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GARTGYADGTFSWVDLATTEPEAATLFYGQLFGWTPEERRTADGRVYTVLCRDRQEVAGLYALPVADPAG DQTRWNSHISVADVDAAAARARALGGVILAGPLDLGDRGKMVVVRDPHGSVIHLCQPGRSFGATCVNEPG CLTWNELATPDVDAAIAFYSQLFGWRIDFLDGMPVPYWVIRVAGRDNGGMRALTAADAGVPSRWLPYFVV TDIAETGAAAVAAGGAVLAGPTEQPKGVFSLLQDPQGASFLVFESDKLDP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3576 | - | - | 100% (261) | hypothetical protein MMAR_3576 |
| M. marinum M | MMAR_4617 | - | 3e-30 | 34.02% (244) | hypothetical protein MMAR_4617 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0592 | TB27.3 | 2e-43 | 38.76% (258) | hypothetical protein Mb0592 |
| M. gilvum PYR-GCK | Mflv_4018 | - | 3e-27 | 32.79% (244) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. tuberculosis H37Rv | Rv0577 | TB27.3 | 2e-43 | 38.76% (258) | hypothetical protein Rv0577 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0976 | - | 9e-28 | 31.23% (253) | putative glyoxalase/bleomycin resistance protein |
| M. avium 104 | MAV_0132 | - | 6e-05 | 25.45% (110) | glyoxalase family protein |
| M. smegmatis MC2 155 | MSMEG_5616 | - | 2e-27 | 31.97% (244) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. thermoresistible (build 8) | TH_0683 | - | 4e-23 | 33.17% (205) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0158 | - | 5e-30 | 34.02% (244) | hypothetical protein MUL_0158 |
| M. vanbaalenii PYR-1 | Mvan_4951 | - | 1e-27 | 32.08% (240) | glyoxalase/bleomycin resistance protein/dioxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0592|M.bovis_AF2122/97 ------------------------MPKRSEYRQGTPNWVDLQTTDQSAAK
Rv0577|M.tuberculosis_H37Rv ------------------------MPKRSEYRQGTPNWVDLQTTDQSAAK
MMAR_3576|M.marinum_M ------------------------MGARTGYADGTFSWVDLATTEPEAAT
MSMEG_5616|M.smegmatis_MC2_155 ------------------------MPIRSTAPLGAPSWIDLTTSDVERAK
Mvan_4951|M.vanbaalenii_PYR-1 MSFSRRGGLHGDRSPPLRRPEETAMPVATTAPLGAPIWIDLATSDLDRAQ
MUL_0158|M.ulcerans_Agy99 ------------------------MPIRNAAPLGAPCWIDLTTSDIDRAQ
TH_0683|M.thermoresistible__bu ------------------------VPLRHGAPLGAPIWIDLGTSDLDRAL
MAB_0976|M.abscessus_ATCC_1997 ------------------------MPTRDETPLGAPAWIDLASSDLEKSK
Mflv_4018|M.gilvum_PYR-GCK -------------------------MSDYAAPVGAPIWLDLMSTDPARAA
MAV_0132|M.avium_104 ------------------------------MSEHEAKMIILSTDDLDESI
: * : : :
Mb0592|M.bovis_AF2122/97 KFYTSLFGWGYDDN--PVPGGGGVYSMATLNGEAVAAIAPMPPGAPEGMP
Rv0577|M.tuberculosis_H37Rv KFYTSLFGWGYDDN--PVPGGGGVYSMATLNGEAVAAIAPMPPGAPEGMP
MMAR_3576|M.marinum_M LFYGQLFGWTPEER--RTADG-RVYTVLCRDRQEVAGLYALPVADPAGDQ
MSMEG_5616|M.smegmatis_MC2_155 AFYGAVFGWTFETG-GPEYGG---YVTAHLEGHVVAGLMQNDPQW--NTP
Mvan_4951|M.vanbaalenii_PYR-1 QFYGAVFGWTFESA-GPEYGG---YVTAFRDDHPVAGLMVNDPQW--NAP
MUL_0158|M.ulcerans_Agy99 DFYGTVFGWTFESA-GPEYGG---YVNAARNGHPVAGLMANNPEW--QAP
TH_0683|M.thermoresistible__bu QFYGAVFGWTFESA-GPDYGG---YVNAFSQGRPVAGLMRNDPQW--NAP
MAB_0976|M.abscessus_ATCC_1997 AFYSALFGWTLQEA-GPEYGG---YINAYKDGKAVAGMITNNPEW--NAP
Mflv_4018|M.gilvum_PYR-GCK EFYHAVFGWDVEAPPQAEFGG---YQNFTVNGRRVAGLLPHMG----GVP
MAV_0132|M.avium_104 RFYSETLGMPLKFR-----DG---AHFAALDAGPVTLALATAVDH--PIP
** :* . .* : *:
Mb0592|M.bovis_AF2122/97 PIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAV
Rv0577|M.tuberculosis_H37Rv PIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAV
MMAR_3576|M.marinum_M TRWNSHISVADVDAAAARARALGGVILAGPLDLGDRGKMVVVRDPHGSVI
MSMEG_5616|M.smegmatis_MC2_155 DVWTTYLHTADAQATVAAAAAAGGSNCGGVMDVPEKGRMAMMSDAAGGFF
Mvan_4951|M.vanbaalenii_PYR-1 DAWTVYLHTADIEATVAKATAAGGTSCVAPMEIPAKGWMGMLTDPTGAFL
MUL_0158|M.ulcerans_Agy99 DNWTTYFHTADITAAAAAVTAAGGSRCVDPMEIPAKGFMCMATDPAGAFF
TH_0683|M.thermoresistible__bu DGWTTYLHTADIHATLAAATAAGGTSCMAPMEVKDKGWMAMLSDPTGGVF
MAB_0976|M.abscessus_ATCC_1997 DAWTTYFATEDIDATLQKAVTHGGTNCLPPMEVPQLGYMALFADPAGAMV
Mflv_4018|M.gilvum_PYR-GCK NVWSVYLHTADAAETVRAVEAAGGSVMVPPMPVGDMGSMMVATDPAGAVI
MAV_0132|M.avium_104 GQVVVGIKTADVDGAARAVEASGGGIVKGPYDDAHER-RAVVYDNKGNGL
: . * . . . ** . * * .
Mb0592|M.bovis_AF2122/97 GLWQANRHIGATLVNETGTLIWNELLTDKPDLALAFYEAVVGLTHSSM--
Rv0577|M.tuberculosis_H37Rv GLWQANRHIGATLVNETGTLIWNELLTDKPDLALAFYEAVVGLTHSSM--
MMAR_3576|M.marinum_M HLCQPGRSFGATCVNEPGCLTWNELATPDVDAAIAFYSQLFGWRIDFL--
MSMEG_5616|M.smegmatis_MC2_155 GLWQPAGHDGFQVFNEPGAPLYHQLTTGDYAKALQFYRDVFGWTVNTV--
Mvan_4951|M.vanbaalenii_PYR-1 GLWQPTGHRGYGIVGEHGAPVYHQLTTRGYGAALDFYRTVFGWTTETV--
MUL_0158|M.ulcerans_Agy99 GLWQPLGHRGFEIIGEAGAAVWHQLTTRDYHPAIGFYRRLFGWQTEQV--
TH_0683|M.thermoresistible__bu GLWQPIGHQGFEVVGEPGAPVWHQLTTRDFGAALDFYRTVFGWQTQLV--
MAB_0976|M.abscessus_ATCC_1997 GLWQPLAHKGFQLVGEGGAPVWHELNTREYDRAVDFYTTVLGWNTKIE--
Mflv_4018|M.gilvum_PYR-GCK GFWQPGTHVGFTQWGVHGTPYWFECQSKDYEKSLAFYPQVIGARTEEIGT
MAV_0132|M.avium_104 VFYKPLGR------------------------------------------
: :.
Mb0592|M.bovis_AF2122/97 ----EIAAGQNYRVLKAGDAEVGG--CMEPP----MPGVPNHWHVYFAVD
Rv0577|M.tuberculosis_H37Rv ----EIAAGQNYRVLKAGDAEVGG--CMEPP----MPGVPNHWHVYFAVD
MMAR_3576|M.marinum_M ----DGMP-VPYWVIRVAGRDNGGMRALTAA----DAGVPSRWLPYFVVT
MSMEG_5616|M.smegmatis_MC2_155 -ADTDEF---RYSTASFDGDELVGVMDGAA---FLGD-APSTWTCFFGAD
Mvan_4951|M.vanbaalenii_PYR-1 -SDTDEF---RYSTALFDGEALVGVMDGSN---IPGE-APSNWCFFLGAD
MUL_0158|M.ulcerans_Agy99 -GDTDEF---RYTTASFDGEQLLGVMDGAR---LLREGVPSQWSIFFGAE
TH_0683|M.thermoresistible__bu -SDTDEF---RYATAAFDGEDLX--XXGAA---SVAP----------CAA
MAB_0976|M.abscessus_ATCC_1997 -GDSADS---RYACAQHDGAPIAGVNDASVGQWALPEGVPAHWAVYFGTD
Mflv_4018|M.gilvum_PYR-GCK GGDPNAVGPDRYAQLFIGESAYSGIMDSAT---LFPAEVPSFWQIYITVD
MAV_0132|M.avium_104 --------------------------------------------------
Mb0592|M.bovis_AF2122/97 DADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ-
Rv0577|M.tuberculosis_H37Rv DADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ-
MMAR_3576|M.marinum_M DIAETGAAAVAAGGAVLAGPTEQP-KGVFSLLQDPQGASFLVFESDKLDP
MSMEG_5616|M.smegmatis_MC2_155 DVDKTIELIVEHGGSVVRPAEDTP-YGRLAAVADPTGAGFNLSSLQD---
Mvan_4951|M.vanbaalenii_PYR-1 DVDKTVALVTDHGGSVVRGAEDTP-YGRLAAVADPTGAGFNLSSIQS---
MUL_0158|M.ulcerans_Agy99 DVDKTLQMIADNGGAVVRGAEDTP-YGRLAAASDPTGANFNLSSLRA---
TH_0683|M.thermoresistible__bu PAPSTPRPVS--AAPTVTTFHVAG-RVMCLSFTRPSTPRLVHHRARR---
MAB_0976|M.abscessus_ATCC_1997 DTDAGAAKAAELGGAVLAPAQDTP-YGRMALIRDTTGGTFWLCSVDS---
Mflv_4018|M.gilvum_PYR-GCK DVAGTVARAESLGAQILMPGEETP-YGTLAALRDPLGALICLGHPPAGM-
MAV_0132|M.avium_104 --------------------------------------------------