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SGTFTADAIGPPVPIPDVPGADAGAEGLPSRSVLSARQRILVESSAIADVALRTAVASVLSATVTPAVVA NALRHVNEGSERSNLNFYAELAAAHDPAKSFPAPTELPKVTSRPASPLTEWVARGTVDNIAFASGFRAIN PTMRQRWSALTANNIVHAQHWRHRDGPRPTLCVIHGFMGSSYLLNGLFFSLPWYYRSGYDVLLYTLPFHG QRAEKFSPFSGFGYFTSGLSGFAEAMAQAVYDFRSIVDYLRHIGVDRIALTGISLGGYTSALLASVESRL EAVIPNCPVVMPAKLFDEWFPANKLVKLGLRLTNISRDELIAGLAYHGPLNYRPLLPKDRRMIITGLGDR MAPPEHAVTLWKQWDRCALHWFPGSHLLHVSQLDYLRRMTVFLQGLMFD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0293c | - | - | 100% (400) | hypothetical protein Rv0293c |
| M. tuberculosis H37Rv | Rv2627c | - | 4e-24 | 30.54% (298) | hypothetical protein Rv2627c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0301c | - | 0.0 | 100.00% (400) | hypothetical protein Mb0301c |
| M. gilvum PYR-GCK | Mflv_0317 | - | 6e-70 | 63.40% (194) | hypothetical protein Mflv_0317 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4327 | - | 1e-119 | 54.64% (366) | hypothetical protein MAB_4327 |
| M. marinum M | MMAR_0552 | - | 0.0 | 79.20% (399) | hypothetical protein MMAR_0552 |
| M. avium 104 | MAV_4861 | - | 0.0 | 76.65% (394) | hypothetical protein MAV_4861 |
| M. smegmatis MC2 155 | MSMEG_0625 | - | 1e-153 | 64.05% (395) | hypothetical protein MSMEG_0625 |
| M. thermoresistible (build 8) | TH_1308 | - | 1e-153 | 66.41% (390) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1215 | - | 0.0 | 78.45% (399) | hypothetical protein MUL_1215 |
| M. vanbaalenii PYR-1 | Mvan_0423 | - | 1e-157 | 65.73% (391) | hypothetical protein Mvan_0423 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0293c|M.tuberculosis_H37Rv ------MSGTFTADAIGPPVPIPDVPGADA--GAEGLPSRSVLSARQRIL
Mb0301c|M.bovis_AF2122/97 ------MSGTFTADAIGPPVPIPDVPGADA--GAEGLPSRSVLSARQRIL
MMAR_0552|M.marinum_M MSEISETSGTSETDPIDPPVPIPDVPGGEA--GAEGLPPLSALSLRQRLV
MUL_1215|M.ulcerans_Agy99 MSEISETSGTSETDPIDPPVPIPDVPGGEA--GAEGLPPLSALSLRQRLV
MAV_4861|M.avium_104 --------MAPDLDPFDPPIPVPDVPGADVPPGAGGLPPTSALSPRQRMV
MSMEG_0625|M.smegmatis_MC2_155 -------MEPSSVDPVDPPIPIPDVPGADA--TSRGLPRRIDLTLRQKAI
TH_1308|M.thermoresistible__bu ------VGDSQSTAPVDPSFPVPDVPGADA--GAGGLPRRADLTLAQRIT
Mflv_0317|M.gilvum_PYR-GCK ----MRDVEPDSVPDEVLPLPVPDVRGADA--TARGLPRRVDLTLRQRLI
Mvan_0423|M.vanbaalenii_PYR-1 ----MTESHAPVDP----PIPVPDVPGADA--TARGLPRRQDLALRQRLI
MAB_4327|M.abscessus_ATCC_1997 ------MTAELSEHIEQPRITPRPAPTARP-----QLPRPGDLTLRERAM
.. . . ** *: ::
Rv0293c|M.tuberculosis_H37Rv VESSAIADVALRTAVASVLSATVTPAVVANALRHVNEGSERSNLNFYAEL
Mb0301c|M.bovis_AF2122/97 VESSAIADVALRTAVASVLSATVTPAVVANALRHVNEGSERSNLNFYAEL
MMAR_0552|M.marinum_M VESSAVGDIALRTYASSLLSTTVAPAVVAHALRRLDSGGERANLNFYAEL
MUL_1215|M.ulcerans_Agy99 VESSAVGDIALRTYASSLLSTTVAPAVVAHALRRLDSGGERANLNFYAEL
MAV_4861|M.avium_104 VEASALGDLALRTWVASLLSTTVAPFVVANALRHADAATERANLEFYAEL
MSMEG_0625|M.smegmatis_MC2_155 VDASAAADIALRTGVASVVAASMLPRTAATILRRRDSRIEHEHMRFYADL
TH_1308|M.thermoresistible__bu VDASLAADLALRTAVASLIGTTMLPPFVGALLNRDASRAERRHLRFYAEL
Mflv_0317|M.gilvum_PYR-GCK VDSSAVADLALRTSIASLLSVTMVP-TLAQALNRSAAATEQEHLRFYAEL
Mvan_0423|M.vanbaalenii_PYR-1 VDSSAVADLALRTSIASLLSATMVP-SVSKALRRSEAAAEQDHLRFYAEL
MAB_4327|M.abscessus_ATCC_1997 VETSALTDIALRTVGALSVMGVVAP---SLVIDREFVARERDNLAFYGEL
*::* *:**** : : : * . : : *: :: **.:*
Rv0293c|M.tuberculosis_H37Rv AAAHDPAKSFPAPTELPKVTSRPASPLTEWVARGTVDNIAFASGFRAINP
Mb0301c|M.bovis_AF2122/97 AAAHDPAKSFPAPTELPKVTSRPASPLTEWVARGTVDNIAFASGFRAINP
MMAR_0552|M.marinum_M AAEQDPRKSFPAPTELPRISARPASPLAEWIARGSVDDISFTSGFRAINP
MUL_1215|M.ulcerans_Agy99 AAEQDPRKSFPAPTELPRISARPASPLAEWIARGSVDDISFTSGFRAKNP
MAV_4861|M.avium_104 GAAADPDRSFPPPTEPPRVTSRRASPLAEWVARGTVDNLAFDSSFTAVNP
MSMEG_0625|M.smegmatis_MC2_155 AEAKDPERSFPRPTEPPRVSSRPANPVAEWVAHGRVENIRFQSSFRAVNP
TH_1308|M.thermoresistible__bu AEQRDPARAFPAPTTVPRVTTRPANPVAEFVARGHVHNIRFDSDFEAINP
Mflv_0317|M.gilvum_PYR-GCK AAAQDPQLSFPAPQSPPRVSSRAANPVAEWVAHGKVRNIRFESGFRAVNP
Mvan_0423|M.vanbaalenii_PYR-1 AAARDPQVSFPAPQSPPRVSSRPANPVAEWIARGNVRNIRFDSSFRAVNP
MAB_4327|M.abscessus_ATCC_1997 AAMGDADLSFPEPEITPVVFSRPAGRVAQALAKATVENLDFESPYQTRNP
. *. :** * * : :* *. ::: :*:. * :: * * : : **
Rv0293c|M.tuberculosis_H37Rv TMRQRWSALTANNIVHAQHWRHRDGPRPTLCVIHGFMGSSYLLNGLFFSL
Mb0301c|M.bovis_AF2122/97 TMRQRWSALTANNIVHAQHWRHRDGPRPTLCVIHGFMGSSYLLNGLFFSL
MMAR_0552|M.marinum_M NMRQHWSALTSNNVVRAQHWRHDDGPRPTLCVIHGFMGSSYLLNGLFFSL
MUL_1215|M.ulcerans_Agy99 NMRQHWSALTSNNVVRAQHWRHDDGPRPTLCVIHGFMGSSYLLNGLFFSL
MAV_4861|M.avium_104 AMRARWSGWGRNNVVRAQHWRHDDGPRPTLCVIHGFLGSSYLANGRFFSL
MSMEG_0625|M.smegmatis_MC2_155 ALRERCRGHVRNNIVRAQHWRHNDGPHPTLCVIHGFMGSPYLANGLFLSL
TH_1308|M.thermoresistible__bu ELRDRCRGYRRNNVVRAQHWRHSDGPRPTLCVIHGFMGSAYLANGLFLSL
Mflv_0317|M.gilvum_PYR-GCK ALRDHRAGFARNNIVHAQHWRHDDGPRPTLCLIHGFMGSAYLFNGLFFSL
Mvan_0423|M.vanbaalenii_PYR-1 ALRDQCAGFVRNNVVHAQHWRHDDGPRPTLCLIHGFMGSAYLFNGLFFSL
MAB_4327|M.abscessus_ATCC_1997 ALRDYWKRFPHNSVARAQHWRHDDGPRPTLCVIHGFFGSPYLLNGAFFAL
:* *.:.:****** ***:****:****:**.** ** *::*
Rv0293c|M.tuberculosis_H37Rv PWYYRSGYDVLLYTLPFHGQRAEKFSPFSGFGYFTSGLSGFAEAMAQAVY
Mb0301c|M.bovis_AF2122/97 PWYYRSGYDVLLYTLPFHGQRAEKFSPFSGFGYFTSGLSGFAEAMAQAVY
MMAR_0552|M.marinum_M PWYYRSGYDVLLYTLPFHGKRAERFSPFSGFGFFASGLSGFAESMAQAVY
MUL_1215|M.ulcerans_Agy99 PWYYRSGYDVLLYTLPFHGKRAERFSPFSGFGFFASGLSGFAESMAQAVY
MAV_4861|M.avium_104 PWYYRAGYDVLMYTLPFHGKRAERFSPFSGFGYFAGGLSGFAEAMAQAVH
MSMEG_0625|M.smegmatis_MC2_155 PWFYRAGYDVLLYTLPFHGLRAERFSPFSGYGYFANGLAGFAEAMAQAVH
TH_1308|M.thermoresistible__bu PWFYRSGYDVLLYTLPFHGRRAERNSPFSGYGFFAHGLAGFAEAMAQAVH
Mflv_0317|M.gilvum_PYR-GCK PWFYRCGYDVVLYTR--QGPSADHRRPR----------------------
Mvan_0423|M.vanbaalenii_PYR-1 PWFYRCGYDVMLYTLPFHGRRAEKYSPFSGHGYFAHGMAGFAEAMAQAVH
MAB_4327|M.abscessus_ATCC_1997 PWFFRNGYDVLLYTLPFHGRRAEKYSPFSGAGYFSHGFTGFSESMCQAVH
**::* ****::** :* *:: *
Rv0293c|M.tuberculosis_H37Rv DFRSIVDYLRHIGVDRIALTGISLGGYTSALLASVESRLEAVIPNCPVVM
Mb0301c|M.bovis_AF2122/97 DFRSIVDYLRHIGVDRIALTGISLGGYTSALLASVESRLEAVIPNCPVVM
MMAR_0552|M.marinum_M DFRSIVDYLHHTGVTRIALTGISLGGYTSALVSSVENRLEAVIPNCPVVT
MUL_1215|M.ulcerans_Agy99 DFRSIVDYLHHTGVTRIALTGISLGGYTSALVSSVENRLEAVIPNCPVVT
MAV_4861|M.avium_104 DFRSLIDYLRHTGVERIALTGISLGGYTSALVASVDDRLEAVIPNCPVVT
MSMEG_0625|M.smegmatis_MC2_155 DFRSVMDHLEFTGVDRIALTGISLGGFTSALLASVDHRIQAVIPNVPVVT
TH_1308|M.thermoresistible__bu DFRSLMNYLEFTGVDRIALTGISLGGYTSALLAAVDDRIQAVIPNVPVVT
Mflv_0317|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0423|M.vanbaalenii_PYR-1 DFRSIIDYLEFTGVDRIALTGMSLGGYTSALIASVDDRVQAVIPNVPVVT
MAB_4327|M.abscessus_ATCC_1997 DFRIFVNYLRGTGVEKIGLTGLSLGGYTTGLISTVERRIDVTIPNVPVVD
Rv0293c|M.tuberculosis_H37Rv PAKLFDEWFPANKLVKLGLRLTNISRDELIAGLAYHGPLNYRPLLPKDRR
Mb0301c|M.bovis_AF2122/97 PAKLFDEWFPANKLVKLGLRLTNISRDELIAGLAYHGPLNYRPLLPKDRR
MMAR_0552|M.marinum_M PAKLFEQWFPASKLVRLGLCLSSISRGELDAGLAFHSPLNYRPQLPKHRR
MUL_1215|M.ulcerans_Agy99 PAELFEQWFPASKLVRLGLCLSSISRGELDAGLAFHSPLNYRPQLPKHRR
MAV_4861|M.avium_104 PATLFDEWFPANKLVGLGLRSSDISRAQLAAGLAYHCPLTYRPLLAKDRR
MSMEG_0625|M.smegmatis_MC2_155 PDRTVDEWFPANMLVALERHIAHTDPELTEAAARYASPLHYQPLVAKERR
TH_1308|M.thermoresistible__bu PQAAFDDWFPANKLVALTNAVTAIDRELAGAAGMYHSPLNYRPLVPKERR
Mflv_0317|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0423|M.vanbaalenii_PYR-1 PDRTVDEWFPANKVVALRDWIAGTDTELVGAATMYSSPLNYRPLIPKDRR
MAB_4327|M.abscessus_ATCC_1997 VKSLLHSWIPAEPTIKLAARLGHLDQGRLDGALSYSSPLTYQPVVPREQR
Rv0293c|M.tuberculosis_H37Rv MIITGLGDRMAPPEHAVTLWKQWDRCALHWFPGSHLLHVSQLDYLRRMTV
Mb0301c|M.bovis_AF2122/97 MIITGLGDRMAPPEHAVTLWKQWDRCALHWFPGSHLLHVSQLDYLRRMTV
MMAR_0552|M.marinum_M MIIAGLGDRMAPPDHAETLWEHWDRCALHWFPGSHVLHVSQLDYLRRMTA
MUL_1215|M.ulcerans_Agy99 MIIAGLGDRMAPPDHAEPLWEHWDRCALHWFPGSHVLHVSQLDYLRRMTA
MAV_4861|M.avium_104 MIITGLGDRMAPPEHAVKLWQHWDHCALHWFPGSHVLHISQLDYLRRMTA
MSMEG_0625|M.smegmatis_MC2_155 LIITGLGDRLAPPQQAELLWEHWDRCAFHWFPGNHLLHVSQPDYLRRMTR
TH_1308|M.thermoresistible__bu LIITGLGDRFAPPQQAELLWKHWDRCAFHWFPGNHLLHVSQPDYLRRMTR
Mflv_0317|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0423|M.vanbaalenii_PYR-1 LIIAGLGDRLAPPEQAEILWRHWDHCAFHWFPGNHVLHVSQPDYLRRMTR
MAB_4327|M.abscessus_ATCC_1997 LIITGLGDRLAPPEQSEMLWEHWDRCALHWFPGNHILHVNQGDYLRRMTE
Rv0293c|M.tuberculosis_H37Rv FLQGLMFD
Mb0301c|M.bovis_AF2122/97 FLQGLMFD
MMAR_0552|M.marinum_M FLGDFMFD
MUL_1215|M.ulcerans_Agy99 FLGDFMFD
MAV_4861|M.avium_104 FLQQVMF-
MSMEG_0625|M.smegmatis_MC2_155 FLRGFMFD
TH_1308|M.thermoresistible__bu FLGDVMFG
Mflv_0317|M.gilvum_PYR-GCK --------
Mvan_0423|M.vanbaalenii_PYR-1 FMGAFMFD
MAB_4327|M.abscessus_ATCC_1997 FLDRHLNV