For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
ASSASDGTHERSAFRLSPPVLSGAMGPFMHTGLYVAQSWRDYLGQQPDKLPIARPTIALAAQAFRDEIVL LGLKARRPVSNHRVFERISQEVAAGLEFYGNRRWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYRIFFDS GFTPHPGEPGSQRWLSYTANNREYALLLRHPEPRPWLVCVHGTEMGRAPLDLAVFRAWKLHDELGLNIVM PVLPMHGPRGQGLPKGAVFPGEDVLDDVHGTAQAVWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVA SLEEGLACAILGVPVADLIELLGRHCGLRHKDPRRHTVKMAEPIGRMISPLSLTPLVPMPGRFIYAGIAD RLVHPREQVTRLWEHWGKPEIVWYPGGHTGFFQSRPVRRFVQAALEQSGLLDAPRTQRDRSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2627c | - | - | 100% (413) | hypothetical protein Rv2627c |
| M. tuberculosis H37Rv | Rv0293c | - | 4e-24 | 30.54% (298) | hypothetical protein Rv0293c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2660c | - | 0.0 | 99.76% (413) | hypothetical protein Mb2660c |
| M. gilvum PYR-GCK | Mflv_4981 | - | 1e-142 | 66.19% (352) | hypothetical protein Mflv_4981 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4327 | - | 5e-24 | 33.05% (239) | hypothetical protein MAB_4327 |
| M. marinum M | MMAR_2072 | - | 0.0 | 75.30% (417) | hypothetical protein MMAR_2072 |
| M. avium 104 | MAV_1605 | - | 9e-29 | 31.88% (298) | hypothetical protein MAV_1605 |
| M. smegmatis MC2 155 | MSMEG_0625 | - | 4e-21 | 30.58% (242) | hypothetical protein MSMEG_0625 |
| M. thermoresistible (build 8) | TH_1422 | - | 1e-155 | 68.42% (380) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1215 | - | 4e-24 | 30.16% (305) | hypothetical protein MUL_1215 |
| M. vanbaalenii PYR-1 | Mvan_1418 | - | 1e-156 | 64.36% (390) | hypothetical protein Mvan_1418 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2627c|M.tuberculosis_H37Rv MASSASDGTHERSAFRLSPPVLSGAMG----PFMHTGLYVAQSWRDYLGQ
Mb2660c|M.bovis_AF2122/97 MASSASDGTHERSAFRLSPPVLSGAMG----PFMHTGLYVAQSWRDYLGQ
MMAR_2072|M.marinum_M MAKPAGDDAQESPGARQVNPIGLGGLGSVVTPFVHTGRYFAESWRDYLDQ
Mflv_4981|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1418|M.vanbaalenii_PYR-1 ------MEKCCGASFESVAPSLRDTFR----PLAKTGIYYARSWREYLAG
TH_1422|M.thermoresistible__bu ------------------------VVR----PFRRTGRYYGGLWREYLRR
MSMEG_0625|M.smegmatis_MC2_155 -----------------MEPSSVDPVD---PPIPIPDVPGADATSRGLPR
MUL_1215|M.ulcerans_Agy99 ----------MSEISETSGTSETDPID---PPVPIPDVPGGEAGAEGLPP
MAB_4327|M.abscessus_ATCC_1997 -----------------MTAELSEHIE---QPR-ITPRPAPTARPQ-LPR
MAV_1605|M.avium_104 ------------------MAKALSGLS----LARDAARELAMLVPRTVAG
Rv2627c|M.tuberculosis_H37Rv QPD---KLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFER-ISQE
Mb2660c|M.bovis_AF2122/97 QPD---KLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFER-ISQE
MMAR_2072|M.marinum_M DSD---GLPIARPTIALAAQAFRDEIVLMGLKARRPVSDPHVFER-IDDE
Mflv_4981|M.gilvum_PYR-GCK -------MPIARPTVGLAVEALRDEVVLFGLRARRPLSDPASFER-IHDE
Mvan_1418|M.vanbaalenii_PYR-1 ETP---QLPIARPTVALAAEALRDEVVLLGLRARRPLSDPEAFAR-IHDE
TH_1422|M.thermoresistible__bu TPQE-EELPLTRPTLALAAEAFRDEVVLLGLRTRRPVSDVRAFER-ITAE
MSMEG_0625|M.smegmatis_MC2_155 RIDLTLRQKAIVDASAAADIALRTGVASVVAASMLPRTAATILRRRDSRI
MUL_1215|M.ulcerans_Agy99 LSALSLRQRLVVESSAVGDIALRTYASSLLSTTVAPAVVAHALRRLDSGG
MAB_4327|M.abscessus_ATCC_1997 PGDLTLRERAMVETSALTDIALRTVGALSVMGVVAP---SLVIDREFVAR
MAV_1605|M.avium_104 LQESTGWAPLSPRGARQFGEVMLDELVLSAFSLLGGSPAALRPVD-ACAA
.:
Rv2627c|M.tuberculosis_H37Rv VAAGLEFYGNRRWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYR-----I
Mb2660c|M.bovis_AF2122/97 VAAGLEFYGNRGWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYR-----I
MMAR_2072|M.marinum_M VALALQFYGDQGWLQRPRTFFADPPPPSEVTVRKVKGRKRSFYR-----M
Mflv_4981|M.gilvum_PYR-GCK VVAALDFYGGRGCLADPARFFTTPDALADVEVTPVRRRNHTYAR-----L
Mvan_1418|M.vanbaalenii_PYR-1 VVAALKFYGRRGWLDDPEGFFRPPAPLTDVEVTPVRRRNHTYAR-----L
TH_1422|M.thermoresistible__bu VREALEFFGSRGCLDDPEKFFTPPPALDEVTVLPREGRRRDHDR-----I
MSMEG_0625|M.smegmatis_MC2_155 EHEHMRFYADLAEAKDPERSFPRPTEPPRVSSRPANPVAEWVAHGRVENI
MUL_1215|M.ulcerans_Agy99 ERANLNFYAELAAEQDPRKSFPAPTELPRISARPASPLAEWIARGSVDDI
MAB_4327|M.abscessus_ATCC_1997 ERDNLAFYGELAAMGDADLSFPEPEITPVVFSRPAGRVAQALAKATVENL
MAV_1605|M.avium_104 AAEELAALG-------IDGAHAAPNPLRPTSIRRRSIAGLDYER------
: . . * :
Rv2627c|M.tuberculosis_H37Rv FFDSGFTPHPGEPGSQRWLSYTANNREYALLLRHPE-PRPWLVCVHGTEM
Mb2660c|M.bovis_AF2122/97 FFDSGFTPHPGEPGSQRWLSYTANNREYALLLRHPE-PRPWLVCVHGTEM
MMAR_2072|M.marinum_M FFDSGYTPLPGEPGGQRWLGYTANNREYALLLRHRE-PRPWLVCVHGTEM
Mflv_4981|M.gilvum_PYR-GCK RWESGYHPLAGEPGGDRWMTYTANRRGYALMLRHPE-PRPWLMCIHGTEM
Mvan_1418|M.vanbaalenii_PYR-1 RWESGYRPLRGEPGGDRWATYTANRRGYGLLLRHPE-PRPWLVCIHGTEM
TH_1422|M.thermoresistible__bu RWDSGYAPLPGAPGGQRYAGYSANDRCYALLLRHAE-PRPWLIGIHGTEM
MSMEG_0625|M.smegmatis_MC2_155 RFQSSFRAV-NPALRERCRGHVRNNIVRAQHWRHNDGPHPTLCVIHG-FM
MUL_1215|M.ulcerans_Agy99 SFTSGFRAK-NPNMRQHWSALTSNNVVRAQHWRHDDGPRPTLCVIHG-FM
MAB_4327|M.abscessus_ATCC_1997 DFESPYQTR-NPALRDYWKRFPHNSVARAQHWRHDDGPRPTLCVIHG-FF
MAV_1605|M.avium_104 ---MAFEHDPALPATLVADGLGGPARAVVHLRRHRDGPRPWLVWVHGAGQ
: ** : *:* * :**
Rv2627c|M.tuberculosis_H37Rv GRAPLDLAVFRAWKLHDELGLNIVMPVLPMHGPRGQGLP--KGAVFPGED
Mb2660c|M.bovis_AF2122/97 GRAPLDLAVFRAWKLHDELGLNIVMPVLPMHGPRGQGLP--KGAVFPGED
MMAR_2072|M.marinum_M GRAPLDLALFRSWKLHRELGLNIVMPVLPMHGPRARDLP--KGAVYPGED
Mflv_4981|M.gilvum_PYR-GCK GRAALDLALFRAWYLHEELGLNVMLPVLPMHGPRGRGLP--KGAVFPGED
Mvan_1418|M.vanbaalenii_PYR-1 GRAALDLALFRAWYLHEELGLNVVLPVMPMHGPRGRQLP--KGAVFPGED
TH_1422|M.thermoresistible__bu GRAAVDLAVFRARRLHRELGLNVVLPVLPMHGPRGRGLP--KGAVFPGED
MSMEG_0625|M.smegmatis_MC2_155 GSPYLANGLFLSLPWFYRAGYDVLLYTLPFHGLRAERFSPFSGYGYFANG
MUL_1215|M.ulcerans_Agy99 GSSYLLNGLFFSLPWYYRSGYDVLLYTLPFHGKRAERFSPFSGFGFFASG
MAB_4327|M.abscessus_ATCC_1997 GSPYLLNGAFFALPWFFRNGYDVLLYTLPFHGRRAEKYSPFSGAGYFSHG
MAV_1605|M.avium_104 GG-TEDLLLSGIGRIHRELGFNIAMPVQPGHGCRRRQWP-----VYPDMD
* . . * :: : . * ** * . . : .
Rv2627c|M.tuberculosis_H37Rv VLDDVHGTAQAVWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLE
Mb2660c|M.bovis_AF2122/97 VLDDVHGTAQAVWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLE
MMAR_2072|M.marinum_M VLDNVHATAQAVWDIRRLISWIRMQEPESLIGINGLSLGGYIASLVASLE
Mflv_4981|M.gilvum_PYR-GCK VLDDIHATAHAVWDIRALLGWIRAENPGADIGVYGLSLGGFIAGLLAGLD
Mvan_1418|M.vanbaalenii_PYR-1 MLDDIHATGQAVWDIRALLGWIRAEQPGAAIGVYGLSLGGFIAALVASLD
TH_1422|M.thermoresistible__bu VLDNVHATGQAVWDVRRLISWIRAQEPDSAIGLNGISLGGFVTSLVVSLE
MSMEG_0625|M.smegmatis_MC2_155 LAGFAEAMAQAVHDFRSVMDHLEFTG-VDRIALTGISLGGFTSALLASVD
MUL_1215|M.ulcerans_Agy99 LSGFAESMAQAVYDFRSIVDYLHHTG-VTRIALTGISLGGYTSALVSSVE
MAB_4327|M.abscessus_ATCC_1997 FTGFSESMCQAVHDFRIFVNYLRGTG-VEKIGLTGLSLGGYTTGLISTVE
MAV_1605|M.avium_104 PLGNVAGMMRAVSEVRAVVRWARSQA--STLVVAGISMGSPVAALVSHLE
. . :** :.* .: . : : *:*:*. :.*: ::
Rv2627c|M.tuberculosis_H37Rv EGLACAILGVPVADLIELLGRHCGLRHKDPRRHTVKMAEP-----IGRMI
Mb2660c|M.bovis_AF2122/97 EGLACAILGVPVADLIELLGRHCGLRHKDPRRHTVKMAEP-----IGRMI
MMAR_2072|M.marinum_M DDLTCAILGVPVADLVDLLGRHSGFGRDDPRRETVALAEP-----IGHMI
Mflv_4981|M.gilvum_PYR-GCK DGLTCAVLGVPVADLIDLLSRHSGLGRDDPRRRTILLAAP-----LGRMI
Mvan_1418|M.vanbaalenii_PYR-1 DELVCAVLGVPVADLVDLLSRHSGMARDDPRRRTIELAGP-----LGQMI
TH_1422|M.thermoresistible__bu DGLTCAILGVPVADLIELLGRHAGLRRGDPRRETMELARP-----LGRMI
MSMEG_0625|M.smegmatis_MC2_155 HRIQAVIPNVPVVTPDRTVDEWFPANMLVALERHIAHTDPELTEAAARYA
MUL_1215|M.ulcerans_Agy99 NRLEAVIPNCPVVTPAELFEQWFPASKLVRLGLCLSSISRGELDAGLAFH
MAB_4327|M.abscessus_ATCC_1997 RRIDVTIPNVPVVDVKSLLHSWIPAEPTIKLAARLGHLDQGRLDGALSYS
MAV_1605|M.avium_104 RQVDAVALYTPILGLNAMIARHLQRWGPARDGFRELLQSP-VVTRLTSVI
: . *: .
Rv2627c|M.tuberculosis_H37Rv SPLSLTPLVPMPGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGH
Mb2660c|M.bovis_AF2122/97 SPLSLTPLVPMPGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGH
MMAR_2072|M.marinum_M SPLALTPLVPRAGRFIYAGVADQLVHPRRQVARLWEHWGKPDIVWYPGGH
Mflv_4981|M.gilvum_PYR-GCK SPLSLPPPVPMSGRFIYAGLADQVVHPREQVVRLWEHWGRPNIEWYHGGH
Mvan_1418|M.vanbaalenii_PYR-1 SPLSLTPRVPLSGRFIYAGLADQVVHPREQVARLWEHWGRPNIAWYRGGH
TH_1422|M.thermoresistible__bu SPLSLRPRVPPRGRFVYGGIADRVVHPREQVVRLWEHWDRPDIVWYRGGH
MSMEG_0625|M.smegmatis_MC2_155 SPLHYQPLVAKERRLIITGLGDRLAPP-QQAELLWEHWDRCAFHWFPGNH
MUL_1215|M.ulcerans_Agy99 SPLNYRPQLPKHRRMIIAGLGDRMAPP-DHAEPLWEHWDRCALHWFPGSH
MAB_4327|M.abscessus_ATCC_1997 SPLTYQPVVPREQRLIITGLGDRLAPP-EQSEMLWEHWDRCALHWFPGNH
MAV_1605|M.avium_104 DPLAVTPAPPPERRLIVGAWHDRMAMR-EPANALQDRWAG-QLYWYDGSH
.** * . *:: . *::. * ::* : *: *.*
Rv2627c|M.tuberculosis_H37Rv TGFFQSRPVRRFVQAALEQSGLLDAPRTQRDRSA---
Mb2660c|M.bovis_AF2122/97 TGFFQSRPVRRFVQAALEQSGLLDAPRTQRDRSA---
MMAR_2072|M.marinum_M TGFFRSRPVQQFVEDALQQSGLLDDPSEQRDRPA---
Mflv_4981|M.gilvum_PYR-GCK TGFFQSRPVQHFVTDALVRSGLVTGIGRPQSPDAATG
Mvan_1418|M.vanbaalenii_PYR-1 TGFFQSRPVNRFIADALARSGLLAGIDRPGMPDATTG
TH_1422|M.thermoresistible__bu TGFFQSRSVQRFVEDALAQSGLIEAPGRA--------
MSMEG_0625|M.smegmatis_MC2_155 LLHVSQPDYLRRMTRFLRGFMFD--------------
MUL_1215|M.ulcerans_Agy99 VLHVSQLDYLRRMTAFLGDFMFD--------------
MAB_4327|M.abscessus_ATCC_1997 ILHVNQGDYLRRMTEFLDRHLNV--------------
MAV_1605|M.avium_104 VGHIFSRRVQRITDRFLRDAVLA--------------
.. . : *