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M. tuberculosis H37Rv Rv0577 (TB27.3)

annotation: hypothetical protein Rv0577
coordinates: 671166 - 671951
length: 261

MPKRSEYRQGTPNWVDLQTTDQSAAKKFYTSLFGWGYDDNPVPGGGGVYSMATLNGEAVAAIAPMPPGAP
EGMPPIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAVGLWQANRHIGATLVNE
TGTLIWNELLTDKPDLALAFYEAVVGLTHSSMEIAAGQNYRVLKAGDAEVGGCMEPPMPGVPNHWHVYFA
VDDADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0577TB27.3-100% (261)hypothetical protein Rv0577
M. tuberculosis H37RvRv0911-5e-3331.27% (259) hypothetical protein Rv0911

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0592TB27.31e-155100.00% (261) hypothetical protein Mb0592
M. gilvum PYR-GCKMflv_4018-4e-3733.85% (257) glyoxalase/bleomycin resistance protein/dioxygenase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0976-4e-4338.37% (258) putative glyoxalase/bleomycin resistance protein
M. marinum MMMAR_3576-3e-4338.76% (258) hypothetical protein MMAR_3576
M. avium 104-----
M. smegmatis MC2 155MSMEG_5616-1e-3232.42% (256) glyoxalase/bleomycin resistance protein/dioxygenase
M. thermoresistible (build 8)TH_0683-3e-2333.02% (212) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0158-1e-3131.91% (257) hypothetical protein MUL_0158
M. vanbaalenii PYR-1Mvan_4951-2e-3233.59% (256) glyoxalase/bleomycin resistance protein/dioxygenase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5616|M.smegmatis_MC2_155      ------------------------MPIRSTAPLGAPSWIDLTTSDVERAK
Mvan_4951|M.vanbaalenii_PYR-1       MSFSRRGGLHGDRSPPLRRPEETAMPVATTAPLGAPIWIDLATSDLDRAQ
MUL_0158|M.ulcerans_Agy99           ------------------------MPIRNAAPLGAPCWIDLTTSDIDRAQ
TH_0683|M.thermoresistible__bu      ------------------------VPLRHGAPLGAPIWIDLGTSDLDRAL
MAB_0976|M.abscessus_ATCC_1997      ------------------------MPTRDETPLGAPAWIDLASSDLEKSK
Mflv_4018|M.gilvum_PYR-GCK          -------------------------MSDYAAPVGAPIWLDLMSTDPARAA
Rv0577|M.tuberculosis_H37Rv         ------------------------MPKRSEYRQGTPNWVDLQTTDQSAAK
Mb0592|M.bovis_AF2122/97            ------------------------MPKRSEYRQGTPNWVDLQTTDQSAAK
MMAR_3576|M.marinum_M               ------------------------MGARTGYADGTFSWVDLATTEPEAAT
                                                                     *:  *:** :::   : 

MSMEG_5616|M.smegmatis_MC2_155      AFYGAVFGWTFETG-GPEYGG---YVTAHLEGHVVAGLMQNDPQW--NTP
Mvan_4951|M.vanbaalenii_PYR-1       QFYGAVFGWTFESA-GPEYGG---YVTAFRDDHPVAGLMVNDPQW--NAP
MUL_0158|M.ulcerans_Agy99           DFYGTVFGWTFESA-GPEYGG---YVNAARNGHPVAGLMANNPEW--QAP
TH_0683|M.thermoresistible__bu      QFYGAVFGWTFESA-GPDYGG---YVNAFSQGRPVAGLMRNDPQW--NAP
MAB_0976|M.abscessus_ATCC_1997      AFYSALFGWTLQEA-GPEYGG---YINAYKDGKAVAGMITNNPEW--NAP
Mflv_4018|M.gilvum_PYR-GCK          EFYHAVFGWDVEAPPQAEFGG---YQNFTVNGRRVAGLLPHMG----GVP
Rv0577|M.tuberculosis_H37Rv         KFYTSLFGWGYDDN--PVPGGGGVYSMATLNGEAVAAIAPMPPGAPEGMP
Mb0592|M.bovis_AF2122/97            KFYTSLFGWGYDDN--PVPGGGGVYSMATLNGEAVAAIAPMPPGAPEGMP
MMAR_3576|M.marinum_M               LFYGQLFGWTPEER--RTADG-RVYTVLCRDRQEVAGLYALPVADPAGDQ
                                     **  :***  :       .*   *     : . **.:            

MSMEG_5616|M.smegmatis_MC2_155      DVWTTYLHTADAQATVAAAAAAGGSNCGGVMDVPEKGRMAMMSDAAGGFF
Mvan_4951|M.vanbaalenii_PYR-1       DAWTVYLHTADIEATVAKATAAGGTSCVAPMEIPAKGWMGMLTDPTGAFL
MUL_0158|M.ulcerans_Agy99           DNWTTYFHTADITAAAAAVTAAGGSRCVDPMEIPAKGFMCMATDPAGAFF
TH_0683|M.thermoresistible__bu      DGWTTYLHTADIHATLAAATAAGGTSCMAPMEVKDKGWMAMLSDPTGGVF
MAB_0976|M.abscessus_ATCC_1997      DAWTTYFATEDIDATLQKAVTHGGTNCLPPMEVPQLGYMALFADPAGAMV
Mflv_4018|M.gilvum_PYR-GCK          NVWSVYLHTADAAETVRAVEAAGGSVMVPPMPVGDMGSMMVATDPAGAVI
Rv0577|M.tuberculosis_H37Rv         PIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAV
Mb0592|M.bovis_AF2122/97            PIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAV
MMAR_3576|M.marinum_M               TRWNSHISVADVDAAAARARALGGVILAGPLDLGDRGKMVVVRDPHGSVI
                                      *. :: . *   .   . . **      : :   * * .  *. *. .

MSMEG_5616|M.smegmatis_MC2_155      GLWQPAGHDGFQVFNEPGAPLYHQLTTGDYAKALQFYRDVFGWTVNTV--
Mvan_4951|M.vanbaalenii_PYR-1       GLWQPTGHRGYGIVGEHGAPVYHQLTTRGYGAALDFYRTVFGWTTETV--
MUL_0158|M.ulcerans_Agy99           GLWQPLGHRGFEIIGEAGAAVWHQLTTRDYHPAIGFYRRLFGWQTEQV--
TH_0683|M.thermoresistible__bu      GLWQPIGHQGFEVVGEPGAPVWHQLTTRDFGAALDFYRTVFGWQTQLV--
MAB_0976|M.abscessus_ATCC_1997      GLWQPLAHKGFQLVGEGGAPVWHELNTREYDRAVDFYTTVLGWNTKIE--
Mflv_4018|M.gilvum_PYR-GCK          GFWQPGTHVGFTQWGVHGTPYWFECQSKDYEKSLAFYPQVIGARTEEIGT
Rv0577|M.tuberculosis_H37Rv         GLWQANRHIGATLVNETGTLIWNELLTDKPDLALAFYEAVVGLTHSSM--
Mb0592|M.bovis_AF2122/97            GLWQANRHIGATLVNETGTLIWNELLTDKPDLALAFYEAVVGLTHSSM--
MMAR_3576|M.marinum_M               HLCQPGRSFGATCVNEPGCLTWNELATPDVDAAIAFYSQLFGWRIDFL--
                                     : *.    *    .  *   : :  :     :: **  :.*   .    

MSMEG_5616|M.smegmatis_MC2_155      -ADTDEF---RYSTASFDGDELVGVMDGAA---FLGD-APSTWTCFFGAD
Mvan_4951|M.vanbaalenii_PYR-1       -SDTDEF---RYSTALFDGEALVGVMDGSN---IPGE-APSNWCFFLGAD
MUL_0158|M.ulcerans_Agy99           -GDTDEF---RYTTASFDGEQLLGVMDGAR---LLREGVPSQWSIFFGAE
TH_0683|M.thermoresistible__bu      -SDTDEF---RYATAAFDGEDLX--XXGAA---SVAP----------CAA
MAB_0976|M.abscessus_ATCC_1997      -GDSADS---RYACAQHDGAPIAGVNDASVGQWALPEGVPAHWAVYFGTD
Mflv_4018|M.gilvum_PYR-GCK          GGDPNAVGPDRYAQLFIGESAYSGIMDSAT---LFPAEVPSFWQIYITVD
Rv0577|M.tuberculosis_H37Rv         ----EIAAGQNYRVLKAGDAEVGG--CMEPP----MPGVPNHWHVYFAVD
Mb0592|M.bovis_AF2122/97            ----EIAAGQNYRVLKAGDAEVGG--CMEPP----MPGVPNHWHVYFAVD
MMAR_3576|M.marinum_M               ----DGMP-VPYWVIRVAGRDNGGMRALTAA----DAGVPSRWLPYFVVT
                                               *                                    . 

MSMEG_5616|M.smegmatis_MC2_155      DVDKTIELIVEHGGSVVRPAEDTP-YGRLAAVADPTGAGFNLSSLQD---
Mvan_4951|M.vanbaalenii_PYR-1       DVDKTVALVTDHGGSVVRGAEDTP-YGRLAAVADPTGAGFNLSSIQS---
MUL_0158|M.ulcerans_Agy99           DVDKTLQMIADNGGAVVRGAEDTP-YGRLAAASDPTGANFNLSSLRA---
TH_0683|M.thermoresistible__bu      PAPSTPRPVS--AAPTVTTFHVAG-RVMCLSFTRPSTPRLVHHRARR---
MAB_0976|M.abscessus_ATCC_1997      DTDAGAAKAAELGGAVLAPAQDTP-YGRMALIRDTTGGTFWLCSVDS---
Mflv_4018|M.gilvum_PYR-GCK          DVAGTVARAESLGAQILMPGEETP-YGTLAALRDPLGALICLGHPPAGM-
Rv0577|M.tuberculosis_H37Rv         DADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ-
Mb0592|M.bovis_AF2122/97            DADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ-
MMAR_3576|M.marinum_M               DIAETGAAAVAAGGAVLAGPTEQP-KGVFSLLQDPQGASFLVFESDKLDP
                                                ..  :                 .    :