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VAFDAAMSTHEDLLATIRYVRDRTGDPNAWQTGLTPTEVTAVVTSTTRSEQLDAILRKIRQRHSNLYYPA PPDREQGDAARAIADAEAALAHPNSATAQLDLQVVSAILNAHLKTVEGGESLHELQQEIEAAVRIRSDLD TPAGARDFQRFLIGKLKDIREVVATASLDAASKSALMAAWTSLYDASKGDRGDADDRGPASVGSGGAPAR GAGQQPELPTRAEPDCLLDSLLLEDPGLLADDLQVPGGTSAAIPSASSTPSLPNLGGATMPGGGATPALV PGVSAPGGLPLSGLLRGVGDEPELTDFDERGQEVRDPADYEHSNEPDERRADDREGADEDAGLGKSESPP QAPTTVTLPNGETVTAASPQLAAAIKAAASGTPIADAFQQQGIAIPLPGTAVANPVDPARISAGDVGVFT DRHALALGPSKALLDGQIQHISAVRGRNFLGWIHPAATATAPARTEAPTPTRPAAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0027 | - | - | 100% (477) | hypothetical protein Mb0027 |
| M. bovis AF2122 / 97 | Mb0760 | - | 3e-09 | 37.84% (111) | hypothetical protein Mb0760 |
| M. bovis AF2122 / 97 | Mb0026 | - | 1e-08 | 31.25% (112) | hypothetical protein Mb0026 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0026 | - | 0.0 | 99.76% (420) | hypothetical protein Rv0026 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0045 | - | 1e-110 | 54.99% (411) | hypothetical protein MMAR_0045 |
| M. avium 104 | MAV_0044 | - | 1e-146 | 57.66% (496) | hypothetical protein MAV_0044 |
| M. smegmatis MC2 155 | MSMEG_4365 | - | 6e-05 | 23.90% (251) | hypothetical protein MSMEG_4365 |
| M. thermoresistible (build 8) | TH_3514 | - | 4e-07 | 24.64% (414) | PUTATIVE putative hypothetical protein Mflv_4945 |
| M. ulcerans Agy99 | MUL_0044 | - | 1e-107 | 54.13% (412) | hypothetical protein MUL_0044 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0027|M.bovis_AF2122/97 ------------------MAFDAAMSTHEDLLATIRYVRDRTGDPNAWQT
Rv0026|M.tuberculosis_H37Rv ------------------MAFDAAMSTHEDLLATIRYVRDRTGDPNAWQT
MAV_0044|M.avium_104 ------------------------MSAYDDLLAAVKDVRDRTGDPNAWQT
MMAR_0045|M.marinum_M ------------------------MGGSE--------QRAQSG-------
MUL_0044|M.ulcerans_Agy99 ------------------------MGGSE--------QRAQSG-------
TH_3514|M.thermoresistible__bu VTGGLDVAARLADGLPAVRAAQEYLSACESLGYRQPDLSGRPGQVFDWYR
MSMEG_4365|M.smegmatis_MC2_155 --MGRIGALAVALGIGAALTTGTGVAWADDSGASGGSTSSSSSASDSSSS
:. : ..
Mb0027|M.bovis_AF2122/97 GLTPTEVTAVVTSTTRSEQLDAILRKIRQRHSNLYYPAP-----------
Rv0026|M.tuberculosis_H37Rv GLTPTEVTAVVTSTTRSEQLDAILRKIRQRHSNLYYPAP-----------
MAV_0044|M.avium_104 GLAPAEVSAVITPSTRPEQLQAILAKIRRQHAEVFGAAPTGVARPPADAG
MMAR_0045|M.marinum_M --------------------------------------------------
MUL_0044|M.ulcerans_Agy99 --------------------------------------------------
TH_3514|M.thermoresistible__bu SEDGLDLGALADDSAALDRAAARAAEVLELQDRQSAALGAGWRGVGGTAA
MSMEG_4365|M.smegmatis_MC2_155 SAGGSSGSASGGADAAKPRKPGVTKPRIQPTGKIAESLKKT---------
Mb0027|M.bovis_AF2122/97 --PDREQGDAARAIADAEAALAHPNSATAQLDLQVVSAILNAHLKTVEGG
Rv0026|M.tuberculosis_H37Rv --PDREQGDAARAIADAEAALAHQNSATAQLDLQVVSAILNAHLKTVEGG
MAV_0044|M.avium_104 PAPDRESGAAADAIASAEAALAQQNSVSSQLDMQVVTAILNAHLKAVDGR
MMAR_0045|M.marinum_M ----AARGAAADAIAGAEVALAHQNSMSSQLDLQVIAAILNAHLTAVDGS
MUL_0044|M.ulcerans_Agy99 ----AAGGAAADAIAGAKVALAHQNSMSSQLDLQVIAAILNAHLTAVDGS
TH_3514|M.thermoresistible__bu AELLRRHGAASAAATAALRTAADALTTLRTELWQLVDRKVTATQGIDGGG
MSMEG_4365|M.smegmatis_MC2_155 --AKAVEGAVADAHKRAQQSAAQQAEKRAERRAKLRAQIRPGKDTDKQAP
* .: * * : *. :: . .
Mb0027|M.bovis_AF2122/97 ESLHELQQEIEAAVRIRSDLDTPAG---------------ARDFQRFLIG
Rv0026|M.tuberculosis_H37Rv ESLHELQQEIEAAVRIRSDLDTPAG---------------ARDFQRFLIG
MAV_0044|M.avium_104 EALTKLQQETEAAVRTRSDLDTPAG---------------ARDFQRFLIG
MMAR_0045|M.marinum_M EALDELQQETEAAVRTRSDLDTPAG---------------ARDFQRFLIG
MUL_0044|M.ulcerans_Agy99 EALDELQQETEAAVRTRSDLDTLAG---------------ARDFQRFLIG
TH_3514|M.thermoresistible__bu RTDWQAAAHTVLTGAGDRSVASELV---------------DAEVKPFVDE
MSMEG_4365|M.smegmatis_MC2_155 EKQAGNEAKNAAQPATKTQRQLPAAPAVKVPDVITSVRARSDEVAREITT
. . . :. :
Mb0027|M.bovis_AF2122/97 KLKDIREVVATAS-------LDAASKSALMAAWTSLYDASKGDRGDADDR
Rv0026|M.tuberculosis_H37Rv KLKDIREVVATAS-------LDAASKSALMAAWTSLYDASKGDRGDADDR
MAV_0044|M.avium_104 KLRDIRAVVLNAS-------LDDTSKSALMAAWTSLYDAAKNDR--PGDH
MMAR_0045|M.marinum_M KLRDIREVVATAS-------LDDTSKATLMAAWTSLYNASKQEASSPGDV
MUL_0044|M.ulcerans_Agy99 KLRDIREVVATAS-------LDDTSKATLMAAWTSLYNASKQEASSPGDA
TH_3514|M.thermoresistible__bu AIGCEWLTVMNQT-------LTSIEEKFDAAIAELTGSAAVPDFGAGEGE
MSMEG_4365|M.smegmatis_MC2_155 GVTGIRTAIENAAPRIALPDLRPTTNLARPVTPVALKAAQPVQVSPPRPT
: .: . : * : . * :
Mb0027|M.bovis_AF2122/97 GP-----ASVGSGGAPARGAGQQPELPTRAEPDCLLDSLLLEDPGLLAD-
Rv0026|M.tuberculosis_H37Rv GP-----ASVGSGGAPARGAGQQPELPTRAEPDCLLDSLLLEDPGLLAD-
MAV_0044|M.avium_104 AS-----SAGAAADAAAAGTSDQPDEDLDDEWDPLLDSLLADDDGSPIDP
MMAR_0045|M.marinum_M PT-----ATEPAAGTGADAVRAAG----LTSGDPLLDSLLFDDPGLVAE-
MUL_0044|M.ulcerans_Agy99 QT-----ATEPAAGTGPDADRAAG----LISGDPLLDSLLFDDPGLVDE-
TH_3514|M.thermoresistible__bu AP-----PWAANWGPPWAANWGQPGAASWGSP-PVADGAASAIGADPAP-
MSMEG_4365|M.smegmatis_MC2_155 ITGLVRGLLTAAAGFSPRAATAPVAPAPSPAAWALLAFARREFERAFTPG
. . . :
Mb0027|M.bovis_AF2122/97 --DLQVPGG-TSAAIPSASSTPSLP----NLGGATMPGGGATPALVPGVS
Rv0026|M.tuberculosis_H37Rv --DLQVPGG-TSAAIPSASSTPSLP----NLGGATMPGGGATPALVPGVS
MAV_0044|M.avium_104 AAALDPLGGNTIPPAPPPAMAPALP----SFGGGSLPGLGATPASMSGWE
MMAR_0045|M.marinum_M ---APLPQGAAPSGAATAPALPSMP----SLGDGSGAATPSGAGSVP--N
MUL_0044|M.ulcerans_Agy99 ---ATLPQGAAPSGAATAPSLPSMP----SLGDGSGAATPSGAGSVP--N
TH_3514|M.thermoresistible__bu --AEAAAPGVPPPAVPPTGPGGGLP----DPGAGLSTVGRQLVDLLGGLL
MSMEG_4365|M.smegmatis_MC2_155 AATALAAPAITTSAVTSAAVVNPLPGRLDSVPVGWVTGVSNPSGNWPQTN
. . . ... :* . . .
Mb0027|M.bovis_AF2122/97 APGGLPLSGLLRGVGDEP-ELTDFDERGQEVRD-----------------
Rv0026|M.tuberculosis_H37Rv APGGLPLSGLLRGVGDEP-ELTDFDERGQEVRD-----------------
MAV_0044|M.avium_104 TPGGLPLSGLQAGDASDP-ALQDLADEDLPEDQ-----------------
MMAR_0045|M.marinum_M LPAGPALSAIPRAIASRLDELDDPSLDSLALDP-----------------
MUL_0044|M.ulcerans_Agy99 LPAGPALSAIPRAIASRLDELDDPSLDSLALDPDASG-------------
TH_3514|M.thermoresistible__bu GPVGEALGNGVGAAGVDPMGGEDAGGEDAGTEERDGA-------------
MSMEG_4365|M.smegmatis_MC2_155 NTAGFDIWGTDLGIMWDGGEWNGQRFVHTAFGDTFSGPNMSGWWRSNVLL
. * : . .
Mb0027|M.bovis_AF2122/97 PADYEHSNE---------------------------------PDERRADD
Rv0026|M.tuberculosis_H37Rv PADYEHSNE---------------------------------PDERRADD
MAV_0044|M.avium_104 GQQHDSPAD---------------------------------GSAEQADD
MMAR_0045|M.marinum_M DDSDDEPAD---------------------------------LDEDTDGG
MUL_0044|M.ulcerans_Agy99 DDSDDEPAD---------------------------------LDEDTDGG
TH_3514|M.thermoresistible__bu SDADTDAED---------------------------------DDRGDDTP
MSMEG_4365|M.smegmatis_MC2_155 ISTDNVLSDGLGLVQTGTAYQFIPASGRNLFGLFGGSEVTVIPTAGVQID
:
Mb0027|M.bovis_AF2122/97 REGADEDAGLGKSESPPQAPT-----TVTLPNGETVTAASPQLAAA--IK
Rv0026|M.tuberculosis_H37Rv REGADEDAGLGKSESPPQAPT-----TVTLPNGETVTAASPQLAAA--IK
MAV_0044|M.avium_104 -ENASADE-------PPAGPT-----SVTLPDGETVTAASPQLAAA--IK
MMAR_0045|M.marinum_M GEDTEQPASSGEPQPLPTGPT-----TVTLPNGDTITAASPELAAA--IN
MUL_0044|M.ulcerans_Agy99 GEDTEQPASSGEPQPLPTGPT-----TVTLPNGDTITAASPELAAA--IN
TH_3514|M.thermoresistible__bu EDDTPDDGDPDAGGSPGEDPQ-----EAPDPEHDPDPAPGEPETHX--XX
MSMEG_4365|M.smegmatis_MC2_155 GTQYVNYMSVRSWDTPGRWTTNFSAISVYDPSTDTWVLAPSTIRSAGWFR
. . *. :. .
Mb0027|M.bovis_AF2122/97 AAASGTPIADAFQQQGIAIPLPGTAVA-------------NPVDPARISA
Rv0026|M.tuberculosis_H37Rv AAASGTPIADAFQQQGIAIPLPGTAVA-------------NPVDPARISA
MAV_0044|M.avium_104 AAVAGTPIAEAFQQQGMTLPAPGTAVA-------------NPVDVVRVSP
MMAR_0045|M.marinum_M ATAGGAAIADAFQQQGIAIPPPGTPVS-------------DPIDPARLAA
MUL_0044|M.ulcerans_Agy99 AAAGGAAIADAFQQQGIAIPPPGTPVS-------------DPIDPARLAA
TH_3514|M.thermoresistible__bu AGPGDVAIDFSGSTEALGEALDRLDVGG-------VLVLAGSVSPAPALP
MSMEG_4365|M.smegmatis_MC2_155 SSTLYVPGSQNFQQAAYVLQPEDQVGEDGIRYLYAFGTPSGRAGSAYLSR
: .. . . . . .
Mb0027|M.bovis_AF2122/97 GDVGVFTDRHALALGPSKALLDGQIQHISAVRG-----------------
Rv0026|M.tuberculosis_H37Rv GDVGVFTA-TPLPLALAKLFWTARFNTSQPCEG-----------------
MAV_0044|M.avium_104 GDIGMFTDRHALALGPGKALLDGQIQHIATVSG-----------------
MMAR_0045|M.marinum_M GDIGMFTDRHALALGDGNAFLDGQMQQVSSIGG-----------------
MUL_0044|M.ulcerans_Agy99 GDIGMFRDWHALALGDGNAFLDGQIQQVSSIGG-----------------
TH_3514|M.thermoresistible__bu VDPELIVRRWLTLTGVHNYEPQHLRDAVAFLRHS----------------
MSMEG_4365|M.smegmatis_MC2_155 VPEDAVTDLSKYEYWDGNRWVTGNAAVAAPVIGDSTRSTGLFGFIVDWAN
. :
Mb0027|M.bovis_AF2122/97 -RNFLG--------------------------WIHP---AATATAPARTE
Rv0026|M.tuberculosis_H37Rv -QTF----------------------------------------------
MAV_0044|M.avium_104 -PSFLG--------------------------WEHPPAAAASVTAPAKPD
MMAR_0045|M.marinum_M -PNFLG--------------------------WQHPP-TSTTVTAPAQTG
MUL_0044|M.ulcerans_Agy99 -PNFLG--------------------------WQHPP-TSTTVTEPAQTG
TH_3514|M.thermoresistible__bu -RDRFD--------------------------WPALVDDPVGLDDIAAAL
MSMEG_4365|M.smegmatis_MC2_155 DPNVLGGYLGGLVGAKTGGNVSELSVQYNEYLGKYVVLYGDGNNNIQMRI
Mb0027|M.bovis_AF2122/97 APTPTRPAAAR---------------------------------------
Rv0026|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0044|M.avium_104 PPTPTRPASSSTT-------------------------------------
MMAR_0045|M.marinum_M APTPTRPATTPVAPRY----------------------------------
MUL_0044|M.ulcerans_Agy99 APTPTRPATTPVAPRY----------------------------------
TH_3514|M.thermoresistible__bu MPAPTGRLRKAVSPGLPPRTAARNSPGSRPPDS-----------------
MSMEG_4365|M.smegmatis_MC2_155 ADRPEGPWSDPIELASSADYPGLYAPMIHPWSGTGMLEDDNGDPDVNNLY
Mb0027|M.bovis_AF2122/97 --------------------------
Rv0026|M.tuberculosis_H37Rv --------------------------
MAV_0044|M.avium_104 --------------------------
MMAR_0045|M.marinum_M --------------------------
MUL_0044|M.ulcerans_Agy99 --------------------------
TH_3514|M.thermoresistible__bu --------------------------
MSMEG_4365|M.smegmatis_MC2_155 WNMSLWGDYNVVLMQTDLSGLKTVAV