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RSMGFLHRACRAPSSLPAPLMARPGRSVLARPAATPPGPLCATTRPRPPQGNQPPASRISNFPPKRHKTR VLAAAEDEVSAAVAALISAHGRRHHSLNNQAAAFHGQFAQNLNVGAGSCASAETTADAPTQALLGPADRQ RRQRRAVRQWLVRWAAHPGRATRGFHNHRQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0335c | PE6 | - | 100% (171) | PE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv0124 | PE_PGRS2 | 3e-14 | 54.67% (75) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv1325c | PE_PGRS24 | 6e-14 | 51.52% (66) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0342c | PE6 | 8e-99 | 100.00% (171) | PE family protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4398 | - | 8e-15 | 55.26% (76) | PE-PGRS family protein, PE_PGRS9_3 |
| M. avium 104 | MAV_2923 | - | 5e-06 | 43.40% (53) | Excalibur protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0212 | - | 5e-15 | 55.26% (76) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4398|M.marinum_M ---MSFVNVTPEAVAAAASDLTG---------------------------
MUL_0212|M.ulcerans_Agy99 ---MSFVNVTPEAVAAAASDLTG---------------------------
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv MRSMGFLHRACRAPSSLPAPLMARPGRSVLARPAATPPGPLCATTRPRPP
Mb0342c|M.bovis_AF2122/97 MRSMGFLHRACRAPSSLPAPLMARPGRSVLARPAATPPGPLCATTRPRPP
MMAR_4398|M.marinum_M ---IGSVLGEANAVAARATTTVLAAGGDEVSAAIAALFSFHGQSYQTLGA
MUL_0212|M.ulcerans_Agy99 ---IGSVLGEANAVAARATTTVLAAGGDEVSAAIAALFSFHGQSYQTLGA
MAV_2923|M.avium_104 ---------------------MVPAAADEVSALTAAQFAAHAQMYQAVSA
Rv0335c|M.tuberculosis_H37Rv QGNQPPASRISNFPPKRHKTRVLAAAEDEVSAAVAALISAHGRRHHSLNN
Mb0342c|M.bovis_AF2122/97 QGNQPPASRISNFPPKRHKTRVLAAAEDEVSAAVAALISAHGRRHHSLNN
::.*. ***** ** :: *.: ::::.
MMAR_4398|M.marinum_M QAEAFHAQFAQLMANGAGTYASAEAANAAPFQGLLGAVNAPVQTLTGRPL
MUL_0212|M.ulcerans_Agy99 QAEAFHAQFAQLMANGAGTYASAEAANAAPFQGLLGAVNAPVQTLTGRPL
MAV_2923|M.avium_104 QAAAIHEAFVNTLLTSSGSYAATEAANAAAAL------------------
Rv0335c|M.tuberculosis_H37Rv QAAAFHGQFAQNLNVGAGSCASAETTADAPTQALLGPADRQRRQRR----
Mb0342c|M.bovis_AF2122/97 QAAAFHGQFAQNLNVGAGSCASAETTADAPTQALLGPADRQRRQRR----
** *:* *.: : .:*: *::*:: *.
MMAR_4398|M.marinum_M IGNGANGAPGTGANGGAGGWLIGNGGAGGSGAPGLNGGAGGAAGLIGTGG
MUL_0212|M.ulcerans_Agy99 IGNGANGAPGTGANGGAGGWLIGNGGAGGSGAPGLNGGAGGAAGLIGTGG
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv ---------------AVRQWLVRWAAHPGRATRGFHNHRQ----------
Mb0342c|M.bovis_AF2122/97 ---------------AVRQWLVRWAAHPGRATRGFHNHRQ----------
MMAR_4398|M.marinum_M AGGAGGSSSTVNGGVGGTGGAGGWLLGNGGAGGAGGASAIPLGPDLIGKG
MUL_0212|M.ulcerans_Agy99 AGGAGGSSSTVNGGLGGTGGAGGWLLGNGGAGGAGGASAIPLGPDLIGKG
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GAGGAGGSGGLFGAGGLGGAGGFGGSAGGAGGQGGAGGLLSGLVGAGGGH
MUL_0212|M.ulcerans_Agy99 GAG---GPGGLFGAGGLGGAGGFGGSGGGAGGQGGAGGLLSGLVGAGGGH
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GGTGGYGGGAGGAGGNAGLLAGTGGSGGTGGYGGGAGGAGGNAGLLFGNG
MUL_0212|M.ulcerans_Agy99 GGTGGYGGGAGGAG------------------------------------
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GAGGAGATGGGNTGGIGGDGGNAGMLFSNGGAGGAGGASELADGGAGGAG
MUL_0212|M.ulcerans_Agy99 ------ATGGGNTGGIGGDGGSAGMLFSNSGAGGAGGASELADGGAGGAG
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GNGGWLLSNGGVGGAGGAGADAVGPPFGIPAGSGGNGGAGGAGGVFFGNG
MUL_0212|M.ulcerans_Agy99 GNGGWLLSNGGVGGAGGAGADAVGPPFGIPAGSGSGGGAGGAGGVFFGNG
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GAGGAGGTGGDGGGIGGAGGAAGNGVLIGNGGNGGIGGIGLTPGADGIGG
MUL_0212|M.ulcerans_Agy99 GAGGAGGTGGDGGGTGGAGGAAGNGVLIGNGGNGGIG-------------
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M TSGLVLGLDGFNAPASTSPLHTLQQQALNAINAPVEAATGRPLIGNGTPG
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M AAGSGADGTAGGWLLGDGGAGGSSTAGSGLDGGTGGAAGLWGTGGTGGAG
MUL_0212|M.ulcerans_Agy99 -----------------------------------GAAGLWGTGGTGGSG
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GSGGTDSISGIAGGDGGAGGAGGWLSGTGGAGGSGGAGGDGGVLGSGDGG
MUL_0212|M.ulcerans_Agy99 GSG-----------------------------------------------
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M AGGAGGSGGAGGLLGAGGTGGTGAIGGFSGLLASGDGGAGGAGGAGGAGG
MUL_0212|M.ulcerans_Agy99 --------------------GTGATGGFSGLLASGDGGAGGAGGAGGAGG
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M LLGGLVGAGGGDGGAGGTGGFHGDAVTGTAGAGGTGGAGGDAGLLGGPGG
MUL_0212|M.ulcerans_Agy99 LLDGLVGAGGGDGGAG----------------------------------
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M AGGTGGTGGPNIDAGGVLGAPGNSGAGGAGGNAGTLFGSGGVGGDGGSGH
MUL_0212|M.ulcerans_Agy99 ------------------------------GNAGTLFGSGGVGGDGGSGH
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GNGGDGGGGGNAGLLFSDAGGGGFGGFGLAGGGGTGGSGGDAGWLGSGGA
MUL_0212|M.ulcerans_Agy99 GNGGDGGGGGNAGLLFSDAGGGGFGGFGLAGGGGTGGSGGDAGWLGSGGA
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GGAGGISVNGDAGAGGAGGTSGQLLGDGGAGGAGGEAELAAGGAGGSGGV
MUL_0212|M.ulcerans_Agy99 GGAGGISVNGDAGAGGAGGTSGQLLGDGGAGGAGGEAELAAGGAGGSGGV
MAV_2923|M.avium_104 --------------------------------------------------
Rv0335c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0342c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4398|M.marinum_M GGDAVLIGAGGNGGNGGPGTAKGDPGSGGAGGPLGVDGLNGLS
MUL_0212|M.ulcerans_Agy99 GGDAVLIGAGGNGGNGGPGTAKGDPGSGGAGGLLGVDGLNGLS
MAV_2923|M.avium_104 -------------------------------------------
Rv0335c|M.tuberculosis_H37Rv -------------------------------------------
Mb0342c|M.bovis_AF2122/97 -------------------------------------------