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ELSLQAEVLAQGSEGGGAAISEIITLSAAGAVIAVILLWIGWMHRTRKITWLARLGDWSGRRFKRPPWVA LPIGLFISSIICALFGFIWDVSLHIGNGRDDGALANPAHYFILIGLFGIFVAGCTAMVLPLDEKPGVAAV RITDDWYAPVGGIVMAGCGVYALLGFPLDDIWHRIFGQDVTLWGPTHLMMIGGAGFSTLAALYLEYEGRK ARTGAEDVPRDGLGLKFVQYLAFAGVLIGASVYQIEFDFGVPQFRQVFQPMLIAAAAGLALVAARIFMGR GAALIAALIAIGLRGIVALAVGPVLDAPINWFPLYLGAAVVVELVALTPLIRKPILFGLVAGLGIGTVGL YLESLWIGAVYAFPWPTSIWPEGLAMAVPVAILTGGCGALVGMVLTGQRLPSRGISIGLVVLTVLAIGGA AANGLRYDVPQNASASFTLTEAPPVNGERFVTADVRFTPPDVISEDPNWVSVLGWQGGLPNDRGMFLDHL DEVGPGHFRSTEPMPVSGTWKTLLRVHDGSTLTAVPIYLHGDPGIGAEEVPAEAQFTRPFVSEITILQRE RSPDIPQALWLIGCLVVLVCSLAMIAGITWGGGRINNSEPSGSEAEFQPSAQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1094 | - | - | 100% (614) | hypothetical protein Mflv_1094 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1632c | - | 0.0 | 62.35% (603) | hypothetical protein MAB_1632c |
| M. marinum M | MMAR_3034 | - | 8e-05 | 31.79% (173) | transmembrane protein |
| M. avium 104 | MAV_3198 | - | 0.0 | 63.04% (598) | hypothetical protein MAV_3198 |
| M. smegmatis MC2 155 | MSMEG_6500 | - | 0.0 | 64.92% (593) | hypothetical protein MSMEG_6500 |
| M. thermoresistible (build 8) | TH_1792 | - | 0.0 | 79.15% (609) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2274 | - | 5e-05 | 31.79% (173) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_5724 | - | 0.0 | 85.74% (617) | hypothetical protein Mvan_5724 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1094|M.gilvum_PYR-GCK --MELSLQAE-VLAQ--GSEGGGAAISEIITLSAAGAVIAVILLWIGWMH
Mvan_5724|M.vanbaalenii_PYR-1 MTMEFSLQAVSVLAQSSGDEGGGTALSEIVALSAAGAVVTAVLLWIGWQH
TH_1792|M.thermoresistible__bu -----------VLAQ--ADEGGGAALSEIIGLSVAAAVVTLVLLWIGYLH
MAB_1632c|M.abscessus_ATCC_199 -----MTTHSVRIIAAAN-EGGGAALDQVIGMSVAATIVSVGLLWIGYLH
MSMEG_6500|M.smegmatis_MC2_155 ----MVGSSQVSLFAAEGTEGGGAALDQVIGLSAVATVITAALLWIGYLH
MAV_3198|M.avium_104 -----MRSDELTIVAEAP--ARGAGLNQVIGLSLAAVVITLLMLWVGHAH
MMAR_3034|M.marinum_M -MGGLAPRTVVAVVFAVRGSPSKISILPGVQDRLDGVAGSRRGLRIALRG
MUL_2274|M.ulcerans_Agy99 -----------------------------MQDRLDGVAGSRRGLRIALRG
: .. : * :.
Mflv_1094|M.gilvum_PYR-GCK RTRKITWLARLGDWSGRRFKRPPWVALPIGLFISSIICALFGFIWDVSLH
Mvan_5724|M.vanbaalenii_PYR-1 RNHKITWLAGLADWSARRFKRPPWVALPIAMFIASIICALFGFIWDVSLH
TH_1792|M.thermoresistible__bu RSHKITWLTGLGDWAGRRFKRPSWVALPIALFIASIICALFGFIWDVSLH
MAB_1632c|M.abscessus_ATCC_199 RQRRITWLQSLADKVGNKFNRPPWVALQICLFVTTIVAALFGFIWDVSLH
MSMEG_6500|M.smegmatis_MC2_155 RQRRITWLNNFAERLGRKFHRPPWVALQIFLFTSTIICALFGFIWDVSLH
MAV_3198|M.avium_104 RTHRIQWLTRIADKMGEKFHRPNWVALPVLIFTTSIICALFGFIWDVSWH
MMAR_3034|M.marinum_M RRDPVPVAGQRSRTSSGMGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MUL_2274|M.ulcerans_Agy99 RRDPVPVAGQRSRTSSGMGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
* : . . .: .* : : : :: : . **
Mflv_1094|M.gilvum_PYR-GCK IGNGRDDGALANPAHYFILIGLFGIFVAGCTAMVLPLDE---KPGVAAVR
Mvan_5724|M.vanbaalenii_PYR-1 IGNGRDDGALANPAHYFILIGLFGIFVAGCTAMVLPYD----RPGPAAVR
TH_1792|M.thermoresistible__bu IGNGRDDGALANPAHYFILIGLFGIFVAGCTAMVLPLGGADAKPGPSAVR
MAB_1632c|M.abscessus_ATCC_199 IGKGRDAGPLANPAHYFILFGLFLLFIAGTLAMVLPYD----KPGSAAVR
MSMEG_6500|M.smegmatis_MC2_155 IGQGRDEGPLANPAHYFILVGLFLLFIAGVLAMVLPYE----KPGPAAIR
MAV_3198|M.avium_104 IGNGRDPGPLANPAHYFIIIGLFGVFLGGMVSVVLPFD----KPGPAAVR
MMAR_3034|M.marinum_M ANDVAQAYQITDCVVDITVTTIIVSALPTAESAPVTIVR--------SVR
MUL_2274|M.ulcerans_Agy99 ANDVAQAYQITDCVVDITVTTIIVSALPTAESTPVTIVR--------SVR
.. : ::: . : : :: : : :. ::*
Mflv_1094|M.gilvum_PYR-GCK ITDDWYAPVGGIVMAGCGVYALLGFPLDDIWHRIFGQDVTLWG-PTHLMM
Mvan_5724|M.vanbaalenii_PYR-1 ITDDWYAPVGGIVMAGCGLYALLGFPLDDMWHRIFGQDVTLWG-PTHLMM
TH_1792|M.thermoresistible__bu ITDHWYAPVGGIVMAGCGLYALMGFPLDDMWHRIFGQDVTLWG-PTHLMM
MAB_1632c|M.abscessus_ATCC_199 ITRTWYAPVGGLLMAMCGLYALIGFPLDDIWHRIFGQDVTLWG-PTHLML
MSMEG_6500|M.smegmatis_MC2_155 ITRTWYAPVGGVLMALCGLYALIGFPLDDIWHRIFGQDVTLWG-PTHLML
MAV_3198|M.avium_104 ITRNWYAPVGGVLMAGCGLYAMIGFPLDDIWHRIFGQDVTLWG-PTHLMM
MMAR_3034|M.marinum_M TRSTNFTRLAELDRLVQEITAG-GVTVDEAHEAMDELTQRPHPYPRWLAT
MUL_2274|M.ulcerans_Agy99 TRSTNFTRLAELDRLVQEITAG-GVTVDEAHEAMDELTQRPHPYPRWLAT
:: :. : : * *..:*: . : * *
Mflv_1094|M.gilvum_PYR-GCK IGGAGFSTLAALYLEYEGRKARTGAEDVPR-----DGLGLKFVQYLAFAG
Mvan_5724|M.vanbaalenii_PYR-1 IGGAGFSTLAALYLEYEGRRVRT--DETPP-----DGIGLKFVQYLAFAG
TH_1792|M.thermoresistible__bu IGGAGFSTLAAAYLELEGKRVRG--PDTPP-----DGPGLKFIQYLAFAG
MAB_1632c|M.abscessus_ATCC_199 IGGAGLSLVSVLILEYEGRRAIG--FSAD-----DDTRFVKFLRYLSFGG
MSMEG_6500|M.smegmatis_MC2_155 IGGAGLSLIAVLLLEHEGRVAMA--GNSSPGDIKDDTRFNTFLRYLSFGG
MAV_3198|M.avium_104 IGGAGFSLFAVLMLEREGEAAEG--EDVY------HSVFIRFLRYLSFGG
MMAR_3034|M.marinum_M VCWAGFSLGIAMMLGANWRTCAI--------------------------A
MUL_2274|M.ulcerans_Agy99 VCWAGFSLGIAMMLGANWRTCAI--------------------------A
: **:* . * : . .
Mflv_1094|M.gilvum_PYR-GCK VLIGASVYQIEFDFGVPQFRQVFQPMLIAAAAGLALVAARIFMGRGAALI
Mvan_5724|M.vanbaalenii_PYR-1 VLIGASVYQIEFDFGVPQFRQVFQPMLIAAAAALALVAARIFMGRGAALI
TH_1792|M.thermoresistible__bu VLIGASVYQIEFDFGVPQFRQVFQPMLIAAAAALALVGARIFLGRGAAII
MAB_1632c|M.abscessus_ATCC_199 LFIGLSVFQIEYDFGVEQFRLVQQPMMIAAAAAFAAVCARIVMGRGAAII
MSMEG_6500|M.smegmatis_MC2_155 LFIGLSVFQIEYDFGVEQFRLVLQPMMIAGAAALAAVAARLVLGPGAAVI
MAV_3198|M.avium_104 MFIGLSVFQIEYDFGVEQFRLVLQPMMIAGAAALAAVAARITMGRGAALI
MMAR_3034|M.marinum_M ALTAATIDRLGRVLNRIGTPYFFQRVTGAAVATLVAVAAYLFTGEGLAAL
MUL_2274|M.ulcerans_Agy99 ALTAATIDRLGRVLNRIGTPYFFQRVTGAAVATLVAVAAYLFTGEGLAAL
: . :: :: :. . * : *..* :. * * : * * * :
Mflv_1094|M.gilvum_PYR-GCK AALIAIGLRGIVALAVGPVLDAPINWFPLYLGAAVVVELVALTPLIRKPI
Mvan_5724|M.vanbaalenii_PYR-1 AALIAIGLRGLVAVAVGPVLDAPLNWFPLYLGAALVVEILALTPLLRRPV
TH_1792|M.thermoresistible__bu AALVAIGLRGIVALLVGPILGEPINWFPLYLGAAVVVELLALTPLFRRRV
MAB_1632c|M.abscessus_ATCC_199 GALLAIVLRAAVALLAGPILGGPTSWFALYLGPALVVELIALTPLIKRPI
MSMEG_6500|M.smegmatis_MC2_155 AAVLAIVLRGAVSLAVGPVLGAPHSWWALYLGPALVVELVALTPLVKRPL
MAV_3198|M.avium_104 AAVFAIALRGAVAVLVGPVLGAPLNWFPLYLGPALAVELVALTPIFKRPI
MMAR_3034|M.marinum_M VATGIVMLLSGLTLVG--AMQDAITGY-----MVTAVARIGEALFLTSGI
MUL_2274|M.ulcerans_Agy99 VATGIVMLLSGLTLVG--AMQDAITGY-----MVTAVARIGEALFLTSGI
* : * . ::: : . . : . .* :. : :. :
Mflv_1094|M.gilvum_PYR-GCK LFGLVAGLGIGTVGLYLESLWIGAVYAFPWPTSIWPEGLAMAVPVAILTG
Mvan_5724|M.vanbaalenii_PYR-1 LFGLVSGLGIGTVGLWLESLWIGAVYPYPWPTSIWPEALAMSVPVAVLTG
TH_1792|M.thermoresistible__bu LFGLVSGLGIATVGLWLESLWIGTVYHLPWPAGIWPEALAMSIPVAVLTG
MAB_1632c|M.abscessus_ATCC_199 LFGALAGLGVGTAGLWLESLWIGAVYRYPWPVSMWPEALAMAVPAAIAMG
MSMEG_6500|M.smegmatis_MC2_155 VFGAVSGLAVATVGLWLESLWIGAVYTYPWPTSMWGEALAMSIPVAVGMG
MAV_3198|M.avium_104 VFGAVSGLGVGTLGLWLESLWISAVYHYPWPVSMWAEALAMAVPVAVLMG
MMAR_3034|M.marinum_M VVGILAGLQIAKTAGVEIELRVHGSGGFVVPQ--GPLPILLTVLGAMLAG
MUL_2274|M.ulcerans_Agy99 VVGILAGLQIAKTAGVEIELRVHGSGGFVVPQ--GPLPILLTVLGAMLAG
:.* ::** :.. . .* : * : ::: *: *
Mflv_1094|M.gilvum_PYR-GCK GCGALVGMVLTGQRLPSRGISIGLVVLTVLAIGGAAANGLRYDVPQNASA
Mvan_5724|M.vanbaalenii_PYR-1 GCGAMVGMVLTGRRLPGRAVGIGLVALTVLAIGGAAANGLRYDTPQNATA
TH_1792|M.thermoresistible__bu ACGAMLGMVLTEERLPRRAVGVGLVALTVLAIGGATANGLRYDVPETATA
MAB_1632c|M.abscessus_ATCC_199 ICGALLGMVLIGQKLPARPVSITAVVLTVLILGAAVANGLRTEVPERATA
MSMEG_6500|M.smegmatis_MC2_155 LCGALLALVLTSRRLPRPAVGISIVVATVLAIGGAVANGLRIEVPENATA
MAV_3198|M.avium_104 MCGAMFGMVLTGQRLPGRAIGISVVVATVLVIGGAVANGLHIVVPRQNNA
MMAR_3034|M.marinum_M ACLTVASYAPLRSAVTAG-FAAGLADLVLIGLG-TAGFGQVIATGIAAVG
MUL_2274|M.ulcerans_Agy99 ACLTVASYAPLRSAVTAG-FAAGLADLVLIGLG-TAGFGQVIATGIAAVG
* :: . . :. .. . .:: :* :.. * . .
Mflv_1094|M.gilvum_PYR-GCK SFTLTEAPPVNGERFVTADVRFTPPDVISEDPNWVSVLGWQGGLPNDRGM
Mvan_5724|M.vanbaalenii_PYR-1 SVTLTEAPAVDGQRFVTADVRFNPPDVIGDNPNWVSVLGWQGGLPNERGQ
TH_1792|M.thermoresistible__bu TFTLTEQEPAGDQQRALADVRIDPADLISADPNWVAVLAWQGGVDNNRGI
MAB_1632c|M.abscessus_ATCC_199 TITLNDLSNDGGRRMVSADVVINPHDLISDDPEWVTILSWQGGLANDHGL
MSMEG_6500|M.smegmatis_MC2_155 TIALTDAAGAGEQRMVDADVRITPADLISDDPEWVSLLSWQGGLDNQRGL
MAV_3198|M.avium_104 TILLTDLPSPPGQRMVSADIQLMPADMVSPDPEWVTVLSWQGRMQNHRGL
MMAR_3034|M.marinum_M VGFLATLISIRRQALALVTATAGIVPMLPGLAVFRAVFYFAADS------
MUL_2274|M.ulcerans_Agy99 VGFLATLISIRRQALALVTATAGIVPMLPGLAVFRAVFYFAADS------
* . . . :: . : ::: : .
Mflv_1094|M.gilvum_PYR-GCK FLDHLDEVGPGHFRSTEPMPVSGTWKTLLRVHDGSTLTAVPIYLHGDPGI
Mvan_5724|M.vanbaalenii_PYR-1 FVDHLEKVGVGHYRSTEPMPVSGTWKTLLRVHDGRTLTAVPIYLAGDPGI
TH_1792|M.thermoresistible__bu FIDHLERVGPGHYRSTEPMPVSGTWKTLLRVHDGRTLAAVPIYLAGDPGI
MAB_1632c|M.abscessus_ATCC_199 AIDTLRKISEGHYRSTQPIPVYGSWKTLLRVQDGTTMTGVPIFLPADPGI
MSMEG_6500|M.smegmatis_MC2_155 LVNHLERVGPGHYRTTQPMPVSGSWKTLLRVQDGTTMAGVPIYLPADPGI
MAV_3198|M.avium_104 QIDHLARVGPGHYRSTQPLPVWGTWKTLLRVQDGYTMTAVPIYEPADDAI
MMAR_3034|M.marinum_M ---HFDEAQSQLLSAAATALALGSGVVLG------EFVGSPLRYRAG-RI
MUL_2274|M.ulcerans_Agy99 ---HFDEAQSQLLSAAATALALGSGVVLG------EFVGSPLRYRAG-RI
: . :: . . *: .* :.. *: .. *
Mflv_1094|M.gilvum_PYR-GCK GAEEVPAEAQFTRPFVSEITILQRERSPDIPQALWLIGCLVVLVCSLAMI
Mvan_5724|M.vanbaalenii_PYR-1 GAEEVPAEAQFTRPFVSEITILQRERSPDIPASLWLIGCLVVLLCTLAMI
TH_1792|M.thermoresistible__bu GAEEVPAEQQFTRPFVAEITILQRERSPDIPESLWLIGCLVVLACTLAMV
MAB_1632c|M.abscessus_ATCC_199 GAQETPALASSTRPFTQELSILQRERNQNHPSWLFEAASLVVLFCTLVLI
MSMEG_6500|M.smegmatis_MC2_155 GAEEQPAEAVSTREFVPEITILQRERNLDHPSWLFGAASLVVLVCTLLLI
MAV_3198|M.avium_104 PAAEVPALSAMNRPFVQEITILQRERDQNAPVWLFTAGSIVVLCLTLMVI
MMAR_3034|M.marinum_M GHLLRIEGPPGLRRAVGRVVRLEPTKNAQSTNTRGQQSRSVALEPASTDH
MUL_2274|M.ulcerans_Agy99 GHLLRIEGPPGLRRAVGRVVRLEPTKNAQSTNTRGQQSRSVALEPASTDH
* . .: *: :. : . . *.* :
Mflv_1094|M.gilvum_PYR-GCK AGITWGGGRINNSE-PSGSEAEFQPSAQS------
Mvan_5724|M.vanbaalenii_PYR-1 AGISWGAGRINNSE-PSGSEAEFAPSAQS------
TH_1792|M.thermoresistible__bu AGITWGAGRINNTE-PSGSAAELEPSTQA------
MAB_1632c|M.abscessus_ATCC_199 AVLSWGAGRINGTESRSDSDTLPTPGPKEPVPHGK
MSMEG_6500|M.smegmatis_MC2_155 AALTWGAGRVNARELAAGSTTDETR-PVQPQT---
MAV_3198|M.avium_104 ASLTWGAGRLNNAVGEPEPVEDKQPIPRAA-----
MMAR_3034|M.marinum_M SDAAEDNDRTGGHGGHGGHGGHRDES---------
MUL_2274|M.ulcerans_Agy99 SDAAEDNDRTGGHGGHGGHGGHRDES---------
: : . .* .