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PAVGGSAGSYGRLIVTPDMEPPDAGHWDAQEQTYRVGATTWDGIHQKIVTDNAEFRDAADSQGFDEAHRA GAVLAEEAKTIAEWHDKCANKCADIATVLRDTRAGQEQLVREADAKIASAKLPGEAEALVTQYHGIARYQ TEAGVTAAMASHTAFKASTENTRALDLLTKWGDAPTAPPVQPVDHTSPGIEQDENPYSDTEKREAGADAP KPVDDAPTDPAGTSTTQPGVSPGSKSAAGDESIKAATGPVTQPTPGVTSSPAASALGGAGMPSMGGIGGG GMGSGGGIPKMPGGLGSGGMPGMGSNPLSGGVGQMPGAASGLPNPGAVPGAGSASPLSSAFNQGMATTAG MGGGIPSAPPPAPASPSPALSAGGGHAAPPVSAAPGGGVSPAGAQAGMVSPATPAAAAPTGAGIGGGGAP MMLPPGSMGPPAGAPPPAPTVPAGTVGSTNAPAAPAPSAASAAAGPTLIPASVVAAGQTAAARERRESAD AAAAKELVWKLQHAAYVALNPAAGWAVGVFRSPSGTETVITSNDGSSYIPAGVFVPRSVRVLATDPLVDD SFRQRWFGWGDPARVLVEYAQLRAQWGWKLVAAATTAGVSVLRDAGVEHPPSCSGDTNPLLQQGVDVPAP VLDDMHIHRLAVLWPEVYPRLLRIMDADPLCQDRIVSAVTAAMINAATTQAQVIDGGIDEALRLVWAVRG SDREPTVQQWADYDKAAKALNVMTAMRRPAFATNTGAVADPSDTTEFLADYRAHWLVARTAEHIGGWSRR PLPLPDMCYAAAATGDPDLRDMIVKALVSVEEDLQYEAPR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3258 | - | - | 100% (811) | hypothetical protein Mvan_3258 |
M. vanbaalenii PYR-1 | Mvan_3736 | - | 0.0 | 72.77% (819) | hypothetical protein Mvan_3736 |
M. vanbaalenii PYR-1 | Mvan_0085 | - | 1e-30 | 30.90% (411) | hypothetical protein Mvan_0085 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2108 | - | 6e-18 | 23.86% (591) | hypothetical protein Mb2108 |
M. gilvum PYR-GCK | Mflv_2790 | - | 0.0 | 73.02% (819) | hypothetical protein Mflv_2790 |
M. tuberculosis H37Rv | Rv2082 | - | 6e-18 | 23.86% (591) | hypothetical protein Rv2082 |
M. leprae Br4923 | MLBr_01556 | infB | 8e-11 | 27.09% (299) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_1830 | - | 2e-17 | 27.13% (376) | hypothetical protein MAB_1830 |
M. marinum M | MMAR_1405 | - | 2e-24 | 29.38% (405) | hypothetical protein MMAR_1405 |
M. avium 104 | MAV_2415 | - | 5e-16 | 31.03% (232) | hypothetical protein MAV_2415 |
M. smegmatis MC2 155 | MSMEG_0071 | - | 1e-22 | 26.68% (581) | hypothetical protein MSMEG_0071 |
M. thermoresistible (build 8) | TH_4387 | - | 1e-11 | 29.22% (219) | PUTATIVE putative PPE family protein |
M. ulcerans Agy99 | MUL_0572 | - | 6e-17 | 31.46% (267) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_3258|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2790|M.gilvum_PYR-GCK -------------------------------------------------- Mb2108|M.bovis_AF2122/97 -------------------------------------------------- Rv2082|M.tuberculosis_H37Rv -------------------------------------------------- TH_4387|M.thermoresistible__bu -------------------------------------------------- MAB_1830|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 -------------------------------------------MSYVVAI MAV_2415|M.avium_104 MAPLAVDPEAMYAAGSAVAAIGDSLAANLTILTAGVSAHTGVDRAGEVFG MMAR_1405|M.marinum_M -------------------------------------------------- MSMEG_0071|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mvan_3258|M.vanbaalenii_PYR-1 ------------------MPAVGGSAGSYGRLIVTPDMEP-----PDAGH Mflv_2790|M.gilvum_PYR-GCK -------------MRVQLMPAVGGSAGSYGRLIVTPDMEP-----PDAGH Mb2108|M.bovis_AF2122/97 -------------MAGDLPPGRWSALLVGAWWPARPDAPM-----AGVTY Rv2082|M.tuberculosis_H37Rv -------------MAGDLPPGRWSALLVGAWWPARPDAPM-----AGVTY TH_4387|M.thermoresistible__bu -------------------------------MGIMPDTSP-----YGG-- MAB_1830|M.abscessus_ATCC_1997 --------------------------MADDGWQSRSHADI-----VGKLG MUL_0572|M.ulcerans_Agy99 PDMLASAAADVAGIGSSVGAANTAAVGATTGVMAAADDEVSVAIAALFSG MAV_2415|M.avium_104 LGYQDSAESMLKAAAGVVNACRKCGALIQQGASNYSAAEAASTLGGGSGA MMAR_1405|M.marinum_M -------------MPPKPTSPHASEILQNYWEETLEPADLMR---RSVEM MSMEG_0071|M.smegmatis_MC2_155 --------MMGLGKLEKPKGGHFDRMVGPGAWPETEESEFS----NRQAE MLBr_01556|M.leprae_Br4923 MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES Mvan_3258|M.vanbaalenii_PYR-1 WDAQEQTYRVGATTWDGIHQKIVTDNA---EFRDAADSQGFDEAHRAGAV Mflv_2790|M.gilvum_PYR-GCK WDDQEQTYRAGATSWDGIHQQIVTDSA---RFREAADSQGFDEVHRVNAV Mb2108|M.bovis_AF2122/97 WRKAAQLKRNEANDLRNERSLLAVNQG---RTADDLLERYWRGEQRL-AT Rv2082|M.tuberculosis_H37Rv WRKAAQLKRNEANDLRNERSLLAVNQG---RTADDLLERYWRGEQRL-AT TH_4387|M.thermoresistible__bu -------QTVTGPGWPNVDEDALGAAA---AAYEALAAK----------- MAB_1830|M.abscessus_ATCC_1997 ALKADNAFTLAN-TWSDVYTKLSDAAV---SYGNAKSKLAEP-------- MUL_0572|M.ulcerans_Agy99 HGQAYQAISAQAAAFHDQFLRALTGAGGAYAAAEAANASPLQAAEQEVLA MAV_2415|M.avium_104 LPAPSAPADLAAPGPPGTWGKGEPPPLLWAVIQALVSEVWPDGDEAGLHA MMAR_1405|M.marinum_M TKLSGQLIAASEDGQVAAIRLLNHGQGDLADVISTAWTKYFVTVGLVGAQ MSMEG_0071|M.smegmatis_MC2_155 ILGIRQRLTGAKESWQTHQSYLDSEATWAGTSARAANARVEQHTKSMVAH MLBr_01556|M.leprae_Br4923 FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP Mvan_3258|M.vanbaalenii_PYR-1 LAEEAKTIAEWHDKCANKCADIATVLRDTR-AGQEQLVREADAKIASAKL Mflv_2790|M.gilvum_PYR-GCK LAEEAKTIAEWHAKVADKCGDIATVLRETR-SGQEQVVREADAKIASAKL Mb2108|M.bovis_AF2122/97 IAHQCEVKSDQSEQVADAVNYLRDRLTEIAQSGNQQINQILAGKGPIEAK Rv2082|M.tuberculosis_H37Rv IAHQCEVKSDQSEQVADAVNYLRDRLTEIAQSGNQQINQILAGKGPIEAK TH_4387|M.thermoresistible__bu ---------------------LTGTVVPQQQGQMMQLSDTWEGSGATAAV MAB_1830|M.abscessus_ATCC_1997 -------------------DFWTGKGPEAALDEMTTKERELTSESGTSAK MUL_0572|M.ulcerans_Agy99 VINAPTNALLGRPLIGNGTDGLAGTGAAGGAGGLLWGNGGNGGSGAAGQA MAV_2415|M.avium_104 AASRWHGFAAAMNGVQGTLNASKALFDSQQIPEGEKIDHALAEIGAAAAA MMAR_1405|M.marinum_M VGQAGAYLSAWANALGAMLAEMSGVVDWTESAITALEASRPAVEAAGQDV MSMEG_0071|M.smegmatis_MC2_155 EHQLEKVEKWCGEAIGLIGTVKEAIIGTVNSAVEAINEAAADADKNETDA MLBr_01556|M.leprae_Br4923 VQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA Mvan_3258|M.vanbaalenii_PYR-1 PGEAEALVTQ---------------------------------------- Mflv_2790|M.gilvum_PYR-GCK PGEVETLVTQ---------------------------------------- Mb2108|M.bovis_AF2122/97 VAAVNAVIEQ---------------------------------------- Rv2082|M.tuberculosis_H37Rv VAAVNAVIEQ---------------------------------------- TH_4387|M.thermoresistible__bu GEASTIIAGH---------------------------------------- MAB_1830|M.abscessus_ATCC_1997 AGKMSTALFQ---------------------------------------- MUL_0572|M.ulcerans_Agy99 GGAGGAAGLIGTGGAGGMGGAGGGAGGMGGSGGWLLGNG----------- MAV_2415|M.avium_104 IGQQCDALARTVDEFADRVGHAQQAIRDLLHRIEALGDIGHDIMLIIDGD MMAR_1405|M.marinum_M DQLIEQIKTEAQSQIAAIS------------------------------- MSMEG_0071|M.smegmatis_MC2_155 SSKIEKIKD----------------------------------------- MLBr_01556|M.leprae_Br4923 PHPGHPGMPTG--------------------------------------- Mvan_3258|M.vanbaalenii_PYR-1 --------------------YHGIARYQTEAGVTAAMASHTAFKASTENT Mflv_2790|M.gilvum_PYR-GCK --------------------YHGIARYRTEAGVTAAMASHTSFKRSTENT Mb2108|M.bovis_AF2122/97 --------------------SNAMADHVGATAMSNIIDATQRVFDETIGG Rv2082|M.tuberculosis_H37Rv --------------------SNAMADHVGATAMSNIIDATQRVFDETIGG TH_4387|M.thermoresistible__bu --------------------EANAAHAAAIAAKLRSMEAAVIKAKTMANA MAB_1830|M.abscessus_ATCC_1997 --------------------DGEVLSQSSRVAQAYPVPPDDTDADSKK-- MUL_0572|M.ulcerans_Agy99 ----------------GAGGAGGVGCAGVSGGVGGTGGNAMLFGNGGAGG MAV_2415|M.avium_104 AWDEIQKIARDVNAVLQHLGQEARAFEQEIRLLMQAADREIVTCQKYARR MMAR_1405|M.marinum_M --------------------SAAMGVLAAVPSWAASIPVSMSIPHSGIQG MSMEG_0071|M.smegmatis_MC2_155 ---------------------LAYDFNKSIVQWGADTVQGKEDIPSEPPK MLBr_01556|M.leprae_Br4923 -----------------PHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPR Mvan_3258|M.vanbaalenii_PYR-1 RALDLLTKWGDAPTAPPVQPVDHTSPGIEQDENPYSDTEKREAGADAPKP Mflv_2790|M.gilvum_PYR-GCK RALDLLTRWGDALAAPPVQPLDSPSPGIAQGDNNPKKAPPQEEDSSKSTP Mb2108|M.bovis_AF2122/97 DAHTWLRDHGVSLDAPARPRPVTAEDMTSMTANSPAGSPFGAAPSAPSHS Rv2082|M.tuberculosis_H37Rv DAHTWLRDHGVSLDTPARPRPVTAEDMTSMTANSPAGSPFGAAPSAPSHS TH_4387|M.thermoresistible__bu VAVETQRECEAIAAAPFPNRQELLQSRIAMGLAQNVG------------- MAB_1830|M.abscessus_ATCC_1997 ---KLLEAVRAEAQRLYTSPLEADRPKFTEDSNTTASGPMPAGPGGNN-- MUL_0572|M.ulcerans_Agy99 MGGAGADGAVGAAGTAGTSTSAGGVGGAGWDATAAGVLAATGGDGGDSGG MAV_2415|M.avium_104 GLITFLGEDVGNPVATALDFGINVQEGVVKGAVGMGLGLVDLSPHWIALD MMAR_1405|M.marinum_M PCPATTTGTDGTPTGGVTGPGQGAPPGRSAGGVIGPGQVGSAAPLGNAGG MSMEG_0071|M.smegmatis_MC2_155 LPKDIFKNVEPATGSQDGEIRDGQADVLFMNSSLGGDASDVRASVKPSRP MLBr_01556|M.leprae_Br4923 PPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSD Mvan_3258|M.vanbaalenii_PYR-1 VDD---------APTDPAGTS----TTQPGVSPGSKSAAGDESIKAATGP Mflv_2790|M.gilvum_PYR-GCK LQEGSDQSPPAMSPTDSAGTS----TTQP----GIKSVTSDEGIKVATGP Mb2108|M.bovis_AF2122/97 TTTSG--PPTAPTPTSPFGTAPMVLSSSSTSSGPPTAPTPTSPFGTAPMP Rv2082|M.tuberculosis_H37Rv TTTSG--PPTAPTPTSPFGTAPMVLSSSSTSSGPPTAPTPTSPFGTAPMP TH_4387|M.thermoresistible__bu ----------------------------------QVTASSTELANTLGVP MAB_1830|M.abscessus_ATCC_1997 ---------------------------------GGGGGSGSGGSGSGTQT MUL_0572|M.ulcerans_Agy99 GGAGGNGGAGGAGGHGSALFGADGANGNGGAGGAGGNPGAPGNGGTGGVG MAV_2415|M.avium_104 PEGAGATWGGLVKNAWKESFVNAAVNPQEFAQARLQELKGLVHADDWTRD MMAR_1405|M.marinum_M VKGPG---SGGDPVPGQAGSVTGPGQASTAPAALNSGPAGGVLGPASGTS MSMEG_0071|M.smegmatis_MC2_155 VDTWE----QDNVGLGEDASGVRPTPAIEPPVEQVEPVNSGLGGEQPDIR MLBr_01556|M.leprae_Br4923 AGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRP Mvan_3258|M.vanbaalenii_PYR-1 VTQPTPG-VTSS-PAASAL--GGAGMPSMG-GIGGGGMGSGGGIPKMPGG Mflv_2790|M.gilvum_PYR-GCK L-QPTPG-VASPGAGASPL--GGGGMSSMG-GMVGGGMGSGG-APKLPGG Mb2108|M.bovis_AF2122/97 PGPPPPGTVSPPLPPSAPA--VGVGGPSVP-AAGMPPAAAAATAPLSPQS Rv2082|M.tuberculosis_H37Rv PGPPPPGTVSPPLPPSAPA--VGVGGPSVP-AAGMPPAAAAATAPLSPQS TH_4387|M.thermoresistible__bu PTIPTAG-------GAPAA--GAPGQEAAG-DAAQQAAQLAGMAAQIPAQ MAB_1830|M.abscessus_ATCC_1997 PPSSSDGLASKDTKPQLAG--GEGQQAGAGQGQGGQGSGSGGGTPGGGQG MUL_0572|M.ulcerans_Agy99 PDAATSGGMGGTGGDPGAV--GGRGNSGAAGGAGAVAGASGAAGTIIAGN MAV_2415|M.avium_104 RPGLGAGEVAFDAATLIAPGLGEAGAAADGASAAARGAEAEADAAGAAGR MMAR_1405|M.marinum_M SSAPKAGGVSGGSVSGSSGASTSASPPVQAHSTATPTSGTPSTTTGHSNS MSMEG_0071|M.smegmatis_MC2_155 PAPPIPQPVLGRPPSAPAPTAGGPSGPGSAISPSAPTPVSSSGPPTGGGG MLBr_01556|M.leprae_Br4923 GGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDF . . Mvan_3258|M.vanbaalenii_PYR-1 LGSGG-------MPGMGS-NPLSGGVGQMPGAASGLPNPGAVPGAGS-AS Mflv_2790|M.gilvum_PYR-GCK LGSGG-------LPGMGS-NPLGSGVDQMPSAGSGLPSAGGVPGDGSGAG Mb2108|M.bovis_AF2122/97 LGQSF-------TTGMTTGTPAAAGAQALSAGALHAATEPLPPPAPPPTT Rv2082|M.tuberculosis_H37Rv LGQSF-------TTGMTTGTPAAAGAQALSAGALHAATEPLPPPAPPPTT TH_4387|M.thermoresistible__bu VGQMAG------QVPQQLSQPLQQLSQPLQQITSLFGAVGGKGPGALNAN MAB_1830|M.abscessus_ATCC_1997 AGSGGA------GSGLGSGSGGSGLPIGSTTAAGFSPSSTSTGVGGSGSG MUL_0572|M.ulcerans_Agy99 GGNGGAGGAGYAADGPAGPAIGNGGDGGHGGAGGFYGNGGAGGAGGNSAP MAV_2415|M.avium_104 VGGIAGARGALTDIAKSTADLPKNLEGVTKDLPEIKPPTGGAPVGLGPGG MMAR_1405|M.marinum_M GSGAG-------TEPSASATPPDAQLISQSSAAATAPQGLAAARAVAVVS MSMEG_0071|M.smegmatis_MC2_155 GTSIAPS----SPLSSGSSLGGSGAEQAADASAAALGQNPVGRAPVDPLQ MLBr_01556|M.leprae_Br4923 AEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPE Mvan_3258|M.vanbaalenii_PYR-1 PLSSAFNQGMATTAGMGGGIPSAPPPAPASPSPALSAGGGHAAPPVSAAP Mflv_2790|M.gilvum_PYR-GCK SPAVAFSQGMSTGGAIGGGMPAAPAPAPASPSPALSAG--AQAAPVPATA Mb2108|M.bovis_AF2122/97 PTVTTPTVATATTAGIPHIPDSAPTPSPAPIAPPTTDNASAMTPIAPMVA Rv2082|M.tuberculosis_H37Rv PTVTTPTVATATTAGIPHIPDSAPTPSPAPIAPPTTDNASAMTPIAPMVA TH_4387|M.thermoresistible__bu PFSSLSNHPLAGGSGPSGGAGMVRAASLPG-----AGGSSPQTPLIANML MAB_1830|M.abscessus_ATCC_1997 VGGPSGLSALRGGAGLPGGAAAGAGGGGVNPAGVGAAGVRGMGPMGMMGG MUL_0572|M.ulcerans_Agy99 GGGTGGNGGTGGDSGAMGSSGGRGGDGGVGTNGGAGGGGGNATSYGTANA MAV_2415|M.avium_104 KPIEAPVESAPRPPDGTPGAQRGSPPVATSPASPGPAGDSGAGPHGPSSS MMAR_1405|M.marinum_M AACGAEVAPVAGSALGPAAASAPLSAAPLSALASAPAAAGAVPAPSPGPP MSMEG_0071|M.smegmatis_MC2_155 QFTQSFSDSAGTPVHAASTGGGSVPPPPLTPPPTVPAGESMGPASAHSTP MLBr_01556|M.leprae_Br4923 DEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRK Mvan_3258|M.vanbaalenii_PYR-1 GGGVSPAGAQAGMVSPATPAAAAPTGAGIG-GGGAPMMLPPGSMGPPAG- Mflv_2790|M.gilvum_PYR-GCK GGGVPPAAAQSGLVAPAAP----PTGAGMGTGGGAPMMLPPGSMGPPAGP Mb2108|M.bovis_AF2122/97 NG--PPASPAPPAAAPAGPLP--AYGADLRPPVTTPPATPPTPTGPISGA Rv2082|M.tuberculosis_H37Rv NG--PPASPAPPAAAPAGPLP--AYGADLRPPVTTPPATPPTPTGPISGA TH_4387|M.thermoresistible__bu GGKVSPVSVDTGAAAGATVVG----------------------------- MAB_1830|M.abscessus_ATCC_1997 AGGHGRGGKDEDDDDHATP------------------------------- MUL_0572|M.ulcerans_Agy99 TGGAGGDGGTGSTGNGGSGGDGGNGGTGHGGGGGPGGTAINYGAGDAFGG MAV_2415|M.avium_104 PAPAAPPGGPVGPHDPAPAPAPAASPGGPGGSGGVHDPAPAPAPAPAASG MMAR_1405|M.marinum_M SPPVSPLSPAASGNAVAPPSVAGAQPAAGTGLRATTAAGPAPAPGSVATT MSMEG_0071|M.smegmatis_MC2_155 TSLNSAPAAPVQPPAAGGPMG---------------AASGMPVAPPPLGP MLBr_01556|M.leprae_Br4923 ANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGA . . Mvan_3258|M.vanbaalenii_PYR-1 APPPAPTVPAGTVGSTNAPAAPAPSAASAAAG---------------PTL Mflv_2790|M.gilvum_PYR-GCK VPPPAATVPAGALGAGSNAPSAAPPAAAAGAG---------------PTL Mb2108|M.bovis_AF2122/97 AVTPSSPAAGGSLMSPVVNKSTAPATTQAQPS---------------NPT Rv2082|M.tuberculosis_H37Rv AVTPSSPAAGGSLMSPVVNKSTAPATTQAQPS---------------NPT TH_4387|M.thermoresistible__bu ---------------------AAPVAAGMGGG---------------MGM MAB_1830|M.abscessus_ATCC_1997 ----------------QILINYDNTDEFMGDM---------------PAA MUL_0572|M.ulcerans_Agy99 AAGKGGTGVVGGNGGSGGAAYNYGTGNATGAG---------------GSS MAV_2415|M.avium_104 GPGDPASVPSGGPHEPASVPAEEPREPVSVPAGGVHDP------VAEPTG MMAR_1405|M.marinum_M HAAAPSSRPVSNWSPHDRDPFSPPAAGVAGDG----AT------GPIISP MSMEG_0071|M.smegmatis_MC2_155 PPTPPPAAPVAAPPPAAAPPPAQPNAAGGGAQ---------------VAP MLBr_01556|M.leprae_Br4923 KATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAK Mvan_3258|M.vanbaalenii_PYR-1 IPASVVAAGQTAAARERRESADAAAAKELVWKLQHAAYVALNPAAGWAVG Mflv_2790|M.gilvum_PYR-GCK IPASVVAAGQTAAARERRESADAAAAKELVWKLQHASYMAGNYLTGWAVG Mb2108|M.bovis_AF2122/97 PPLASATAAATTGAAAGDTSRRAAEQQRLRRILDTVARQE--PGLSWAAG Rv2082|M.tuberculosis_H37Rv PPLASATAAATTGAAAGDTSRRAAEQQRLRRILDTVARQE--PGLSWAAG TH_4387|M.thermoresistible__bu APGMMGARGTSGGTRPG-----IAAPEMLEHDLGEDEDDD------W--- MAB_1830|M.abscessus_ATCC_1997 SPGVIGDWSEQEKAEKAAREREVRRYKALGWDVKFE-------------- MUL_0572|M.ulcerans_Agy99 GSGGAASVPNSASTATATSGSGGAGGDGTDGGNGGSGGFAFTFGTGNIIA MAV_2415|M.avium_104 GPHEPASVPAAGSRLASVQAAAGDGLPSATPQLFDHTPSQVPVPAGGSSG MMAR_1405|M.marinum_M LTGGCDPLVVPAVLIPPTSSSAALGDQDLATVRSVVEAAGGASQVHWAAG MSMEG_0071|M.smegmatis_MC2_155 IPVSAARAERDLAQRAVRRSGVDPMETARRIAAALNAPGMTNVEDFKFFW MLBr_01556|M.leprae_Br4923 IRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLR Mvan_3258|M.vanbaalenii_PYR-1 VFRSPSGTETVITSNDGSSYIPAGVFVPRSVRVLATDPLVDDSFRQRWFG Mflv_2790|M.gilvum_PYR-GCK VFRSPSGTETVITSNDGASYIPAGVFVPRSVRVLATDLVIHDSFRQLWFG Mb2108|M.bovis_AF2122/97 LRDN--GQTTLLVTDLASGWIPPHIRLPAHITLLEPAP------------ Rv2082|M.tuberculosis_H37Rv LRDN--GQTTLLVTDLASGWIPPHIRLPAHITLLEPAP------------ TH_4387|M.thermoresistible__bu -------------------------------------------------- MAB_1830|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 GVGGGGGTGSTGVGGIGGSGGGADINNGAFTVVPQGGAGGHGGDGATDGG MAV_2415|M.avium_104 EAASVGAHSPSSASSAAPHFESPGGRPSEVPAPNGGAHGPGESGPAGGHP MMAR_1405|M.marinum_M MVVTSGRRQVVLTSDRGRSWVPAEAFLPADVITP---------------- MSMEG_0071|M.smegmatis_MC2_155 VTGLTADGKIVVANNYGIAYIPQQVHLPEQVHMASADESIS--------- MLBr_01556|M.leprae_Br4923 ANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRR Mvan_3258|M.vanbaalenii_PYR-1 WGDPARVLVEYAQLRAQWGWKLVAAATTAGV-------SVLRDAGVEHPP Mflv_2790|M.gilvum_PYR-GCK WSDPARVLVEYAQQRAEWGWRLVAAASTLPT-------PALRDAGVEHPP Mb2108|M.bovis_AF2122/97 --------------------RRRHATVTDLL-------GTTTVAAAHHPH Rv2082|M.tuberculosis_H37Rv --------------------RRRHATVTDLL-------GTTTVAAAHHPH TH_4387|M.thermoresistible__bu -------------------------------------------------- MAB_1830|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 AGGAGGFTEIDSSASVIAATGGAGGDGGSGG-------TGRGGTGGGGTG MAV_2415|M.avium_104 PGEPPHGGKPSGDGGPPDEDSHRDGTPGNGD-------DGAAGEIDDGPA MMAR_1405|M.marinum_M -------------------WSHEQSSRWGGL-------LDPARVIVEYAA MSMEG_0071|M.smegmatis_MC2_155 --------------------PAERARWVNEP-------IVAVQRWAEHHG MLBr_01556|M.leprae_Br4923 MVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRS Mvan_3258|M.vanbaalenii_PYR-1 SCSGDTNPLLQQGVDVPAPVLDDMHIHRLAVLWPEVYPRLLRIMDADPLC Mflv_2790|M.gilvum_PYR-GCK ACTRETNPLLQPGVQVPAPVLDDMHVHRLAVLWPEVYPRLLRVMDADPIC Mb2108|M.bovis_AF2122/97 GYLSQPDP--------DTPALTGDRTARIAPTIDELGPTLV-----ETVR Rv2082|M.tuberculosis_H37Rv GYLSQPDP--------DTPALTGDRTARIAPTIDELGPTLV-----ETVR TH_4387|M.thermoresistible__bu -------------------------------------------------- MAB_1830|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 GGGTGGGGGVGINNGSGEAIGGAPGAGGTGAVGGDGGQGGAAYSYGTGDA MAV_2415|M.avium_104 GVDGQSTPAKVAGVDYPLPPSDALRVLEHPGAELQRLADGGVPSSILEGY MMAR_1405|M.marinum_M AAGG--------------RLTALASTFSGAPAVAAGIPWTLVDGTDRAHP MSMEG_0071|M.smegmatis_MC2_155 KNLRAVIATEDQLKNSDAGVHHEVLRPEDIPEGGKMAGRDRLQVIAPDVS MLBr_01556|M.leprae_Br4923 ARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALM Mvan_3258|M.vanbaalenii_PYR-1 QDRIVSAVTAAMINAATTQAQVIDGGIDEALRLVWAVRGSDREPTVQQWA Mflv_2790|M.gilvum_PYR-GCK QDRIVSGVSAALMVAATTQAQAVE--IPDALRHIWVARGGDREPSTQQWA Mb2108|M.bovis_AF2122/97 RHDTLPRIAQAVVVAATRNYGVPD-------------------------- Rv2082|M.tuberculosis_H37Rv RHDTLPPIAQAVVVAATRNYGVPD-------------------------- TH_4387|M.thermoresistible__bu -------------------------------------------------- MAB_1830|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 TGSAGAAGTAGTTGVGGTGGAGGAAYTLNGASTATATGGIGGNGGDGGTA MAV_2415|M.avium_104 EPLAGRSVDDFNREFTIETSNGERGWDWEAQAPENGFAGNPIESNHIPAG MMAR_1405|M.marinum_M ELLSGPVVTRFELQVSPERRRAVK-------------------------- MSMEG_0071|M.smegmatis_MC2_155 AQLARVSDTDLVKILPPAPADANP-------------------------- MLBr_01556|M.leprae_Br4923 GIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELA Mvan_3258|M.vanbaalenii_PYR-1 DYDKAAKALNVMTAMRRPAFATNTGAVADPSDTTEFLADYRAHWLVARTA Mflv_2790|M.gilvum_PYR-GCK KYNEEAQTFNGTTAMSRPAFLT--GGAGHPRDSSEELANYRGHWLVARTI Mb2108|M.bovis_AF2122/97 --NETDLLHHKTTEIHQAVLTT---------YPNHDIATVVDWMLLAAIN Rv2082|M.tuberculosis_H37Rv --NETDLLHHKTTEIHQAVLTT---------YPNHDIATVVDWMLLAAIN TH_4387|M.thermoresistible__bu -------------------------------------------------- MAB_1830|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 NGSNGGNGGAGGYASTTGTGTASVGNGGRGGDGTATVATGGTGGVGGNAH MAV_2415|M.avium_104 LHFDRIGPNGGGFLSPEGVPLAERATPPGLAAQYHVFEGTGREIPAGKDW MMAR_1405|M.marinum_M --HITDPVKQRVQVLWLALSADETAGSLGTRGRMLSLFRDHLGRIDRPRW MSMEG_0071|M.smegmatis_MC2_155 --PEDRRKLLWDNVWKPLASRSTKRGERHLAAFVAYAAHAQEHALYAAHT MLBr_01556|M.leprae_Br4923 SREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSK Mvan_3258|M.vanbaalenii_PYR-1 EHIGGWSRRPLPLPDMCYAAAATGDPDLRDMIVKALVSVEEDLQYEAPR- Mflv_2790|M.gilvum_PYR-GCK EHIGGWANRPLPLPDMCYAAAATGDPDLHDKIVKALVSVEDDLAVGS--- Mb2108|M.bovis_AF2122/97 ALIAGDQSGANYHLAWAIAAISTRRSR----------------------- Rv2082|M.tuberculosis_H37Rv ALIAGDQSGANYHLAWAIAAISTRRSR----------------------- TH_4387|M.thermoresistible__bu -------------------------------------------------- MAB_1830|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 APAGSPVPGVGGKGGNPGPGGKPGPNGADGIVV----------------- MAV_2415|M.avium_104 VVQHGPAKEAFGQPGGGDQWIVLDRATNRPVPVDELIRRRLLREITPPND MMAR_1405|M.marinum_M VASLPWEQLEDEHHRLCVQERAARL------------------------- MSMEG_0071|M.smegmatis_MC2_155 AALPDDQRQAIREFIYWQHVGQLTADALSPA------------------- MLBr_01556|M.leprae_Br4923 VGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVRE Mvan_3258|M.vanbaalenii_PYR-1 ------------------------------ Mflv_2790|M.gilvum_PYR-GCK ------------------------------ Mb2108|M.bovis_AF2122/97 ------------------------------ Rv2082|M.tuberculosis_H37Rv ------------------------------ TH_4387|M.thermoresistible__bu ------------------------------ MAB_1830|M.abscessus_ATCC_1997 ------------------------------ MUL_0572|M.ulcerans_Agy99 ------------------------------ MAV_2415|M.avium_104 KLAIGYRGS--------------------- MMAR_1405|M.marinum_M ------------------------------ MSMEG_0071|M.smegmatis_MC2_155 ------------------------------ MLBr_01556|M.leprae_Br4923 GFECGMTLGYSDIKEGDVIESYELVEKQRA