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M. gilvum PYR-GCK Mflv_4018 (-)

annotation: glyoxalase/bleomycin resistance protein/dioxygenase
coordinates: 4270488 - 4271279
length: 263

SDYAAPVGAPIWLDLMSTDPARAAEFYHAVFGWDVEAPPQAEFGGYQNFTVNGRRVAGLLPHMGGVPNVW
SVYLHTADAAETVRAVEAAGGSVMVPPMPVGDMGSMMVATDPAGAVIGFWQPGTHVGFTQWGVHGTPYWF
ECQSKDYEKSLAFYPQVIGARTEEIGTGGDPNAVGPDRYAQLFIGESAYSGIMDSATLFPAEVPSFWQIY
ITVDDVAGTVARAESLGAQILMPGEETPYGTLAALRDPLGALICLGHPPAGM*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4018--100% (263)glyoxalase/bleomycin resistance protein/dioxygenase
M. gilvum PYR-GCKMflv_5064-1e-0826.25% (259) glyoxalase/bleomycin resistance protein/dioxygenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0935-1e-4638.58% (254) hypothetical protein Mb0935
M. tuberculosis H37RvRv0911-1e-4638.58% (254) hypothetical protein Rv0911
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0976-8e-4536.33% (256) putative glyoxalase/bleomycin resistance protein
M. marinum MMMAR_4617-1e-4841.20% (250) hypothetical protein MMAR_4617
M. avium 104-----
M. smegmatis MC2 155MSMEG_5616-7e-4440.16% (249) glyoxalase/bleomycin resistance protein/dioxygenase
M. thermoresistible (build 8)TH_0683-1e-3444.17% (163) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0158-5e-4840.80% (250) hypothetical protein MUL_0158
M. vanbaalenii PYR-1Mvan_4951-1e-4640.56% (249) glyoxalase/bleomycin resistance protein/dioxygenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0935|M.bovis_AF2122/97            ------------------------MPTRSSAPLGAPCWIDLTTSDVDRAQ
Rv0911|M.tuberculosis_H37Rv         ------------------------MPTRSSAPLGAPCWIDLTTSDVDRAQ
MMAR_4617|M.marinum_M               ------------------------MPIRNAAPLGAPCWIDLTTSDIDRAQ
MUL_0158|M.ulcerans_Agy99           ------------------------MPIRNAAPLGAPCWIDLTTSDIDRAQ
MSMEG_5616|M.smegmatis_MC2_155      ------------------------MPIRSTAPLGAPSWIDLTTSDVERAK
Mvan_4951|M.vanbaalenii_PYR-1       MSFSRRGGLHGDRSPPLRRPEETAMPVATTAPLGAPIWIDLATSDLDRAQ
TH_0683|M.thermoresistible__bu      ------------------------VPLRHGAPLGAPIWIDLGTSDLDRAL
MAB_0976|M.abscessus_ATCC_1997      ------------------------MPTRDETPLGAPAWIDLASSDLEKSK
Mflv_4018|M.gilvum_PYR-GCK          -------------------------MSDYAAPVGAPIWLDLMSTDPARAA
                                                                  :*:*** *:** ::*  :: 

Mb0935|M.bovis_AF2122/97            DFYGTVFGWAFESA-GPDYGGYINAAKGGHPVAGLMANRPEFQSPDGWAT
Rv0911|M.tuberculosis_H37Rv         DFYGTVFGWAFESA-GPDYGGYINAAKGGHPVAGLMANRPEFQSPDGWAT
MMAR_4617|M.marinum_M               DFYGTVFGWTFESA-GPEYGGYVNAARNGHPVAGLMANNPEWQAPDNWTT
MUL_0158|M.ulcerans_Agy99           DFYGTVFGWTFESA-GPEYGGYVNAARNGHPVAGLMANNPEWQAPDNWTT
MSMEG_5616|M.smegmatis_MC2_155      AFYGAVFGWTFETG-GPEYGGYVTAHLEGHVVAGLMQNDPQWNTPDVWTT
Mvan_4951|M.vanbaalenii_PYR-1       QFYGAVFGWTFESA-GPEYGGYVTAFRDDHPVAGLMVNDPQWNAPDAWTV
TH_0683|M.thermoresistible__bu      QFYGAVFGWTFESA-GPDYGGYVNAFSQGRPVAGLMRNDPQWNAPDGWTT
MAB_0976|M.abscessus_ATCC_1997      AFYSALFGWTLQEA-GPEYGGYINAYKDGKAVAGMITNNPEWNAPDAWTT
Mflv_4018|M.gilvum_PYR-GCK          EFYHAVFGWDVEAPPQAEFGGYQNFTVNGRRVAGLLPHMG--GVPNVWSV
                                     ** ::*** .:    .::*** .    .: ***:: :      *: *:.

Mb0935|M.bovis_AF2122/97            YFHTVDIGATVAKLAAAGGSSCLDPMEVPGKGFMSLAVDPSGAAFGLWQP
Rv0911|M.tuberculosis_H37Rv         YFHTVDIGATVAKLAAAGGSSCLDPMEVPGKGFMSLAVDPSGAAFGLWQP
MMAR_4617|M.marinum_M               YFHTADINAAAAAVTAAGGSRCVDPMEIPAKGFMCMATDPAGAFFGLWQP
MUL_0158|M.ulcerans_Agy99           YFHTADITAAAAAVTAAGGSRCVDPMEIPAKGFMCMATDPAGAFFGLWQP
MSMEG_5616|M.smegmatis_MC2_155      YLHTADAQATVAAAAAAGGSNCGGVMDVPEKGRMAMMSDAAGGFFGLWQP
Mvan_4951|M.vanbaalenii_PYR-1       YLHTADIEATVAKATAAGGTSCVAPMEIPAKGWMGMLTDPTGAFLGLWQP
TH_0683|M.thermoresistible__bu      YLHTADIHATLAAATAAGGTSCMAPMEVKDKGWMAMLSDPTGGVFGLWQP
MAB_0976|M.abscessus_ATCC_1997      YFATEDIDATLQKAVTHGGTNCLPPMEVPQLGYMALFADPAGAMVGLWQP
Mflv_4018|M.gilvum_PYR-GCK          YLHTADAAETVRAVEAAGGSVMVPPMPVGDMGSMMVATDPAGAVIGFWQP
                                    *: * *   :     : **:     * :   * * :  *.:*. .*:***

Mb0935|M.bovis_AF2122/97            LQHHGFEVIGEAGSPVWHQLTTRDYRSVIDFYRQVFGWRTEQI---SDTD
Rv0911|M.tuberculosis_H37Rv         LQHHGFEVIGEAGSPVWHQLTTRDYRSVIDFYRQVFGWRTEQI---SDTD
MMAR_4617|M.marinum_M               LGHRGFEIIGEAGAAVWHQLTTRDYHPAIGFYRRLFGWQTEQV---GDTD
MUL_0158|M.ulcerans_Agy99           LGHRGFEIIGEAGAAVWHQLTTRDYHPAIGFYRRLFGWQTEQV---GDTD
MSMEG_5616|M.smegmatis_MC2_155      AGHDGFQVFNEPGAPLYHQLTTGDYAKALQFYRDVFGWTVNTV---ADTD
Mvan_4951|M.vanbaalenii_PYR-1       TGHRGYGIVGEHGAPVYHQLTTRGYGAALDFYRTVFGWTTETV---SDTD
TH_0683|M.thermoresistible__bu      IGHQGFEVVGEPGAPVWHQLTTRDFGAALDFYRTVFGWQTQLV---SDTD
MAB_0976|M.abscessus_ATCC_1997      LAHKGFQLVGEGGAPVWHELNTREYDRAVDFYTTVLGWNTKIE---GDSA
Mflv_4018|M.gilvum_PYR-GCK          GTHVGFTQWGVHGTPYWFECQSKDYEKSLAFYPQVIGARTEEIGTGGDPN
                                      * *:   .  *:. :.:  :  :   : **  ::*  .:     .*. 

Mb0935|M.bovis_AF2122/97            EF---CYTTAWFDDQQLLGVMDGSS---CLPEGVPSNWTIFFGAEDVDET
Rv0911|M.tuberculosis_H37Rv         EF---CYTTAWFDDQQLLGVMDGSS---CLPEGVPSNWTIFFGAEDVDET
MMAR_4617|M.marinum_M               EF---RYTTASFDGEQLLGVMDGAR---LLPEGVPSQWSIFFGAEDVDKT
MUL_0158|M.ulcerans_Agy99           EF---RYTTASFDGEQLLGVMDGAR---LLREGVPSQWSIFFGAEDVDKT
MSMEG_5616|M.smegmatis_MC2_155      EF---RYSTASFDGDELVGVMDGAA---FLGD-APSTWTCFFGADDVDKT
Mvan_4951|M.vanbaalenii_PYR-1       EF---RYSTALFDGEALVGVMDGSN---IPGE-APSNWCFFLGADDVDKT
TH_0683|M.thermoresistible__bu      EF---RYATAAFDGEDLX-XXGAAS---VAPCAAPAPSTP--RPVSAAPT
MAB_0976|M.abscessus_ATCC_1997      DS---RYACAQHDGAPIAGVNDASVGQWALPEGVPAHWAVYFGTDDTDAG
Mflv_4018|M.gilvum_PYR-GCK          AVGPDRYAQLFIGESAYSGIMDSAT---LFPAEVPSFWQIYITVDDVAGT
                                          *:    .        ..:         .*:         ..   

Mb0935|M.bovis_AF2122/97            LRVICDNGGSVVRAAENTPYGRLAAAADPMGVVFNLSSLQA--
Rv0911|M.tuberculosis_H37Rv         LRVICDNGGSVVRAAENTPYGRLAAAADPMGVVFNLSSLQA--
MMAR_4617|M.marinum_M               LQMIADNGGAVVRGAEDTPYGRLAAASDPTGANFNLSSLRA--
MUL_0158|M.ulcerans_Agy99           LQMIADNGGAVVRGAEDTPYGRLAAASDPTGANFNLSSLRA--
MSMEG_5616|M.smegmatis_MC2_155      IELIVEHGGSVVRPAEDTPYGRLAAVADPTGAGFNLSSLQD--
Mvan_4951|M.vanbaalenii_PYR-1       VALVTDHGGSVVRGAEDTPYGRLAAVADPTGAGFNLSSIQS--
TH_0683|M.thermoresistible__bu      VTTFHVAGRVMCLSFTRPSTPRLVHHRARR-------------
MAB_0976|M.abscessus_ATCC_1997      AAKAAELGGAVLAPAQDTPYGRMALIRDTTGGTFWLCSVDS--
Mflv_4018|M.gilvum_PYR-GCK          VARAESLGAQILMPGEETPYGTLAALRDPLGALICLGHPPAGM
                                           *  :      ..   :.