thermoresistible__bu RDPDELTALIEIITEVVEEICAPANKWSVRTVGDLALLGEEPARRLREAV
MMAR_4380|M.marinum_M RDADELAALIEIITDVVEEICAPANRWSVRTVGDLELLGDEPARRLREAV
MUL_0193|M.ulcerans_Agy99 RDADELAALIEIITDVVEEICAPANRWSVRTVGDLELLGDEPARRLREAV
MLBr_02467|M.leprae_Br4923 RDPDELAALIEIITDVVEEICAPANRWSVRTVGDLELLGEEPACRLRGAV
MAV_1211|M.avium_104 RDPDELAGLIEIITDVVEEICAPANRWSVRTVGDLELLGEEPARRLRGAV
MAB_1209|M.abscessus_ATCC_1997 RDPDQLTELLEIITDVVEELCAPQNKWSVRSVGDLDLLPDEVAERMRQAV
Mflv_2055|M.gilvum_PYR-GCK REPEELSCLIEIITEVVEEICAPANQWSVRTVGDLELIGEDQARRLRDAV
Mvan_4662|M.vanbaalenii_PYR-1 RDTEELSALIEIITEVVEEICAPANQWSVRTVGDLELIGEESARRLRDAV
Rv1087A|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116A|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_5256|M.smegmatis_MC2_155 ESTTTKG--ANFHVNVAVAYGGRQEIVDAVRSLLSKELANGATAEQLIEA
TH_2165|M.thermoresistible__bu DRTETVADAAAFHVNVAVGYGGRQEIVDAVRALLSKELANGASPEQLIQS
MMAR_4380|M.marinum_M ESTPATA---QFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELIDA
MUL_0193|M.ulcerans_Agy99 ESTPATA---QFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELIDA
MLBr_02467|M.leprae_Br4923 ESTPGVA---PFHVNVAVGYGGRREIVGAVRALLGKELANGATAEELVEA
MAV_1211|M.avium_104 ESTPVEA---SFHVNVAVGYGGRREIVDAVRSLLSKELANGATAEELIDA
MAB_1209|M.abscessus_ATCC_1997 KSAPSDA---GFHVNVAVGYGGRQEITDAVRTLLNKELANGASAEQLVQA
Mflv_2055|M.gilvum_PYR-GCK SSTDGNG--GAFHVNVAVGYGGRQEIVDAVRALLSKELANGATGDQLVEA
Mvan_4662|M.vanbaalenii_PYR-1 SSTDGNG--GTFHVNVAVGYGGRQEIVDAVRALLSKELANGLTGEQLIES
Rv1087A|M.tuberculosis_H37Rv --------------MPCVGYGDRREFVDAV--------------------
Mb1116A|M.bovis_AF2122/97 --------------MPCVGYGDRREFVDAV--------------------
.*.**.*:*:..**
MSMEG_5256|M.smegmatis_MC2_155 VTVDGISENLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
TH_2165|M.thermoresistible__bu VTIDAISENLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
MMAR_4380|M.marinum_M VSVEGISENLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
MUL_0193|M.ulcerans_Agy99 VSVEGISENLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
MLBr_02467|M.leprae_Br4923 VTVEGIARNLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
MAV_1211|M.avium_104 VTVDAISENLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
MAB_1209|M.abscessus_ATCC_1997 VTVDAISENLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
Mflv_2055|M.gilvum_PYR-GCK VTAEAISENLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
Mvan_4662|M.vanbaalenii_PYR-1 VTAEAISENLYTSGQPDPDLVIRTSGEQRLSG------------FLLWQS
Rv1087A|M.tuberculosis_H37Rv -AVEAICENLNTSGQPDPDLVIRTSGEQRLSGHRGPTGGVSRRRLLRALR
Mb1116A|M.bovis_AF2122/97 -AVEAICENLNTSGQPDPDLVIRTSGEQRLSGHRGPTGGVSRRRLLRALR
: :.*..** ********************* :*
MSMEG_5256|M.smegmatis_MC2_155 AYSEMWFTEAYWPAFRRVDFLRALR-----DYTARHRRFGK
TH_2165|M.thermoresistible__bu AYSEMWFTEAHWPAFRRVDFLRALR-----DYTRRHRRFGM
MMAR_4380|M.marinum_M AYSEMWFTEAHWPAFRRVDFLRALR-----DYSMRHRRYGK
MUL_0193|M.ulcerans_Agy99 AYSEMWFTEAHWPAFRRVDFLRALR-----DYSMRHRRYGK
MLBr_02467|M.leprae_Br4923 AYSEMWFTETHWPAFRRVDFLRALR-----DYSMRHRRYGK
MAV_1211|M.avium_104 AYSEMWFTEAHWPAFRRVDFLRALR-----DYSQRHRRYGK
MAB_1209|M.abscessus_ATCC_1997 AYSEMWFTDAYWPEFRRVDFLRALR-----DYAARNRRFGQ
Mflv_2055|M.gilvum_PYR-GCK AYSEMWFTEAYWPEFRRVDFLRALR-----DYSARHRRYGR
Mvan_4662|M.vanbaalenii_PYR-1 AYSEMWFTEAYWPEFRRVDFLRALR-----DYSARHRRYGR
Rv1087A|M.tuberculosis_H37Rv DYSTPHASIPYVPPPYRSDGIHASRLAVESVFDALAGRVEL
Mb1116A|M.bovis_AF2122/97 DYSTPHASIPYVPPPYRSDGIHASRLAVESVFDALAGRVEL
** : .: * * * ::* * : *