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M. vanbaalenii PYR-1 Mvan_0297 (-)

annotation: nitrite reductase (NAD(P)H), large subunit
coordinates: 331318 - 333873
length: 851

MSSTSHVVVVGHGMVGHRFVEALRSRDTGDTWRVTVLAEELDAAYDRVGLTGYTEHWDRARLALPGNDYA
GDPMVDVRLGCRVTRLDPASKSVTTSDGTRIDYDALVLATGSYAFVPPVPGRDLPCCHVYRTLDDLDAIR
TDAMSATDGGRAPVGVVIGGGLLGLEAANALRGFGLSAHVVEKSPGLMAQQLDQAGAALLGTMITELGIT
VHTGVGTDVIAPAQRNRPVRRSEEDDSVRVTLSDGTNIDAGVVVFAAGVRPRDELARDAGLAIADRGGVL
TDVACATSDPNIYAIGEVAAVEGRCYGLVGPGYTSAEVVADRLLGGGAEFPEADMSTKLKLLGVDVASFG
DAMGRTPNCLEVVVNDAVNQTYAKLVLSDDAKTLLGGILVGDASSYGLLRPMVGEPLPGAPLALITPAGA
EGGGGLGVGALPDGAQICSCNNVTKGALTEAIGSGCCDVPALKKCTLAGTSCGSCVPLLKQLLEAEGVEQ
SKALCEHFSQSRAELFELISATEVRTFSGLIERFGSGKGCDICKPVVASILASTSSTHILDGEQASLQDT
NDHFLANIQRNGSYSVVPRVPGGDITPEQLILIGEIARDFGLYTKITGGQRIDMFGARVEQLPEIWRRLV
EGGMESGHAYGKSLRTVKSCVGSDWCRYGQQDSVQMAINLELRYRGLRAPHKIKMGVSGCARECAEARGK
DVGVIATETGWNLYVGGNGGMTPRHAELLAGDLDDETLIRYIDRFLMFYIRTADRLQRTAPWVEQVGLEH
LREVVCEDSLGLAEEFEAAIARHVEGYACEWKGVLSDPDKLSRFVSFVNAPDVPDPTVTFTENAGRMVPA
PVSIGMPKIGR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_0297--100% (851)nitrite reductase (NAD(P)H), large subunit
M. vanbaalenii PYR-1Mvan_3494-e-13337.89% (842) nitrite reductase (NAD(P)H), large subunit
M. vanbaalenii PYR-1Mvan_1290-4e-3232.82% (326) FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0258nirB0.079.03% (849) nitrite reductase
M. gilvum PYR-GCKMflv_0387-0.086.74% (852) nitrite reductase (NAD(P)H), large subunit
M. tuberculosis H37RvRv0252nirB0.079.03% (849) nitrite reductase large subunit
M. leprae Br4923MLBr_02387lpd1e-0525.27% (277) dihydrolipoamide dehydrogenase
M. abscessus ATCC 19977MAB_3522c-0.070.46% (843) nitrite reductase
M. marinum MMMAR_0516nirB0.079.20% (846) nitrite reductase NAD(P)H large subunit
M. avium 104MAV_4904nirB0.079.71% (838) nitrite reductase
M. smegmatis MC2 155MSMEG_0427nirB0.083.24% (853) nitrite reductase
M. thermoresistible (build 8)TH_3739-2e-2930.23% (301) PUTATIVE Pyridine nucleotide-disulphide oxidoreductase
M. ulcerans Agy99MUL_0769-4e-3132.00% (300) ferredoxin reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0258|M.bovis_AF2122/97            --------MPTAGSSRAPAAAREIVVVGHGMVGHRLVEAVRARDADGSLR
Rv0252|M.tuberculosis_H37Rv         --------MPTAGSSRAPAAAREIVVVGHGMVGHRLVEAVRARDADGSLR
MMAR_0516|M.marinum_M               --------MRAHDAN--PGVPRHVIVVGHGMVGHRMVEALRARDTDDRWR
MAV_4904|M.avium_104                ------------------------------MVGHRFVEALRARDTEGRWR
Mvan_0297|M.vanbaalenii_PYR-1       -----------------MSSTSHVVVVGHGMVGHRFVEALRSRDTGDTWR
Mflv_0387|M.gilvum_PYR-GCK          -----------------MASNSHVVVVGHGMVGHRFVEALRSRDTEGTWR
MSMEG_0427|M.smegmatis_MC2_155      -----------------MQSTRNVVVVGHGMVGHRFVEALRARDTEGSWR
MAB_3522c|M.abscessus_ATCC_199      -------------------MNKKVVVIGHGMVGHRFVQVLRERDATDQWQ
TH_3739|M.thermoresistible__bu      -----------------VSTTAGIIIVGGGLAAARTAEQLRRSEFGG--P
MUL_0769|M.ulcerans_Agy99           MYEHHVTSSEGVTQDPGATAANGIVIIGGGLAAARTAEQLRRAGYEG--Q
MLBr_02387|M.leprae_Br4923          MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAVVEPKYWGGICLNVGCIPSK
                                                                  :.  :    :          

Mb0258|M.bovis_AF2122/97            ITVLAEEGDAAYDRVGLTSYTESWDRALLALPGNDYAGDQR-----VRLL
Rv0252|M.tuberculosis_H37Rv         ITVLAEEGDAAYDRVGLTSYTESWDRALLALPGNDYAGDQR-----VRLL
MMAR_0516|M.marinum_M               VTVLAEEADAAYDRVGLTSYTETWDRAQLALPGNDYAGDER-----VRVL
MAV_4904|M.avium_104                ITVFAEEADAAYDRVGLTSYTESWDRALLALPGNDYQGDPQ-----VRLV
Mvan_0297|M.vanbaalenii_PYR-1       VTVLAEELDAAYDRVGLTGYTEHWDRARLALPGNDYAGDPM-----VDVR
Mflv_0387|M.gilvum_PYR-GCK          VTVLAEELDAAYDRVGLTGYTDHWDRALLALPGNDYAADDL-----VEVR
MSMEG_0427|M.smegmatis_MC2_155      VTVLGEEREAAYDRVGLTGYTEHWDRSLLALPGNEYAGDDL-----VELH
MAB_3522c|M.abscessus_ATCC_199      VTVLGEEADAAYDRVALSSYIDSWDRDTLALTGNDYAEDPM-----VTLH
TH_3739|M.thermoresistible__bu      ITIVSDEDHLPYDRPPLSKDVLSGKTDDVTLKPAEFYAEND-----ITLL
MUL_0769|M.ulcerans_Agy99           LTIVSDEVHLPYDRPPLSKEVLRSEVDDVSLKPREWYDEKG-----ITLR
MLBr_02387|M.leprae_Br4923          VLLHNAELAHIFTKEAKTFGISGDASFDYGIAYDRSRKVSEGRVAGVHFL
                                    : :   *    : :   :            :               : . 

Mb0258|M.bovis_AF2122/97            LNTRVTQIDRATKSVVTAAGQRHRYDTLVLATGSYAFVPPVPGHDLPACH
Rv0252|M.tuberculosis_H37Rv         LNTRVTQIDRATKSVVTAAGQRHRYDTLVLATGSYAFVPPVPGHDLPACH
MMAR_0516|M.marinum_M               LNTRVTEIDRAAKSVVTADGTRHGYDALVLATGSYAFVPPLPGHDLPGCH
MAV_4904|M.avium_104                LNQRVTEIDRATKSVVTADGQRHHYDTLVLATGSYAFVPPVPGHELPTCH
Mvan_0297|M.vanbaalenii_PYR-1       LGCRVTRLDPASKSVTTSDGTRIDYDALVLATGSYAFVPPVPGRDLPCCH
Mflv_0387|M.gilvum_PYR-GCK          LGQRVAAVDPAAKTVTTTDGTQIGYDALVLATGSYAFVPPVPGRDLPGCH
MSMEG_0427|M.smegmatis_MC2_155      LGSAVVEIDRPARTVRTADGCTFSYDALVLATGSYAFVPPVPGRDLPGCH
MAB_3522c|M.abscessus_ATCC_199      LGDPVVGIDRTNQTVSTAAGTVLDYDALVMATGSYPFVPPVPGGDAEGCF
TH_3739|M.thermoresistible__bu      LGTAATALDPQARKLTLADGRALEYDELIIATGLVPKRIPTLP-DLEGIR
MUL_0769|M.ulcerans_Agy99           LGSAATGLDTAAQTVTLADGTVLGYDELVIATGLVPRRIPAFP-ELEGIR
MLBr_02387|M.leprae_Br4923          MKKNKITEIHGYGRFTDANTLSVELSEGVPETPLKVTFNNVIIATGSKTR
                                    :             .  :       .  :  *                  

Mb0258|M.bovis_AF2122/97            VYRTFDDLDAIRAGAQRTLDGGHTDGGVVIGGGLLGLEAANALRQFGLQT
Rv0252|M.tuberculosis_H37Rv         VYRTFDDLDAIRAGAQRTLDGGHTDGGVVIGGGLLGLEAANALRQFGLQT
MMAR_0516|M.marinum_M               VYRTLDDLDAIHACAERALRDGHGGAGVVIGGGLLGLEAANALRQFGLQT
MAV_4904|M.avium_104                VYRTLDDLDAIRADAQRAAQTDHARAGVVIGGGLLGLEAANALRQFGLAT
Mvan_0297|M.vanbaalenii_PYR-1       VYRTLDDLDAIRTDAMSATDGGRAPVGVVIGGGLLGLEAANALRGFGLSA
Mflv_0387|M.gilvum_PYR-GCK          VYRTLDDLDAIRADALRTRETSRTPVGVVIGGGLLGLEAANALRGFGLTA
MSMEG_0427|M.smegmatis_MC2_155      VYRTLDDLDAIRASAANASK-SKSPVGVVIGGGLLGLEAANALRQFGLRT
MAB_3522c|M.abscessus_ATCC_199      VYRTMDDLDAIKATAD----KSPGSAGVVIGGGLLGLEAANALRLMGLAP
TH_3739|M.thermoresistible__bu      VLRTYDESMALRKHAG------SARNAVVIGAGFIGCEVAASLRGLGVHV
MUL_0769|M.ulcerans_Agy99           VLRSFDECMALRSHAS------AAKRAVVIGAGFIGCEVAASLRGLGVEV
MLBr_02387|M.leprae_Br4923          LVPGTLLSTNVITYEEQILTRELPDSIVIVGAGAIGIEFGYVLKNYGVDV
                                    :         :                *::*.* :* * .  *:  *:  

Mb0258|M.bovis_AF2122/97            HVVEMMPRLMAQQIDEAGGALLARMIADLGIAVHVGTGTESIESVK----
Rv0252|M.tuberculosis_H37Rv         HVVEMMPRLMAQQIDEAGGALLARMIADLGIAVHVGTGTESIESVK----
MMAR_0516|M.marinum_M               HVIEMMPRLMAQQIDEAGGALLARMVSDLGIAVHVGTGTDSIESVE----
MAV_4904|M.avium_104                HVVEMMPRLMAQQIDEAGGALLARMIGDLGISVHVGTGTEAIEPVE----
Mvan_0297|M.vanbaalenii_PYR-1       HVVEKSPGLMAQQLDQAGAALLGTMITELGITVHTGVGTDVIAPAQRNRP
Mflv_0387|M.gilvum_PYR-GCK          HVVERSGRLMSQQLDEAGGALLGRMIGELGITVHTDVGTESIRPAQRNKP
MSMEG_0427|M.smegmatis_MC2_155      HVLEMSPHLMAAQLDEAGGVLLNRMMRDLGIEVHTAVSTQSIAPAQKRKP
MAB_3522c|M.abscessus_ATCC_199      HVVELNPRLMHLQVDEGGGALLTRLVTDLGLTVHTSVSTQAIEKAA----
TH_3739|M.thermoresistible__bu      VLVEPQPTPLAGVLGEQIGALVARLHRDEGVDLRCGVGVADVRGTG----
MUL_0769|M.ulcerans_Agy99           VLVEPQPTPLAAVLGEQIGELVARLHRSEGVDVRTGVGVAEVRGDG----
MLBr_02387|M.leprae_Br4923          TIVEFLPRAMPNEDAEVS-KEIEKQFKKMGIKILTGTKVESISDNG----
                                     ::*     :     :     :     . *: :   . .  :        

Mb0258|M.bovis_AF2122/97            --HSDGSVWARVRLSDG--EVIDAGVVIFAAGIRPRDE--LARAAGLAIG
Rv0252|M.tuberculosis_H37Rv         --HSDGSVWARVRLSDG--EVIDAGVVIFAAGIRPRDE--LARAAGLAIG
MMAR_0516|M.marinum_M               --HSDGATSLRVRLAGG--DVIDAGALIFAAGIRPRDE--LARAAGLAIA
MAV_4904|M.avium_104                --GPDGSTTVRVRLSDG--QVIDAGLVIFAAGIRPRDE--LAVAAGLARA
Mvan_0297|M.vanbaalenii_PYR-1       VRRSEEDDSVRVTLSDG--TNIDAGVVVFAAGVRPRDE--LARDAGLAIA
Mflv_0387|M.gilvum_PYR-GCK          LKRSAEDNSMRVALSDG--TFIDAGVVVFAAGVRPRDE--LARDAGLEVA
MSMEG_0427|M.smegmatis_MC2_155      LRRSEIDDSLRVSLDDG--TAIDAGVVIFAAGVRPRDE--LAREAGLDMA
MAB_3522c|M.abscessus_ATCC_199      ------DGTLSVQLSDG--STIDASVLVFSAGIRPRDE--LARECGLELA
TH_3739|M.thermoresistible__bu      -------AVEKVVLDDG--TELDADLVVVGIGSTPATD--WLQGSGVEVD
MUL_0769|M.ulcerans_Agy99           -------HVDTVVLADG--TQLDADLVVVGIGSHPATG--WLDGSGIAVD
MLBr_02387|M.leprae_Br4923          ------SHVLVAVSKDGQFQELKADKVLQAIGFAPNVDGYGLDKVGVALT
                                               .   .*    :.*. :: . *  *          *:   

Mb0258|M.bovis_AF2122/97            DRGGVLTDLSCRTSDPDIYAVGEVAAIDGRCYGLVGPGYTSAEVVADRLL
Rv0252|M.tuberculosis_H37Rv         DRGGVLTDLSCRTSDPDIYAVGEVAAIDGRCYGLVGPGYTSAEVVADRLL
MMAR_0516|M.marinum_M               ERGGVLTDLSCQTSDPDIYAVGEVAAIEGRCYGLVGPGYTSAEVVADRLL
MAV_4904|M.avium_104                ERGGVLTDLSCRTSDPDIYAIGEVAAIDGRCYGLVGPGYTSAEVVADRLL
Mvan_0297|M.vanbaalenii_PYR-1       DRGGVLTDVACATSDPNIYAIGEVAAVEGRCYGLVGPGYTSAEVVADRLL
Mflv_0387|M.gilvum_PYR-GCK          ERGGVLTDLGCVTSDPAVYAIGEVAAIEGRCYGLVGPGYTSAEVVADRIL
MSMEG_0427|M.smegmatis_MC2_155      QRGGVLTDSNCVTSDPNIYAIGEVAAVDGRCYGLVAPGYTTAEVVADRLL
MAB_3522c|M.abscessus_ATCC_199      ERGGIFTDLGCQTSDLHIYAIGEVAAIEGRCYGLVAPGYTTAEIVADRLL
TH_3739|M.thermoresistible__bu      N--GVVCDAVGRTNVEHVWAIGDVASWRNTVGKQVRVEHWSNVADQARVL
MUL_0769|M.ulcerans_Agy99           N--GVVCDAAGRTSAPNVWAFGDVASWRDQMGHQVRVEHWSNVADQARVV
MLBr_02387|M.leprae_Br4923          ADKAVDIDDYMQTNVSHIYAIGDVTGKLQLAHVAEAQGVVAAEAIAG---
                                       .:  *    *.   ::*.*:*:.              :         

Mb0258|M.bovis_AF2122/97            DGSAEFPEADLSTKLKLLGVDVASFGDAMGATEN-CLEVVINDAVKRTYA
Rv0252|M.tuberculosis_H37Rv         DGSAEFPEADLSTKLKLLGVDVASFGDAMGATEN-CLEVVINDAVKRTYA
MMAR_0516|M.marinum_M               NGVAEFPEADLSTKLKLLGVDVASFGDAMGATEN-CLEVAVNDAVNRTYA
MAV_4904|M.avium_104                DGSAEFGEADLSTKLKLLGVDVASFGDAMGTTEN-CLEVAINDAVNRTYA
Mvan_0297|M.vanbaalenii_PYR-1       GGGAEFPEADMSTKLKLLGVDVASFGDAMGRTPN-CLEVVVNDAVNQTYA
Mflv_0387|M.gilvum_PYR-GCK          GGAAEFPEADMSTKLKLLGVDVASFGDAMGVTPD-CLEVAVNDAVNQTYA
MSMEG_0427|M.smegmatis_MC2_155      GGSAEFPGADMSTKLKLLGVDVASFGDAKGITPN-CLEVVVNDPVKQTYA
MAB_3522c|M.abscessus_ATCC_199      GGSAQFPGADLSTKLKLLGVDVASFGDAHATADG-ALEVVFNDATKGTYA
TH_3739|M.thermoresistible__bu      VPALLGQEVPVAATVPYF------WSDQYDVKIQ-CLGEPE-----AGDT
MUL_0769|M.ulcerans_Agy99           VPAMLGREVSSNVVVPYF------WSDQYDVKIQ-CLGEPH-----STDV
MLBr_02387|M.leprae_Br4923          AETLALSDYRMMPRATFCQPNVASFGLTEQQARDGGYDVVVAKFPFTANA
                                                            :.                       .

Mb0258|M.bovis_AF2122/97            KLVLSDDATTLLGGVLVGDASSYGVLRPMVGAELPGDPLALIAPAGSGAG
Rv0252|M.tuberculosis_H37Rv         KLVLSDDATTLLGGVLVGDASSYGVLRPMVGAELPGDPLALIAPAGSGAG
MMAR_0516|M.marinum_M               KLVLSDDAKTLLGGVLVGDASAYGVLRPMVGSELPGDPLALISPA-SGDG
MAV_4904|M.avium_104                KLVLSDDAKTLLGGVLVGDASSYGVLRPMVGSELPGDPLALIAPASSGGG
Mvan_0297|M.vanbaalenii_PYR-1       KLVLSDDAKTLLGGILVGDASSYGLLRPMVGEPLPGAPLALITPAGAEGG
Mflv_0387|M.gilvum_PYR-GCK          KLVLSDDAKTLLGGILVGDASAYGVLRPMVGEELPGDPLALIAPAGTEGG
MSMEG_0427|M.smegmatis_MC2_155      KLVLSDDAKTLLGGILVGDASAYGVLRPMVASELPGDPLALIAPT-TGGD
MAB_3522c|M.abscessus_ATCC_199      KLVVSDDARTLLGGILVGDASAYGTLRPMLGRELPADPASLIAPS-----
TH_3739|M.thermoresistible__bu      VHVVSDDGRKFLAYYER-----DGVLTGVVGGGMPG--------------
MUL_0769|M.ulcerans_Agy99           VHLVEDDGRKLLAYYQR-----DGVLVGVVGGGVPG--------------
MLBr_02387|M.leprae_Br4923          KAHGMGDPSGFVK------LVADAKYGELLGGHMIGHNVSELLP------
                                         .*   ::           .    ::.  : .              

Mb0258|M.bovis_AF2122/97            AGALGVGALPDSAQICSCNNVTKGELKCAIADGCGDVPALKSCTAAGTSC
Rv0252|M.tuberculosis_H37Rv         AGALGVGALPDSAQICSCNNVTKGELKCAIADGCGDVPALKSCTAAGTSC
MMAR_0516|M.marinum_M               AGALGIGALPDSAQICSCNNVTKGELKCAIADGCADVPALKACTAAGTSC
MAV_4904|M.avium_104                T-ALGVGALPDSAQICSCNNVTKGDLKCAIADGCADVAALKSCTSAGTSC
Mvan_0297|M.vanbaalenii_PYR-1       G-GLGVGALPDGAQICSCNNVTKGALTEAIGSGCCDVPALKKCTLAGTSC
Mflv_0387|M.gilvum_PYR-GCK          ATQLGVGALPDAAQICSCNNVTKGDLTGAIAGGCCDVADLKRCTLAGTSC
MSMEG_0427|M.smegmatis_MC2_155      APGLGVGALPDIAQICSCNNVTKGDLTEAIAGGCCDVADLKKCTLAGTSC
MAB_3522c|M.abscessus_ATCC_199      GAEIGVGALPDDAQICSCNAVTKGAICAAICEGATDVPALKSATCAGTSC
TH_3739|M.thermoresistible__bu      -----------------------------------------KVMKARAKI
MUL_0769|M.ulcerans_Agy99           -----------------------------------------KVMKVRAKI
MLBr_02387|M.leprae_Br4923          -----------------------------------------ELTLAQKWD
                                                                                 .    

Mb0258|M.bovis_AF2122/97            GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFEIITATEVRTFSGLLD
Rv0252|M.tuberculosis_H37Rv         GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFEIITATEVRTFSGLLD
MMAR_0516|M.marinum_M               GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFQIISATEIRTFSGLLQ
MAV_4904|M.avium_104                GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFEIISATEIRTFSGLLE
Mvan_0297|M.vanbaalenii_PYR-1       GSCVPLLKQLLEAEGVEQSKALCEHFSQSRAELFELISATEVRTFSGLIE
Mflv_0387|M.gilvum_PYR-GCK          GSCVPLLKQLLEAEGVEQSKALCEHFSHSRAELFEIVSATSIRTFSGLIE
MSMEG_0427|M.smegmatis_MC2_155      GSCVPLLKQLLEAQGVEQSKALCEHFSQSRAELFEIISATEIRTFSGLIE
MAB_3522c|M.abscessus_ATCC_199      GSCIPMLKQILAAQGVEQSKALCEHFEQSRAELFQVVQATGIRTFSELIA
TH_3739|M.thermoresistible__bu      AAGAPISEVLE---------------------------------------
MUL_0769|M.ulcerans_Agy99           AAAVPISEMLDESQGQT----------------------------SARIP
MLBr_02387|M.leprae_Br4923          LTATELVRNVHTHPTLSEALQECFHGLIGHMINF----------------
                                     :   : . :                                        

Mb0258|M.bovis_AF2122/97            RFGRGKGCDICKPVVASILASTGSDHILDGEQASLQDSNDHFLANIQKNG
Rv0252|M.tuberculosis_H37Rv         RFGRGKGCDICKPVVASILASTGSDHILDGEQASLQDSNDHFLANIQKNG
MMAR_0516|M.marinum_M               RFGRGKGCDICKPVVASILASTGSDHILDGEQASLQDSNDHFLANIQKNG
MAV_4904|M.avium_104                RFGRGKGCDICKPVVASILASTGSEHILEGEQASLQDSNDHFLANIQKNG
Mvan_0297|M.vanbaalenii_PYR-1       RFGSGKGCDICKPVVASILASTSSTHILDGEQASLQDTNDHFLANIQRNG
Mflv_0387|M.gilvum_PYR-GCK          RFGTGKGCDICKPVVASILASTSSEHILDGEQASLQDSNDHFLANIQRNG
MSMEG_0427|M.smegmatis_MC2_155      RFGTGKGCDICKPTIASILASTSSDHILDGEQAALQDSNDHFLANIQRNG
MAB_3522c|M.abscessus_ATCC_199      KHGKGTGCDICKPTVASILASTSSDHILEGEQAGLQDTNDHFLANMQKNG
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           ARGAGPGGPLVR------------------------------WPTLTKSG
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0258|M.bovis_AF2122/97            SYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDLFGARVDQL
Rv0252|M.tuberculosis_H37Rv         SYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDLFGARVDQL
MMAR_0516|M.marinum_M               SYSVVPRVPGGDIKPEHLILIGQIAQEFGLYTKITGGQRIDMFGARVDQL
MAV_4904|M.avium_104                SYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDMFGARVDQL
Mvan_0297|M.vanbaalenii_PYR-1       SYSVVPRVPGGDITPEQLILIGEIARDFGLYTKITGGQRIDMFGARVEQL
Mflv_0387|M.gilvum_PYR-GCK          SYSVVPRVPGGDITPEHLILIGQIAKDFGLYTKITGGQRIDMFGARVDQL
MSMEG_0427|M.smegmatis_MC2_155      SYSVVPRVPGGDITPEQLILIGEIARDFGLYTKITGGQRIDMFGARVEQL
MAB_3522c|M.abscessus_ATCC_199      TYSVVPRLPGGEVTPEKLIVIGEIARDFGLYTKITGGQRIDLFGARVEQL
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           RWRAEKATASSPVARVDGIGLEPGPRRTASWPDVPGT-------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0258|M.bovis_AF2122/97            PLIWQRLVDGGMESGHAYGKAVRTVKSCVGSDWCRYGQQDSVQLAIDLEL
Rv0252|M.tuberculosis_H37Rv         PLIWQRLVDGGMESGHAYGKAVRTVKSCVGSDWCRYGQQDSVQLAIDLEL
MMAR_0516|M.marinum_M               PLIWKRLVDAGMESGHAYGKALRTVKSCVGSDWCRYGQQDSVQLAIDLEL
MAV_4904|M.avium_104                PAIWKRLVDGGMESGHAYGKALRTVKSCVGTDWCRYGQQDSVQLAIDLEL
Mvan_0297|M.vanbaalenii_PYR-1       PEIWRRLVEGGMESGHAYGKSLRTVKSCVGSDWCRYGQQDSVQMAINLEL
Mflv_0387|M.gilvum_PYR-GCK          PEIWRRLVEGGMESGQAYGKSLRTVKSCVGSDWCRYGQQDSVQMAINLEL
MSMEG_0427|M.smegmatis_MC2_155      PEIWRRLVEGGMESGHAYGKSLRTVKSCVGSDWCRYGQQDSVQMAINLEL
MAB_3522c|M.abscessus_ATCC_199      PLIWKRLIDAGMESGHAYGKSLRTVKSCVGSTWCRYGVQDSVAMAVELEL
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0258|M.bovis_AF2122/97            RYRGLRAPHKIKLGVSGCARECAEARGKDVGVIATEKGWNLYVAGNGGMT
Rv0252|M.tuberculosis_H37Rv         RYRGLRAPHKIKLGVSGCARECAEARGKDVGVIATEKGWNLYVAGNGGMT
MMAR_0516|M.marinum_M               RYRGLRAPHKIKLGVSGCARECAEARSKDVGVIATEKGWNLYVGGNGGMT
MAV_4904|M.avium_104                RYRGLRAPHKIKMGVSGCARECAEARSKDVGVIATEKGWNLYVGGNGGMT
Mvan_0297|M.vanbaalenii_PYR-1       RYRGLRAPHKIKMGVSGCARECAEARGKDVGVIATETGWNLYVGGNGGMT
Mflv_0387|M.gilvum_PYR-GCK          RYRGLRAPHKIKMGVSGCARECAEARGKDVGVIATETGWNLYIGGNGGMT
MSMEG_0427|M.smegmatis_MC2_155      RYRGLRAPHKIKMGVSGCARECAEARGKDVGVIATDSGWNLYVGGNGGMT
MAB_3522c|M.abscessus_ATCC_199      RYRGLRSPHKLKMGVSGCARECAEARGKDVGVIATENGWNLYVGGNGGAT
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0258|M.bovis_AF2122/97            PKHAQLLASDLDKETLIRYIDRFLIYYIRTADRLQRTAPWVESLG--LDH
Rv0252|M.tuberculosis_H37Rv         PKHAQLLASDLDKETLIRYIDRFLIYYIRTADRLQRTAPWVESLG--LDH
MMAR_0516|M.marinum_M               PKHAQLLASDLDTETLVRYIDRFLMYYVRTADRLQRTAPWVESLEGGLDH
MAV_4904|M.avium_104                PKHAQLLASDLDTETLVRYIDRFVMYYIRTADRLQRTAPWVESLDGGLDH
Mvan_0297|M.vanbaalenii_PYR-1       PRHAELLAGDLDDETLIRYIDRFLMFYIRTADRLQRTAPWVEQVG--LEH
Mflv_0387|M.gilvum_PYR-GCK          PKHAQLLAGDLDDETLVRYIDRFLMFYIRTADRLQRTAPWVEQLG--LEH
MSMEG_0427|M.smegmatis_MC2_155      PRHAQLLAGDLDDETLIRYIDRFLMFYIRTADRLQRTAPWVEALDGGIDH
MAB_3522c|M.abscessus_ATCC_199      PAHAKLLAGDLDSETLIRYIDRYLMFYIRTADRLQRTAPWQEAIEGGLDH
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0258|M.bovis_AF2122/97            VREVVCEDSLGLAEEFEAAMQRHVANYKCEWKGVLEDPDKLSRFVSFVNA
Rv0252|M.tuberculosis_H37Rv         VREVVCEDSLGLAEEFEAAMQRHVANYKCEWKGVLEDPDKLSRFVSFVNA
MMAR_0516|M.marinum_M               VREVVCDDSLGLAEEFEAAVQHHIANYKCEWKGVLEDPDKLSRFVSFVNA
MAV_4904|M.avium_104                VREVVCEDSLGLAEEFEAAMERHVRNYKCEWKGVLDDPDKLSRFVSFVNA
Mvan_0297|M.vanbaalenii_PYR-1       LREVVCEDSLGLAEEFEAAIARHVEGYACEWKGVLSDPDKLSRFVSFVNA
Mflv_0387|M.gilvum_PYR-GCK          LREVICDDSLGLAAEFEAAVQRHVDGYACEWKGVLEDPDKLSRFVSFVNA
MSMEG_0427|M.smegmatis_MC2_155      LRDVVCDDSLGLAEEFEAAMARHVEGYACEWKGVLQDPDKLARFVSFVNA
MAB_3522c|M.abscessus_ATCC_199      IRAVVCEDSLGIADELEAAMARHVQGYQDEWAAVLADPDKLRRFVSFVNA
TH_3739|M.thermoresistible__bu      --------------------------------------------------
MUL_0769|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02387|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0258|M.bovis_AF2122/97            PDAVDSTVTFTERAGRKVP----VSIGIPRVRS------
Rv0252|M.tuberculosis_H37Rv         PDAVDSTVTFTERAGRKVP----VSIGIPRVRS------
MMAR_0516|M.marinum_M               PDAADPTVAFTERAGRKVP----VSIGIPRVRS------
MAV_4904|M.avium_104                PDAVDSTVAFTEHAGRKIP----VSIGMPKIRQG-----
Mvan_0297|M.vanbaalenii_PYR-1       PDVPDPTVTFTENAGRMVP--APVSIGMPKIGR------
Mflv_0387|M.gilvum_PYR-GCK          PDVPDPTIEFTEIAGRKVP--SPVAIGMPKVGR------
MSMEG_0427|M.smegmatis_MC2_155      PDTPDPTVSFTERSGRKVPDLRPVSIGMPTIRPLQEMS-
MAB_3522c|M.abscessus_ATCC_199      PDQPDSTIAFDESGPRKVP----VLLGTPGFRAAAEAAT
TH_3739|M.thermoresistible__bu      ---------------------------------------
MUL_0769|M.ulcerans_Agy99           ---------------------------------------
MLBr_02387|M.leprae_Br4923          ---------------------------------------