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VSYVSVLPATLATAATEVARIGSALSLASAVAAAQTSAVQAAAADEVSAAIAALFSAHGRDFQALSARAA AFHHEFVQALAAGAGSYAVAEIAAASPLQSLIDVFNAPIQAATGRPLIGNGANGQPGTGAPGGPAGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0832 | PE_PGRS12 | - | 100% (137) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1818c | PE_PGRS33 | 2e-42 | 61.76% (136) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv2741 | PE_PGRS47 | 1e-41 | 61.03% (136) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0855 | PE_PGRS12 | 1e-70 | 100.00% (137) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_0326 | - | 7e-05 | 30.77% (91) | PE domain-containing protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-11 | 32.97% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0664 | - | 2e-08 | 37.63% (93) | PE family protein |
| M. marinum M | MMAR_4399 | - | 4e-43 | 62.50% (136) | PE-PGRS family protein |
| M. avium 104 | MAV_2915 | - | 5e-15 | 44.68% (94) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0618 | - | 3e-05 | 32.97% (91) | PE family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0212 | - | 3e-40 | 59.56% (136) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_0414 | - | 3e-05 | 32.97% (91) | PE domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0326|M.gilvum_PYR-GCK --MTLRVVPEGLTAASAAVEALTARMAAAHAAAAPLVTAVLPPAADAVSL
Mvan_0414|M.vanbaalenii_PYR-1 --MTLRVVPEGLTAAGAAVEALTARMAAAHAAAAPVVTAVLPPAADVVSL
MSMEG_0618|M.smegmatis_MC2_155 --MTLRVVPEGLTAASSAVEALTARLAAAHAAAAPMISTVLPPAADAVSL
MAB_0664|M.abscessus_ATCC_1997 --MSLNVVPEGLTAASAAVEALTARLAAVNAAAAPVIGAVMPPAADPVSM
Rv0832|M.tuberculosis_H37Rv -MSYVSVLPATLATAATEVARIGSALSLASAVAAAQTSAVQAAAADEVSA
Mb0855|M.bovis_AF2122/97 -MSYVSVLPATLATAATEVARIGSALSLASAVAAAQTSAVQAAAADEVSA
MMAR_4399|M.marinum_M -MSYVIAVPDLVAGAASELAGVGSTLSTATTAAAAQTTGVLAAAGDEVSA
MUL_0212|M.ulcerans_Agy99 -MSFVNVTPEAVAAAASDLTGIGSVLGEANAVAARATTTVLAAGGDEVSA
MAV_2915|M.avium_104 -MMYVTAQPEAMNAAADRLQQIGTALAAQTGANSAPMTGVVPAAADPVSL
MLBr_01183|M.leprae_Br4923 MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
: . * : *. : : : . : : ....* **
Mflv_0326|M.gilvum_PYR-GCK QTATGLSANGVEHQSIAARGVEELGRSGVGVGDSAASYVSGDAMAATSYL
Mvan_0414|M.vanbaalenii_PYR-1 QAATGFSARAAEHQSVAAQGVEELGRSGIAVGESAASYAGGDAMAASSYL
MSMEG_0618|M.smegmatis_MC2_155 QTAAGFSANGAQQSAVAAQGVEELGRSGVGVGESGVSYATGDAQAAASYL
MAB_0664|M.abscessus_ATCC_1997 QSAALFSAHGLERTGAGARAAYELGRSGVGATEAAASYTVGDIQAAATYL
Rv0832|M.tuberculosis_H37Rv AIAALFSAHGRDFQALSARAAAFHHEFVQALAAGAGSYAVAEIAAASPLQ
Mb0855|M.bovis_AF2122/97 AIAALFSAHGRDFQALSARAAAFHHEFVQALAAGAGSYAVAEIAAASPLQ
MMAR_4399|M.marinum_M AIAAVFSAHGQSYQTLSAQAETFHAQFVQALSAGASAYTQAEAASASPLA
MUL_0212|M.ulcerans_Agy99 AIAALFSFHGQSYQTLGAQAEAFHAQFAQLMANGAGTYASAEAANAAPFQ
MAV_2915|M.avium_104 LAAARFAQHGQAFQAVSAEAAAVHEMFVTTLQTSAGSYAGTEAANAAAAR
MLBr_01183|M.leprae_Br4923 LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL-
* :: .. .:.. .. :*. : .
Mflv_0326|M.gilvum_PYR-GCK IARG----------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 IARG----------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 TARGL---------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 PGIA----------------------------------------------
Rv0832|M.tuberculosis_H37Rv SLIDVFNAPIQAATGRPLIGNGANGQPGTGAPGGP---------AGG---
Mb0855|M.bovis_AF2122/97 SLIDVFNAPIQAATGRPLIGNGANGQPGTGAPGGP---------AGG---
MMAR_4399|M.marinum_M GLLAAINAPVQSLTGRPLIGNGANGTPGTGADGAPGGWLLGDGGAGGSGA
MUL_0212|M.ulcerans_Agy99 GLLGAVNAPVQTLTGRPLIGNGANGAPGTGANGGAGGWLIGNGGAGGSGA
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M PGLNGGAGGAAGLLGSGGAGGAGGSSTSTNGGAGGAGGAGGWLSGNAGVG
MUL_0212|M.ulcerans_Agy99 PGLNGGAGGAAGLIGTGGAGGAGGSSSTVNGGLGGTGGAGGWLLGNGGAG
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M GAGGASTVANG----GAGGAGGAGGLLGGGGLGGAGGASTSATASGGAGG
MUL_0212|M.ulcerans_Agy99 GAGGASAIPLGPDLIGKGGAGGPGGLFGAGGLGGAGGFGGSG---GGAGG
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M QGGAAGLLSGFVGADGGHGGAGGHGAAGGDGGAGGDGGPLAGAGGSGGTG
MUL_0212|M.ulcerans_Agy99 QGGAGGLLSGLVGAGGGHGGTGGY--------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M GSGNAGGGAGGAGGNAGLLFGDGGVGGTGGTSGQGVGGIGGDGGSAGLLF
MUL_0212|M.ulcerans_Agy99 -----GGGAGGAG----------------ATGGGNTGGIGGDGGSAGMLF
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M SNGGAGGAGGAGTALISGNGGAGGNGGNGGWLFSNGGVGGAGGAGAPAM-
MUL_0212|M.ulcerans_Agy99 SNSGAGGAGGAS---ELADGGAGGAGGNGGWLLSNGGVGGAGGAGADAVG
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M PSLGISAGSGGVGGAGGTGGLLLGNGGAGGAGGTSGNGGGTGGAGGAAGS
MUL_0212|M.ulcerans_Agy99 PPFGIPAGSGSGGGAGGAGGVFFGNGGAGGAGGTGGDGGGTGGAGGAAGN
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M GVLIGNGGNGGIGGAGPTPGGNGIGGTSGLLLGLDGFNAPTSTSPIHTLQ
MUL_0212|M.ulcerans_Agy99 GVLIGNGGNGGIG-------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M QQALNAINAPIQAATGRPLIGNGTPGDAGSGTDGTPGGWLLGDGGAGGSG
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M GTGLDGGDGGAAGLMGTGGTGGAGGWGGTDEITGGTGGAGGTGGGGGWLS
MUL_0212|M.ulcerans_Agy99 ---------GAAGLWGTGGTGGSG----------GSGGTGATGG------
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M GSGGIGGGGGAGGYGGAIIPGNGGAGGSAGAGGAGGLFGGGGTGGAGGTG
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M GPAGLGVFVGVPTFGDGGGGGAGGAGGAGGLLSGLVGAGGGDGGAGGQGG
MUL_0212|M.ulcerans_Agy99 -------FSGLLASGDGGAGGAGGAGGAGGLLDGLVGAGGGDGGAGG---
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M IGFGGSGGSGGGGGVGGNAGLLGGPGGAGGSGGAAGPALFGIGVDGTAGV
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M GGAGGNAGLLFGSGGAGGDGGFGPGAGGTGGRGGNAGLLFSSAGAGGFGG
MUL_0212|M.ulcerans_Agy99 -----NAGTLFGSGGVGGDGGSGHGNGGDGGGGGNAGLLFSDAGGGGFGG
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M YGTTGGG-TGGAGGDAGWLGCGGAGGAGGITIGGTGGTGGAGGTGGQLLG
MUL_0212|M.ulcerans_Agy99 FGLAGGGGTGGSGGDAGWLGSGGAGGAGGISVNGDAGAGGAGGTSGQLLG
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0832|M.tuberculosis_H37Rv --------------------------------------------------
Mb0855|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4399|M.marinum_M AGGAGGAGGQTDPLGGSTGGSGGVGGNAVLIGTGGNGGNGGAGTAKGTPG
MUL_0212|M.ulcerans_Agy99 DGGAGGAGGEAELAAGGAGGSGGVGGDAVLIGAGGNGGNGGPGTAKGDPG
MAV_2915|M.avium_104 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK -----------------
Mvan_0414|M.vanbaalenii_PYR-1 -----------------
MSMEG_0618|M.smegmatis_MC2_155 -----------------
MAB_0664|M.abscessus_ATCC_1997 -----------------
Rv0832|M.tuberculosis_H37Rv -----------------
Mb0855|M.bovis_AF2122/97 -----------------
MMAR_4399|M.marinum_M TGGTGGLIGVDGLSGAS
MUL_0212|M.ulcerans_Agy99 SGGAGGLLGVDGLNGLS
MAV_2915|M.avium_104 -----------------
MLBr_01183|M.leprae_Br4923 -----------------