For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb3016c (gltX)

annotation: glutamyl-tRNA synthetase
coordinates: 3305365 - 3306837
length: 490

VTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGL
DWDEGPEVGGPYGPYRQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLT
DAQRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASGDPLYTLVNPCDDALMKIT
HVLRGEDLLPSTPRQLALHQALIRIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGL
LNYLALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTVRLRDHLDT
HGHHIALDEAAFAAAAELVQTRIVVLGDAWELLKFFNDDQYVIDPKAAAKELGPDGAAVLDAALAALTSV
TDWTAPLIEAALKDALIEGLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVGHA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3016cgltX-100% (490)glutamyl-tRNA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4229gltX0.078.66% (478) glutamyl-tRNA synthetase
M. tuberculosis H37RvRv2992cgltX0.0100.00% (490) glutamyl-tRNA synthetase
M. leprae Br4923MLBr_01688gltX0.081.35% (488) glutamyl-tRNA synthetase
M. abscessus ATCC 19977MAB_3298cgltX0.078.66% (478) glutamyl-tRNA synthetase
M. marinum MMMAR_1719gltX0.086.80% (485) glutamyl-tRNA synthetase GltS
M. avium 104-----
M. smegmatis MC2 155MSMEG_2383gltX0.081.61% (484) glutamyl-tRNA synthetase
M. thermoresistible (build 8)TH_2041gltS0.076.57% (478) PROBABLE GLUTAMYL-TRNA SYNTHETASE GLTS (GLUTAMATE--TRNA
M. ulcerans Agy99MUL_1957gltX0.086.48% (466) glutamyl-tRNA synthetase
M. vanbaalenii PYR-1Mvan_2133gltX0.078.51% (484) glutamyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_3298c|M.abscessus_ATCC_199      ---------MSNTKIRVRFCPSPTGTPHVGLIRTALFNWAYARHCGGDFV
MSMEG_2383|M.smegmatis_MC2_155      ---------MTTKKVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGDFV
Mflv_4229|M.gilvum_PYR-GCK          ------------MKVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGDFV
Mvan_2133|M.vanbaalenii_PYR-1       --------MTTSDVVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGTFV
TH_2041|M.thermoresistible__bu      ----MTEPTDGSTKVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGTFV
Mb3016c|M.bovis_AF2122/97           --------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFV
Rv2992c|M.tuberculosis_H37Rv        --------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFV
MMAR_1719|M.marinum_M               ---------MTSSSVRVRFCPSPTGIPHVGMVRTALFNWAYARHTGGTFV
MUL_1957|M.ulcerans_Agy99           ------------------------------MVRTALFNWAYARHTGGTFV
MLBr_01688|M.leprae_Br4923          MTAVTSDGTPQAAKVRVRFCPSPTGVPHVGMVRTALFNWAYARHTGGTFV
                                                                  ::************ ** **

MAB_3298c|M.abscessus_ATCC_199      FRIEDTDAGRDSEESYLAILDALRWLGLDWDEGPEVGGPYEPYRQSQRKE
MSMEG_2383|M.smegmatis_MC2_155      FRIEDTDAARDSDESYAAILDALRWLGMDWDEGPEVGGPYEPYRQSQRRE
Mflv_4229|M.gilvum_PYR-GCK          FRIEDTDAQRDSEESYLALLDALRWLGMDWDEGPEVGGPYAPYRQSQRRD
Mvan_2133|M.vanbaalenii_PYR-1       FRIEDTDSARDSEDSYLALLDALRWLGMDWDEGPEIGGPYGPYRQSQRLD
TH_2041|M.thermoresistible__bu      FRIEDTDSARDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSERLH
Mb3016c|M.bovis_AF2122/97           FRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAE
Rv2992c|M.tuberculosis_H37Rv        FRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAE
MMAR_1719|M.marinum_M               FRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPYRQSQRTE
MUL_1957|M.ulcerans_Agy99           FRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPYRQSQRTE
MLBr_01688|M.leprae_Br4923          LRIEDTDADRDSEESYLALLDALRWLGLNWDEGPEVGGPYGPYRQSQRTD
                                    :******: ***::** *:********::******:.*** *****:* .

MAB_3298c|M.abscessus_ATCC_199      LHREVVRKLLEAGEAYEAFSTAEEVEARHLAAGRNPKLGYDNYDRDLTEE
MSMEG_2383|M.smegmatis_MC2_155      IYRDVVARLLEAGEVYEAYSTPEEVEARHLAAGRNPKLGYDNYDRDLTDA
Mflv_4229|M.gilvum_PYR-GCK          LYLDVIRRLLAAGEAYEAFSTAEEVEARHLAAGRNPKLGYDNFDRDLTEE
Mvan_2133|M.vanbaalenii_PYR-1       IYTDVIERLLAAGEAYEAFSTAEEVEARHIAAGRNPKLGYDNYDRDLTEE
TH_2041|M.thermoresistible__bu      IYRDVIERLLESGAAYESFSTPEEVEARHRAAGRNPKLGYDNFDRDLTEE
Mb3016c|M.bovis_AF2122/97           IYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDA
Rv2992c|M.tuberculosis_H37Rv        IYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDA
MMAR_1719|M.marinum_M               IYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNFDRQLTDS
MUL_1957|M.ulcerans_Agy99           IYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNFDRQLTDS
MLBr_01688|M.leprae_Br4923          IYREVVAKLLATGEAYYAFSTPEEVENRHLAAGRNPKLGYDNFDRDLTDA
                                    :: :*: :** :* .* ::**.**** ** ************:**.**: 

MAB_3298c|M.abscessus_ATCC_199      QRAAFRAEGRDPVVRLRMPDHDITWNDLVRGETTFAAGVVPDFALTRGNG
MSMEG_2383|M.smegmatis_MC2_155      QRKAFADEGRRPVLRLRMPDEDLSWNDLVRGPTTFAAGSVPDFAITRSNG
Mflv_4229|M.gilvum_PYR-GCK          QRAAFRAEGRQPVVRLRMPDADMTWVDLVRGETTFPVGSVPDFALTRGSG
Mvan_2133|M.vanbaalenii_PYR-1       QRAAFRAEGRRPVVRLRMPDTDLTWVDLVRGETTFPAGSVPDFALTRGNG
TH_2041|M.thermoresistible__bu      QRRAYRAEGRRPVIRLKMPDRDIGWRDLVRGETTFPAGTLADFALTRSNG
Mb3016c|M.bovis_AF2122/97           QRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASG
Rv2992c|M.tuberculosis_H37Rv        QRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASG
MMAR_1719|M.marinum_M               QRAAYLAEGRKPVVRLRMPDTDLAWHDLVRGPTTFAAGSVPDFALTRATG
MUL_1957|M.ulcerans_Agy99           QRAAYLAEGRKPVVRLRMPDTDLAWHDLVRGPTTFAAGSVPDFALTRATG
MLBr_01688|M.leprae_Br4923          QFSAYLAEGRKPVVRLRMPDEDISWDDLVRGTTTFAVGTVPDYVLTRASG
                                    *  *:  *** **:**:*** *: * ***** .**..* :.*:.:**..*

MAB_3298c|M.abscessus_ATCC_199      DPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQIALYEAMIRIGVTDSIP
MSMEG_2383|M.smegmatis_MC2_155      DPLYTLVNPVDDALMKITHVLRGEDILPSTPRQIALYRALMRIGVAEFVP
Mflv_4229|M.gilvum_PYR-GCK          DPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQLALYAALIRIGVTDMTP
Mvan_2133|M.vanbaalenii_PYR-1       EPLYPLVNPVDDALMKITHVLRGEDLLPSTPRQLALYGALIRIGVADTTP
TH_2041|M.thermoresistible__bu      EPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQIALYEALMAIGVADTVP
Mb3016c|M.bovis_AF2122/97           DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAERIP
Rv2992c|M.tuberculosis_H37Rv        DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAERIP
MMAR_1719|M.marinum_M               DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALMRIGIAERVP
MUL_1957|M.ulcerans_Agy99           DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALMCIGIAERVP
MLBr_01688|M.leprae_Br4923          DPLYTLVNPCDDALMKITHVLRGEDLLSSTPRQVALYQALIRIGMAERIP
                                    :***.**** ***************:*.*****:**: *:: **:::  *

MAB_3298c|M.abscessus_ATCC_199      AFAHLPSVLGEGTKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWSIA
MSMEG_2383|M.smegmatis_MC2_155      EFAHLPSVLGEGNKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWGIA
Mflv_4229|M.gilvum_PYR-GCK          QFAHLPSVLGEGNKKLSKRDPQSNLFLHRERGFIPEGLLNYLALLGWSIA
Mvan_2133|M.vanbaalenii_PYR-1       QFAHLPSVLGEGNKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWSIA
TH_2041|M.thermoresistible__bu      EFGHLPSVLGEGNKKLSKRDPQSNLFAHRERGFIPEGLLNYLALLGWGLA
Mb3016c|M.bovis_AF2122/97           KFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIA
Rv2992c|M.tuberculosis_H37Rv        KFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIA
MMAR_1719|M.marinum_M               EFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
MUL_1957|M.ulcerans_Agy99           EFAHLPTVLGEETKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
MLBr_01688|M.leprae_Br4923          EFGHFPSVLGEGTKKLSKREPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
                                     *.*:*:**** .******:****** **:*****************.:*

MAB_3298c|M.abscessus_ATCC_199      DDHDIFSLAEMVTAFDVTDVNSNPARFDQKKADAINAEHIRLLAPEEFVT
MSMEG_2383|M.smegmatis_MC2_155      DDHDVFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLAPEDFTA
Mflv_4229|M.gilvum_PYR-GCK          DDRDIFSVQEMVAAFDVADVNSNPARFDQKKADALNAEHIRRLDEAEFVR
Mvan_2133|M.vanbaalenii_PYR-1       DDHDIFSLEEMVAAFDVADVNSSPARFDQKKADALNAEHIRLLDEAEFAR
TH_2041|M.thermoresistible__bu      DDRDVFTLDEMVAAFDVTDVNSNPARFDQKKAEALNAEHIRMLDEADFAE
Mb3016c|M.bovis_AF2122/97           DDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTV
Rv2992c|M.tuberculosis_H37Rv        DDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTV
MMAR_1719|M.marinum_M               DDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLDVADFTA
MUL_1957|M.ulcerans_Agy99           DDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLDVADFTA
MLBr_01688|M.leprae_Br4923          DDHDLFSLDEMVAAFDVVDVNSNPARFDQKKADAVNAEHIRMLDSEDFAG
                                    **:*:* : ***:****.****.*********:*:****** *   :*. 

MAB_3298c|M.abscessus_ATCC_199      RLRTYFAAHGHELGLD----ESAFAVAADLVQTRIVVLGDAWGLLKFLND
MSMEG_2383|M.smegmatis_MC2_155      RLREYFVTHGYDTTLD----DAAFAEAAALVQTRVVVLGDAWGLLKFFND
Mflv_4229|M.gilvum_PYR-GCK          RLADYFSTHGYDTGLD----DARFAEAAALVQTRIVVLGDAWDLLKFLDE
Mvan_2133|M.vanbaalenii_PYR-1       RLGAYFATHGHRTGLD----DAQFAEAARLVQTRIVVLGDAWELLKFLDD
TH_2041|M.thermoresistible__bu      RLKAYFAAHGHDTGLD----DEQFAMAARLAQTRIVVLADAWDLLKFLDD
Mb3016c|M.bovis_AF2122/97           RLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDAWELLKFFND
Rv2992c|M.tuberculosis_H37Rv        RLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDAWELLKFFND
MMAR_1719|M.marinum_M               RLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDAWALLKFLND
MUL_1957|M.ulcerans_Agy99           RLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDAWALLKFLND
MLBr_01688|M.leprae_Br4923          RLRDYFTTHGYHIALDPANYEAGFVAAAQLVQTRIVVLGDAWDLLKFLND
                                    **  :: :**:   **    :  *. ** *.***:*** *** ****:::

MAB_3298c|M.abscessus_ATCC_199      DAYAIDPGAARKELGEASLPVLDAAIGALESLEAWTTPAIEGALKSALIE
MSMEG_2383|M.smegmatis_MC2_155      DAYEIDEKSAAKELKPESAAVLDAALSALEAVGDWTTPAIEAALKTALLE
Mflv_4229|M.gilvum_PYR-GCK          SSFALDEKSAGKELKDTAVPVLTAALAALKGVGEWTTAQIEDALKVALID
Mvan_2133|M.vanbaalenii_PYR-1       ASFTLDEKSAAKELKAEAVPVLGAALEALRGVEAWDTAAIEEALKGALID
TH_2041|M.thermoresistible__bu      DSFELDEKAARKELKAEAVAVLDAALTALEALDEWRTETIEIALKAALLE
Mb3016c|M.bovis_AF2122/97           DQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIE
Rv2992c|M.tuberculosis_H37Rv        DQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIE
MMAR_1719|M.marinum_M               DRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIEAALKTALIE
MUL_1957|M.ulcerans_Agy99           DRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIEAALKTALIG
MLBr_01688|M.leprae_Br4923          DEYSIDSKAAAKELDADAGPVLDVACAVLDSLVDWTTASIEDVLKVALIE
                                      : :*  :* ***   . .** .*  .* .   * :  ** .** **: 

MAB_3298c|M.abscessus_ATCC_199      GLELKPRKAFGPLRVAVTGATVSPPLFESMELLGSGRTLTRLRNARSWEN
MSMEG_2383|M.smegmatis_MC2_155      GLELKPRKAFGPIRVAVTGAAVSPPLFESMELLGRDRSLARLRAAR----
Mflv_4229|M.gilvum_PYR-GCK          GLELKPRKAFGPVRVAVTGSSISPPLFESLELLGRDRSLERLRAGRDHAA
Mvan_2133|M.vanbaalenii_PYR-1       RLELKPRKAFGPVRVAATGSSVSPPLFESLELLGRDRSLARLQAGRDHAA
TH_2041|M.thermoresistible__bu      GLGLKPRKAFGPVRVAATGATVSPPLFESLELLGRERTLQRLRAGRDHAA
Mb3016c|M.bovis_AF2122/97           GLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVG
Rv2992c|M.tuberculosis_H37Rv        GLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVG
MMAR_1719|M.marinum_M               GMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGRLRSARDQVG
MUL_1957|M.ulcerans_Agy99           GMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGRLRSARDQVG
MLBr_01688|M.leprae_Br4923          GLGLKPRKVFGPIRVAATGALVSPPLFESLELLGRARSLQRLSAARARVT
                                     : *****.*.*:***.**: :*******:****  *:: **  .*    

MAB_3298c|M.abscessus_ATCC_199      GVGDQTDSG
MSMEG_2383|M.smegmatis_MC2_155      ---DRV---
Mflv_4229|M.gilvum_PYR-GCK          AAVTMDA--
Mvan_2133|M.vanbaalenii_PYR-1       AAAAPQG--
TH_2041|M.thermoresistible__bu      AAESTGG--
Mb3016c|M.bovis_AF2122/97           HA-------
Rv2992c|M.tuberculosis_H37Rv        HA-------
MMAR_1719|M.marinum_M               SP-------
MUL_1957|M.ulcerans_Agy99           SP-------
MLBr_01688|M.leprae_Br4923          SA-------