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M. tuberculosis H37Rv Rv0252 (nirB)

annotation: PROBABLE NITRITE REDUCTASE
coordinates: 302866 - 305427
length: 853

MPTAGSSRAPAAAREIVVVGHGMVGHRLVEAVRARDADGSLRITVLAEEGDAAYDRVGLTSYTESWDRAL
LALPGNDYAGDQRVRLLLNTRVTQIDRATKSVVTAAGQRHRYDTLVLATGSYAFVPPVPGHDLPACHVYR
TFDDLDAIRAGAQRTLDGGHTDGGVVIGGGLLGLEAANALRQFGLQTHVVEMMPRLMAQQIDEAGGALLA
RMIADLGIAVHVGTGTESIESVKHSDGSVWARVRLSDGEVIDAGVVIFAAGIRPRDELARAAGLAIGDRG
GVLTDLSCRTSDPDIYAVGEVAAIDGRCYGLVGPGYTSAEVVADRLLDGSAEFPEADLSTKLKLLGVDVA
SFGDAMGATENCLEVVINDAVKRTYAKLVLSDDATTLLGGVLVGDASSYGVLRPMVGAELPGDPLALIAP
AGSGAGAGALGVGALPDSAQICSCNNVTKGELKCAIADGCGDVPALKSCTAAGTSCGSCVPLLKQLLEAE
GVEQSKALCEHFSQSRAELFEIITATEVRTFSGLLDRFGRGKGCDICKPVVASILASTGSDHILDGEQAS
LQDSNDHFLANIQKNGSYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDLFGARVDQLPLIW
QRLVDGGMESGHAYGKAVRTVKSCVGSDWCRYGQQDSVQLAIDLELRYRGLRAPHKIKLGVSGCARECAE
ARGKDVGVIATEKGWNLYVAGNGGMTPKHAQLLASDLDKETLIRYIDRFLIYYIRTADRLQRTAPWVESL
GLDHVREVVCEDSLGLAEEFEAAMQRHVANYKCEWKGVLEDPDKLSRFVSFVNAPDAVDSTVTFTERAGR
KVPVSIGIPRVRS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0252nirB-100% (853)PROBABLE NITRITE REDUCTASE
M. tuberculosis H37RvRv1869c-4e-4036.03% (297) reductase
M. tuberculosis H37RvRv0688-1e-2730.10% (289) putative ferredoxin reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0258nirB0.0100.00% (853) nitrite reductase
M. gilvum PYR-GCKMflv_0387-0.078.80% (849) nitrite reductase (NAD(P)H), large subunit
M. leprae Br4923MLBr_02387lpd1e-0727.54% (167) dihydrolipoamide dehydrogenase
M. abscessus ATCC 19977MAB_3522c-0.069.71% (842) nitrite reductase
M. marinum MMMAR_0516nirB0.089.13% (846) nitrite reductase NAD(P)H large subunit
M. avium 104MAV_4904nirB0.089.42% (832) nitrite reductase
M. smegmatis MC2 155MSMEG_0427nirB0.077.49% (853) nitrite reductase
M. thermoresistible (build 8)TH_3739-3e-2930.80% (289) PUTATIVE Pyridine nucleotide-disulphide oxidoreductase
M. ulcerans Agy99MUL_0769-3e-2931.06% (293) ferredoxin reductase
M. vanbaalenii PYR-1Mvan_0297-0.079.03% (849) nitrite reductase (NAD(P)H), large subunit

CLUSTAL 2.0.9 multiple sequence alignment


Rv0252|M.tuberculosis_H37Rv         --------MPTAGSSRAPAAAREIVVVGHGMVGHRLVEAVRARDADGSLR
Mb0258|M.bovis_AF2122/97            --------MPTAGSSRAPAAAREIVVVGHGMVGHRLVEAVRARDADGSLR
MMAR_0516|M.marinum_M               --------MRAHDAN--PGVPRHVIVVGHGMVGHRMVEALRARDTDDRWR
MAV_4904|M.avium_104                ------------------------------MVGHRFVEALRARDTEGRWR
Mflv_0387|M.gilvum_PYR-GCK          -----------------MASNSHVVVVGHGMVGHRFVEALRSRDTEGTWR
Mvan_0297|M.vanbaalenii_PYR-1       -----------------MSSTSHVVVVGHGMVGHRFVEALRSRDTGDTWR
MSMEG_0427|M.smegmatis_MC2_155      -----------------MQSTRNVVVVGHGMVGHRFVEALRARDTEGSWR
MAB_3522c|M.abscessus_ATCC_199      -------------------MNKKVVVIGHGMVGHRFVQVLRERDATDQWQ
TH_3739|M.thermoresistible__bu      -----------------VSTTAGIIIVGGGLAAARTAEQLRRSEFGG--P
MUL_0769|M.ulcerans_Agy99           MYEHHVTSSEGVTQDPGATAANGIVIIGGGLAAARTAEQLRRAGYEG--Q
MLBr_02387|M.leprae_Br4923          MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAVVEPKYWGGICLNVGCIPSK
                                                                  :.  :    :          

Rv0252|M.tuberculosis_H37Rv         ITVLAEEGDAAYDRVGLTSYTESWDRALLALPGNDYAGDQR-----VRLL
Mb0258|M.bovis_AF2122/97            ITVLAEEGDAAYDRVGLTSYTESWDRALLALPGNDYAGDQR-----VRLL
MMAR_0516|M.marinum_M               VTVLAEEADAAYDRVGLTSYTETWDRAQLALPGNDYAGDER-----VRVL
MAV_4904|M.avium_104                ITVFAEEADAAYDRVGLTSYTESWDRALLALPGNDYQGDPQ-----VRLV
Mflv_0387|M.gilvum_PYR-GCK          VTVLAEELDAAYDRVGLTGYTDHWDRALLALPGNDYAADDL-----VEVR
Mvan_0297|M.vanbaalenii_PYR-1       VTVLAEELDAAYDRVGLTGYTEHWDRARLALPGNDYAGDPM-----VDVR
MSMEG_0427|M.smegmatis_MC2_155      VTVLGEEREAAYDRVGLTGYTEHWDRSLLALPGNEYAGDDL-----VELH
MAB_3522c|M.abscessus_ATCC_199      VTVLGEEADAAYDRVALSSYIDSWDRDTLALTGNDYAEDPM-----VTLH
TH_3739|M.thermoresistible__bu      ITIVSDEDHLPYDRPPLSKDVLSGKTDDVTLKPAEFYAEND-----ITLL
MUL_0769|M.ulcerans_Agy99           LTIVSDEVHLPYDRPPLSKEVLRSEVDDVSLKPREWYDEKG-----ITLR
MLBr_02387|M.leprae_Br4923          VLLHNAELAHIFTKEAKTFGISGDASFDYGIAYDRSRKVSEGRVAGVHFL
                                    : :   *    : :   :            :               : . 

Rv0252|M.tuberculosis_H37Rv         LNTRVTQIDRATKSVVTAAGQRHRYDTLVLATGSYAFVPPVPGHDLPACH
Mb0258|M.bovis_AF2122/97            LNTRVTQIDRATKSVVTAAGQRHRYDTLVLATGSYAFVPPVPGHDLPACH
MMAR_0516|M.marinum_M               LNTRVTEIDRAAKSVVTADGTRHGYDALVLATGSYAFVPPLPGHDLPGCH
MAV_4904|M.avium_104                LNQRVTEIDRATKSVVTADGQRHHYDTLVLATGSYAFVPPVPGHELPTCH
Mflv_0387|M.gilvum_PYR-GCK          LGQRVAAVDPAAKTVTTTDGTQIGYDALVLATGSYAFVPPVPGRDLPGCH
Mvan_0297|M.vanbaalenii_PYR-1       LGCRVTRLDPASKSVTTSDGTRIDYDALVLATGSYAFVPPVPGRDLPCCH
MSMEG_0427|M.smegmatis_MC2_155      LGSAVVEIDRPARTVRTADGCTFSYDALVLATGSYAFVPPVPGRDLPGCH
MAB_3522c|M.abscessus_ATCC_199      LGDPVVGIDRTNQTVSTAAGTVLDYDALVMATGSYPFVPPVPGGDAEGCF
TH_3739|M.thermoresistible__bu      LGTAATALDPQARKLTLADGRALEYDELIIATGLVPKRIPTLP-DLEGIR
MUL_0769|M.ulcerans_Agy99           LGSAATGLDTAAQTVTLADGTVLGYDELVIATGLVPRRIPAFP-ELEGIR
MLBr_02387|M.leprae_Br4923          MKKNKITEIHGYGRFTDANTLSVELSEGVPETPLKVTFNNVIIATGSKTR
                                    :             .  :       .  :  *                  

Rv0252|M.tuberculosis_H37Rv         VYRTFDDLDAIRAGAQRTLDGGHTDGGVVIGGGLLGLEAANALRQFGLQT
Mb0258|M.bovis_AF2122/97            VYRTFDDLDAIRAGAQRTLDGGHTDGGVVIGGGLLGLEAANALRQFGLQT
MMAR_0516|M.marinum_M               VYRTLDDLDAIHACAERALRDGHGGAGVVIGGGLLGLEAANALRQFGLQT
MAV_4904|M.avium_104                VYRTLDDLDAIRADAQRAAQTDHARAGVVIGGGLLGLEAANALRQFGLAT
Mflv_0387|M.gilvum_PYR-GCK          VYRTLDDLDAIRADALRTRETSRTPVGVVIGGGLLGLEAANALRGFGLTA
Mvan_0297|M.vanbaalenii_PYR-1       VYRTLDDLDAIRTDAMSATDGGRAPVGVVIGGGLLGLEAANALRGFGLSA
MSMEG_0427|M.smegmatis_MC2_155      VYRTLDDLDAIRASAANASK-SKSPVGVVIGGGLLGLEAANALRQFGLRT
MAB_3522c|M.abscessus_ATCC_199      VYRTMDDLDAIKATAD----KSPGSAGVVIGGGLLGLEAANALRLMGLAP
TH_3739|M.thermoresistible__bu      VLRTYDESMALRKHAG------SARNAVVIGAGFIGCEVAASLRGLGVHV
MUL_0769|M.ulcerans_Agy99           VLRSFDECMALRSHAS------AAKRAVVIGAGFIGCEVAASLRGLGVEV
MLBr_02387|M.leprae_Br4923          LVPGTLLSTNVITYEEQILTRELPDSIVIVGAGAIGIEFGYVLKNYGVDV
                                    :         :                *::*.* :* * .  *:  *:  

Rv0252|M.tuberculosis_H37Rv         HVVEMMPRLMAQQIDEAGGALLARMIADLGIAVHVGTGTESIESVK----
Mb0258|M.bovis_AF2122/97            HVVEMMPRLMAQQIDEAGGALLARMIADLGIAVHVGTGTESIESVK----
MMAR_0516|M.marinum_M               HVIEMMPRLMAQQIDEAGGALLARMVSDLGIAVHVGTGTDSIESVE----
MAV_4904|M.avium_104                HVVEMMPRLMAQQIDEAGGALLARMIGDLGISVHVGTGTEAIEPVE----
Mflv_0387|M.gilvum_PYR-GCK          HVVERSGRLMSQQLDEAGGALLGRMIGELGITVHTDVGTESIRPAQRNKP
Mvan_0297|M.vanbaalenii_PYR-1       HVVEKSPGLMAQQLDQAGAALLGTMITELGITVHTGVGTDVIAPAQRNRP
MSMEG_0427|M.smegmatis_MC2_155      HVLEMSPHLMAAQLDEAGGVLLNRMMRDLGIEVHTAVSTQSIAPAQKRKP
MAB_3522c|M.abscessus_ATCC_199      HVVELNPRLMHLQVDEGGGALLTRLVTDLGLTVHTSVSTQAIEKAA----
TH_3739|M.thermoresistible__bu      VLVEPQPTPLAGVLGEQIGALVARLHRDEGVDLRCGVGVADVRGTG----
MUL_0769|M.ulcerans_Agy99           VLVEPQPTPLAAVLGEQIGELVARLHRSEGVDVRTGVGVAEVRGDG----
MLBr_02387|M.leprae_Br4923          TIVEFLPRAMPNEDAEVS-KEIEKQFKKMGIKILTGTKVESISDNG----
                                     ::*     :     :     :     . *: :   . .  :        

Rv0252|M.tuberculosis_H37Rv         --HSDGSVWARVRLSDG--EVIDAGVVIFAAGIRPRDE--LARAAGLAIG
Mb0258|M.bovis_AF2122/97            --HSDGSVWARVRLSDG--EVIDAGVVIFAAGIRPRDE--LARAAGLAIG
MMAR_0516|M.marinum_M               --HSDGATSLRVRLAGG--DVIDAGALIFAAGIRPRDE--LARAAGLAIA
MAV_4904|M.avium_104                --GPDGSTTVRVRLSDG--QVIDAGLVIFAAGIRPRDE--LAVAAGLARA
Mflv_0387|M.gilvum_PYR-GCK          LKRSAEDNSMRVALSDG--TFIDAGVVVFAAGVRPRDE--LARDAGLEVA
Mvan_0297|M.vanbaalenii_PYR-1       VRRSEEDDSVRVTLSDG--TNIDAGVVVFAAGVRPRDE--LARDAGLAIA
MSMEG_0427|M.smegmatis_MC2_155      LRRSEIDDSLRVSLDDG--TAIDAGVVIFAAGVRPRDE--LAREAGLDMA
MAB_3522c|M.abscessus_ATCC_199      ------DGTLSVQLSDG--STIDASVLVFSAGIRPRDE--LARECGLELA
TH_3739|M.thermoresistible__bu      -------AVEKVVLDDG--TELDADLVVVGIGSTPATD--WLQGSGVEVD
MUL_0769|M.ulcerans_Agy99           -------HVDTVVLADG--TQLDADLVVVGIGSHPATG--WLDGSGIAVD
MLBr_02387|M.leprae_Br4923          ------SHVLVAVSKDGQFQELKADKVLQAIGFAPNVDGYGLDKVGVALT
                                               .   .*    :.*. :: . *  *          *:   

Rv0252|M.tuberculosis_H37Rv         DRGGVLTDLSCRTSDPDIYAVGEVAAIDGRCYGLVGPGYTSAEVVADRLL
Mb0258|M.bovis_AF2122/97            DRGGVLTDLSCRTSDPDIYAVGEVAAIDGRCYGLVGPGYTSAEVVADRLL
MMAR_0516|M.marinum_M               ERGGVLTDLSCQTSDPDIYAVGEVAAIEGRCYGLVGPGYTSAEVVADRLL
MAV_4904|M.avium_104                ERGGVLTDLSCRTSDPDIYAIGEVAAIDGRCYGLVGPGYTSAEVVADRLL
Mflv_0387|M.gilvum_PYR-GCK          ERGGVLTDLGCVTSDPAVYAIGEVAAIEGRCYGLVGPGYTSAEVVADRIL
Mvan_0297|M.vanbaalenii_PYR-1       DRGGVLTDVACATSDPNIYAIGEVAAVEGRCYGLVGPGYTSAEVVADRLL
MSMEG_0427|M.smegmatis_MC2_155      QRGGVLTDSNCVTSDPNIYAIGEVAAVDGRCYGLVAPGYTTAEVVADRLL
MAB_3522c|M.abscessus_ATCC_199      ERGGIFTDLGCQTSDLHIYAIGEVAAIEGRCYGLVAPGYTTAEIVADRLL
TH_3739|M.thermoresistible__bu      N--GVVCDAVGRTNVEHVWAIGDVASWRNTVGKQVRVEHWSNVADQARVL
MUL_0769|M.ulcerans_Agy99           N--GVVCDAAGRTSAPNVWAFGDVASWRDQMGHQVRVEHWSNVADQARVV
MLBr_02387|M.leprae_Br4923          ADKAVDIDDYMQTNVSHIYAIGDVTGKLQLAHVAEAQGVVAAEAIAG---
                                       .:  *    *.   ::*.*:*:.              :         

Rv0252|M.tuberculosis_H37Rv         DGSAEFPEADLSTKLKLLGVDVASFGDAMGATEN-CLEVVINDAVKRTYA
Mb0258|M.bovis_AF2122/97            DGSAEFPEADLSTKLKLLGVDVASFGDAMGATEN-CLEVVINDAVKRTYA
MMAR_0516|M.marinum_M               NGVAEFPEADLSTKLKLLGVDVASFGDAMGATEN-CLEVAVNDAVNRTYA
MAV_4904|M.avium_104                DGSAEFGEADLSTKLKLLGVDVASFGDAMGTTEN-CLEVAINDAVNRTYA
Mflv_0387|M.gilvum_PYR-GCK          GGAAEFPEADMSTKLKLLGVDVASFGDAMGVTPD-CLEVAVNDAVNQTYA
Mvan_0297|M.vanbaalenii_PYR-1       GGGAEFPEADMSTKLKLLGVDVASFGDAMGRTPN-CLEVVVNDAVNQTYA
MSMEG_0427|M.smegmatis_MC2_155      GGSAEFPGADMSTKLKLLGVDVASFGDAKGITPN-CLEVVVNDPVKQTYA
MAB_3522c|M.abscessus_ATCC_199      GGSAQFPGADLSTKLKLLGVDVASFGDAHATADG-ALEVVFNDATKGTYA
TH_3739|M.thermoresistible__bu      VPALLGQEVPVAATVPYF------WSDQYDVKIQ-CLGEPE-----AGDT
MUL_0769|M.ulcerans_Agy99           VPAMLGREVSSNVVVPYF------WSDQYDVKIQ-CLGEPH-----STDV
MLBr_02387|M.leprae_Br4923          AETLALSDYRMMPRATFCQPNVASFGLTEQQARDGGYDVVVAKFPFTANA
                                                            :.                       .

Rv0252|M.tuberculosis_H37Rv         KLVLSDDATTLLGGVLVGDASSYGVLRPMVGAELPGDPLALIAPAGSGAG
Mb0258|M.bovis_AF2122/97            KLVLSDDATTLLGGVLVGDASSYGVLRPMVGAELPGDPLALIAPAGSGAG
MMAR_0516|M.marinum_M               KLVLSDDAKTLLGGVLVGDASAYGVLRPMVGSELPGDPLALISPA-SGDG
MAV_4904|M.avium_104                KLVLSDDAKTLLGGVLVGDASSYGVLRPMVGSELPGDPLALIAPASSGGG
Mflv_0387|M.gilvum_PYR-GCK          KLVLSDDAKTLLGGILVGDASAYGVLRPMVGEELPGDPLALIAPAGTEGG
Mvan_0297|M.vanbaalenii_PYR-1       KLVLSDDAKTLLGGILVGDASSYGLLRPMVGEPLPGAPLALITPAGAEGG
MSMEG_0427|M.smegmatis_MC2_155      KLVLSDDAKTLLGGILVGDASAYGVLRPMVASELPGDPLALIAPT-TGGD
MAB_3522c|M.abscessus_ATCC_199      KLVVSDDARTLLGGILVGDASAYGTLRPMLGRELPADPASLIAPS-----
TH_3739|M.thermoresistible__bu      VHVVSDDGRKFLAYYER-----DGVLTGVVGGGMPG--------------
MUL_0769|M.ulcerans_Agy99           VHLVEDDGRKLLAYYQR-----DGVLVGVVGGGVPG--------------
MLBr_02387|M.leprae_Br4923          KAHGMGDPSGFVK------LVADAKYGELLGGHMIGHNVSELLP------
                                         .*   ::           .    ::.  : .              

Rv0252|M.tuberculosis_H37Rv         AGALGVGALPDSAQICSCNNVTKGELKCAIADGCGDVPALKSCTAAGTSC
Mb0258|M.bovis_AF2122/97            AGALGVGALPDSAQICSCNNVTKGELKCAIADGCGDVPALKSCTAAGTSC
MMAR_0516|M.marinum_M               AGALGIGALPDSAQICSCNNVTKGELKCAIADGCADVPALKACTAAGTSC
MAV_4904|M.avium_104                T-ALGVGALPDSAQICSCNNVTKGDLKCAIADGCADVAALKSCTSAGTSC
Mflv_0387|M.gilvum_PYR-GCK          ATQLGVGALPDAAQICSCNNVTKGDLTGAIAGGCCDVADLKRCTLAGTSC
Mvan_0297|M.vanbaalenii_PYR-1       G-GLGVGALPDGAQICSCNNVTKGALTEAIGSGCCDVPALKKCTLAGTSC
MSMEG_0427|M.smegmatis_MC2_155      APGLGVGALPDIAQICSCNNVTKGDLTEAIAGGCCDVADLKKCTLAGTSC
MAB_3522c|M.abscessus_ATCC_199      GAEIGVGALPDDAQICSCNAVTKGAICAAICEGATDVPALKSATCAGTSC
TH_3739|M.thermoresistible__bu      -----------------------------------------KVMKARAKI
MUL_0769|M.ulcerans_Agy99           -----------------------------------------KVMKVRAKI
MLBr_02387|M.leprae_Br4923          -----------------------------------------ELTLAQKWD
                                                                                 .    

Rv0252|M.tuberculosis_H37Rv         GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFEIITATEVRTFSGLLD
Mb0258|M.bovis_AF2122/97            GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFEIITATEVRTFSGLLD
MMAR_0516|M.marinum_M               GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFQIISATEIRTFSGLLQ
MAV_4904|M.avium_104                GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFEIISATEIRTFSGLLE
Mflv_0387|M.gilvum_PYR-GCK          GSCVPLLKQLLEAEGVEQSKALCEHFSHSRAELFEIVSATSIRTFSGLIE
Mvan_0297|M.vanbaalenii_PYR-1       GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFELISATEVRTFSGLIE
MSMEG_0427|M.smegmatis_MC2_155      GSCVPLLKQLLEAQGVEQSKALCEHFSQSRAELFEIISATEIRTFSGLIE
MAB_3522c|M.abscessus_ATCC_199      GSCIPMLKQILAAQGVEQSKALCEHFEQSRAELFQVVQATGIRTFSELIA
TH_3739|M.thermoresistible__bu      AAGAPISEVLE---------------------------------------
MUL_0769|M.ulcerans_Agy99           AAAVPISEMLDESQGQT----------------------------SARIP
MLBr_02387|M.leprae_Br4923          LTATELVRNVHTHPTLSEALQECFHGLIGHMINF----------------
                                     :   : . :                                        

Rv0252|M.tuberculosis_H37Rv         RFGRGKGCDICKPVVASILASTGSDHILDGEQASLQDSNDHFLANIQKNG
Mb0258|M.bovis_AF2122/97            RFGRGKGCDICKPVVASILASTGSDHILDGEQASLQDSNDHFLANIQKNG
MMAR_0516|M.marinum_M               RFGRGKGCDICKPVVASILASTGSDHILDGEQASLQDSNDHFLANIQKNG
MAV_4904|M.avium_104                RFGRGKGCDICKPVVASILASTGSEHILEGEQASLQDSNDHFLANIQKNG
Mflv_0387|M.gilvum_PYR-GCK          RFGTGKGCDICKPVVASILASTSSEHILDGEQASLQDSNDHFLANIQRNG
Mvan_0297|M.vanbaalenii_PYR-1       RFGSGKGCDICKPVVASILASTSSTHILDGEQASLQDTNDHFLANIQRNG
MSMEG_0427|M.smegmatis_MC2_155      RFGTGKGCDICKPTIASILASTSSDHILDGEQAALQDSNDHFLANIQRNG
MAB_3522c|M.abscessus_ATCC_199      KHGKGTGCDICKPTVASILASTSSDHILEGEQAGLQDTNDHFLANMQKNG
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           ARGAGPGGPLVR------------------------------WPTLTKSG
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0252|M.tuberculosis_H37Rv         SYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDLFGARVDQL
Mb0258|M.bovis_AF2122/97            SYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDLFGARVDQL
MMAR_0516|M.marinum_M               SYSVVPRVPGGDIKPEHLILIGQIAQEFGLYTKITGGQRIDMFGARVDQL
MAV_4904|M.avium_104                SYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDMFGARVDQL
Mflv_0387|M.gilvum_PYR-GCK          SYSVVPRVPGGDITPEHLILIGQIAKDFGLYTKITGGQRIDMFGARVDQL
Mvan_0297|M.vanbaalenii_PYR-1       SYSVVPRVPGGDITPEQLILIGEIARDFGLYTKITGGQRIDMFGARVEQL
MSMEG_0427|M.smegmatis_MC2_155      SYSVVPRVPGGDITPEQLILIGEIARDFGLYTKITGGQRIDMFGARVEQL
MAB_3522c|M.abscessus_ATCC_199      TYSVVPRLPGGEVTPEKLIVIGEIARDFGLYTKITGGQRIDLFGARVEQL
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           RWRAEKATASSPVARVDGIGLEPGPRRTASWPDVPGT-------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0252|M.tuberculosis_H37Rv         PLIWQRLVDGGMESGHAYGKAVRTVKSCVGSDWCRYGQQDSVQLAIDLEL
Mb0258|M.bovis_AF2122/97            PLIWQRLVDGGMESGHAYGKAVRTVKSCVGSDWCRYGQQDSVQLAIDLEL
MMAR_0516|M.marinum_M               PLIWKRLVDAGMESGHAYGKALRTVKSCVGSDWCRYGQQDSVQLAIDLEL
MAV_4904|M.avium_104                PAIWKRLVDGGMESGHAYGKALRTVKSCVGTDWCRYGQQDSVQLAIDLEL
Mflv_0387|M.gilvum_PYR-GCK          PEIWRRLVEGGMESGQAYGKSLRTVKSCVGSDWCRYGQQDSVQMAINLEL
Mvan_0297|M.vanbaalenii_PYR-1       PEIWRRLVEGGMESGHAYGKSLRTVKSCVGSDWCRYGQQDSVQMAINLEL
MSMEG_0427|M.smegmatis_MC2_155      PEIWRRLVEGGMESGHAYGKSLRTVKSCVGSDWCRYGQQDSVQMAINLEL
MAB_3522c|M.abscessus_ATCC_199      PLIWKRLIDAGMESGHAYGKSLRTVKSCVGSTWCRYGVQDSVAMAVELEL
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0252|M.tuberculosis_H37Rv         RYRGLRAPHKIKLGVSGCARECAEARGKDVGVIATEKGWNLYVAGNGGMT
Mb0258|M.bovis_AF2122/97            RYRGLRAPHKIKLGVSGCARECAEARGKDVGVIATEKGWNLYVAGNGGMT
MMAR_0516|M.marinum_M               RYRGLRAPHKIKLGVSGCARECAEARSKDVGVIATEKGWNLYVGGNGGMT
MAV_4904|M.avium_104                RYRGLRAPHKIKMGVSGCARECAEARSKDVGVIATEKGWNLYVGGNGGMT
Mflv_0387|M.gilvum_PYR-GCK          RYRGLRAPHKIKMGVSGCARECAEARGKDVGVIATETGWNLYIGGNGGMT
Mvan_0297|M.vanbaalenii_PYR-1       RYRGLRAPHKIKMGVSGCARECAEARGKDVGVIATETGWNLYVGGNGGMT
MSMEG_0427|M.smegmatis_MC2_155      RYRGLRAPHKIKMGVSGCARECAEARGKDVGVIATDSGWNLYVGGNGGMT
MAB_3522c|M.abscessus_ATCC_199      RYRGLRSPHKLKMGVSGCARECAEARGKDVGVIATENGWNLYVGGNGGAT
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0252|M.tuberculosis_H37Rv         PKHAQLLASDLDKETLIRYIDRFLIYYIRTADRLQRTAPWVESLG--LDH
Mb0258|M.bovis_AF2122/97            PKHAQLLASDLDKETLIRYIDRFLIYYIRTADRLQRTAPWVESLG--LDH
MMAR_0516|M.marinum_M               PKHAQLLASDLDTETLVRYIDRFLMYYVRTADRLQRTAPWVESLEGGLDH
MAV_4904|M.avium_104                PKHAQLLASDLDTETLVRYIDRFVMYYIRTADRLQRTAPWVESLDGGLDH
Mflv_0387|M.gilvum_PYR-GCK          PKHAQLLAGDLDDETLVRYIDRFLMFYIRTADRLQRTAPWVEQLG--LEH
Mvan_0297|M.vanbaalenii_PYR-1       PRHAELLAGDLDDETLIRYIDRFLMFYIRTADRLQRTAPWVEQVG--LEH
MSMEG_0427|M.smegmatis_MC2_155      PRHAQLLAGDLDDETLIRYIDRFLMFYIRTADRLQRTAPWVEALDGGIDH
MAB_3522c|M.abscessus_ATCC_199      PAHAKLLAGDLDSETLIRYIDRYLMFYIRTADRLQRTAPWQEAIEGGLDH
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0252|M.tuberculosis_H37Rv         VREVVCEDSLGLAEEFEAAMQRHVANYKCEWKGVLEDPDKLSRFVSFVNA
Mb0258|M.bovis_AF2122/97            VREVVCEDSLGLAEEFEAAMQRHVANYKCEWKGVLEDPDKLSRFVSFVNA
MMAR_0516|M.marinum_M               VREVVCDDSLGLAEEFEAAVQHHIANYKCEWKGVLEDPDKLSRFVSFVNA
MAV_4904|M.avium_104                VREVVCEDSLGLAEEFEAAMERHVRNYKCEWKGVLDDPDKLSRFVSFVNA
Mflv_0387|M.gilvum_PYR-GCK          LREVICDDSLGLAAEFEAAVQRHVDGYACEWKGVLEDPDKLSRFVSFVNA
Mvan_0297|M.vanbaalenii_PYR-1       LREVVCEDSLGLAEEFEAAIARHVEGYACEWKGVLSDPDKLSRFVSFVNA
MSMEG_0427|M.smegmatis_MC2_155      LRDVVCDDSLGLAEEFEAAMARHVEGYACEWKGVLQDPDKLARFVSFVNA
MAB_3522c|M.abscessus_ATCC_199      IRAVVCEDSLGIADELEAAMARHVQGYQDEWAAVLADPDKLRRFVSFVNA
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0252|M.tuberculosis_H37Rv         PDAVDSTVTFTERAGRKVP----VSIGIPRVRS------
Mb0258|M.bovis_AF2122/97            PDAVDSTVTFTERAGRKVP----VSIGIPRVRS------
MMAR_0516|M.marinum_M               PDAADPTVAFTERAGRKVP----VSIGIPRVRS------
MAV_4904|M.avium_104                PDAVDSTVAFTEHAGRKIP----VSIGMPKIRQG-----
Mflv_0387|M.gilvum_PYR-GCK          PDVPDPTIEFTEIAGRKVP--SPVAIGMPKVGR------
Mvan_0297|M.vanbaalenii_PYR-1       PDVPDPTVTFTENAGRMVP--APVSIGMPKIGR------
MSMEG_0427|M.smegmatis_MC2_155      PDTPDPTVSFTERSGRKVPDLRPVSIGMPTIRPLQEMS-
MAB_3522c|M.abscessus_ATCC_199      PDQPDSTIAFDESGPRKVP----VLLGTPGFRAAAEAAT
TH_3739|M.thermoresistible__bu      ---------------------------------------
MUL_0769|M.ulcerans_Agy99           ---------------------------------------
MLBr_02387|M.leprae_Br4923          ---------------------------------------