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VAFDAAMSTHEDLLATIRYVRDRTGDPNAWQTGLTPTEVTAVVTSTTRSEQLDAILRKIRQRHSNLYYPA PPDREQGDAARAIADAEAALAHQNSATAQLDLQVVSAILNAHLKTVEGGESLHELQQEIEAAVRIRSDLD TPAGARDFQRFLIGKLKDIREVVATASLDAASKSALMAAWTSLYDASKGDRGDADDRGPASVGSGGAPAR GAGQQPELPTRAEPDCLLDSLLLEDPGLLADDLQVPGGTSAAIPSASSTPSLPNLGGATMPGGGATPALV PGVSAPGGLPLSGLLRGVGDEPELTDFDERGQEVRDPADYEHSNEPDERRADDREGADEDAGLGKSESPP QAPTTVTLPNGETVTAASPQLAAAIKAAASGTPIADAFQQQGIAIPLPGTAVANPVDPARISAGDVGVFT ATPLPLALAKLFWTARFNTSQPCEGQTF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0026 | - | - | 100% (448) | hypothetical protein Rv0026 |
| M. tuberculosis H37Rv | Rv0025 | - | 1e-10 | 33.04% (112) | hypothetical protein Rv0025 |
| M. tuberculosis H37Rv | Rv0739 | - | 2e-08 | 36.27% (102) | hypothetical protein Rv0739 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0027 | - | 0.0 | 99.76% (420) | hypothetical protein Mb0027 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0045 | - | 8e-89 | 53.52% (355) | hypothetical protein MMAR_0045 |
| M. avium 104 | MAV_0044 | - | 1e-123 | 56.29% (437) | hypothetical protein MAV_0044 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3514 | - | 4e-07 | 24.64% (414) | PUTATIVE putative hypothetical protein Mflv_4945 |
| M. ulcerans Agy99 | MUL_0044 | - | 9e-87 | 52.96% (355) | hypothetical protein MUL_0044 |
| M. vanbaalenii PYR-1 | Mvan_3258 | - | 9e-05 | 25.64% (195) | hypothetical protein Mvan_3258 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0026|M.tuberculosis_H37Rv --------------------------------------------------
Mb0027|M.bovis_AF2122/97 --------------------------------------------------
MAV_0044|M.avium_104 --------------------------------------------------
MMAR_0045|M.marinum_M --------------------------------------------------
MUL_0044|M.ulcerans_Agy99 --------------------------------------------------
TH_3514|M.thermoresistible__bu -------------------------------------VTGGLDVAARLAD
Mvan_3258|M.vanbaalenii_PYR-1 MPAVGGSAGSYGRLIVTPDMEPPDAGHWDAQEQTYRVGATTWDGIHQKIV
Rv0026|M.tuberculosis_H37Rv -----MAFDAAMSTHEDLLATIRYVRDRTGDPNAWQTGLTPTEVTAVVTS
Mb0027|M.bovis_AF2122/97 -----MAFDAAMSTHEDLLATIRYVRDRTGDPNAWQTGLTPTEVTAVVTS
MAV_0044|M.avium_104 -----------MSAYDDLLAAVKDVRDRTGDPNAWQTGLAPAEVSAVITP
MMAR_0045|M.marinum_M -----------MGGSE--------QRAQSG--------------------
MUL_0044|M.ulcerans_Agy99 -----------MGGSE--------QRAQSG--------------------
TH_3514|M.thermoresistible__bu GLPAVRAAQEYLSACESLGYRQPDLSGRPGQVFDWYRSEDGLDLGALADD
Mvan_3258|M.vanbaalenii_PYR-1 TDNAEFRDAADSQGFDEAHRAGAVLAEEAKTIAEWHDKCANKCADIATVL
: ..
Rv0026|M.tuberculosis_H37Rv TTRSEQLDAILRKIRQRHSNLYYPAP-------------PDREQGDAARA
Mb0027|M.bovis_AF2122/97 TTRSEQLDAILRKIRQRHSNLYYPAP-------------PDREQGDAARA
MAV_0044|M.avium_104 STRPEQLQAILAKIRRQHAEVFGAAPTGVARPPADAGPAPDRESGAAADA
MMAR_0045|M.marinum_M -----------------------------------------AARGAAADA
MUL_0044|M.ulcerans_Agy99 -----------------------------------------AAGGAAADA
TH_3514|M.thermoresistible__bu SAALDRAAARAAEVLELQDRQSAALGAGWRGVGGTAAAELLRRHGAASAA
Mvan_3258|M.vanbaalenii_PYR-1 RDTRAGQEQLVREADAKIASAKLPGEAEALVTQYHGIARYQTEAGVTAAM
* ::
Rv0026|M.tuberculosis_H37Rv IADAEAALAHQNSATAQLDLQVVSAILNAHLKTVEGGES-----------
Mb0027|M.bovis_AF2122/97 IADAEAALAHPNSATAQLDLQVVSAILNAHLKTVEGGES-----------
MAV_0044|M.avium_104 IASAEAALAQQNSVSSQLDMQVVTAILNAHLKAVDGREA-----------
MMAR_0045|M.marinum_M IAGAEVALAHQNSMSSQLDLQVIAAILNAHLTAVDGSEA-----------
MUL_0044|M.ulcerans_Agy99 IAGAKVALAHQNSMSSQLDLQVIAAILNAHLTAVDGSEA-----------
TH_3514|M.thermoresistible__bu ATAALRTAADALTTLRTELWQLVDRKVTATQGIDGGGRT-----------
Mvan_3258|M.vanbaalenii_PYR-1 ASHTAFKASTENTRALDLLTKWGDAPTAPPVQPVDHTSPGIEQDENPYSD
: : : : : . .
Rv0026|M.tuberculosis_H37Rv -------------LHELQQEIEAAVRIRSDLDTPAGARDFQRFLIGKLKD
Mb0027|M.bovis_AF2122/97 -------------LHELQQEIEAAVRIRSDLDTPAGARDFQRFLIGKLKD
MAV_0044|M.avium_104 -------------LTKLQQETEAAVRTRSDLDTPAGARDFQRFLIGKLRD
MMAR_0045|M.marinum_M -------------LDELQQETEAAVRTRSDLDTPAGARDFQRFLIGKLRD
MUL_0044|M.ulcerans_Agy99 -------------LDELQQETEAAVRTRSDLDTLAGARDFQRFLIGKLRD
TH_3514|M.thermoresistible__bu -------------DWQAAAHTVLTGAGDRSVASELVDAEVKPFVDEAIGC
Mvan_3258|M.vanbaalenii_PYR-1 TEKREAGADAPKPVDDAPTDPAGTSTTQPGVSPGSKSAAGDESIKAATGP
. . : .: . . :
Rv0026|M.tuberculosis_H37Rv IREVVATASLDAASKSALMAAWTSLYDASKGDRGDADDRGPASVGSGGAP
Mb0027|M.bovis_AF2122/97 IREVVATASLDAASKSALMAAWTSLYDASKGDRGDADDRGPASVGSGGAP
MAV_0044|M.avium_104 IRAVVLNASLDDTSKSALMAAWTSLYDAAKNDR--PGDHASSAGAAADAA
MMAR_0045|M.marinum_M IREVVATASLDDTSKATLMAAWTSLYNASKQEASSPGDVPTATEPAAGTG
MUL_0044|M.ulcerans_Agy99 IREVVATASLDDTSKATLMAAWTSLYNASKQEASSPGDAQTATEPAAGTG
TH_3514|M.thermoresistible__bu EWLTVMNQTLTSIEEKFDAAIAELTGSAAVPDFGAGEGEAPPWAANWGPP
Mvan_3258|M.vanbaalenii_PYR-1 VTQPTPGVTSSPAASALGGAGMPSMGGIGGGGMGSGGGIPKMPGGLGSGG
. : . * . . . .
Rv0026|M.tuberculosis_H37Rv ARGAGQQPEL----------------------------------------
Mb0027|M.bovis_AF2122/97 ARGAGQQPEL----------------------------------------
MAV_0044|M.avium_104 AAGTSDQPDE----------------------------------------
MMAR_0045|M.marinum_M ADAVRAAG------------------------------------------
MUL_0044|M.ulcerans_Agy99 PDADRAAG------------------------------------------
TH_3514|M.thermoresistible__bu WAANWGQPGA----------------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 MPGMGSNPLSGGVGQMPGAASGLPNPGAVPGAGSASPLSSAFNQGMATTA
.
Rv0026|M.tuberculosis_H37Rv ------PTRAEPDCLLDSLLLEDPGLLAD---DLQVPGG-TSAAIPSASS
Mb0027|M.bovis_AF2122/97 ------PTRAEPDCLLDSLLLEDPGLLAD---DLQVPGG-TSAAIPSASS
MAV_0044|M.avium_104 ------DLDDEWDPLLDSLLADDDGSPIDPAAALDPLGGNTIPPAPPPAM
MMAR_0045|M.marinum_M --------LTSGDPLLDSLLFDDPGLVAE----APLPQGAAPSGAATAPA
MUL_0044|M.ulcerans_Agy99 --------LISGDPLLDSLLFDDPGLVDE----ATLPQGAAPSGAATAPS
TH_3514|M.thermoresistible__bu ------ASWGSP-PVADGAASAIGADPAP---AEAAAPGVPPPAVPPTGP
Mvan_3258|M.vanbaalenii_PYR-1 GMGGGIPSAPPPAPASPSPALSAGGGHAAPPVSAAPGGGVSPAGAQAGMV
. . * . . .
Rv0026|M.tuberculosis_H37Rv TPSLPNLGGATMPGGG-------------------------ATPALVPGV
Mb0027|M.bovis_AF2122/97 TPSLPNLGGATMPGGG-------------------------ATPALVPGV
MAV_0044|M.avium_104 APALPSFGGGSLPGLG-------------------------ATPASMSGW
MMAR_0045|M.marinum_M LPSMPSLGDGSGAATP-------------------------SGAGSVP--
MUL_0044|M.ulcerans_Agy99 LPSMPSLGDGSGAATP-------------------------SGAGSVP--
TH_3514|M.thermoresistible__bu GGGLPDPGAGLSTVGR-------------------------QLVDLLGGL
Mvan_3258|M.vanbaalenii_PYR-1 SPATPAAAAPTGAGIGGGGAPMMLPPGSMGPPAGAPPPAPTVPAGTVGST
. * . . :
Rv0026|M.tuberculosis_H37Rv SAPGGLPLSGLLRGVGDEP-ELTDFDERGQEVRD----PADYEHSNEPDE
Mb0027|M.bovis_AF2122/97 SAPGGLPLSGLLRGVGDEP-ELTDFDERGQEVRD----PADYEHSNEPDE
MAV_0044|M.avium_104 ETPGGLPLSGLQAGDASDP-ALQDLADEDLPEDQ----GQQHDSPADGSA
MMAR_0045|M.marinum_M NLPAGPALSAIPRAIASRLDELDDPSLDSLALDP----DDSDDEPADLDE
MUL_0044|M.ulcerans_Agy99 NLPAGPALSAIPRAIASRLDELDDPSLDSLALDPDASGDDSDDEPADLDE
TH_3514|M.thermoresistible__bu LGPVGEALGNGVGAAGVDPMGGEDAGGEDAGTEERDGASDADTDAEDDDR
Mvan_3258|M.vanbaalenii_PYR-1 NAPAAPAPSAASAAAGPTLIPASVVAAGQTAAARERRESADAAAAKELVW
* . . . . . . :
Rv0026|M.tuberculosis_H37Rv RRADDREGADEDAG---LGKSESPPQAPTTVTLPNGETVTAASPQLAAAI
Mb0027|M.bovis_AF2122/97 RRADDREGADEDAG---LGKSESPPQAPTTVTLPNGETVTAASPQLAAAI
MAV_0044|M.avium_104 EQADD-ENASADE----------PPAGPTSVTLPDGETVTAASPQLAAAI
MMAR_0045|M.marinum_M DTDGGGEDTEQPAS---SGEPQPLPTGPTTVTLPNGDTITAASPELAAAI
MUL_0044|M.ulcerans_Agy99 DTDGGGEDTEQPAS---SGEPQPLPTGPTTVTLPNGDTITAASPELAAAI
TH_3514|M.thermoresistible__bu GDDTPEDDTPDDGD---PDAGGSPGEDPQEAPDPEHDPDPAPGEPETHXX
Mvan_3258|M.vanbaalenii_PYR-1 KLQHAAYVALNPAAGWAVGVFRSPSGTETVITSNDGSSYIPAGVFVPRSV
: . : .. ... .
Rv0026|M.tuberculosis_H37Rv KAAASGTPIADAFQQ-----------------------------------
Mb0027|M.bovis_AF2122/97 KAAASGTPIADAFQQ-----------------------------------
MAV_0044|M.avium_104 KAAVAGTPIAEAFQQ-----------------------------------
MMAR_0045|M.marinum_M NATAGGAAIADAFQQ-----------------------------------
MUL_0044|M.ulcerans_Agy99 NAAAGGAAIADAFQQ-----------------------------------
TH_3514|M.thermoresistible__bu XAGPGDVAIDFSGST-----------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 RVLATDPLVDDSFRQRWFGWGDPARVLVEYAQLRAQWGWKLVAAATTAGV
. . : :
Rv0026|M.tuberculosis_H37Rv -----------------------QGIAIPLPGTAVA--------------
Mb0027|M.bovis_AF2122/97 -----------------------QGIAIPLPGTAVA--------------
MAV_0044|M.avium_104 -----------------------QGMTLPAPGTAVA--------------
MMAR_0045|M.marinum_M -----------------------QGIAIPPPGTPVS--------------
MUL_0044|M.ulcerans_Agy99 -----------------------QGIAIPPPGTPVS--------------
TH_3514|M.thermoresistible__bu -----------------------EALGEALDRLDVGGVL-----------
Mvan_3258|M.vanbaalenii_PYR-1 SVLRDAGVEHPPSCSGDTNPLLQQGVDVPAPVLDDMHIHRLAVLWPEVYP
:.: .
Rv0026|M.tuberculosis_H37Rv --------NPVDPARISAGDVGVFTA-TPLPLALAKLFWTARFNTSQPCE
Mb0027|M.bovis_AF2122/97 --------NPVDPARISAGDVGVFTDRHALALGPSKALLDGQIQHISAVR
MAV_0044|M.avium_104 --------NPVDVVRVSPGDIGMFTDRHALALGPGKALLDGQIQHIATVS
MMAR_0045|M.marinum_M --------DPIDPARLAAGDIGMFTDRHALALGDGNAFLDGQMQQVSSIG
MUL_0044|M.ulcerans_Agy99 --------DPIDPARLAAGDIGMFRDWHALALGDGNAFLDGQIQQVSSIG
TH_3514|M.thermoresistible__bu -----VLAGSVSPAPALPVDPELIVRRWLTLTGVHNYEPQHLRDAVAFLR
Mvan_3258|M.vanbaalenii_PYR-1 RLLRIMDADPLCQDRIVSAVTAAMINAATTQAQVIDGGIDEALRLVWAVR
..: . : .
Rv0026|M.tuberculosis_H37Rv G----QTF------------------------------------------
Mb0027|M.bovis_AF2122/97 G----RNFLGWIHP---AATATAPARTEAPTPTRPAAAR-----------
MAV_0044|M.avium_104 G----PSFLGWEHPPAAAASVTAPAKPDPPTPTRPASSSTT---------
MMAR_0045|M.marinum_M G----PNFLGWQHPP-TSTTVTAPAQTGAPTPTRPATTPVAPRY------
MUL_0044|M.ulcerans_Agy99 G----PNFLGWQHPP-TSTTVTEPAQTGAPTPTRPATTPVAPRY------
TH_3514|M.thermoresistible__bu HS---RDRFDWPALVDDPVGLDDIAAALMPAPTGRLRKAVSPGLPPRTAA
Mvan_3258|M.vanbaalenii_PYR-1 GSDREPTVQQWADYDKAAKALNVMTAMRRPAFATNTGAVADPSDTTEFLA
Rv0026|M.tuberculosis_H37Rv --------------------------------------------------
Mb0027|M.bovis_AF2122/97 --------------------------------------------------
MAV_0044|M.avium_104 --------------------------------------------------
MMAR_0045|M.marinum_M --------------------------------------------------
MUL_0044|M.ulcerans_Agy99 --------------------------------------------------
TH_3514|M.thermoresistible__bu RNSPGSRPPDS---------------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 DYRAHWLVARTAEHIGGWSRRPLPLPDMCYAAAATGDPDLRDMIVKALVS
Rv0026|M.tuberculosis_H37Rv -----------
Mb0027|M.bovis_AF2122/97 -----------
MAV_0044|M.avium_104 -----------
MMAR_0045|M.marinum_M -----------
MUL_0044|M.ulcerans_Agy99 -----------
TH_3514|M.thermoresistible__bu -----------
Mvan_3258|M.vanbaalenii_PYR-1 VEEDLQYEAPR