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STHNDSAPTSRRRHIVRLVVFAGFLVGMFYLVAATDVIDVAAVRGAVSATGPAAPLTYVVVSAVLGALFV PGPILAASSGLLFGPLVGVFVTLGATVGTAVVASLVGRRAGRASARALLGGERADRTDALIERCGLWAVV GQRFVPGISDAFASYAFGTFGVPLWQMAVGAFIGSAPRAFAYTALGAAIGDRSPLLASCAIAVWCVTAII GAFAARHGYRQWRAHARGDGADGGVEDPDREVGAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0625c | - | - | 100% (246) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv2306B | - | 2e-36 | 77.17% (92) | hypothetical protein Rv2306B |
| M. tuberculosis H37Rv | Rv2306A | - | 2e-29 | 53.24% (139) | hypothetical protein Rv2306A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0641c | - | 1e-138 | 100.00% (246) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_5151 | - | 2e-80 | 65.33% (225) | hypothetical protein Mflv_5151 |
| M. leprae Br4923 | MLBr_00287 | - | 6e-05 | 24.74% (194) | hypothetical protein MLBr_00287 |
| M. abscessus ATCC 19977 | MAB_2713 | - | 5e-11 | 27.59% (174) | hypothetical protein MAB_2713 |
| M. marinum M | MMAR_3541 | - | 1e-88 | 71.81% (227) | hypothetical protein MMAR_3541 |
| M. avium 104 | MAV_4545 | - | 2e-95 | 78.48% (223) | hypothetical protein MAV_4545 |
| M. smegmatis MC2 155 | MSMEG_2840 | - | 2e-92 | 74.11% (224) | hypothetical protein MSMEG_2840 |
| M. thermoresistible (build 8) | TH_2317 | - | 2e-93 | 76.58% (222) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1504 | - | 2e-17 | 29.95% (207) | hypothetical protein MUL_1504 |
| M. vanbaalenii PYR-1 | Mvan_1181 | - | 4e-83 | 67.13% (216) | hypothetical protein Mvan_1181 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5151|M.gilvum_PYR-GCK ---------------MTDPTDAPETSKRRALVRLALVVAVLAVLFYLTAI
Mvan_1181|M.vanbaalenii_PYR-1 -------------MRMEDTEGTPETSRRRHITRLALFGAVLAVLYYLTAV
Rv0625c|M.tuberculosis_H37Rv -------------MSTHND-SAPTS-RRRHIVRLVVFAGFLVGMFYLVAA
Mb0641c|M.bovis_AF2122/97 -------------MSTHND-SAPTS-RRRHIVRLVVFAGFLVGMFYLVAA
MAV_4545|M.avium_104 -------------MDNQEAPDAPAS-RRAHILRLAVFAGFLAVVFYLVAV
TH_2317|M.thermoresistible__bu ----------------MTEPSPPAS-RWPHILRLAAFAGFLFTLFYLVAV
MMAR_3541|M.marinum_M ------------MTDTATDPAPPSASRGRHLVRLALFAGFLLGMFYLVAV
MSMEG_2840|M.smegmatis_MC2_155 ------------MTDTD---DPPATGRTRHIIRLALFAAFLLGLFYLVAV
MAB_2713|M.abscessus_ATCC_1997 ------------MGFRQIGRTAVATLRRLPRRQLLWTGAALLIVIAAVRF
MUL_1504|M.ulcerans_Agy99 MIVTASVLCKTTDTVRGIALALRTAARQMSRLRKVSTVAGITLLVAVALL
MLBr_00287|M.leprae_Br4923 --------------------------MNTAIVALPPTLDPMFWIGPEGFF
: :
Mflv_5151|M.gilvum_PYR-GCK ARVIDVEAVRDLIESTGPLAPLTYVGVSAVLGALLVPGPLLAAGSGFLFG
Mvan_1181|M.vanbaalenii_PYR-1 ERVIDVAQVRGLIESTGPAAPLTYVAVSAVLGALLVPGPLLAAGSGFLFG
Rv0625c|M.tuberculosis_H37Rv TDVIDVAAVRGAVSATGPAAPLTYVVVSAVLGALFVPGPILAASSGLLFG
Mb0641c|M.bovis_AF2122/97 TDVIDVAAVRGAVSATGPAAPLTYVVVSAVLGALFVPGPILAASSGLLFG
MAV_4545|M.avium_104 ARVIDVGEIRAVVSATGPAAPLTYVVASALAGALFVPGSILAAGSGLLFG
TH_2317|M.thermoresistible__bu VRVIDVDGVRGAIAAAGPVAPLVYVVVSAVLGAVFVPGPILAAGSGLLFG
MMAR_3541|M.marinum_M ARVIDIAGIRSAITATGPLAPLAYVVMSTVLGAVFVPGPILAAGSGVLFG
MSMEG_2840|M.smegmatis_MC2_155 ARVVEIGDIRGAVSATGPIAPLVYVVVSACLGALFVPGPLLAGTSGFLFG
MAB_2713|M.abscessus_ATCC_1997 VPLPTALQMRDWARDLGPWFPLAFLGAHTIVTVLPFPRTAFTLAAGLLFG
MUL_1504|M.ulcerans_Agy99 VPLPTAVQMRDWASSVGPWLPLVFLLVHIVVTVPPFPRTAFTVAGGLLFG
MLBr_00287|M.leprae_Br4923 AAAMLPATLVIIFVETGLLFPLLPGESLLFTGGLLATKGTIDI---WVLS
: * ** . : ::.
Mflv_5151|M.gilvum_PYR-GCK PVVGTVVTLGATVVNALISAYLGRRAGRQSARTLLGASRAEQVDRLIERG
Mvan_1181|M.vanbaalenii_PYR-1 PLVGTFVTLGATMGSAVISAFAGRRAGRDSARGLLGADRAERIDGLIQRG
Rv0625c|M.tuberculosis_H37Rv PLVGVFVTLGATVGTAVVASLVGRRAGRASARALLGGERADRTDALIERC
Mb0641c|M.bovis_AF2122/97 PLVGVFVTLGATVGTAVVASLVGRRAGRASARALLGGERADRTDALIERC
MAV_4545|M.avium_104 PLLGVFVTLGATVGTATAASFVGRRAGRDSARALLGPARADRVDALIGRG
TH_2317|M.thermoresistible__bu PLLGTFVTLGATVGTATVSCLLGRRAGRSSARALLGTDRADRLDALIDRR
MMAR_3541|M.marinum_M PILGTFVTLGATVGTAVVASLLGRRAGRDSARVLLGTDRANRLDARIERQ
MSMEG_2840|M.smegmatis_MC2_155 PVLGTFVTLGATVGTATVASLIGRRAGRESARGVLGAERADRLDRQIERG
MAB_2713|M.abscessus_ATCC_1997 TQLGVLLAVVASTASAVLALWAVRALGWKLS-ALHHRPAVKSVDDQLRRR
MUL_1504|M.ulcerans_Agy99 PVLGIVIAVTASTASAVIALLLVRAAGWRLN-RLVPHGAVDRLDERLRER
MLBr_00287|M.leprae_Br4923 PSVAVVAVLGDQIG-YLIGRRIGPALFKKENSRFFKQHYVTESHAFFEKH
. :. . .: . . . . : .
Mflv_5151|M.gilvum_PYR-GCK GLWAVVGQRFVPGISDSLASYAFGAFGVPLWQMAAGAFIGSMPRAFVYTV
Mvan_1181|M.vanbaalenii_PYR-1 GLWAVVGQRWIPGINDALASYTFGAFGVPLWQMAAGALIGSAPKAFVYTA
Rv0625c|M.tuberculosis_H37Rv GLWAVVGQRFVPGISDAFASYAFGTFGVPLWQMAVGAFIGSAPRAFAYTA
Mb0641c|M.bovis_AF2122/97 GLWAVVGQRFVPGISDAFASYAFGTFGVPLWQMAVGAFIGSAPRAFAYTA
MAV_4545|M.avium_104 GLWAVVGQRFVPGISDALASYAFGAFGVPLWQMAVGAFIGSAPRAFAYTA
TH_2317|M.thermoresistible__bu GLWAVVGQRFIPGVSDAMASYAFGAFGVPLWQMAVGAFIGSAPRAFVYTA
MMAR_3541|M.marinum_M GLWAVVGQRFIPGISDALASYTFGAFGVPLWQMILGSLIGSAPRAFVYTA
MSMEG_2840|M.smegmatis_MC2_155 GLWAVVGQRFVPGISDALASYAFGAFGVPLWQMVVGSFIGSAPRAFVYTA
MAB_2713|M.abscessus_ATCC_1997 GWIAVMSMRLIPAVPFSVLNYAAGASAVRALPYTLATFVGLLPGTLAVVV
MUL_1504|M.ulcerans_Agy99 GWLAILSLRLIPAVPFAALNYGAGASAVRVVPYTLSTLAGLLPGTVAVVI
MLBr_00287|M.leprae_Br4923 GRWTIILARFLP-FMRTFTPVIAGLSYMSYPLYLGFDIVGGILWGGGVTV
* ::: * :* . : * : : * .
Mflv_5151|M.gilvum_PYR-GCK VGSSVGEF---SAPLAFAAAAVWCVTAVIGAFAAHRGWRRWRARQ-----
Mvan_1181|M.vanbaalenii_PYR-1 VGSTLGEF---SAPLLAAAVVVWCVTAVVGAFAAHRGWRAWRSRE-----
Rv0625c|M.tuberculosis_H37Rv LGAAIGDR---SPLLASCAIAVWCVTAIIGAFAARHGYRQWRAHARGDGA
Mb0641c|M.bovis_AF2122/97 LGAAIGDR---SPLLASCAIAVWCVTAIIGAFAARHGYRQWRAHARGDGA
MAV_4545|M.avium_104 LGASIGNR---SSLLAYAAVAVWCVSAIVGAFAAHRGYRQWRGRPKDE--
TH_2317|M.thermoresistible__bu LGASIGDL---SAPLAYTAIAVWCVIAIVGAFAARQGFRSWQATARPRD-
MMAR_3541|M.marinum_M LGATIMNL---SSWLAYAAIAVWCVTAIVGAVTARREYRKWRERASDPAP
MSMEG_2840|M.smegmatis_MC2_155 LGASIGDL---SAPLAYTAIAVWCVTAIIGAFAAHRGYRSWRGRHQDPAS
MAB_2713|M.abscessus_ATCC_1997 LGDALTGH---ISPTLFAVSLATSAIGVLGILYEIRRYKRTHTEIP----
MUL_1504|M.ulcerans_Agy99 LGSALAGD---GSPLLVLVSVCTAALGMSGLVFEVRQYRRHHRHQAPSDH
MLBr_00287|M.leprae_Br4923 AGYFLGNVPFVRQNLEKIILGILFVSLLPALIAAWHGYRSQSRTAKSELA
* : . : . . : ::
Mflv_5151|M.gilvum_PYR-GCK ---------------
Mvan_1181|M.vanbaalenii_PYR-1 ---------------
Rv0625c|M.tuberculosis_H37Rv DGGVEDPDREVGAR-
Mb0641c|M.bovis_AF2122/97 DGGVEDPDREVGAR-
MAV_4545|M.avium_104 ------------AR-
TH_2317|M.thermoresistible__bu ------------VRP
MMAR_3541|M.marinum_M AESA-----------
MSMEG_2840|M.smegmatis_MC2_155 ---------------
MAB_2713|M.abscessus_ATCC_1997 DPESSGAPERVGR--
MUL_1504|M.ulcerans_Agy99 GPVLEPACEPLGV--
MLBr_00287|M.leprae_Br4923 LPD------------