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TGVGIFGAFLGGLASLLSPCSALLLPSFFAYAFDRVQRLVQRTTAFWVGLCVVLVPLGAGVSALGGALTR YRGEVTMIGGVVIIGMGLMTVLGRGFALSSAQRLFARIRISTTMSVIALGALYGLAGFCAGPLLGGVLTV SAMGGDPVLGGTLMAVYALGMAAPLFVLALLWKRFDLSRRGWLRGKSVKWGPVHTHSTSLVSGVILVVIG TVFLVTDGTANLGGVLGVDEQFDLQVWLRVMGTSAADPIVLLGVVGASLAWRGHRLWRRRSESDESVTVS GGGGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5557 | - | - | 100% (286) | cytochrome c biogenesis protein, transmembrane region |
| M. vanbaalenii PYR-1 | Mvan_3693 | - | 2e-12 | 32.05% (234) | cytochrome c biogenesis protein, transmembrane region |
| M. vanbaalenii PYR-1 | Mvan_0867 | - | 3e-11 | 28.14% (231) | cytochrome c biogenesis protein, transmembrane region |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0540 | ccdA | 8e-13 | 27.97% (236) | cytochrome C-type biogenesis protein CcdA |
| M. gilvum PYR-GCK | Mflv_2825 | - | 8e-13 | 30.30% (231) | cytochrome c biogenesis protein, transmembrane region |
| M. tuberculosis H37Rv | Rv0527 | ccdA | 8e-13 | 27.97% (236) | cytochrome C-type biogenesis protein CcdA |
| M. leprae Br4923 | MLBr_02411 | - | 5e-10 | 26.64% (229) | putative cytochrome C-type biogenesis protein |
| M. abscessus ATCC 19977 | MAB_4286 | - | 3e-74 | 50.18% (271) | putative integral membrane cytochrome c biogenesis protein |
| M. marinum M | MMAR_0873 | ccsA | 2e-11 | 30.70% (228) | cytochrome C-type biogenesis protein, CcsA |
| M. avium 104 | MAV_4618 | - | 2e-12 | 30.70% (228) | cytochrome C biogenesis protein transmembrane region |
| M. smegmatis MC2 155 | MSMEG_0972 | - | 8e-14 | 30.43% (230) | cytochrome C biogenesis protein transmembrane region |
| M. thermoresistible (build 8) | TH_2250 | ccsA | 1e-11 | 29.32% (249) | POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCDA |
| M. ulcerans Agy99 | MUL_0626 | ccsA | 4e-12 | 31.14% (228) | cytochrome C-type biogenesis protein, CcsA |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0873|M.marinum_M MTGFAEVAAAGPLLVALGLCVLAGLVSFASPCVVPLVPGYLSYLAAVVGV
MUL_0626|M.ulcerans_Agy99 MTGFAEVAAAGPLLVALGLCVLAGLVSFASPCVVPLVPGYLSYLAAVVGV
MAV_4618|M.avium_104 MTGLTQIAAAGPLLAALGVCLLAGLVSFASPCVVPLVPGYLSYLAALVGV
Mb0540|M.bovis_AF2122/97 MTGFTEIAAVGPLLVAVGVCLLAGLVSFASPCVVPLVPGYLSYLAAVVGV
Rv0527|M.tuberculosis_H37Rv MTGFTEIAAVGPLLVAVGVCLLAGLVSFASPCVVPLVPGYLSYLAAVVGV
MLBr_02411|M.leprae_Br4923 MTGFTEIAAAGPLLVALGVCMLAGLVSFVSPCVVPLVPGYLSYLAAVVGV
MSMEG_0972|M.smegmatis_MC2_155 MTGFAEIAAAGPVLLALGVSVLAGLVSFASPCVVPLVPGYLSYLAAVVGV
TH_2250|M.thermoresistible__bu MTGFAELAAAGPVLVAVAISILAGLVSFASPCVVPLVPGYLSYLAAVVGV
Mflv_2825|M.gilvum_PYR-GCK MDGVTAIATSGHVLLAVFVSALAGLVSFASPCVVPLVPGYLSYLAAVVGV
Mvan_5557|M.vanbaalenii_PYR-1 ---MTGVGIFG--------AFLGGLASLLSPCSALLLPSFFAYAFDRVQR
MAB_4286|M.abscessus_ATCC_1997 ---MIDVGVLG--------ALLGGVLTLVSPCSALLLPSFFAYSFDRTGL
. :. * . *.*: :: *** . *:*.:::* .
MMAR_0873|M.marinum_M DGSG-DGRAAGVG---------VKAPAGVRWRVAGSALLFVAGFTTVFVL
MUL_0626|M.ulcerans_Agy99 DGSG-DGRAAGVG---------VKAPAGVRWRVAGSALLFVAGFTTVFVL
MAV_4618|M.avium_104 E----EQPQAGA----------VQAPPGARWRVAGSAALFVAGFTAVFVL
Mb0540|M.bovis_AF2122/97 D----EQLPAGV----------VKPPVAARWRVAGSAALFVAGFTTVFVL
Rv0527|M.tuberculosis_H37Rv D----EQLPAGV----------VKPPVAARWRVAGSAALFVAGFTTVFVL
MLBr_02411|M.leprae_Br4923 SHEE-TQPGAGV----------IKTPPAARWRVAGSAVLFVAGFTTVFVL
MSMEG_0972|M.smegmatis_MC2_155 DDD--PVRTGGER----------VALRSARLRVAGAAALFVAGFTVVFLL
TH_2250|M.thermoresistible__bu PKEAAPVVTGGPRRDPPADSGAGMSPRSARLRVTGAAALFVAGFTVVFLL
Mflv_2825|M.gilvum_PYR-GCK DD---DQARAQP-------------LGRARLRVAGAAGLFVVGFTAVFLM
Mvan_5557|M.vanbaalenii_PYR-1 LVQR--------------------------------TTAFWVGLCVVLVP
MAB_4286|M.abscessus_ATCC_1997 LLRS--------------------------------TGLFYLGMLTVLAP
: * *: .*:
MMAR_0873|M.marinum_M GTVAVLGMTTTLISNQLVLQRAGGVLTIIMGLVFVG-LIPALQRQARFSP
MUL_0626|M.ulcerans_Agy99 GTVAVLGMTTTLISNQLVLQRAGGVLTIIMGLVFVG-LIPALQRQARFSP
MAV_4618|M.avium_104 GTVAVLGMTTTLITNQLLLQRAGGVLTIVMGLVFVG-LIPALQRQARFSP
Mb0540|M.bovis_AF2122/97 GTVAVLGMTTTLITNQLLLQRVGGVLIVVMGLVFVG-FIGALQRQARFTP
Rv0527|M.tuberculosis_H37Rv GTVAVLGMTTTLITNQLLLQRVGGVLIVVMGLVFVG-FIGALQRQARFTP
MLBr_02411|M.leprae_Br4923 DTVAVLGMTTVLTTHQVLLQRVGGVLTIVMGLVFVG-LLPALQRQVQFSL
MSMEG_0972|M.smegmatis_MC2_155 GAVAVLGMTTTLIANQLLLQRIGGVVTIVMGLVFVG-FIPALQRQARFTP
TH_2250|M.thermoresistible__bu GTVAVLGMTTTLITNQVLLQRIGGVITIVMGLVFIG-FIPALQRQARFAP
Mflv_2825|M.gilvum_PYR-GCK GTVAILGLTTTIITNGVLLQRIGGVVTIVMGLVFMG-FFPALQRDARFTP
Mvan_5557|M.vanbaalenii_PYR-1 LGAGVSALGGALTRYRGEVTMIGGVVIIGMGLMTVLGRGFALSSAQRLFA
MAB_4286|M.abscessus_ATCC_1997 LGAGVGAIGALLTEYRSQVTTTGGLLMTTLGVAIIAGIGFRVGPAARLSA
..: .: : : **:: :*: : : ::
MMAR_0873|M.marinum_M RQ-VTTVAGAPLLGAVFALGWTPCLGPTLTGVITVASATDGASVARGIVL
MUL_0626|M.ulcerans_Agy99 RQ-VTTVAGAPLLGAVFALGWTPCLGPTLTGVITVASATNGASVARGIVL
MAV_4618|M.avium_104 RQ-LTTVAGAPLLGAVFALGWTPCLGPTLAGVITVASATDGASVARGIVL
Mb0540|M.bovis_AF2122/97 RQ-LTSVAGAPVLGAVFALGWTPCLGPTLTGVITVASATEGASVARGIVL
Rv0527|M.tuberculosis_H37Rv RQ-LTSVAGAPVLGAVFALGWTPCLGPTLTGVITVASATEGASVARGIVL
MLBr_02411|M.leprae_Br4923 RQ-LTTVAGAPVLGTVFALGWTPCLGPTLSGVITVAAATDGVNVTRGILL
MSMEG_0972|M.smegmatis_MC2_155 RQ-LSTVAGAPLLGAVFALGWTPCLGPTLTGVIAVASATDGATVARGVVL
TH_2250|M.thermoresistible__bu RQ-WSTVAGAPLLGAVFALGWTPCLGPTLTGVITVASATDGASVARGVVL
Mflv_2825|M.gilvum_PYR-GCK TS-LSTLWGAPLLGAVFGLGWTPCLGPTLTGVIAVASATEGPNVVRGIVL
Mvan_5557|M.vanbaalenii_PYR-1 RIRISTTMSVIALGALYGLAG-FCAGPLLGGVLTVSAMGGDP--VLGGTL
MAB_4286|M.abscessus_ATCC_1997 RLDLSSGLSVLLLGTVYALAG-FCSGPILGSVLTVAAIGSSP--IYGALL
:: .. **:::.*. * ** * .*::*:: . * *
MMAR_0873|M.marinum_M VIAYCLGLGIPFVLLAFGS-AGAVAGLGWLRR--------HTRAIQIFGG
MUL_0626|M.ulcerans_Agy99 VIAYCLGLGIPFVLLAFGS-AGAVAGLGWLRR--------HTRAIQIFGG
MAV_4618|M.avium_104 VIAYCLGLGIPFVLLAFGS-AGAVAGLGWLRR--------HTRAIQIFGG
Mb0540|M.bovis_AF2122/97 VIAYCLGLGIPFVLLAFGS-AWAVAGLGWLRR--------HTRAIQIFGG
Rv0527|M.tuberculosis_H37Rv VIAYCLGLGIPFVLLAFGS-AWAVAGLGWLRR--------HTRAIQIFGG
MLBr_02411|M.leprae_Br4923 VIAYCMGLGIPFVLLASGS-AQAVAGLRWLRQ--------YGRAIQVFGG
MSMEG_0972|M.smegmatis_MC2_155 VLAYCLGLGIPFVLLALGS-ARAVQGLGWLRR--------HTRTIQIFGG
TH_2250|M.thermoresistible__bu VIAYCLGLGIPFILLAFGS-ARAVQGLGWLRR--------NTRTIQIFGG
Mflv_2825|M.gilvum_PYR-GCK VVAYCVGLGAPFVLFALAS-GRAMRALGWLRR--------NARRIQVFGG
Mvan_5557|M.vanbaalenii_PYR-1 MAVYALGMAAPLFVLALLWKRFDLSRRGWLRGKSVKWGPVHTHSTSLVSG
MAB_4286|M.abscessus_ATCC_1997 MSLYSLGMAAPLFVLAFAWGKLGLSQRRWIRGRELRIGRFRTHSTNLVSG
: *.:*:. *:.::* : *:* : .:..*
MMAR_0873|M.marinum_M VLLIAVGLALVTGVWNDVVSWLR---DAFVSDVRLPI-------------
MUL_0626|M.ulcerans_Agy99 VLLIVVGLALVTGVWNDVVSWLR---DAFVSDVRLPI-------------
MAV_4618|M.avium_104 VLLITVGALLVTGLWNDFVSWLR---DAFVSDVRLPI-------------
Mb0540|M.bovis_AF2122/97 ALLIAVGAALVTGVWNDVVSWLR---DAFVSDVRLPI-------------
Rv0527|M.tuberculosis_H37Rv ALLIAVGAALVTGVWNDVVSWLR---DAFVSDVRLPI-------------
MLBr_02411|M.leprae_Br4923 MLLIAIGAALIAGVWDDFVSWLR---DAVVSDMRVSI-------------
MSMEG_0972|M.smegmatis_MC2_155 VLLILVGAALVTGLWNEFVSYVR---DAFVSDVRLPI-------------
TH_2250|M.thermoresistible__bu VLLILVGAALVTGLWNEFISWVR---DAFVSDVRLPI-------------
Mflv_2825|M.gilvum_PYR-GCK VLLVAVGIALLTGLWNEVVSWVR---DAFVSNTTLPI-------------
Mvan_5557|M.vanbaalenii_PYR-1 VILVVIGTVFLVTDGTANLGGVLGVDEQFDLQVWLRVMGTSAADPIVLLG
MAB_4286|M.abscessus_ATCC_1997 GMFIAIGVFFLATDGTAALGGLTGSDTQYDVQARLQSLTAGLPNAAVALG
::: :* ::. :. : : :
MMAR_0873|M.marinum_M ---------------------------------------
MUL_0626|M.ulcerans_Agy99 ---------------------------------------
MAV_4618|M.avium_104 ---------------------------------------
Mb0540|M.bovis_AF2122/97 ---------------------------------------
Rv0527|M.tuberculosis_H37Rv ---------------------------------------
MLBr_02411|M.leprae_Br4923 ---------------------------------------
MSMEG_0972|M.smegmatis_MC2_155 ---------------------------------------
TH_2250|M.thermoresistible__bu ---------------------------------------
Mflv_2825|M.gilvum_PYR-GCK ---------------------------------------
Mvan_5557|M.vanbaalenii_PYR-1 VVGASLAWRGHRLWRRRSESD-------ESVTVSGGGGS
MAB_4286|M.abscessus_ATCC_1997 IACAAFVVVLMRLLRARITAAGDARKRSDSTREDADDRR