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VTTSDVVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGTFVFRIEDTDSARDSEDSYLALLDALRWLGM DWDEGPEIGGPYGPYRQSQRLDIYTDVIERLLAAGEAYEAFSTAEEVEARHIAAGRNPKLGYDNYDRDLT EEQRAAFRAEGRRPVVRLRMPDTDLTWVDLVRGETTFPAGSVPDFALTRGNGEPLYPLVNPVDDALMKIT HVLRGEDLLPSTPRQLALYGALIRIGVADTTPQFAHLPSVLGEGNKKLSKRDPQSNLFLHRDRGFIPEGL LNYLALLGWSIADDHDIFSLEEMVAAFDVADVNSSPARFDQKKADALNAEHIRLLDEAEFARRLGAYFAT HGHRTGLDDAQFAEAARLVQTRIVVLGDAWELLKFLDDASFTLDEKSAAKELKAEAVPVLGAALEALRGV EAWDTAAIEEALKGALIDRLELKPRKAFGPVRVAATGSSVSPPLFESLELLGRDRSLARLQAGRDHAAAA AAPQG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2133 | gltX | - | 100% (495) | glutamyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_5575 | - | 2e-32 | 37.01% (254) | glutamyl-Q tRNA(Asp) synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3016c | gltX | 0.0 | 78.51% (484) | glutamyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_4229 | gltX | 0.0 | 88.22% (484) | glutamyl-tRNA synthetase |
| M. tuberculosis H37Rv | Rv2992c | gltX | 0.0 | 78.51% (484) | glutamyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_01688 | gltX | 0.0 | 73.98% (488) | glutamyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_3298c | gltX | 0.0 | 79.71% (478) | glutamyl-tRNA synthetase |
| M. marinum M | MMAR_1719 | gltX | 0.0 | 78.23% (487) | glutamyl-tRNA synthetase GltS |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2383 | gltX | 0.0 | 79.71% (483) | glutamyl-tRNA synthetase |
| M. thermoresistible (build 8) | TH_2041 | gltS | 0.0 | 82.11% (492) | PROBABLE GLUTAMYL-TRNA SYNTHETASE GLTS (GLUTAMATE--TRNA |
| M. ulcerans Agy99 | MUL_1957 | gltX | 0.0 | 77.52% (467) | glutamyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2133|M.vanbaalenii_PYR-1 --------MTTSDVVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGTFV
Mflv_4229|M.gilvum_PYR-GCK ------------MKVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGDFV
TH_2041|M.thermoresistible__bu ----MTEPTDGSTKVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGTFV
MAB_3298c|M.abscessus_ATCC_199 ---------MSNTKIRVRFCPSPTGTPHVGLIRTALFNWAYARHCGGDFV
MSMEG_2383|M.smegmatis_MC2_155 ---------MTTKKVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGDFV
Mb3016c|M.bovis_AF2122/97 --------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFV
Rv2992c|M.tuberculosis_H37Rv --------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFV
MMAR_1719|M.marinum_M ---------MTSSSVRVRFCPSPTGIPHVGMVRTALFNWAYARHTGGTFV
MUL_1957|M.ulcerans_Agy99 ------------------------------MVRTALFNWAYARHTGGTFV
MLBr_01688|M.leprae_Br4923 MTAVTSDGTPQAAKVRVRFCPSPTGVPHVGMVRTALFNWAYARHTGGTFV
::************ ** **
Mvan_2133|M.vanbaalenii_PYR-1 FRIEDTDSARDSEDSYLALLDALRWLGMDWDEGPEIGGPYGPYRQSQRLD
Mflv_4229|M.gilvum_PYR-GCK FRIEDTDAQRDSEESYLALLDALRWLGMDWDEGPEVGGPYAPYRQSQRRD
TH_2041|M.thermoresistible__bu FRIEDTDSARDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSERLH
MAB_3298c|M.abscessus_ATCC_199 FRIEDTDAGRDSEESYLAILDALRWLGLDWDEGPEVGGPYEPYRQSQRKE
MSMEG_2383|M.smegmatis_MC2_155 FRIEDTDAARDSDESYAAILDALRWLGMDWDEGPEVGGPYEPYRQSQRRE
Mb3016c|M.bovis_AF2122/97 FRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAE
Rv2992c|M.tuberculosis_H37Rv FRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAE
MMAR_1719|M.marinum_M FRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPYRQSQRTE
MUL_1957|M.ulcerans_Agy99 FRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPYRQSQRTE
MLBr_01688|M.leprae_Br4923 LRIEDTDADRDSEESYLALLDALRWLGLNWDEGPEVGGPYGPYRQSQRTD
:******: ***::** *:********::******:.*** *****:* .
Mvan_2133|M.vanbaalenii_PYR-1 IYTDVIERLLAAGEAYEAFSTAEEVEARHIAAGRNPKLGYDNYDRDLTEE
Mflv_4229|M.gilvum_PYR-GCK LYLDVIRRLLAAGEAYEAFSTAEEVEARHLAAGRNPKLGYDNFDRDLTEE
TH_2041|M.thermoresistible__bu IYRDVIERLLESGAAYESFSTPEEVEARHRAAGRNPKLGYDNFDRDLTEE
MAB_3298c|M.abscessus_ATCC_199 LHREVVRKLLEAGEAYEAFSTAEEVEARHLAAGRNPKLGYDNYDRDLTEE
MSMEG_2383|M.smegmatis_MC2_155 IYRDVVARLLEAGEVYEAYSTPEEVEARHLAAGRNPKLGYDNYDRDLTDA
Mb3016c|M.bovis_AF2122/97 IYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDA
Rv2992c|M.tuberculosis_H37Rv IYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDA
MMAR_1719|M.marinum_M IYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNFDRQLTDS
MUL_1957|M.ulcerans_Agy99 IYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNFDRQLTDS
MLBr_01688|M.leprae_Br4923 IYREVVAKLLATGEAYYAFSTPEEVENRHLAAGRNPKLGYDNFDRDLTDA
:: :*: :** :* .* ::**.**** ** ************:**.**:
Mvan_2133|M.vanbaalenii_PYR-1 QRAAFRAEGRRPVVRLRMPDTDLTWVDLVRGETTFPAGSVPDFALTRGNG
Mflv_4229|M.gilvum_PYR-GCK QRAAFRAEGRQPVVRLRMPDADMTWVDLVRGETTFPVGSVPDFALTRGSG
TH_2041|M.thermoresistible__bu QRRAYRAEGRRPVIRLKMPDRDIGWRDLVRGETTFPAGTLADFALTRSNG
MAB_3298c|M.abscessus_ATCC_199 QRAAFRAEGRDPVVRLRMPDHDITWNDLVRGETTFAAGVVPDFALTRGNG
MSMEG_2383|M.smegmatis_MC2_155 QRKAFADEGRRPVLRLRMPDEDLSWNDLVRGPTTFAAGSVPDFAITRSNG
Mb3016c|M.bovis_AF2122/97 QRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASG
Rv2992c|M.tuberculosis_H37Rv QRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASG
MMAR_1719|M.marinum_M QRAAYLAEGRKPVVRLRMPDTDLAWHDLVRGPTTFAAGSVPDFALTRATG
MUL_1957|M.ulcerans_Agy99 QRAAYLAEGRKPVVRLRMPDTDLAWHDLVRGPTTFAAGSVPDFALTRATG
MLBr_01688|M.leprae_Br4923 QFSAYLAEGRKPVVRLRMPDEDISWDDLVRGTTTFAVGTVPDYVLTRASG
* *: *** **:**:*** *: * ***** .**..* :.*:.:**..*
Mvan_2133|M.vanbaalenii_PYR-1 EPLYPLVNPVDDALMKITHVLRGEDLLPSTPRQLALYGALIRIGVADTTP
Mflv_4229|M.gilvum_PYR-GCK DPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQLALYAALIRIGVTDMTP
TH_2041|M.thermoresistible__bu EPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQIALYEALMAIGVADTVP
MAB_3298c|M.abscessus_ATCC_199 DPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQIALYEAMIRIGVTDSIP
MSMEG_2383|M.smegmatis_MC2_155 DPLYTLVNPVDDALMKITHVLRGEDILPSTPRQIALYRALMRIGVAEFVP
Mb3016c|M.bovis_AF2122/97 DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAERIP
Rv2992c|M.tuberculosis_H37Rv DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAERIP
MMAR_1719|M.marinum_M DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALMRIGIAERVP
MUL_1957|M.ulcerans_Agy99 DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALMCIGIAERVP
MLBr_01688|M.leprae_Br4923 DPLYTLVNPCDDALMKITHVLRGEDLLSSTPRQVALYQALIRIGMAERIP
:***.**** ***************:*.*****:**: *:: **::: *
Mvan_2133|M.vanbaalenii_PYR-1 QFAHLPSVLGEGNKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWSIA
Mflv_4229|M.gilvum_PYR-GCK QFAHLPSVLGEGNKKLSKRDPQSNLFLHRERGFIPEGLLNYLALLGWSIA
TH_2041|M.thermoresistible__bu EFGHLPSVLGEGNKKLSKRDPQSNLFAHRERGFIPEGLLNYLALLGWGLA
MAB_3298c|M.abscessus_ATCC_199 AFAHLPSVLGEGTKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWSIA
MSMEG_2383|M.smegmatis_MC2_155 EFAHLPSVLGEGNKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWGIA
Mb3016c|M.bovis_AF2122/97 KFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIA
Rv2992c|M.tuberculosis_H37Rv KFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIA
MMAR_1719|M.marinum_M EFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
MUL_1957|M.ulcerans_Agy99 EFAHLPTVLGEETKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
MLBr_01688|M.leprae_Br4923 EFGHFPSVLGEGTKKLSKREPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
*.*:*:**** .******:****** **:*****************.:*
Mvan_2133|M.vanbaalenii_PYR-1 DDHDIFSLEEMVAAFDVADVNSSPARFDQKKADALNAEHIRLLDEAEFAR
Mflv_4229|M.gilvum_PYR-GCK DDRDIFSVQEMVAAFDVADVNSNPARFDQKKADALNAEHIRRLDEAEFVR
TH_2041|M.thermoresistible__bu DDRDVFTLDEMVAAFDVTDVNSNPARFDQKKAEALNAEHIRMLDEADFAE
MAB_3298c|M.abscessus_ATCC_199 DDHDIFSLAEMVTAFDVTDVNSNPARFDQKKADAINAEHIRLLAPEEFVT
MSMEG_2383|M.smegmatis_MC2_155 DDHDVFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLAPEDFTA
Mb3016c|M.bovis_AF2122/97 DDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTV
Rv2992c|M.tuberculosis_H37Rv DDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTV
MMAR_1719|M.marinum_M DDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLDVADFTA
MUL_1957|M.ulcerans_Agy99 DDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLDVADFTA
MLBr_01688|M.leprae_Br4923 DDHDLFSLDEMVAAFDVVDVNSNPARFDQKKADAVNAEHIRMLDSEDFAG
**:*:* : ***:****.****.*********:*:****** * :*.
Mvan_2133|M.vanbaalenii_PYR-1 RLGAYFATHGHRTGLD----DAQFAEAARLVQTRIVVLGDAWELLKFLDD
Mflv_4229|M.gilvum_PYR-GCK RLADYFSTHGYDTGLD----DARFAEAAALVQTRIVVLGDAWDLLKFLDE
TH_2041|M.thermoresistible__bu RLKAYFAAHGHDTGLD----DEQFAMAARLAQTRIVVLADAWDLLKFLDD
MAB_3298c|M.abscessus_ATCC_199 RLRTYFAAHGHELGLD----ESAFAVAADLVQTRIVVLGDAWGLLKFLND
MSMEG_2383|M.smegmatis_MC2_155 RLREYFVTHGYDTTLD----DAAFAEAAALVQTRVVVLGDAWGLLKFFND
Mb3016c|M.bovis_AF2122/97 RLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDAWELLKFFND
Rv2992c|M.tuberculosis_H37Rv RLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDAWELLKFFND
MMAR_1719|M.marinum_M RLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDAWALLKFLND
MUL_1957|M.ulcerans_Agy99 RLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDAWALLKFLND
MLBr_01688|M.leprae_Br4923 RLRDYFTTHGYHIALDPANYEAGFVAAAQLVQTRIVVLGDAWDLLKFLND
** :: :**: ** : *. ** *.***:*** *** ****:::
Mvan_2133|M.vanbaalenii_PYR-1 ASFTLDEKSAAKELKAEAVPVLGAALEALRGVEAWDTAAIEEALKGALID
Mflv_4229|M.gilvum_PYR-GCK SSFALDEKSAGKELKDTAVPVLTAALAALKGVGEWTTAQIEDALKVALID
TH_2041|M.thermoresistible__bu DSFELDEKAARKELKAEAVAVLDAALTALEALDEWRTETIEIALKAALLE
MAB_3298c|M.abscessus_ATCC_199 DAYAIDPGAARKELGEASLPVLDAAIGALESLEAWTTPAIEGALKSALIE
MSMEG_2383|M.smegmatis_MC2_155 DAYEIDEKSAAKELKPESAAVLDAALSALEAVGDWTTPAIEAALKTALLE
Mb3016c|M.bovis_AF2122/97 DQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIE
Rv2992c|M.tuberculosis_H37Rv DQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIE
MMAR_1719|M.marinum_M DRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIEAALKTALIE
MUL_1957|M.ulcerans_Agy99 DRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIEAALKTALIG
MLBr_01688|M.leprae_Br4923 DEYSIDSKAAAKELDADAGPVLDVACAVLDSLVDWTTASIEDVLKVALIE
: :* :* *** . .** .* .* . * : ** .** **:
Mvan_2133|M.vanbaalenii_PYR-1 RLELKPRKAFGPVRVAATGSSVSPPLFESLELLGRDRSLARLQAGRDHAA
Mflv_4229|M.gilvum_PYR-GCK GLELKPRKAFGPVRVAVTGSSISPPLFESLELLGRDRSLERLRAGRDHAA
TH_2041|M.thermoresistible__bu GLGLKPRKAFGPVRVAATGATVSPPLFESLELLGRERTLQRLRAGRDHAA
MAB_3298c|M.abscessus_ATCC_199 GLELKPRKAFGPLRVAVTGATVSPPLFESMELLGSGRTLTRLRNARSWEN
MSMEG_2383|M.smegmatis_MC2_155 GLELKPRKAFGPIRVAVTGAAVSPPLFESMELLGRDRSLARLRAAR----
Mb3016c|M.bovis_AF2122/97 GLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVG
Rv2992c|M.tuberculosis_H37Rv GLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVG
MMAR_1719|M.marinum_M GMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGRLRSARDQVG
MUL_1957|M.ulcerans_Agy99 GMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGRLRSARDQVG
MLBr_01688|M.leprae_Br4923 GLGLKPRKVFGPIRVAATGALVSPPLFESLELLGRARSLQRLSAARARVT
: *****.*.*:***.**: :*******:**** *:: ** .*
Mvan_2133|M.vanbaalenii_PYR-1 AAAAPQG--
Mflv_4229|M.gilvum_PYR-GCK AAVTMDA--
TH_2041|M.thermoresistible__bu AAESTGG--
MAB_3298c|M.abscessus_ATCC_199 GVGDQTDSG
MSMEG_2383|M.smegmatis_MC2_155 ---DRV---
Mb3016c|M.bovis_AF2122/97 HA-------
Rv2992c|M.tuberculosis_H37Rv HA-------
MMAR_1719|M.marinum_M SP-------
MUL_1957|M.ulcerans_Agy99 SP-------
MLBr_01688|M.leprae_Br4923 SA-------