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MRGGYRECTLTGKVVPVTNSPGAGRFAPSPSADLHIGNLRTAVLAWLFARSTGRRFLMRVEDLDDRTHTD IADRQLADLAALGVTWDGPAIWQSEHPERYDAVVDTLDERGLLFECYCTRRDIAQAPRAPHAPEGAYPGT CRNLDNADRERRRRETGRPPALRLRTDTTEYTVHDVLHGDYTGLVDDFVVRRGDGVPAYNLAVVVDDAAT GVDQVVRGDDLLSSSPRQAYLARLLGHPEPVYAHVPLVLNGDGARLAKRDGAVTLAEIGVAQALRQIADS LGYEAHAVGGMLDEFDPRRLPRVPWVYRPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5575 | - | - | 100% (310) | glutamyl-Q tRNA(Asp) synthetase |
| M. vanbaalenii PYR-1 | Mvan_2133 | gltX | 9e-33 | 37.01% (254) | glutamyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3016c | gltX | 8e-30 | 35.83% (254) | glutamyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_1233 | - | 1e-149 | 87.03% (293) | glutamyl-Q tRNA(Asp) synthetase |
| M. tuberculosis H37Rv | Rv2992c | gltX | 8e-30 | 35.83% (254) | glutamyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_01688 | gltX | 3e-28 | 35.04% (254) | glutamyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_0278c | - | 1e-115 | 68.28% (290) | glutamyl-Q tRNA(Asp) synthetase |
| M. marinum M | MMAR_1719 | gltX | 8e-31 | 35.88% (262) | glutamyl-tRNA synthetase GltS |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6306 | gltX | 1e-132 | 77.59% (290) | glutamyl-Q tRNA(Asp) synthetase |
| M. thermoresistible (build 8) | TH_1673 | gltX | 1e-123 | 73.20% (291) | glutamyl-tRNA synthetase |
| M. ulcerans Agy99 | MUL_1957 | gltX | 4e-26 | 35.00% (240) | glutamyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5575|M.vanbaalenii_PYR-1 MRGGYRECTLTGKVVPVTNSPGAGRFAPSPSADLHIGNLRTAVLAWLFAR
Mflv_1233|M.gilvum_PYR-GCK MRS--------------TRTAGAGRFAPSPSADLHIGNLRTAVLAWLFAR
MSMEG_6306|M.smegmatis_MC2_155 ------------------MSNAAGRFAPSPSADLHIGNLRTAVLAWLFAR
TH_1673|M.thermoresistible__bu -------------MARVSSSPGAGRFAPSPSADLHIGNLRTAVLAWLFAR
MAB_0278c|M.abscessus_ATCC_199 -------------------MTGAGRFAPSPSGDLHIGNLRTALLAWLLAH
Mb3016c|M.bovis_AF2122/97 ---------------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYAR
Rv2992c|M.tuberculosis_H37Rv ---------------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYAR
MMAR_1719|M.marinum_M ----------------MTSSSVRVRFCPSPTGIPHVGMVRTALFNWAYAR
MUL_1957|M.ulcerans_Agy99 -------------------------------------MVRTALFNWAYAR
MLBr_01688|M.leprae_Br4923 -------MTAVTSDGTPQAAKVRVRFCPSPTGVPHVGMVRTALFNWAYAR
:***:: * *:
Mvan_5575|M.vanbaalenii_PYR-1 STGRRFLMRVEDLDD-RTHTDIADRQLADLAALGVTWDGP--------AI
Mflv_1233|M.gilvum_PYR-GCK STGRRFLMRVEDLDD-RTHTDIADRQLADLAALGITWDGD--------AT
MSMEG_6306|M.smegmatis_MC2_155 STGRRFLVRVEDLDD-RTFPEIGRRQVADLAAVGLTWDEP--------VE
TH_1673|M.thermoresistible__bu STGRRFLIRVEDLDE-RTDAGTAARQLRDLEAIGLTWDGP--------VV
MAB_0278c|M.abscessus_ATCC_199 STGRRFLMRVEDLDT-RTSSAVAQRQLADLAAIGVRWELP--------VV
Mb3016c|M.bovis_AF2122/97 HTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPY
Rv2992c|M.tuberculosis_H37Rv HTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPY
MMAR_1719|M.marinum_M HTGGTFVFRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPY
MUL_1957|M.ulcerans_Agy99 HTGGTFVFRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPY
MLBr_01688|M.leprae_Br4923 HTGGTFVLRIEDTDADRDSEESYLALLDALRWLGLNWDEGPEVGGPYGPY
** *:.*:** * * : * :*: *:
Mvan_5575|M.vanbaalenii_PYR-1 WQSEHPERYDAVVDTLDERGLLFECYCTRRDIAQAPRAP-HAPEGAYPGT
Mflv_1233|M.gilvum_PYR-GCK RQTDHPERYDAVVDGLAGSGLLFECYCTRRDIAQAPRAP-HAPEGAYPGT
MSMEG_6306|M.smegmatis_MC2_155 WQTTHEDRYDAVIDQLAGEGLLYECYCSRKDIAQAPRAP-HAPQGAYPGT
TH_1673|M.thermoresistible__bu WQSRRRPIYQAVVDKLVADDLVYECYCSRKDIAQAPRAP-HAPQGAYPGT
MAB_0278c|M.abscessus_ATCC_199 WQSDRAPAYDEVIASLASRHLLYECYCSRKDIAQAPTAP-HAPPGAYPGT
Mb3016c|M.bovis_AF2122/97 RQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNF
Rv2992c|M.tuberculosis_H37Rv RQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNF
MMAR_1719|M.marinum_M RQSQRTEIYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNF
MUL_1957|M.ulcerans_Agy99 RQSQRTEIYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNF
MLBr_01688|M.leprae_Br4923 RQSQRTDIYREVVAKLLATGEAYYAFSTPEEVENRHLAAGRNPKLGYDNF
*: : * *: * : .:.: .:: *. : * .* .
Mvan_5575|M.vanbaalenii_PYR-1 CRNLDNADRERRRRETG-RPPALRLRTDTTEYTVHDVLHG---DYTGLVD
Mflv_1233|M.gilvum_PYR-GCK CRDLTDAERDQRRDETG-RPPALRLRTDTTSHTVHDVLHG---DYTGLVD
MSMEG_6306|M.smegmatis_MC2_155 CRDLTDDERAARRRETG-RPPAMRLRTDTFVYTVNDVLHG---PYTGIVD
TH_1673|M.thermoresistible__bu CRDLTRSRRERRRRETG-RPPALRLRTDVTHHAVTDLLHG---SYHGHVD
MAB_0278c|M.abscessus_ATCC_199 CRDLSESERAQRRLDRAQRPPALRLRTENSPFTVQDLLHG---EYTGLVD
Mb3016c|M.bovis_AF2122/97 DRHLTDAQRAAYLAEGR--QPVVRLRMPDDDLAWNDLVRGPVTFAAGSVP
Rv2992c|M.tuberculosis_H37Rv DRHLTDAQRAAYLAEGR--QPVVRLRMPDDDLAWNDLVRGPVTFAAGSVP
MMAR_1719|M.marinum_M DRQLTDSQRAAYLAEGR--KPVVRLRMPDTDLAWHDLVRGPTTFAAGSVP
MUL_1957|M.ulcerans_Agy99 DRQLTDSQRAAYLAEGR--KPVVRLRMPDTDLAWHDLVRGPTTFAAGSVP
MLBr_01688|M.leprae_Br4923 DRDLTDAQFSAYLAEGR--KPVVRLRMPDEDISWDDLVRGTTTFAVGTVP
*.* : *.:*** : *:::* * *
Mvan_5575|M.vanbaalenii_PYR-1 DFVVRRGDGVPAYNLAVVVDDAATGVDQVVRGDDLLSSSPRQAYLARLLG
Mflv_1233|M.gilvum_PYR-GCK DFVVRRGDGVPAYNLAVVVDDAASGIDQVVRGDDLLSSSPRQAYLARLLG
MSMEG_6306|M.smegmatis_MC2_155 DFVVRRGDGVPAYNLAVVVDDAASGIDQVVRGDDLLPSSPRQAYLARLLG
TH_1673|M.thermoresistible__bu DFVVLRGDGVPAYNLAVVVDDAAQGIDQVVRGDDLLSSAPRQAYLARLLG
MAB_0278c|M.abscessus_ATCC_199 DFVVRRGDGVTAYNVAVVIDDHAQGIDQVVRGEDLLASAPRQAYLAALLG
Mb3016c|M.bovis_AF2122/97 DFALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALI
Rv2992c|M.tuberculosis_H37Rv DFALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALI
MMAR_1719|M.marinum_M DFALTRATGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALM
MUL_1957|M.ulcerans_Agy99 DFALTRATGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALM
MLBr_01688|M.leprae_Br4923 DYVLTRASGDPLYTLVNPCDDALMKITHVLRGEDLLSSTPRQVALYQALI
*:.: *. * . *.:. ** : :*:**:***.*:*** * *
Mvan_5575|M.vanbaalenii_PYR-1 -----HPEPVYAHVPLVLNGDGARLAKRDGAVTLAEIG----VAQALRQI
Mflv_1233|M.gilvum_PYR-GCK -----HPEPVYAHVPLVLNADGARLAKRDGAVTLAEIG----LSKALAQI
MSMEG_6306|M.smegmatis_MC2_155 -----HPEPTYAHVPLVLNEDGARLAKRDGAVTLAEIG----VERAFAQI
TH_1673|M.thermoresistible__bu -----HRPPQYAHVPLVLNTAGKRLAKRDGAVTLPELG----VRRAFELI
MAB_0278c|M.abscessus_ATCC_199 -----YPAPTYAHVPLVLNTAGARLAKRDGAVTLADLG----AQRAFAMI
Mb3016c|M.bovis_AF2122/97 RIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNY
Rv2992c|M.tuberculosis_H37Rv RIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNY
MMAR_1719|M.marinum_M RIGIAERVPEFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNY
MUL_1957|M.ulcerans_Agy99 CIGIAERVPEFAHLPTVLGEETKKLSKRDPQSNLFAHRDRGFIPEGLLNY
MLBr_01688|M.leprae_Br4923 RIGMAERIPEFGHFPSVLGEGTKKLSKREPQSNLFAHRDRGFIPEGLLNY
* :.*.* **. :*:**: .* ..:
Mvan_5575|M.vanbaalenii_PYR-1 ADSLGYEAHA------VGGMLDEFDPRRLPRVPWVYRPG-----------
Mflv_1233|M.gilvum_PYR-GCK ADSLGYAARS------VEAMLDEFDPQRLPRQAWVYQPG-----------
MSMEG_6306|M.smegmatis_MC2_155 TESLGRPATT------MDELLARFDPDQLPRHPWIYRPV-----------
TH_1673|M.thermoresistible__bu SASLGWPASN------LAELLDQFDPAALPRSPWIWPATP----------
MAB_0278c|M.abscessus_ATCC_199 CDSLGYQAAD------ATDLLRQFDAGRIPREPWIYPG------------
Mb3016c|M.bovis_AF2122/97 LALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIR
Rv2992c|M.tuberculosis_H37Rv LALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIR
MMAR_1719|M.marinum_M LALLGWAIADDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIR
MUL_1957|M.ulcerans_Agy99 LALLGWAIADDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIR
MLBr_01688|M.leprae_Br4923 LALLGWAIADDHDLFSLDEMVAAFDVVDVNSNPARFDQKKADAVNAEHIR
** :: ** : . :
Mvan_5575|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1233|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6306|M.smegmatis_MC2_155 --------------------------------------------------
TH_1673|M.thermoresistible__bu --------------------------------------------------
MAB_0278c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3016c|M.bovis_AF2122/97 MLDVGDFTVRLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDA
Rv2992c|M.tuberculosis_H37Rv MLDVGDFTVRLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDA
MMAR_1719|M.marinum_M MLDVADFTARLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDA
MUL_1957|M.ulcerans_Agy99 MLDVADFTARLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDA
MLBr_01688|M.leprae_Br4923 MLDSEDFAGRLRDYFTTHGYHIALDPANYEAGFVAAAQLVQTRIVVLGDA
Mvan_5575|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1233|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6306|M.smegmatis_MC2_155 --------------------------------------------------
TH_1673|M.thermoresistible__bu --------------------------------------------------
MAB_0278c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3016c|M.bovis_AF2122/97 WELLKFFNDDQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIE
Rv2992c|M.tuberculosis_H37Rv WELLKFFNDDQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIE
MMAR_1719|M.marinum_M WALLKFLNDDRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIE
MUL_1957|M.ulcerans_Agy99 WALLKFLNDDRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIE
MLBr_01688|M.leprae_Br4923 WDLLKFLNDDEYSIDSKAAAKELDADAGPVLDVACAVLDSLVDWTTASIE
Mvan_5575|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1233|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6306|M.smegmatis_MC2_155 --------------------------------------------------
TH_1673|M.thermoresistible__bu --------------------------------------------------
MAB_0278c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3016c|M.bovis_AF2122/97 AALKDALIEGLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQR
Rv2992c|M.tuberculosis_H37Rv AALKDALIEGLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQR
MMAR_1719|M.marinum_M AALKTALIEGMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGR
MUL_1957|M.ulcerans_Agy99 AALKTALIGGMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGR
MLBr_01688|M.leprae_Br4923 DVLKVALIEGLGLKPRKVFGPIRVAATGALVSPPLFESLELLGRARSLQR
Mvan_5575|M.vanbaalenii_PYR-1 -----------
Mflv_1233|M.gilvum_PYR-GCK -----------
MSMEG_6306|M.smegmatis_MC2_155 -----------
TH_1673|M.thermoresistible__bu -----------
MAB_0278c|M.abscessus_ATCC_199 -----------
Mb3016c|M.bovis_AF2122/97 LRAARQLVGHA
Rv2992c|M.tuberculosis_H37Rv LRAARQLVGHA
MMAR_1719|M.marinum_M LRSARDQVGSP
MUL_1957|M.ulcerans_Agy99 LRSARDQVGSP
MLBr_01688|M.leprae_Br4923 LSAARARVTSA