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SISDRAAQLVAARTPFVRATVVRAQQPTSARPGDEAILLADGTIEGFVGGHCAQNSVRKAAMGVLQAGES VLLRVLPDGDVHFPEAPGACVVVNPCLAGGSLEIFLTPQLPAPLIQIYGETPIADALIELCGLLGYDARR DTDPADTDALPTAIVIASHGGPEAEIIRTALDNGVGYVGLVASTVRGASILDSLDLSDAERARVHTPVGL AIGAKTPAEIAVSIAAELIATLRGGGPRGRKALADENGGA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0372c | - | - | 100% (251) | hypothetical protein Rv0372c |
M. tuberculosis H37Rv | Rv0376c | - | 3e-18 | 29.55% (264) | hypothetical protein Rv0376c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0379c | - | 1e-139 | 99.60% (251) | hypothetical protein Mb0379c |
M. gilvum PYR-GCK | Mflv_1574 | - | 1e-15 | 29.59% (267) | hypothetical protein Mflv_1574 |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2924c | - | 2e-05 | 38.24% (68) | hypothetical protein MAB_2924c |
M. marinum M | MMAR_0658 | - | 1e-112 | 82.52% (246) | hypothetical protein MMAR_0658 |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | MSMEG_0747 | - | 1e-92 | 71.13% (239) | carbon monoxide dehydrogenase F protein |
M. thermoresistible (build 8) | TH_0177 | - | 1e-48 | 84.91% (106) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_0114 | - | 1e-112 | 83.33% (240) | hypothetical protein MUL_0114 |
M. vanbaalenii PYR-1 | Mvan_5182 | - | 1e-11 | 26.12% (268) | hypothetical protein Mvan_5182 |
CLUSTAL 2.0.9 multiple sequence alignment Rv0372c|M.tuberculosis_H37Rv ------MSISDRAAQLVAARTPFVRATVVRAQQPTSARPGDEAILLADGT Mb0379c|M.bovis_AF2122/97 ------MSISDRAAQLVAARTPFVRATVVRAQQPTSARPGDEAILLADGT MMAR_0658|M.marinum_M ------MTISERAAQLLAARTPFVHATVVRAQPPTSAYPGDEAILLPDGT MUL_0114|M.ulcerans_Agy99 ----MQMTISERAAQLLAARTPFVHATVVRAQPPTSAYPGDEAILLPDGT TH_0177|M.thermoresistible__bu -----------------------VHATVVRAQQPTSAHPGDEAILLPDGT MSMEG_0747|M.smegmatis_MC2_155 MTPMTPMRLHDRVTELRRARTPFVHATVVRAQQPTSAHPGDEAILLPDGT Mflv_1574|M.gilvum_PYR-GCK ---------------MWEAGGTAGLSTVVRTMKSAPRPPGAAMVVSPDGT Mvan_5182|M.vanbaalenii_PYR-1 -----MRDVLDELLAVWRSGETAGLSTVVRTMQSAPRPPGAAMVVGPDGA MAB_2924c|M.abscessus_ATCC_199 -----MKDILRDLIAVLEGGGTAALARVVEVSGAVPREPGAAMIVPADGP : **.. ... ** :: .**. Rv0372c|M.tuberculosis_H37Rv IEGFVGGHCAQNSVRKAAMGVLQAGESVLLRVLP---------------- Mb0379c|M.bovis_AF2122/97 IEGFVGGHCAQNSVRKAAMGVLQAGESVLLRVLP---------------- MMAR_0658|M.marinum_M IEGFVGGQCAQNSVRKAALGVLQAGESVLLRVLP---------------- MUL_0114|M.ulcerans_Agy99 IEGFVGGQCAQNSVRKAALGVLQAGESVLLRVLP---------------- TH_0177|M.thermoresistible__bu IEGFVGGHCAQNSVRKAALGVLQTRQSVLLRVLP---------------- MSMEG_0747|M.smegmatis_MC2_155 IEGFVGGHCAQNSVRQAALGALQVGQSVLLRVLP---------------- Mflv_1574|M.gilvum_PYR-GCK VAGSVSGGCVEGAVYETANEVITGGAPHLQRYGVSDDDAFSVGLTCGGII Mvan_5182|M.vanbaalenii_PYR-1 VAGSVSGGCVEAAVYEVANDVVASGVPELQRYGISDDDAFTVGLTCGGTI MAB_2924c|M.abscessus_ATCC_199 VVGSLSGGCVEAAVIETAREVLAIGLCVSERFGI--DDGIAPGLTCGGEI : * :.* *.: :* :.* .: * Rv0372c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0379c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0658|M.marinum_M -------------------------------------------------- MUL_0114|M.ulcerans_Agy99 -------------------------------------------------- TH_0177|M.thermoresistible__bu -------------------------------------------------- MSMEG_0747|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1574|M.gilvum_PYR-GCK DIFTEPVSRNTFPQLRDVATAIAEHRAVAVATVIAHPDPARVGRRIIVGT Mvan_5182|M.vanbaalenii_PYR-1 DVFTEPVSRETFPQLQQVADDIAAHRPVAVATVIVHPDPKRVGLRLVVGR MAB_2924c|M.abscessus_ATCC_199 EVVTEHIGAERFPLLRELRSALVAGEPMGLVSTLSG-----IPDWALVR- Rv0372c|M.tuberculosis_H37Rv ----------------DGDVHFPEAPGACVVVNPCLAG----GSLEIFLT Mb0379c|M.bovis_AF2122/97 ----------------DGDVHFPEAPGACVVVNPCLAG----GSLEIFLT MMAR_0658|M.marinum_M ----------------DGDVHFPEAPGACVVVNPCLSG----GSLEIFLT MUL_0114|M.ulcerans_Agy99 ----------------DGDVHFPEAPGACVVVNPCLSG----GSLEIFLT TH_0177|M.thermoresistible__bu ----------------GGDVHFPEAPGACVVVNPCLSG----GALEIFLT MSMEG_0747|M.smegmatis_MC2_155 ----------------DGDVSFPETPGACVVVNHCLSG----GALEIFLD Mflv_1574|M.gilvum_PYR-GCK DSRQGSVGSPRADDAVADDARGLLLAGRSAVLSYGPDGQRQDAGMEVFVS Mvan_5182|M.vanbaalenii_PYR-1 DSRHGSLGSSRTDDAVTDDARGLLLAGRSGVLTYGADGQRQESGMEVFVC MAB_2924c|M.abscessus_ATCC_199 ------AGEPAPWPQIEGDIVSLIRAGRSAVAGADRCEPDQSDLPRVFVQ .* .* . * .:*: Rv0372c|M.tuberculosis_H37Rv PQLPAPLIQIYGETPIADALIELCGLLGYDARRDTDPADTDAL------- Mb0379c|M.bovis_AF2122/97 PQLPAPLIQIYGETPIADALIELCGLLGYDARRDTDPADTDAL------- MMAR_0658|M.marinum_M PQLPAPLVRIYGATPIAEALIEVCGVLGYDARRDSDPVGAAAL------- MUL_0114|M.ulcerans_Agy99 PQLPAPLVRIYGATPIAEALIEVCGVLGYDARRDSDPVGAAAL------- TH_0177|M.thermoresistible__bu PELPAPLIRLYXRQP----------------RR----------------- MSMEG_0747|M.smegmatis_MC2_155 PQVPAPLVGVFGGSPIADALVEVTAVLGYDVRRLDAPDPSALDG------ Mflv_1574|M.gilvum_PYR-GCK SYAPRPRMLVFGAIDFAAALAHQAAFLGYRVTVCDARPVFATEARFPAAE Mvan_5182|M.vanbaalenii_PYR-1 SHAPRPKMLVFGAIDFASALARQATFLGYRVTVCDARPVFATAARFPAAE MAB_2924c|M.abscessus_ATCC_199 AFAAPPRMILAGANAFVRALSRTGSQLGYRVTVVDAREVFATPAHFPYAD . . * : : Rv0372c|M.tuberculosis_H37Rv ---------------------PTAIVIASHGGPEAEI------IRTALDN Mb0379c|M.bovis_AF2122/97 ---------------------PTAIVIASHSGPEAEI------IRTALDN MMAR_0658|M.marinum_M ---------------------PTAVVIASHGGPEAEN------IRAALDN MUL_0114|M.ulcerans_Agy99 ---------------------PTAVVIASHGGPEAEN------IRAALDN TH_0177|M.thermoresistible__bu -----------------------------AGGP----------------- MSMEG_0747|M.smegmatis_MC2_155 ---------------------ASALVIASLGGPEADL------IRAALDA Mflv_1574|M.gilvum_PYR-GCK EVVVDWPHRYLAAQADLGLIDARTAICVLTHDPKFDVPVLEVALRLPDAG Mvan_5182|M.vanbaalenii_PYR-1 EVVVDWPDRYLRAQAEQGEIDSRTAVCVLTHDPKFDVPVLEVALRLPELD MAB_2924c|M.abscessus_ATCC_199 EVVVDWPHRYLRAEAAGGRVDARTVVCVLTHDPKFDVPMLAAALTVAPVA .* Rv0372c|M.tuberculosis_H37Rv GVGYVGLVASTVRGASILDSLDLSDAERARVHTPVGLAIGAKTPAEIAVS Mb0379c|M.bovis_AF2122/97 GVGYVGLVASTVRGASILDSLDLSDAERARVHTPVGLAIGAKTPAEIAVS MMAR_0658|M.marinum_M GVGYIGLVASKVRGAAVLDSLGLSATERARIRTPVGLAIGAKTPAEIAVA MUL_0114|M.ulcerans_Agy99 GVGYIGLVASKVRGAAVLDSLGLSATERARIRTPVGLAIGAKTPAEIAVA TH_0177|M.thermoresistible__bu --------AHPRR-----------AGRRGGLRRPG----GQPHPGRCGA- MSMEG_0747|M.smegmatis_MC2_155 GIGYIGLVASRRRGSAILDGLNLTESERARMHTPVGLDIGARTPAEIAVS Mflv_1574|M.gilvum_PYR-GCK YIGVMGSRRTHEDRMSRLREAGLTETELARLASPIGLDLGARTPEETAVS Mvan_5182|M.vanbaalenii_PYR-1 YIGVMGSRRTHHDRVRRLREAGLTDKELARLSSPIGLDLGARTPEETAVS MAB_2924c|M.abscessus_ATCC_199 FVGALGSRRTHTDRMARLREQGVTDDQLGRLRSPLGLDLNARTPEETAIS . . : * . * . . Rv0372c|M.tuberculosis_H37Rv IAAELIATLR-GGG------------------------------------ Mb0379c|M.bovis_AF2122/97 IAAELIATLR-GGG------------------------------------ MMAR_0658|M.marinum_M IAAEIIAAVRAGGGGRPAPVDATAAEAVDPVCGMTVLIGPATEHLRLAGA MUL_0114|M.ulcerans_Agy99 IAAEIIAAVRAGGG---------------------------------AGP TH_0177|M.thermoresistible__bu -----------GGG------------------------------------ MSMEG_0747|M.smegmatis_MC2_155 IAAEVIATVRAHGR------------------------------------ Mflv_1574|M.gilvum_PYR-GCK IAAEIIARRWGGGG------------------------------------ Mvan_5182|M.vanbaalenii_PYR-1 IAAEIIARRWGGDG------------------------------------ MAB_2924c|M.abscessus_ATCC_199 IAAQIIAETSGGSG------------------------------------ . Rv0372c|M.tuberculosis_H37Rv ------PRGRKALADENGGA Mb0379c|M.bovis_AF2122/97 ------PRGRKALADENGGA MMAR_0658|M.marinum_M DYWFCCPACRTAFSDRNGGA MUL_0114|M.ulcerans_Agy99 RRWMRLPPRR---WTRCAG- TH_0177|M.thermoresistible__bu ------PAHRL--------- MSMEG_0747|M.smegmatis_MC2_155 -------------------- Mflv_1574|M.gilvum_PYR-GCK -----RPLTETDGRIHHEA- Mvan_5182|M.vanbaalenii_PYR-1 -----RPLSQTDGRIHHPA- MAB_2924c|M.abscessus_ATCC_199 -----RPLSDIDGPIHR---