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TGAGRFAPSPSGDLHIGNLRTALLAWLLAHSTGRRFLMRVEDLDTRTSSAVAQRQLADLAAIGVRWELPV VWQSDRAPAYDEVIASLASRHLLYECYCSRKDIAQAPTAPHAPPGAYPGTCRDLSESERAQRRLDRAQRP PALRLRTENSPFTVQDLLHGEYTGLVDDFVVRRGDGVTAYNVAVVIDDHAQGIDQVVRGEDLLASAPRQA YLAALLGYPAPTYAHVPLVLNTAGARLAKRDGAVTLADLGAQRAFAMICDSLGYQAADATDLLRQFDAGR IPREPWIYPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0278c | - | - | 100% (291) | glutamyl-Q tRNA(Asp) synthetase |
| M. abscessus ATCC 19977 | MAB_3298c | gltX | 2e-30 | 35.69% (255) | glutamyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_1079 | - | 3e-05 | 30.91% (110) | putative molybdopterin biosynthesis protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3016c | gltX | 1e-28 | 33.79% (293) | glutamyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_1233 | - | 1e-114 | 68.97% (290) | glutamyl-Q tRNA(Asp) synthetase |
| M. tuberculosis H37Rv | Rv2992c | gltX | 1e-28 | 33.79% (293) | glutamyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_01688 | gltX | 6e-27 | 32.42% (293) | glutamyl-tRNA synthetase |
| M. marinum M | MMAR_1719 | gltX | 8e-28 | 33.45% (293) | glutamyl-tRNA synthetase GltS |
| M. avium 104 | MAV_1097 | - | 6e-05 | 33.65% (104) | putative molybdenum cofactor synthesis protein |
| M. smegmatis MC2 155 | MSMEG_6306 | gltX | 1e-115 | 69.93% (286) | glutamyl-Q tRNA(Asp) synthetase |
| M. thermoresistible (build 8) | TH_1673 | gltX | 1e-113 | 69.79% (288) | glutamyl-tRNA synthetase |
| M. ulcerans Agy99 | MUL_1957 | gltX | 9e-23 | 32.26% (279) | glutamyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_5575 | - | 1e-115 | 68.28% (290) | glutamyl-Q tRNA(Asp) synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3016c|M.bovis_AF2122/97 ---------------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYAR
Rv2992c|M.tuberculosis_H37Rv ---------------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYAR
MMAR_1719|M.marinum_M ----------------MTSSSVRVRFCPSPTGIPHVGMVRTALFNWAYAR
MUL_1957|M.ulcerans_Agy99 -------------------------------------MVRTALFNWAYAR
MLBr_01688|M.leprae_Br4923 -------MTAVTSDGTPQAAKVRVRFCPSPTGVPHVGMVRTALFNWAYAR
Mflv_1233|M.gilvum_PYR-GCK MRS--------------TRTAGAGRFAPSPSADLHIGNLRTAVLAWLFAR
Mvan_5575|M.vanbaalenii_PYR-1 MRGGYRECTLTGKVVPVTNSPGAGRFAPSPSADLHIGNLRTAVLAWLFAR
MSMEG_6306|M.smegmatis_MC2_155 ------------------MSNAAGRFAPSPSADLHIGNLRTAVLAWLFAR
TH_1673|M.thermoresistible__bu -------------MARVSSSPGAGRFAPSPSADLHIGNLRTAVLAWLFAR
MAB_0278c|M.abscessus_ATCC_199 -------------------MTGAGRFAPSPSGDLHIGNLRTALLAWLLAH
MAV_1097|M.avium_104 -------------------------------------------METGAEL
:
Mb3016c|M.bovis_AF2122/97 HTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPY
Rv2992c|M.tuberculosis_H37Rv HTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPY
MMAR_1719|M.marinum_M HTGGTFVFRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPY
MUL_1957|M.ulcerans_Agy99 HTGGTFVFRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPY
MLBr_01688|M.leprae_Br4923 HTGGTFVLRIEDTDADRDSEESYLALLDALRWLGLNWDEGPEVGGPYGPY
Mflv_1233|M.gilvum_PYR-GCK STGRRFLMRVEDLDD-RTHTDIADRQLADLAALGITWDGD--------AT
Mvan_5575|M.vanbaalenii_PYR-1 STGRRFLMRVEDLDD-RTHTDIADRQLADLAALGVTWDGP--------AI
MSMEG_6306|M.smegmatis_MC2_155 STGRRFLVRVEDLDD-RTFPEIGRRQVADLAAVGLTWDEP--------VE
TH_1673|M.thermoresistible__bu STGRRFLIRVEDLDE-RTDAGTAARQLRDLEAIGLTWDGP--------VV
MAB_0278c|M.abscessus_ATCC_199 STGRRFLMRVEDLDT-RTSSAVAQRQLADLAAIGVRWELP--------VV
MAV_1097|M.avium_104 VVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGV--------VA
.* ::. ::* * *. :
Mb3016c|M.bovis_AF2122/97 RQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNF
Rv2992c|M.tuberculosis_H37Rv RQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNF
MMAR_1719|M.marinum_M RQSQRTEIYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNF
MUL_1957|M.ulcerans_Agy99 RQSQRTEIYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNF
MLBr_01688|M.leprae_Br4923 RQSQRTDIYREVVAKLLATGEAYYAFSTPEEVENRHLAAGRNPKLGYDNF
Mflv_1233|M.gilvum_PYR-GCK RQTDHPERYDAVVDGLAGSGLLFECYCTRRDIAQAPRAP-HAPEGAYPGT
Mvan_5575|M.vanbaalenii_PYR-1 WQSEHPERYDAVVDTLDERGLLFECYCTRRDIAQAPRAP-HAPEGAYPGT
MSMEG_6306|M.smegmatis_MC2_155 WQTTHEDRYDAVIDQLAGEGLLYECYCSRKDIAQAPRAP-HAPQGAYPGT
TH_1673|M.thermoresistible__bu WQSRRRPIYQAVVDKLVADDLVYECYCSRKDIAQAPRAP-HAPQGAYPGT
MAB_0278c|M.abscessus_ATCC_199 WQSDRAPAYDEVIASLASRHLLYECYCSRKDIAQAPTAP-HAPPGAYPGT
MAV_1097|M.avium_104 VAADEVEIRNALNTAVIGG----------VDLVVSVGGTGVTPRDVTPEA
: . : : :: .. *
Mb3016c|M.bovis_AF2122/97 DRHLTDAQRAAYLAEGR--QPVVRLRMPDDDLAWNDLVRGPVTFAAGSVP
Rv2992c|M.tuberculosis_H37Rv DRHLTDAQRAAYLAEGR--QPVVRLRMPDDDLAWNDLVRGPVTFAAGSVP
MMAR_1719|M.marinum_M DRQLTDSQRAAYLAEGR--KPVVRLRMPDTDLAWHDLVRGPTTFAAGSVP
MUL_1957|M.ulcerans_Agy99 DRQLTDSQRAAYLAEGR--KPVVRLRMPDTDLAWHDLVRGPTTFAAGSVP
MLBr_01688|M.leprae_Br4923 DRDLTDAQFSAYLAEGR--KPVVRLRMPDEDISWDDLVRGTTTFAVGTVP
Mflv_1233|M.gilvum_PYR-GCK CRDLTDAERDQRRDETG-RPPALRLRTDTTSHTVHDVLHG---DYTGLVD
Mvan_5575|M.vanbaalenii_PYR-1 CRNLDNADRERRRRETG-RPPALRLRTDTTEYTVHDVLHG---DYTGLVD
MSMEG_6306|M.smegmatis_MC2_155 CRDLTDDERAARRRETG-RPPAMRLRTDTFVYTVNDVLHG---PYTGIVD
TH_1673|M.thermoresistible__bu CRDLTRSRRERRRRETG-RPPALRLRTDVTHHAVTDLLHG---SYHGHVD
MAB_0278c|M.abscessus_ATCC_199 CRDLSESERAQRRLDRAQRPPALRLRTENSPFTVQDLLHG---EYTGLVD
MAV_1097|M.avium_104 TREILDR-------------------------------------------
*.:
Mb3016c|M.bovis_AF2122/97 DFALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALI
Rv2992c|M.tuberculosis_H37Rv DFALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALI
MMAR_1719|M.marinum_M DFALTRATGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALM
MUL_1957|M.ulcerans_Agy99 DFALTRATGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALM
MLBr_01688|M.leprae_Br4923 DYVLTRASGDPLYTLVNPCDDALMKITHVLRGEDLLSSTPRQVALYQALI
Mflv_1233|M.gilvum_PYR-GCK DFVVRRGDGVPAYNLAVVVDDAASGIDQVVRGDDLLSSSPRQAYLARLLG
Mvan_5575|M.vanbaalenii_PYR-1 DFVVRRGDGVPAYNLAVVVDDAATGVDQVVRGDDLLSSSPRQAYLARLLG
MSMEG_6306|M.smegmatis_MC2_155 DFVVRRGDGVPAYNLAVVVDDAASGIDQVVRGDDLLPSSPRQAYLARLLG
TH_1673|M.thermoresistible__bu DFVVLRGDGVPAYNLAVVVDDAAQGIDQVVRGDDLLSSAPRQAYLARLLG
MAB_0278c|M.abscessus_ATCC_199 DFVVRRGDGVTAYNVAVVIDDHAQGIDQVVRGEDLLASAPRQAYLAALLG
MAV_1097|M.avium_104 ---------------------EILGIAEAIRGSGLSAGIIDAGLSRGLAG
: ..:**..* ..
Mb3016c|M.bovis_AF2122/97 RIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNY
Rv2992c|M.tuberculosis_H37Rv RIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNY
MMAR_1719|M.marinum_M RIGIAERVPEFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNY
MUL_1957|M.ulcerans_Agy99 CIGIAERVPEFAHLPTVLGEETKKLSKRDPQSNLFAHRDRGFIPEGLLNY
MLBr_01688|M.leprae_Br4923 RIGMAERIPEFGHFPSVLGEGTKKLSKREPQSNLFAHRDRGFIPEGLLNY
Mflv_1233|M.gilvum_PYR-GCK -----HPEPVYAHVPLVLNADGARLAKRDGAVTLAEIG----LSKALAQI
Mvan_5575|M.vanbaalenii_PYR-1 -----HPEPVYAHVPLVLNGDGARLAKRDGAVTLAEIG----VAQALRQI
MSMEG_6306|M.smegmatis_MC2_155 -----HPEPTYAHVPLVLNEDGARLAKRDGAVTLAEIG----VERAFAQI
TH_1673|M.thermoresistible__bu -----HRPPQYAHVPLVLNTAGKRLAKRDGAVTLPELG----VRRAFELI
MAB_0278c|M.abscessus_ATCC_199 -----YPAPTYAHVPLVLNTAGARLAKRDGAVTLADLG----AQRAFAMI
MAV_1097|M.avium_104 ----------VSGSTLVVNLAGSRYAVRDGMATLNPLA------------
. . *:. : : *: .*
Mb3016c|M.bovis_AF2122/97 LALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIR
Rv2992c|M.tuberculosis_H37Rv LALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIR
MMAR_1719|M.marinum_M LALLGWAIADDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIR
MUL_1957|M.ulcerans_Agy99 LALLGWAIADDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIR
MLBr_01688|M.leprae_Br4923 LALLGWAIADDHDLFSLDEMVAAFDVVDVNSNPARFDQKKADAVNAEHIR
Mflv_1233|M.gilvum_PYR-GCK ADSLGYAARS------VEAMLDEFDPQRLPRQAWVYQPG-----------
Mvan_5575|M.vanbaalenii_PYR-1 ADSLGYEAHA------VGGMLDEFDPRRLPRVPWVYRPG-----------
MSMEG_6306|M.smegmatis_MC2_155 TESLGRPATT------MDELLARFDPDQLPRHPWIYRPV-----------
TH_1673|M.thermoresistible__bu SASLGWPASN------LAELLDQFDPAALPRSPWIWPATP----------
MAB_0278c|M.abscessus_ATCC_199 CDSLGYQAAD------ATDLLRQFDAGRIPREPWIYPG------------
MAV_1097|M.avium_104 -----------------AQIIGQLSSLEI---------------------
:: :. :
Mb3016c|M.bovis_AF2122/97 MLDVGDFTVRLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDA
Rv2992c|M.tuberculosis_H37Rv MLDVGDFTVRLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDA
MMAR_1719|M.marinum_M MLDVADFTARLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDA
MUL_1957|M.ulcerans_Agy99 MLDVADFTARLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDA
MLBr_01688|M.leprae_Br4923 MLDSEDFAGRLRDYFTTHGYHIALDPANYEAGFVAAAQLVQTRIVVLGDA
Mflv_1233|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5575|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6306|M.smegmatis_MC2_155 --------------------------------------------------
TH_1673|M.thermoresistible__bu --------------------------------------------------
MAB_0278c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_1097|M.avium_104 --------------------------------------------------
Mb3016c|M.bovis_AF2122/97 WELLKFFNDDQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIE
Rv2992c|M.tuberculosis_H37Rv WELLKFFNDDQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIE
MMAR_1719|M.marinum_M WALLKFLNDDRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIE
MUL_1957|M.ulcerans_Agy99 WALLKFLNDDRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIE
MLBr_01688|M.leprae_Br4923 WDLLKFLNDDEYSIDSKAAAKELDADAGPVLDVACAVLDSLVDWTTASIE
Mflv_1233|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5575|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6306|M.smegmatis_MC2_155 --------------------------------------------------
TH_1673|M.thermoresistible__bu --------------------------------------------------
MAB_0278c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_1097|M.avium_104 --------------------------------------------------
Mb3016c|M.bovis_AF2122/97 AALKDALIEGLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQR
Rv2992c|M.tuberculosis_H37Rv AALKDALIEGLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQR
MMAR_1719|M.marinum_M AALKTALIEGMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGR
MUL_1957|M.ulcerans_Agy99 AALKTALIGGMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGR
MLBr_01688|M.leprae_Br4923 DVLKVALIEGLGLKPRKVFGPIRVAATGALVSPPLFESLELLGRARSLQR
Mflv_1233|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5575|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6306|M.smegmatis_MC2_155 --------------------------------------------------
TH_1673|M.thermoresistible__bu --------------------------------------------------
MAB_0278c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_1097|M.avium_104 --------------------------------------------------
Mb3016c|M.bovis_AF2122/97 LRAARQLVGHA
Rv2992c|M.tuberculosis_H37Rv LRAARQLVGHA
MMAR_1719|M.marinum_M LRSARDQVGSP
MUL_1957|M.ulcerans_Agy99 LRSARDQVGSP
MLBr_01688|M.leprae_Br4923 LSAARARVTSA
Mflv_1233|M.gilvum_PYR-GCK -----------
Mvan_5575|M.vanbaalenii_PYR-1 -----------
MSMEG_6306|M.smegmatis_MC2_155 -----------
TH_1673|M.thermoresistible__bu -----------
MAB_0278c|M.abscessus_ATCC_199 -----------
MAV_1097|M.avium_104 -----------