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SLAVTMFKRARAEIFDRNREVGISNVTTAASLVTFPVLAGILGGVVPSVRTPSAAMVSGVQHFAAGIVMA AVAGEVLPDLRSRGPLWLIVVGFSAGVAVLVALRRFDGHGEHQDGDDVGELPVGFLTVVAVDLFIDGLLV ATGATVSSRTAIIITIALTVEVLFLGLAVALRLAGSGMPRIRAAATTSALSLVIAVGGVSGAVALGRAGN TVLTLVLAFAAGALLWLVVEELLVEAHETPERPWMAVMFFAGFLILYGLGVME*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0318c | - | - | 100% (264) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0326c | - | 1e-142 | 99.62% (264) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_4980 | - | 4e-05 | 23.65% (203) | zinc/iron permease |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0595 | - | 1e-97 | 75.10% (249) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5407 | - | 5e-07 | 28.70% (230) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0554 | - | 7e-99 | 75.90% (249) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0318c|M.tuberculosis_H37Rv MSLAVTMFKRARAEIFDRNREVGISNVTTAASLVTFPVLAGILGGVVPSV
Mb0326c|M.bovis_AF2122/97 MSLAVTMFKRARAEIFDRNREVGISNVTTAASLVTFPVLAGILGGVVPSV
MMAR_0595|M.marinum_M ------MFVSIGPGRF------GVSTLTTAAALVAFPVIAGIIGGAVAVV
MUL_0554|M.ulcerans_Agy99 ------MFVSIGPGRF------GVSTLTTAAALVAFPVIAGIIGGAVAVV
Mflv_4980|M.gilvum_PYR-GCK ------MLLWIVAAGL------AMSALALVGSLALL-----IPDRLFTRV
MSMEG_5407|M.smegmatis_MC2_155 --------------------------MLTALLWGLVAASSLLVGAVAGTV
: . . : . *
Rv0318c|M.tuberculosis_H37Rv RTPSAAMVSGVQHFAAGIVMAAVAGEVLPDLRSRGPLWLIVVGFSAGVAV
Mb0326c|M.bovis_AF2122/97 RTPSAAMVSGVQHFAAGIVMAAVAGEVLPDLRSRGPLWLIVVGFSAGVAV
MMAR_0595|M.marinum_M RTPSTALVSGVQHFAAGVVMAAVATEVLPDLRARGPLWLIILGFSAGVAL
MUL_0554|M.ulcerans_Agy99 RTPSAALVSGVQHFAAGVVMAAVATEVLPDLRARGPLWLIILGFSAGVAL
Mflv_4980|M.gilvum_PYR-GCK VLPLVALAAGALLGGAMFHMLPEAIEIVGDSTT------VFAWCAAGIVS
MSMEG_5407|M.smegmatis_MC2_155 RDWNERLVGLVLGFGAGALISSISFELAEEGVRVSGALAVALGLAIGAVV
:.. . .* : . : *: : : : * .
Rv0318c|M.tuberculosis_H37Rv LVALRRFDGHG---EHQDG-DDV---GELPVGFLTVVAVDLF--IDGLLV
Mb0326c|M.bovis_AF2122/97 LVALRRFDGHG---EHQDG-DDV---GELPVGFLTVVAVDLF--IDGLLV
MMAR_0595|M.marinum_M LAGFRQFEDHGPHGEDEDGHDDVRAGGQVPVGFLAVVAVDLF--IDGLLV
MUL_0554|M.ulcerans_Agy99 LVGFRQFEDHGPHGEDEDGHDDVRAGGQVPVGFLAVVAVDLF--IDGLLV
Mflv_4980|M.gilvum_PYR-GCK FHVLEQFLNWHHCHRPVSR--------HRPLGYLILVADGLHNLIGGLAV
MSMEG_5407|M.smegmatis_MC2_155 FYVADKTVDRMG--RTGGG-----------AGLPLLLGALLDGIPEQAVL
: : . . . * ::. * :
Rv0318c|M.tuberculosis_H37Rv ATGATVSSRTAIIITIALTVEVLFLGLAVALRLAGSGMPRIRAAATTSAL
Mb0326c|M.bovis_AF2122/97 ATGATVSSRTAIIITIALTVEVLFLGLAVALRLAGSGMPRIRAAATTSAL
MMAR_0595|M.marinum_M ATGATVSRRTAIIITIALTVEVLFLGVSVALRLTRSGVPKARAAALTGGV
MUL_0554|M.ulcerans_Agy99 ATGATVSRRTAIIITIALTVEVLFLGVSVALRLTRSGVPKARAAALTGGV
Mflv_4980|M.gilvum_PYR-GCK GSAFVVDIKLGIVTWLVAAAHEIPQELGDFGILVHSGWTPSRALFYNVVS
MSMEG_5407|M.smegmatis_MC2_155 GIGIAGGAGVSMALLVAIFVSNLPESIGSASDMRSAGHPVRTILGGWAAI
. . . . .: :. . : :. : :* .
Rv0318c|M.tuberculosis_H37Rv SLVIAVGGVSGAVALGRAGNTVLTLVLAFAAGALLWLVVEELLVEAHET-
Mb0326c|M.bovis_AF2122/97 SLVIAVGGVSGAVALGRAGNTVLTLVLAFAAAALLWLVVEELLVEAHET-
MMAR_0595|M.marinum_M SLATAVGGVLGALVLANAGGTVLTLVLAFAAAALLWLVVEELLVEAHEG-
MUL_0554|M.ulcerans_Agy99 SLATAVGGVPGALVLANAGGTVLTLVLAFAAAALLWLVVEELLVEAHEG-
Mflv_4980|M.gilvum_PYR-GCK ALTFLVG---ALLAYAFAGRLDVEVLVPFAAGNFIYIALADLLPEIATTP
MSMEG_5407|M.smegmatis_MC2_155 SALCAVATVGGYQLQKVAGAALQGGINGFAAGALLVMLVGSMIPEATQK-
: *. . ** : ***. :: : : .:: *
Rv0318c|M.tuberculosis_H37Rv --PERPWMAVMFFAGFLILYGLGVME
Mb0326c|M.bovis_AF2122/97 --PERPWMAVMFFAGFLILYGLGVME
MMAR_0595|M.marinum_M --EERAWMAIMFFAGFLILYSLGVME
MUL_0554|M.ulcerans_Agy99 --EERAWMAIMFFAGFLILYSLGVME
Mflv_4980|M.gilvum_PYR-GCK ALRDKLFYSTTFVIGLMLLWAVAQSV
MSMEG_5407|M.smegmatis_MC2_155 ---ARENAGLAAVLGFAVAAGLSLAT
: . . *: : .:.