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M. thermoresistible (build 8) TH_1308 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 2486229 - 2487431
length: 401

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1308-100% (401)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1422-4e-2531.92% (307) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0301c-1e-15366.41% (390) hypothetical protein Mb0301c
M. gilvum PYR-GCKMflv_0317-2e-7368.23% (192) hypothetical protein Mflv_0317
M. tuberculosis H37RvRv0293c-1e-15366.41% (390) hypothetical protein Rv0293c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4327-1e-12155.74% (366) hypothetical protein MAB_4327
M. marinum MMMAR_0552-1e-15464.39% (396) hypothetical protein MMAR_0552
M. avium 104MAV_4861-1e-15466.67% (393) hypothetical protein MAV_4861
M. smegmatis MC2 155MSMEG_0625-1e-17774.56% (397) hypothetical protein MSMEG_0625
M. ulcerans Agy99MUL_1215-1e-15464.14% (396) hypothetical protein MUL_1215
M. vanbaalenii PYR-1Mvan_0423-1e-17973.99% (396) hypothetical protein Mvan_0423

CLUSTAL 2.0.9 multiple sequence alignment


Mb0301c|M.bovis_AF2122/97           ------MSGTFTADAIGPPVPIPDVPGADA--GAEGLPSRSVLSARQRIL
Rv0293c|M.tuberculosis_H37Rv        ------MSGTFTADAIGPPVPIPDVPGADA--GAEGLPSRSVLSARQRIL
MMAR_0552|M.marinum_M               MSEISETSGTSETDPIDPPVPIPDVPGGEA--GAEGLPPLSALSLRQRLV
MUL_1215|M.ulcerans_Agy99           MSEISETSGTSETDPIDPPVPIPDVPGGEA--GAEGLPPLSALSLRQRLV
MAV_4861|M.avium_104                --------MAPDLDPFDPPIPVPDVPGADVPPGAGGLPPTSALSPRQRMV
TH_1308|M.thermoresistible__bu      ------VGDSQSTAPVDPSFPVPDVPGADA--GAGGLPRRADLTLAQRIT
MSMEG_0625|M.smegmatis_MC2_155      -------MEPSSVDPVDPPIPIPDVPGADA--TSRGLPRRIDLTLRQKAI
Mflv_0317|M.gilvum_PYR-GCK          ----MRDVEPDSVPDEVLPLPVPDVRGADA--TARGLPRRVDLTLRQRLI
Mvan_0423|M.vanbaalenii_PYR-1       ----MTESHAPVDP----PIPVPDVPGADA--TARGLPRRQDLALRQRLI
MAB_4327|M.abscessus_ATCC_1997      ------MTAELSEHIEQPRITPRPAPTARP-----QLPRPGDLTLRERAM
                                                       ..   .  .        **    *:  ::  

Mb0301c|M.bovis_AF2122/97           VESSAIADVALRTAVASVLSATVTPAVVANALRHVNEGSERSNLNFYAEL
Rv0293c|M.tuberculosis_H37Rv        VESSAIADVALRTAVASVLSATVTPAVVANALRHVNEGSERSNLNFYAEL
MMAR_0552|M.marinum_M               VESSAVGDIALRTYASSLLSTTVAPAVVAHALRRLDSGGERANLNFYAEL
MUL_1215|M.ulcerans_Agy99           VESSAVGDIALRTYASSLLSTTVAPAVVAHALRRLDSGGERANLNFYAEL
MAV_4861|M.avium_104                VEASALGDLALRTWVASLLSTTVAPFVVANALRHADAATERANLEFYAEL
TH_1308|M.thermoresistible__bu      VDASLAADLALRTAVASLIGTTMLPPFVGALLNRDASRAERRHLRFYAEL
MSMEG_0625|M.smegmatis_MC2_155      VDASAAADIALRTGVASVVAASMLPRTAATILRRRDSRIEHEHMRFYADL
Mflv_0317|M.gilvum_PYR-GCK          VDSSAVADLALRTSIASLLSVTMVP-TLAQALNRSAAATEQEHLRFYAEL
Mvan_0423|M.vanbaalenii_PYR-1       VDSSAVADLALRTSIASLLSATMVP-SVSKALRRSEAAAEQDHLRFYAEL
MAB_4327|M.abscessus_ATCC_1997      VETSALTDIALRTVGALSVMGVVAP---SLVIDREFVARERDNLAFYGEL
                                    *::*   *:****  :  :   : *   .  : :     *: :: **.:*

Mb0301c|M.bovis_AF2122/97           AAAHDPAKSFPAPTELPKVTSRPASPLTEWVARGTVDNIAFASGFRAINP
Rv0293c|M.tuberculosis_H37Rv        AAAHDPAKSFPAPTELPKVTSRPASPLTEWVARGTVDNIAFASGFRAINP
MMAR_0552|M.marinum_M               AAEQDPRKSFPAPTELPRISARPASPLAEWIARGSVDDISFTSGFRAINP
MUL_1215|M.ulcerans_Agy99           AAEQDPRKSFPAPTELPRISARPASPLAEWIARGSVDDISFTSGFRAKNP
MAV_4861|M.avium_104                GAAADPDRSFPPPTEPPRVTSRRASPLAEWVARGTVDNLAFDSSFTAVNP
TH_1308|M.thermoresistible__bu      AEQRDPARAFPAPTTVPRVTTRPANPVAEFVARGHVHNIRFDSDFEAINP
MSMEG_0625|M.smegmatis_MC2_155      AEAKDPERSFPRPTEPPRVSSRPANPVAEWVAHGRVENIRFQSSFRAVNP
Mflv_0317|M.gilvum_PYR-GCK          AAAQDPQLSFPAPQSPPRVSSRAANPVAEWVAHGKVRNIRFESGFRAVNP
Mvan_0423|M.vanbaalenii_PYR-1       AAARDPQVSFPAPQSPPRVSSRPANPVAEWIARGNVRNIRFDSSFRAVNP
MAB_4327|M.abscessus_ATCC_1997      AAMGDADLSFPEPEITPVVFSRPAGRVAQALAKATVENLDFESPYQTRNP
                                    .   *.  :** *   * : :* *. ::: :*:. * :: * * : : **

Mb0301c|M.bovis_AF2122/97           TMRQRWSALTANNIVHAQHWRHRDGPRPTLCVIHGFMGSSYLLNGLFFSL
Rv0293c|M.tuberculosis_H37Rv        TMRQRWSALTANNIVHAQHWRHRDGPRPTLCVIHGFMGSSYLLNGLFFSL
MMAR_0552|M.marinum_M               NMRQHWSALTSNNVVRAQHWRHDDGPRPTLCVIHGFMGSSYLLNGLFFSL
MUL_1215|M.ulcerans_Agy99           NMRQHWSALTSNNVVRAQHWRHDDGPRPTLCVIHGFMGSSYLLNGLFFSL
MAV_4861|M.avium_104                AMRARWSGWGRNNVVRAQHWRHDDGPRPTLCVIHGFLGSSYLANGRFFSL
TH_1308|M.thermoresistible__bu      ELRDRCRGYRRNNVVRAQHWRHSDGPRPTLCVIHGFMGSAYLANGLFLSL
MSMEG_0625|M.smegmatis_MC2_155      ALRERCRGHVRNNIVRAQHWRHNDGPHPTLCVIHGFMGSPYLANGLFLSL
Mflv_0317|M.gilvum_PYR-GCK          ALRDHRAGFARNNIVHAQHWRHDDGPRPTLCLIHGFMGSAYLFNGLFFSL
Mvan_0423|M.vanbaalenii_PYR-1       ALRDQCAGFVRNNVVHAQHWRHDDGPRPTLCLIHGFMGSAYLFNGLFFSL
MAB_4327|M.abscessus_ATCC_1997      ALRDYWKRFPHNSVARAQHWRHDDGPRPTLCVIHGFFGSPYLLNGAFFAL
                                     :*        *.:.:****** ***:****:****:**.** ** *::*

Mb0301c|M.bovis_AF2122/97           PWYYRSGYDVLLYTLPFHGQRAEKFSPFSGFGYFTSGLSGFAEAMAQAVY
Rv0293c|M.tuberculosis_H37Rv        PWYYRSGYDVLLYTLPFHGQRAEKFSPFSGFGYFTSGLSGFAEAMAQAVY
MMAR_0552|M.marinum_M               PWYYRSGYDVLLYTLPFHGKRAERFSPFSGFGFFASGLSGFAESMAQAVY
MUL_1215|M.ulcerans_Agy99           PWYYRSGYDVLLYTLPFHGKRAERFSPFSGFGFFASGLSGFAESMAQAVY
MAV_4861|M.avium_104                PWYYRAGYDVLMYTLPFHGKRAERFSPFSGFGYFAGGLSGFAEAMAQAVH
TH_1308|M.thermoresistible__bu      PWFYRSGYDVLLYTLPFHGRRAERNSPFSGYGFFAHGLAGFAEAMAQAVH
MSMEG_0625|M.smegmatis_MC2_155      PWFYRAGYDVLLYTLPFHGLRAERFSPFSGYGYFANGLAGFAEAMAQAVH
Mflv_0317|M.gilvum_PYR-GCK          PWFYRCGYDVVLYTR--QGPSADHRRPR----------------------
Mvan_0423|M.vanbaalenii_PYR-1       PWFYRCGYDVMLYTLPFHGRRAEKYSPFSGHGYFAHGMAGFAEAMAQAVH
MAB_4327|M.abscessus_ATCC_1997      PWFFRNGYDVLLYTLPFHGRRAEKYSPFSGAGYFSHGFTGFSESMCQAVH
                                    **::* ****::**   :*  *::  *                       

Mb0301c|M.bovis_AF2122/97           DFRSIVDYLRHIGVDRIALTGISLGGYTSALLASVESRLEAVIPNCPVVM
Rv0293c|M.tuberculosis_H37Rv        DFRSIVDYLRHIGVDRIALTGISLGGYTSALLASVESRLEAVIPNCPVVM
MMAR_0552|M.marinum_M               DFRSIVDYLHHTGVTRIALTGISLGGYTSALVSSVENRLEAVIPNCPVVT
MUL_1215|M.ulcerans_Agy99           DFRSIVDYLHHTGVTRIALTGISLGGYTSALVSSVENRLEAVIPNCPVVT
MAV_4861|M.avium_104                DFRSLIDYLRHTGVERIALTGISLGGYTSALVASVDDRLEAVIPNCPVVT
TH_1308|M.thermoresistible__bu      DFRSLMNYLEFTGVDRIALTGISLGGYTSALLAAVDDRIQAVIPNVPVVT
MSMEG_0625|M.smegmatis_MC2_155      DFRSVMDHLEFTGVDRIALTGISLGGFTSALLASVDHRIQAVIPNVPVVT
Mflv_0317|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0423|M.vanbaalenii_PYR-1       DFRSIIDYLEFTGVDRIALTGMSLGGYTSALIASVDDRVQAVIPNVPVVT
MAB_4327|M.abscessus_ATCC_1997      DFRIFVNYLRGTGVEKIGLTGLSLGGYTTGLISTVERRIDVTIPNVPVVD
                                                                                      

Mb0301c|M.bovis_AF2122/97           PAKLFDEWFPANKLVKLGLRLTNISRDELIAGLAYHGPLNYRPLLPKDRR
Rv0293c|M.tuberculosis_H37Rv        PAKLFDEWFPANKLVKLGLRLTNISRDELIAGLAYHGPLNYRPLLPKDRR
MMAR_0552|M.marinum_M               PAKLFEQWFPASKLVRLGLCLSSISRGELDAGLAFHSPLNYRPQLPKHRR
MUL_1215|M.ulcerans_Agy99           PAELFEQWFPASKLVRLGLCLSSISRGELDAGLAFHSPLNYRPQLPKHRR
MAV_4861|M.avium_104                PATLFDEWFPANKLVGLGLRSSDISRAQLAAGLAYHCPLTYRPLLAKDRR
TH_1308|M.thermoresistible__bu      PQAAFDDWFPANKLVALTNAVTAIDRELAGAAGMYHSPLNYRPLVPKERR
MSMEG_0625|M.smegmatis_MC2_155      PDRTVDEWFPANMLVALERHIAHTDPELTEAAARYASPLHYQPLVAKERR
Mflv_0317|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0423|M.vanbaalenii_PYR-1       PDRTVDEWFPANKVVALRDWIAGTDTELVGAATMYSSPLNYRPLIPKDRR
MAB_4327|M.abscessus_ATCC_1997      VKSLLHSWIPAEPTIKLAARLGHLDQGRLDGALSYSSPLTYQPVVPREQR
                                                                                      

Mb0301c|M.bovis_AF2122/97           MIITGLGDRMAPPEHAVTLWKQWDRCALHWFPGSHLLHVSQLDYLRRMTV
Rv0293c|M.tuberculosis_H37Rv        MIITGLGDRMAPPEHAVTLWKQWDRCALHWFPGSHLLHVSQLDYLRRMTV
MMAR_0552|M.marinum_M               MIIAGLGDRMAPPDHAETLWEHWDRCALHWFPGSHVLHVSQLDYLRRMTA
MUL_1215|M.ulcerans_Agy99           MIIAGLGDRMAPPDHAEPLWEHWDRCALHWFPGSHVLHVSQLDYLRRMTA
MAV_4861|M.avium_104                MIITGLGDRMAPPEHAVKLWQHWDHCALHWFPGSHVLHISQLDYLRRMTA
TH_1308|M.thermoresistible__bu      LIITGLGDRFAPPQQAELLWKHWDRCAFHWFPGNHLLHVSQPDYLRRMTR
MSMEG_0625|M.smegmatis_MC2_155      LIITGLGDRLAPPQQAELLWEHWDRCAFHWFPGNHLLHVSQPDYLRRMTR
Mflv_0317|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0423|M.vanbaalenii_PYR-1       LIIAGLGDRLAPPEQAEILWRHWDHCAFHWFPGNHVLHVSQPDYLRRMTR
MAB_4327|M.abscessus_ATCC_1997      LIITGLGDRLAPPEQSEMLWEHWDRCALHWFPGNHILHVNQGDYLRRMTE
                                                                                      

Mb0301c|M.bovis_AF2122/97           FLQGLMFD
Rv0293c|M.tuberculosis_H37Rv        FLQGLMFD
MMAR_0552|M.marinum_M               FLGDFMFD
MUL_1215|M.ulcerans_Agy99           FLGDFMFD
MAV_4861|M.avium_104                FLQQVMF-
TH_1308|M.thermoresistible__bu      FLGDVMFG
MSMEG_0625|M.smegmatis_MC2_155      FLRGFMFD
Mflv_0317|M.gilvum_PYR-GCK          --------
Mvan_0423|M.vanbaalenii_PYR-1       FMGAFMFD
MAB_4327|M.abscessus_ATCC_1997      FLDRHLNV