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MTMEFSLQAVSVLAQSSGDEGGGTALSEIVALSAAGAVVTAVLLWIGWQHRNHKITWLAGLADWSARRFK RPPWVALPIAMFIASIICALFGFIWDVSLHIGNGRDDGALANPAHYFILIGLFGIFVAGCTAMVLPYDRP GPAAVRITDDWYAPVGGIVMAGCGLYALLGFPLDDMWHRIFGQDVTLWGPTHLMMIGGAGFSTLAALYLE YEGRRVRTDETPPDGIGLKFVQYLAFAGVLIGASVYQIEFDFGVPQFRQVFQPMLIAAAAALALVAARIF MGRGAALIAALIAIGLRGLVAVAVGPVLDAPLNWFPLYLGAALVVEILALTPLLRRPVLFGLVSGLGIGT VGLWLESLWIGAVYPYPWPTSIWPEALAMSVPVAVLTGGCGAMVGMVLTGRRLPGRAVGIGLVALTVLAI GGAAANGLRYDTPQNATASVTLTEAPAVDGQRFVTADVRFNPPDVIGDNPNWVSVLGWQGGLPNERGQFV DHLEKVGVGHYRSTEPMPVSGTWKTLLRVHDGRTLTAVPIYLAGDPGIGAEEVPAEAQFTRPFVSEITIL QRERSPDIPASLWLIGCLVVLLCTLAMIAGISWGAGRINNSEPSGSEAEFAPSAQS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5724 | - | - | 100% (616) | hypothetical protein Mvan_5724 |
| M. vanbaalenii PYR-1 | Mvan_5838 | - | 6e-05 | 27.62% (210) | hypothetical protein Mvan_5838 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1094 | - | 0.0 | 85.74% (617) | hypothetical protein Mflv_1094 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1632c | - | 0.0 | 61.86% (603) | hypothetical protein MAB_1632c |
| M. marinum M | MMAR_5199 | - | 6e-05 | 27.17% (184) | hypothetical protein MMAR_5199 |
| M. avium 104 | MAV_3198 | - | 0.0 | 64.25% (579) | hypothetical protein MAV_3198 |
| M. smegmatis MC2 155 | MSMEG_6500 | - | 0.0 | 65.38% (595) | hypothetical protein MSMEG_6500 |
| M. thermoresistible (build 8) | TH_1792 | - | 0.0 | 82.10% (609) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4272 | - | 4e-05 | 27.17% (184) | hypothetical protein MUL_4272 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5724|M.vanbaalenii_PYR-1 MTMEFSLQAVSVLAQSSGDEGGGTALSEIVALSAAGAVVTAVLLWIGWQH
Mflv_1094|M.gilvum_PYR-GCK --MELSLQAE-VLAQ--GSEGGGAAISEIITLSAAGAVIAVILLWIGWMH
TH_1792|M.thermoresistible__bu -----------VLAQ--ADEGGGAALSEIIGLSVAAAVVTLVLLWIGYLH
MAB_1632c|M.abscessus_ATCC_199 -----MTTHSVRIIAAAN-EGGGAALDQVIGMSVAATIVSVGLLWIGYLH
MSMEG_6500|M.smegmatis_MC2_155 ----MVGSSQVSLFAAEGTEGGGAALDQVIGLSAVATVITAALLWIGYLH
MAV_3198|M.avium_104 -----MRSDELTIVAEAP--ARGAGLNQVIGLSLAAVVITLLMLWVGHAH
MMAR_5199|M.marinum_M --------------------------------------------------
MUL_4272|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5724|M.vanbaalenii_PYR-1 RNHKITWLAGLADWSARRFKRPPWVALPIAMFIASIICALFGFIWDVSLH
Mflv_1094|M.gilvum_PYR-GCK RTRKITWLARLGDWSGRRFKRPPWVALPIGLFISSIICALFGFIWDVSLH
TH_1792|M.thermoresistible__bu RSHKITWLTGLGDWAGRRFKRPSWVALPIALFIASIICALFGFIWDVSLH
MAB_1632c|M.abscessus_ATCC_199 RQRRITWLQSLADKVGNKFNRPPWVALQICLFVTTIVAALFGFIWDVSLH
MSMEG_6500|M.smegmatis_MC2_155 RQRRITWLNNFAERLGRKFHRPPWVALQIFLFTSTIICALFGFIWDVSLH
MAV_3198|M.avium_104 RTHRIQWLTRIADKMGEKFHRPNWVALPVLIFTTSIICALFGFIWDVSWH
MMAR_5199|M.marinum_M -----------------------MSTLPPPGYPVEPNSGAPGYEAAGYPP
MUL_4272|M.ulcerans_Agy99 -----------------------MSTLPPPGYPVEPNSGAPGYEAAGYPP
:* : .. *:
Mvan_5724|M.vanbaalenii_PYR-1 IGNGRDDGALANPAHYFILIGLFGIFVAGCTAMVLPYD----RPGPAAVR
Mflv_1094|M.gilvum_PYR-GCK IGNGRDDGALANPAHYFILIGLFGIFVAGCTAMVLPLDE---KPGVAAVR
TH_1792|M.thermoresistible__bu IGNGRDDGALANPAHYFILIGLFGIFVAGCTAMVLPLGGADAKPGPSAVR
MAB_1632c|M.abscessus_ATCC_199 IGKGRDAGPLANPAHYFILFGLFLLFIAGTLAMVLPYD----KPGSAAVR
MSMEG_6500|M.smegmatis_MC2_155 IGQGRDEGPLANPAHYFILVGLFLLFIAGVLAMVLPYE----KPGPAAIR
MAV_3198|M.avium_104 IGNGRDPGPLANPAHYFIIIGLFGVFLGGMVSVVLPFD----KPGPAAVR
MMAR_5199|M.marinum_M SGYADPPPAYGPPPAYGPPPGYG-------------------APPPGYGP
MUL_4272|M.ulcerans_Agy99 SGYADPPPAYGPPPAYGPPPGYG-------------------APPPGYGP
* . . . *. * * * .
Mvan_5724|M.vanbaalenii_PYR-1 ITDDWYAPVGGIVMAGCGLYALLGFPLDDMWHRIFGQDVTLWGPTHLMMI
Mflv_1094|M.gilvum_PYR-GCK ITDDWYAPVGGIVMAGCGVYALLGFPLDDIWHRIFGQDVTLWGPTHLMMI
TH_1792|M.thermoresistible__bu ITDHWYAPVGGIVMAGCGLYALMGFPLDDMWHRIFGQDVTLWGPTHLMMI
MAB_1632c|M.abscessus_ATCC_199 ITRTWYAPVGGLLMAMCGLYALIGFPLDDIWHRIFGQDVTLWGPTHLMLI
MSMEG_6500|M.smegmatis_MC2_155 ITRTWYAPVGGVLMALCGLYALIGFPLDDIWHRIFGQDVTLWGPTHLMLI
MAV_3198|M.avium_104 ITRNWYAPVGGVLMAGCGLYAMIGFPLDDIWHRIFGQDVTLWGPTHLMMI
MMAR_5199|M.marinum_M PPPGYGPPP-GYGPPPPGYGPPPGYGPPPPG-------------------
MUL_4272|M.ulcerans_Agy99 PP-GYAPPPPGYGPPP-GYGPPPGYGPPPPG-------------------
. : .* * . * . *:
Mvan_5724|M.vanbaalenii_PYR-1 GGAGFSTLAALYLEYEGRRVRT--DETPP-----DGIGLKFVQYLAFAGV
Mflv_1094|M.gilvum_PYR-GCK GGAGFSTLAALYLEYEGRKARTGAEDVPR-----DGLGLKFVQYLAFAGV
TH_1792|M.thermoresistible__bu GGAGFSTLAAAYLELEGKRVRG--PDTPP-----DGPGLKFIQYLAFAGV
MAB_1632c|M.abscessus_ATCC_199 GGAGLSLVSVLILEYEGRRAIG--FSAD-----DDTRFVKFLRYLSFGGL
MSMEG_6500|M.smegmatis_MC2_155 GGAGLSLIAVLLLEHEGRVAMA--GNSSPGDIKDDTRFNTFLRYLSFGGL
MAV_3198|M.avium_104 GGAGFSLFAVLMLEREGEAAEG--EDVY------HSVFIRFLRYLSFGGM
MMAR_5199|M.marinum_M --------------------------------------------------
MUL_4272|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5724|M.vanbaalenii_PYR-1 LIGASVYQIEFDFGVPQFRQVFQPMLIAAAAALALVAARIFMGRGAALIA
Mflv_1094|M.gilvum_PYR-GCK LIGASVYQIEFDFGVPQFRQVFQPMLIAAAAGLALVAARIFMGRGAALIA
TH_1792|M.thermoresistible__bu LIGASVYQIEFDFGVPQFRQVFQPMLIAAAAALALVGARIFLGRGAAIIA
MAB_1632c|M.abscessus_ATCC_199 FIGLSVFQIEYDFGVEQFRLVQQPMMIAAAAAFAAVCARIVMGRGAAIIG
MSMEG_6500|M.smegmatis_MC2_155 FIGLSVFQIEYDFGVEQFRLVLQPMMIAGAAALAAVAARLVLGPGAAVIA
MAV_3198|M.avium_104 FIGLSVFQIEYDFGVEQFRLVLQPMMIAGAAALAAVAARITMGRGAALIA
MMAR_5199|M.marinum_M -YGPPLVPGAVKPGIIPLRPLTLSDIFNGAVGYIRANPKATLGLTAIVVV
MUL_4272|M.ulcerans_Agy99 -YGPPLVPGAVKPGIIPLRPLTLSDIFNGAVGYIRANPKATLGLTAIVVV
* .: . *: :* : . :: .*.. . .: :* * ::
Mvan_5724|M.vanbaalenii_PYR-1 ALIAIGLRGLVAVAVGPVLDAPLNWFPLYLGAALVVEILALTPLLRRPVL
Mflv_1094|M.gilvum_PYR-GCK ALIAIGLRGIVALAVGPVLDAPINWFPLYLGAAVVVELVALTPLIRKPIL
TH_1792|M.thermoresistible__bu ALVAIGLRGIVALLVGPILGEPINWFPLYLGAAVVVELLALTPLFRRRVL
MAB_1632c|M.abscessus_ATCC_199 ALLAIVLRAAVALLAGPILGGPTSWFALYLGPALVVELIALTPLIKRPIL
MSMEG_6500|M.smegmatis_MC2_155 AVLAIVLRGAVSLAVGPVLGAPHSWWALYLGPALVVELVALTPLVKRPLV
MAV_3198|M.avium_104 AVFAIALRGAVAVLVGPVLGAPLNWFPLYLGPALAVELVALTPIFKRPIV
MMAR_5199|M.marinum_M VMQVITLLATIGPLEAASR------------------FDTHPSELSWGVV
MUL_4272|M.ulcerans_Agy99 VMQVITLLAAIGPLEAASR------------------FDTHPSELSWGVV
.: .* * . :. .. : : .. . ::
Mvan_5724|M.vanbaalenii_PYR-1 FGLVSGLGIGTVGLWLESLWIGAVYPYPWPTSIWPEALAMSVPVAVLTGG
Mflv_1094|M.gilvum_PYR-GCK FGLVAGLGIGTVGLYLESLWIGAVYAFPWPTSIWPEGLAMAVPVAILTGG
TH_1792|M.thermoresistible__bu FGLVSGLGIATVGLWLESLWIGTVYHLPWPAGIWPEALAMSIPVAVLTGA
MAB_1632c|M.abscessus_ATCC_199 FGALAGLGVGTAGLWLESLWIGAVYRYPWPVSMWPEALAMAVPAAIAMGI
MSMEG_6500|M.smegmatis_MC2_155 FGAVSGLAVATVGLWLESLWIGAVYTYPWPTSMWGEALAMSIPVAVGMGL
MAV_3198|M.avium_104 FGAVSGLGVGTLGLWLESLWISAVYHYPWPVSMWAEALAMAVPVAVLMGM
MMAR_5199|M.marinum_M GAWTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSPITISEAWARVRGR
MUL_4272|M.ulcerans_Agy99 GAWTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSPITISEAWARVRGR
. .. . . :* .: :. : .:: . :::: . * *
Mvan_5724|M.vanbaalenii_PYR-1 CGAMVGMVLTGRRLPGRAVGIGLVALTVLAIGGAAANGLRYDTPQNATAS
Mflv_1094|M.gilvum_PYR-GCK CGALVGMVLTGQRLPSRGISIGLVVLTVLAIGGAAANGLRYDVPQNASAS
TH_1792|M.thermoresistible__bu CGAMLGMVLTEERLPRRAVGVGLVALTVLAIGGATANGLRYDVPETATAT
MAB_1632c|M.abscessus_ATCC_199 CGALLGMVLIGQKLPARPVSITAVVLTVLILGAAVANGLRTEVPERATAT
MSMEG_6500|M.smegmatis_MC2_155 CGALLALVLTSRRLPRPAVGISIVVATVLAIGGAVANGLRIEVPENATAT
MAV_3198|M.avium_104 CGAMFGMVLTGQRLPGRAIGISVVVATVLVIGGAVANGLHIVVPRQNNAT
MMAR_5199|M.marinum_M ILALIGLALLEG---AGLVALAGLVVVILVGVAAAANGATAALLG-FPLV
MUL_4272|M.ulcerans_Agy99 ILALIGLALLEG---AGLVALAGLVVVILVGVAAAANGATAALLG-FPLV
*:..:.* :.: :. .:* .*.***
Mvan_5724|M.vanbaalenii_PYR-1 VTLTEAPAVDGQRFVTADVRFNPPDVIGDNPNWVSVLGWQGGLPNERGQF
Mflv_1094|M.gilvum_PYR-GCK FTLTEAPPVNGERFVTADVRFTPPDVISEDPNWVSVLGWQGGLPNDRGMF
TH_1792|M.thermoresistible__bu FTLTEQEPAGDQQRALADVRIDPADLISADPNWVAVLAWQGGVDNNRGIF
MAB_1632c|M.abscessus_ATCC_199 ITLNDLSNDGGRRMVSADVVINPHDLISDDPEWVTILSWQGGLANDHGLA
MSMEG_6500|M.smegmatis_MC2_155 IALTDAAGAGEQRMVDADVRITPADLISDDPEWVSLLSWQGGLDNQRGLL
MAV_3198|M.avium_104 ILLTDLPSPPGQRMVSADIQLMPADMVSPDPEWVTVLSWQGRMQNHRGLQ
MMAR_5199|M.marinum_M LLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTGGFWRVLGIR
MUL_4272|M.ulcerans_Agy99 LLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTGGFWRVLGIR
. : * : : : :. :. * . . *
Mvan_5724|M.vanbaalenii_PYR-1 VDHLEKVGVGHYRSTEPMPVSGTWKTLLRVHDGRTLTAVPIYLAGDPGIG
Mflv_1094|M.gilvum_PYR-GCK LDHLDEVGPGHFRSTEPMPVSGTWKTLLRVHDGSTLTAVPIYLHGDPGIG
TH_1792|M.thermoresistible__bu IDHLERVGPGHYRSTEPMPVSGTWKTLLRVHDGRTLAAVPIYLAGDPGIG
MAB_1632c|M.abscessus_ATCC_199 IDTLRKISEGHYRSTQPIPVYGSWKTLLRVQDGTTMTGVPIFLPADPGIG
MSMEG_6500|M.smegmatis_MC2_155 VNHLERVGPGHYRTTQPMPVSGSWKTLLRVQDGTTMAGVPIYLPADPGIG
MAV_3198|M.avium_104 IDHLARVGPGHYRSTQPLPVWGTWKTLLRVQDGYTMTAVPIYEPADDAIP
MMAR_5199|M.marinum_M LLTAIVVGLVGGAISAPFGIVG--QILLGATASEGSTGMFLVGMTLSSIG
MUL_4272|M.ulcerans_Agy99 LLTAIVVGLVGGAISAPFGIVG--QILLGATASEGSTGMFLVGMTLSSIG
: :. : *: : * : ** . . :.: : .*
Mvan_5724|M.vanbaalenii_PYR-1 AEEVPAEAQFTRPFVSEITILQRERSPDIPASLWLIGCLVVLLCTLAMIA
Mflv_1094|M.gilvum_PYR-GCK AEEVPAEAQFTRPFVSEITILQRERSPDIPQALWLIGCLVVLVCSLAMIA
TH_1792|M.thermoresistible__bu AEEVPAEQQFTRPFVAEITILQRERSPDIPESLWLIGCLVVLACTLAMVA
MAB_1632c|M.abscessus_ATCC_199 AQETPALASSTRPFTQELSILQRERNQNHPSWLFEAASLVVLFCTLVLIA
MSMEG_6500|M.smegmatis_MC2_155 AEEQPAEAVSTREFVPEITILQRERNLDHPSWLFGAASLVVLVCTLLLIA
MAV_3198|M.avium_104 AAEVPALSAMNRPFVQEITILQRERDQNAPVWLFTAGSIVVLCLTLMVIA
MMAR_5199|M.marinum_M S---AISQIITAPFTAGVVVL-----------LYTDRRMRAEAFDLVLQT
MUL_4272|M.ulcerans_Agy99 S---AISQIITAPFTAGVVVL-----------LYTDRRMRAEAFDLVLQT
: . . *. : :* *: : . * : :
Mvan_5724|M.vanbaalenii_PYR-1 GISWGAGRINNSE-PSGSEAEFAPSAQS------
Mflv_1094|M.gilvum_PYR-GCK GITWGGGRINNSE-PSGSEAEFQPSAQS------
TH_1792|M.thermoresistible__bu GITWGAGRINNTE-PSGSAAELEPSTQA------
MAB_1632c|M.abscessus_ATCC_199 VLSWGAGRINGTESRSDSDTLPTPGPKEPVPHGK
MSMEG_6500|M.smegmatis_MC2_155 ALTWGAGRVNARELAAGSTTDETR-PVQPQT---
MAV_3198|M.avium_104 SLTWGAGRLNNAVGEPEPVEDKQPIPRAA-----
MMAR_5199|M.marinum_M GAAGGPAAVESTDNLWLTRPL-------------
MUL_4272|M.ulcerans_Agy99 GAAGGPAAVESTDTLWLTRPL-------------
: * . :: .