For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSGRWEAGNADGNGGSAGLIGSGGAGGDGGSGGATGAGGEGGDAGASGSINGNAGDPGNSGERGAVGKPG APG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0378 | - | - | 100% (73) | CONSERVED HYPOTHETICAL GLYCINE RICH PROTEIN |
| M. tuberculosis H37Rv | Rv1068c | PE_PGRS20 | 8e-16 | 55.22% (67) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3590c | PE_PGRS58 | 1e-15 | 51.25% (80) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0385 | - | 4e-40 | 100.00% (73) | glycine rich protein |
| M. gilvum PYR-GCK | Mflv_2178 | - | 2e-13 | 56.45% (62) | hypothetical protein Mflv_2178 |
| M. leprae Br4923 | MLBr_01556 | infB | 2e-08 | 41.18% (68) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 9e-09 | 43.28% (67) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_3316 | - | 2e-15 | 53.52% (71) | PE-PGRS family protein |
| M. avium 104 | MAV_2780 | - | 2e-09 | 48.44% (64) | hypothetical protein MAV_2780 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-11 | 45.21% (73) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-10 | 50.75% (67) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2957 | - | 2e-15 | 52.05% (73) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-12 | 50.75% (67) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mflv_2178|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M --------MAFVLVAPEMVTAAASDLANIGSAIN------TANTAVAAPT
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mflv_2178|M.gilvum_PYR-GCK -----------------------------------------MSGTAHAPG
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------MMFLAPPGGPG
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------MSIIDFILNLFRDPVE
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -------------------MAGKARVHELAKELGVTSKEVLARLNEQGEF
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M AELLAAG-TDEVSEAIASLFSGHA------------LDYQNLGARMTAFH
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mflv_2178|M.gilvum_PYR-GCK KTRLFANVTVAVG-----------------------LGGAALGAAALLAP
Mvan_1264|M.vanbaalenii_PYR-1 PISAAIQLTSTGSEATEP------------------WYVVSFGGSGAPTP
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AASYVADPEAALANAGLS-----------------AVSAAQVGAVMPVVA
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 VKSASSTVEAPVARRLRESFGG--------------IKPAADKGAEQVAT
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M DQFVAALT---------------AGGGLYSSAEAAAATPLQDLLNVVNAP
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mflv_2178|M.gilvum_PYR-GCK QAS--------------------AAPEEWLPAGPSSECPPP---------
Mvan_1264|M.vanbaalenii_PYR-1 NNL---------------------AASLVDLSGTSCG-------------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESVASN----------------YGYQSQWVNTG-----------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 KAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHS-----------
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M TQAL--------------------------------LGRPLIGDGADGTA
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mflv_2178|M.gilvum_PYR-GCK ---------------------------------------------TDGCA
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------LICNGQDGTG
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------NPIHDLSGNLQ
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -----------------------------------------AAVVPIVAG
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M PGQAGGAGGLLYGNGGNGAAGTNPGVAGGAGGAAGLIG-NGGAGGIGGAG
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Mflv_2178|M.gilvum_PYR-GCK NVAAVGG-----VHGAQGPANLATPQTSGSPLFRPLFG-NGADAPADCVG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MUL_2957|M.ulcerans_Agy99 -------------------MSSDTGEPGGQDD-------QGGAGGRGGAG
TH_3810|M.thermoresistible__bu --------------------VDGDGGSGGRTGLFSKLS-RGGDGGDGGLG
MAB_4284c|M.abscessus_ATCC_199 NYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSG
MAV_2780|M.avium_104 -------------------------MFGGAAMLVLAVGCGGGHKGGPSTT
MLBr_01556|M.leprae_Br4923 EGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPG
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M GSGGAGGTGGWL--YGNGGAGGAGGAGAPGLVSFNGSNGGNGGNGGAAGW
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGGLL--MGIGGAGGAGGVGADG--TSAHVDGGTGGTGGTGG-
Mflv_2178|M.gilvum_PYR-GCK -NACNGRDGGLI--WGNGGAG-----------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVGAPGVAGATGATGVT
MUL_2957|M.ulcerans_Agy99 GRGGDGGP------------------------------------------
TH_3810|M.thermoresistible__bu GNGGHGGGTGIISLLSLAGNG-----------------------------
MAB_4284c|M.abscessus_ATCC_199 NVDSFNRGPLLDLSFGDLQFGNRDTTAIG---------------------
MAV_2780|M.avium_104 STTTPTTTP-----------------------------------------
MLBr_01556|M.leprae_Br4923 PAPKPGGRPPRVGNNPFSSAQSVARPIPRP--------------------
Rv0378|M.tuberculosis_H37Rv --------------------------------------MSGRW-------
Mb0385|M.bovis_AF2122/97 --------------------------------------MSGRW-------
MMAR_3316|M.marinum_M WGTGGAGGAGGEGGAAGGGPAGIAYGQTGGVGGNGGNGGNGGW-------
MSMEG_0868|M.smegmatis_MC2_155 -GTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAG
Mflv_2178|M.gilvum_PYR-GCK -----------------------------------ANGGH----------
Mvan_1264|M.vanbaalenii_PYR-1 SNVTGGNGADAVGYGATGAAGAAGAAGAAGKAGAVGSAGTAGS-------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu -----------------------------------GNGGNGYR-------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ---------------PAPRPSASPSSMSPRPGGAVGGGGPR---------
Rv0378|M.tuberculosis_H37Rv ---EAGNA----------DGN----------------GGSAGLIGSGG--
Mb0385|M.bovis_AF2122/97 ---EAGNA----------DGN----------------GGSAGLIGSGG--
MMAR_3316|M.marinum_M ---FAGNAGAGGNGGVGGDGNAADNGLVGGTGGVGGAGGSAGLFGDGG--
MSMEG_0868|M.smegmatis_MC2_155 PNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGT
Mflv_2178|M.gilvum_PYR-GCK -------------------------------------GGNAGLVGNGG--
Mvan_1264|M.vanbaalenii_PYR-1 ----AGAPG---------------------------VWGNAGLPGAAG--
MUL_2957|M.ulcerans_Agy99 -------------------------------------GGAPGIGGRPG--
TH_3810|M.thermoresistible__bu ------------------------------------TTDNNALDGGHG--
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------DGAVAVGGSNSGP
MAV_2780|M.avium_104 --------------------------------------STSVVPSTTP--
MLBr_01556|M.leprae_Br4923 -------------------------------------PPRTGVPRPGGGR
:
Rv0378|M.tuberculosis_H37Rv -----AGGDGGSGG------ATGAGGEGGDA----------------GAS
Mb0385|M.bovis_AF2122/97 -----AGGDGGSGG------ATGAGGEGGDA----------------GAS
MMAR_3316|M.marinum_M -----AGGQGGDGGGVTGLVGAGHGGAGGDG----------------GRA
MSMEG_0868|M.smegmatis_MC2_155 VDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGD
Mflv_2178|M.gilvum_PYR-GCK -----RGGDATTPG--------RSGGHGGNG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----AAGGAGAIGTAGVAGAAGTAGATGGTG---------------VGGN
MUL_2957|M.ulcerans_Agy99 -----EGGPGGAGG---------EPGPGGTS-------------------
TH_3810|M.thermoresistible__bu -------GNGGNVGFFSLFNLGGAGGWGGSG-------------------
MAB_4284c|M.abscessus_ATCC_199 ----IASGQGSTAVNGDVRDSNIINADHGSN------------------V
MAV_2780|M.avium_104 ------GGGGTVPG----------GPTGGGG-------------------
MLBr_01556|M.leprae_Br4923 -PGAPVGGRSDAGGGNYRGGGVGALPGGGSG-----------------GF
* . *
Rv0378|M.tuberculosis_H37Rv GSINGNAGDPGNSGER--------GAVGKPGAPG----------------
Mb0385|M.bovis_AF2122/97 GSINGNAGDPGNSGER--------GAVGKPGAPG----------------
MMAR_3316|M.marinum_M GWLSGNAGAGGGGGAG--------GAVDNHGSGGDYAGGGGAGGSGGAAG
MSMEG_0868|M.smegmatis_MC2_155 GGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGR-GGDGIDGGTGGAGG
Mflv_2178|M.gilvum_PYR-GCK GRLWGNGGDGGNGAPG----------VLGPAGTAPIPPSSLPAATG----
Mvan_1264|M.vanbaalenii_PYR-1 GGAGQAGGIGGTGAAG---------AAGQAGTAGETGVTGGVGGIGGQGT
MUL_2957|M.ulcerans_Agy99 ----GQPGQPGQPGQP-----------GQPGAPGH---------------
TH_3810|M.thermoresistible__bu --VDGVDVVGGNPDGG------------TPGAHGESHTPGVYTDRQG---
MAB_4284c|M.abscessus_ATCC_199 GVDQSQTRVGGDYTN-----------VSGHGSADIDKSVTVVDDHSQRNT
MAV_2780|M.avium_104 ------PGGGGGSIPG----------------------------------
MLBr_01556|M.leprae_Br4923 RGRPGGGGHGGGGRPG--------QRGGAAGAFGRPGGAPRRGRKSKRQK
*
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M L--FGNGAAGGAG--GAGGASQTFTGAGGAGGTGGAGGWLYGNGGAGG--
MSMEG_0868|M.smegmatis_MC2_155 MGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGK
Mflv_2178|M.gilvum_PYR-GCK ----------------TRGDSPPYGYGNLVGGDGGT-------GADGGRY
Mvan_1264|M.vanbaalenii_PYR-1 EG--GTGGVGGVGGVGATGGAGGVGGKGIQGGQGLQG----GQGGDGGTG
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu ----------------EDGEDGTGTGIGGRGGNGGS--------------
MAB_4284c|M.abscessus_ATCC_199 TNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIGTS-------TSAGGSA
MAV_2780|M.avium_104 ------------------------------GPTGG---------------
MLBr_01556|M.leprae_Br4923 RQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQA
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M AGGASGAGIGGDSL-GGSGGNGGNGGISGLIGNGGAGG---AGGNGSAAG
MSMEG_0868|M.smegmatis_MC2_155 ASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAAS
Mflv_2178|M.gilvum_PYR-GCK AFGAN---WSLDLPVGGAGGAGGWANSIDGSATG----------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGDATSMGEAGATGGKGGNGGNGGRGSLFGRG----------------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu SSGTHPMAEDGEHVKALDGRPGLDG-------------------------
MAB_4284c|M.abscessus_ATCC_199 AVGGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 LFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDR----------
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M YN-------------------------------GYSGNGGNGGNGGAAQL
MSMEG_0868|M.smegmatis_MC2_155 ANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAY
Mflv_2178|M.gilvum_PYR-GCK ------------------------------------GNGGDGGNG-----
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------GNAGNGGNGGTGGN
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu ------------------------------------GNGSHGGNG-----
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------LAGNAGLAGNAGLAGN
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ----------------------------ELLEPFDLTYGEDQGDEDELQV
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M IGAGGGGGVAGIG-GAGGTGAAAGVTGSAGASGVGGRLYSGNGIPDIFGR
MSMEG_0868|M.smegmatis_MC2_155 DPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQ
Mflv_2178|M.gilvum_PYR-GCK --------------AFGGRGGNG---GAGGSAYGRGGITTG---------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGTGGTGGNG-GTGGTGGTGGIGGAGSTGGTGGTGGTG---------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu -----------------GHGGRGGFLGIGGS-------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG---------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 RPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDG
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M PLIGDGADGAPGTGQAGGDGGWLYGNGGAGGSGAAGQAGGAGGAAGLIGN
MSMEG_0868|M.smegmatis_MC2_155 HSTGQTDTG--GNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGH
Mflv_2178|M.gilvum_PYR-GCK -----------GNGGAGGHG----STGAAGGRGGDGAS--ASGGYAVGGN
Mvan_1264|M.vanbaalenii_PYR-1 -----------GTGGTGGTGGTG-GTGGTGGTGGKGGTGGTGGDGGTGGT
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------GGWGGHGGNGGDTDADGG-----N
MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNA
MAV_2780|M.avium_104 --------------------------GGPGGGGG----------------
MLBr_01556|M.leprae_Br4923 SERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINH
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M GGAGGTGGSGAAGGSGAAGGNGGAGGWLFGNGGTGGTGGDAVAGLPGLNG
MSMEG_0868|M.smegmatis_MC2_155 GGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAG
Mflv_2178|M.gilvum_PYR-GCK GGDGGRGGAGATGGTGGTGGAG-------GDGGRGG--------LLGGHG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGTGGTGGTGGTGGAGDGLGGTGGTGGTGGFGGQGGQGGTG
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu GGDGGNGGSAGRGGTGG---------------------------LRGVFG
MAB_4284c|M.abscessus_ATCC_199 AVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSG
MAV_2780|M.avium_104 SIPGGPTGGGGPG------------------------------------G
MLBr_01556|M.leprae_Br4923 AQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISA
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M GNGGNGGAG------GAAGWWGHGGIGGQGGTG---------GAAGGNPG
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEAL
Mflv_2178|M.gilvum_PYR-GCK GKGGNAGLG------------GNGGTGGTGGVG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGQGGLG------GVGGTGGTGGTGGTGGQG-----------------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu INGGNGRAG----------------LGGRGXXX-----------------
MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVG----------GGAHTGVGGGVSTG-----------------
MAV_2780|M.avium_104 GGGSIPGVG-----------------GGGGGPG-----------------
MLBr_01556|M.leprae_Br4923 KVGTNIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATV
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M IYAGNAG-------TGGDGGAGGWLFGDAGAGGQGGTGGA----ANDPLV
MSMEG_0868|M.smegmatis_MC2_155 IRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQAS
Mflv_2178|M.gilvum_PYR-GCK ----------------GDGGVGGGILTATGVVGAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GTGGTGGTGG-TGGTGGAGGDGGLGG-----------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu ----------------XGGGVGAAVRSGNG--------------------
MAB_4284c|M.abscessus_ATCC_199 ----------VGVGSHVGGGISESLGGSGSVGGSTAVGGG----------
MAV_2780|M.avium_104 ----------------GGGGCVGNVCGAYP--------------------
MLBr_01556|M.leprae_Br4923 LVQRGTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSS-------PVQ
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M TSSTGGSGGAGGNGGAAGLFGAGGAGGTG-GTAGDGYLIGGDGGNGGQGG
MSMEG_0868|M.smegmatis_MC2_155 GTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGG
Mflv_2178|M.gilvum_PYR-GCK -----GSGGAGGTGGRGGD--------------------GGDGGQAGRGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LGGFGGVGGTGGQGGQGGPGGSTG----------GAGGAGGQAGVAG
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu -----VFSGGGGTPS------------------------AGFGVPTTIQF
MAB_4284c|M.abscessus_ATCC_199 --AHTGVGGGVSTGVGVGSHVGGGISES----------LGGSGSVGGSTA
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 VIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLED
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M YGG-----------WLAGSGGAGGTAGDGGAG-----IYPGGAGG-----
MSMEG_0868|M.smegmatis_MC2_155 LGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQ
Mflv_2178|M.gilvum_PYR-GCK AGG------------LAGRSGADG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1 KGG------------LFGGSGSAGTAGVTGASGASGGKGAQGATG-----
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu PAG-------------SCTSRAVSREG-----------------------
MAB_4284c|M.abscessus_ATCC_199 VGG-------------GAHTGVGGGVN-----------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 LDSALKETSQLNLILKGDNAGTVEALEEALMG------------------
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M ------TGGSGGAARFFGDGGAAGTGGVGGFG----------SKYVAGSG
MSMEG_0868|M.smegmatis_MC2_155 SGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNT
Mflv_2178|M.gilvum_PYR-GCK ---------------------------------------------EAGDA
Mvan_1264|M.vanbaalenii_PYR-1 ------AQGATGAQGATGATGASGAQGSAGSAG---------SAGVAGSA
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------IMPSSR
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------TGVGV
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ---------------------------------------IQVDDEVALRV
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M GSGGTGGAAGWLIGNGGAGGQGGVAGTPDGVNR--VFGGTGGAGGTG---
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGG
Mflv_2178|M.gilvum_PYR-GCK GTGGRGGAG-------GSGGKGGISGT----------GTPGGAGQSG---
Mvan_1264|M.vanbaalenii_PYR-1 GTTGAQGSAGTNGAN-GANGSQGAAGKAGATGTTGATGAAGDAGDPG---
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu AASARAGAACASSTSRSRRSFCCSRA------------------------
MAB_4284c|M.abscessus_ATCC_199 GSHVGGGISESLGGSGSVGGSTAVGGGAHTSAINDALGGSG---------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 IDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLV
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M -GTAGWLYGSGGSGGAG----------GAGTASIYPGSTGGNGGNGGNGG
MSMEG_0868|M.smegmatis_MC2_155 KGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGG
Mflv_2178|M.gilvum_PYR-GCK -----------------------------------QSATGRSGGAGGEGG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------SEAVDINGGAGGAGGAGGEGG
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------SVGGSTAVGGGAH
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 IYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSG
Rv0378|M.tuberculosis_H37Rv --------------------------------------------------
Mb0385|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M AAQVIGTGG--------TGGTAGTGGAGGPDDPPNNIPAGNDGQDGVGG-
MSMEG_0868|M.smegmatis_MC2_155 NTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGT
Mflv_2178|M.gilvum_PYR-GCK -----------------------AGGAGGTDD------------------
Mvan_1264|M.vanbaalenii_PYR-1 EGGAGGAGG--------DGSEGGAGGSGGAGGSGTGGAGGAGGSGGSGGS
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASE
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 VVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSD
Rv0378|M.tuberculosis_H37Rv ----------------------------------
Mb0385|M.bovis_AF2122/97 ----------------------------------
MMAR_3316|M.marinum_M -AGGSGGLVFGNSGG-------------------
MSMEG_0868|M.smegmatis_MC2_155 TAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
Mflv_2178|M.gilvum_PYR-GCK ----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGGAAGDSD--------------------
MUL_2957|M.ulcerans_Agy99 ----------------------------------
TH_3810|M.thermoresistible__bu ----------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAHTTLPGAEHH----------------------
MAV_2780|M.avium_104 ----------------------------------
MLBr_01556|M.leprae_Br4923 IKEGDVIESYELVEKQRA----------------