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M. tuberculosis H37Rv Rv0527 (ccdA)

annotation: POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCDA
coordinates: 617493 - 618272
length: 259

MTGFTEIAAVGPLLVAVGVCLLAGLVSFASPCVVPLVPGYLSYLAAVVGVDEQLPAGVVKPPVAARWRVA
GSAALFVAGFTTVFVLGTVAVLGMTTTLITNQLLLQRVGGVLIVVMGLVFVGFIGALQRQARFTPRQLTS
VAGAPVLGAVFALGWTPCLGPTLTGVITVASATEGASVARGIVLVIAYCLGLGIPFVLLAFGSAWAVAGL
GWLRRHTRAIQIFGGALLIAVGAALVTGVWNDVVSWLRDAFVSDVRLPI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0527ccdA-100% (259)POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCDA
M. tuberculosis H37RvRv2874dipZ6e-1428.95% (228) integral membrane C-type cytochrome biogenesis protein DipZ
M. tuberculosis H37RvRv2877c-1e-1129.96% (227) integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0540ccdA1e-144100.00% (259) cytochrome C-type biogenesis protein CcdA
M. gilvum PYR-GCKMflv_0051-1e-10978.04% (255) cytochrome c biogenesis protein, transmembrane region
M. leprae Br4923MLBr_02411-1e-11478.63% (262) putative cytochrome C-type biogenesis protein
M. abscessus ATCC 19977MAB_3975c-1e-10471.71% (258) putative cytochrome C biogenesis protein CcdA
M. marinum MMMAR_0873ccsA1e-12586.69% (263) cytochrome C-type biogenesis protein, CcsA
M. avium 104MAV_4618-1e-12687.64% (259) cytochrome C biogenesis protein transmembrane region
M. smegmatis MC2 155MSMEG_0972-1e-11480.53% (262) cytochrome C biogenesis protein transmembrane region
M. thermoresistible (build 8)TH_2250ccsA1e-11576.56% (273) POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCDA
M. ulcerans Agy99MUL_0626ccsA1e-12486.31% (263) cytochrome C-type biogenesis protein, CcsA
M. vanbaalenii PYR-1Mvan_0867-1e-11075.88% (257) cytochrome c biogenesis protein, transmembrane region

CLUSTAL 2.0.9 multiple sequence alignment


Rv0527|M.tuberculosis_H37Rv         ------MTGFTEIAAVGPLLVAVGVCLLAGLVSFASPCVVPLVPGYLSYL
Mb0540|M.bovis_AF2122/97            ------MTGFTEIAAVGPLLVAVGVCLLAGLVSFASPCVVPLVPGYLSYL
MLBr_02411|M.leprae_Br4923          ------MTGFTEIAAAGPLLVALGVCMLAGLVSFVSPCVVPLVPGYLSYL
MAV_4618|M.avium_104                ------MTGLTQIAAAGPLLAALGVCLLAGLVSFASPCVVPLVPGYLSYL
MMAR_0873|M.marinum_M               ------MTGFAEVAAAGPLLVALGLCVLAGLVSFASPCVVPLVPGYLSYL
MUL_0626|M.ulcerans_Agy99           ------MTGFAEVAAAGPLLVALGLCVLAGLVSFASPCVVPLVPGYLSYL
MSMEG_0972|M.smegmatis_MC2_155      ------MTGFAEIAAAGPVLLALGVSVLAGLVSFASPCVVPLVPGYLSYL
TH_2250|M.thermoresistible__bu      ------MTGFAELAAAGPVLVAVAISILAGLVSFASPCVVPLVPGYLSYL
Mflv_0051|M.gilvum_PYR-GCK          MNVD----QIDQLTASGPLLLAMGLAALAGLVSFASPCVVPLVPGYLSYL
Mvan_0867|M.vanbaalenii_PYR-1       MTLD----QIDQLTATGPLLLATGLAALAGLVSFASPCVIPLVPGYLSYL
MAB_3975c|M.abscessus_ATCC_199      MILADAGSAFQDAATSGPLLLALGACALAGLVSFASPCVIPLVPGYLSYL
                                             : : :: **:* * . . *******.****:**********

Rv0527|M.tuberculosis_H37Rv         AAVVGV---DEQLP-AGVVK----------PPVAARWRVAGSAALFVAGF
Mb0540|M.bovis_AF2122/97            AAVVGV---DEQLP-AGVVK----------PPVAARWRVAGSAALFVAGF
MLBr_02411|M.leprae_Br4923          AAVVGVS-HEETQPGAGVIK----------TPPAARWRVAGSAVLFVAGF
MAV_4618|M.avium_104                AALVGV----EEQPQAGAVQ----------APPGARWRVAGSAALFVAGF
MMAR_0873|M.marinum_M               AAVVGVDGSGDGRAAGVGVK----------APAGVRWRVAGSALLFVAGF
MUL_0626|M.ulcerans_Agy99           AAVVGVDGSGDGRAAGVGVK----------APAGVRWRVAGSALLFVAGF
MSMEG_0972|M.smegmatis_MC2_155      AAVVGVDDD--PVRTGGER----------VALRSARLRVAGAAALFVAGF
TH_2250|M.thermoresistible__bu      AAVVGVPKEAAPVVTGGPRRDPPADSGAGMSPRSARLRVTGAAALFVAGF
Mflv_0051|M.gilvum_PYR-GCK          AAVVGVD----DGPAGS----------GAVAVKGARLRVAGAAALFVAGF
Mvan_0867|M.vanbaalenii_PYR-1       AAVVGVD----QSAAGSAAP-------GAVAVKGARLRVAGAAGLFVAGF
MAB_3975c|M.abscessus_ATCC_199      AAVVGAD----NGPENG------------AGAQPHRLRVTGSALLFVAGF
                                    **:**.                             * **:*:* ******

Rv0527|M.tuberculosis_H37Rv         TTVFVLGTVAVLGMTTTLITNQLLLQRVGGVLIVVMGLVFVGFIGALQRQ
Mb0540|M.bovis_AF2122/97            TTVFVLGTVAVLGMTTTLITNQLLLQRVGGVLIVVMGLVFVGFIGALQRQ
MLBr_02411|M.leprae_Br4923          TTVFVLDTVAVLGMTTVLTTHQVLLQRVGGVLTIVMGLVFVGLLPALQRQ
MAV_4618|M.avium_104                TAVFVLGTVAVLGMTTTLITNQLLLQRAGGVLTIVMGLVFVGLIPALQRQ
MMAR_0873|M.marinum_M               TTVFVLGTVAVLGMTTTLISNQLVLQRAGGVLTIIMGLVFVGLIPALQRQ
MUL_0626|M.ulcerans_Agy99           TTVFVLGTVAVLGMTTTLISNQLVLQRAGGVLTIIMGLVFVGLIPALQRQ
MSMEG_0972|M.smegmatis_MC2_155      TVVFLLGAVAVLGMTTTLIANQLLLQRIGGVVTIVMGLVFVGFIPALQRQ
TH_2250|M.thermoresistible__bu      TVVFLLGTVAVLGMTTTLITNQVLLQRIGGVITIVMGLVFIGFIPALQRQ
Mflv_0051|M.gilvum_PYR-GCK          TVVFLLGTVAVLGMTTTLITNQLLLQRIGGVITILMGLVFIGLVPVLQRD
Mvan_0867|M.vanbaalenii_PYR-1       TVVFLLGTVAVLGMTTALITNQLLLQRLGGVVTILMGLVFIGLVPVLQRD
MAB_3975c|M.abscessus_ATCC_199      TAVFLLGTVAVMGMTTSLITNQVLLQRIGGVVTIAMGLVFIGLVPALQRD
                                    *.**:*.:***:**** * ::*::*** ***: : *****:*:: .***:

Rv0527|M.tuberculosis_H37Rv         ARFTPRQLTSVAGAPVLGAVFALGWTPCLGPTLTGVITVASATEGASVAR
Mb0540|M.bovis_AF2122/97            ARFTPRQLTSVAGAPVLGAVFALGWTPCLGPTLTGVITVASATEGASVAR
MLBr_02411|M.leprae_Br4923          VQFSLRQLTTVAGAPVLGTVFALGWTPCLGPTLSGVITVAAATDGVNVTR
MAV_4618|M.avium_104                ARFSPRQLTTVAGAPLLGAVFALGWTPCLGPTLAGVITVASATDGASVAR
MMAR_0873|M.marinum_M               ARFSPRQVTTVAGAPLLGAVFALGWTPCLGPTLTGVITVASATDGASVAR
MUL_0626|M.ulcerans_Agy99           ARFSPRQVTTVAGAPLLGAVFALGWTPCLGPTLTGVITVASATNGASVAR
MSMEG_0972|M.smegmatis_MC2_155      ARFTPRQLSTVAGAPLLGAVFALGWTPCLGPTLTGVIAVASATDGATVAR
TH_2250|M.thermoresistible__bu      ARFAPRQWSTVAGAPLLGAVFALGWTPCLGPTLTGVITVASATDGASVAR
Mflv_0051|M.gilvum_PYR-GCK          TRFTPRRISTVGGAPLLGAVFALGWTPCLGPTLTGVIAVASATEGSNVAR
Mvan_0867|M.vanbaalenii_PYR-1       TRFTPRQISTLGGAPLLGAVFALGWTPCLGPTLTGVIAVASATEGSNVAR
MAB_3975c|M.abscessus_ATCC_199      IRFTPRRVSTVAGAPLLGAVFALGWTPCLGPTLTGVVAVASATEGADVAR
                                     :*: *: :::.***:**:**************:**::**:**:*  *:*

Rv0527|M.tuberculosis_H37Rv         GIVLVIAYCLGLGIPFVLLAFGSAWAVAGLGWLRRHTRAIQIFGGALLIA
Mb0540|M.bovis_AF2122/97            GIVLVIAYCLGLGIPFVLLAFGSAWAVAGLGWLRRHTRAIQIFGGALLIA
MLBr_02411|M.leprae_Br4923          GILLVIAYCMGLGIPFVLLASGSAQAVAGLRWLRQYGRAIQVFGGMLLIA
MAV_4618|M.avium_104                GIVLVIAYCLGLGIPFVLLAFGSAGAVAGLGWLRRHTRAIQIFGGVLLIT
MMAR_0873|M.marinum_M               GIVLVIAYCLGLGIPFVLLAFGSAGAVAGLGWLRRHTRAIQIFGGVLLIA
MUL_0626|M.ulcerans_Agy99           GIVLVIAYCLGLGIPFVLLAFGSAGAVAGLGWLRRHTRAIQIFGGVLLIV
MSMEG_0972|M.smegmatis_MC2_155      GVVLVLAYCLGLGIPFVLLALGSARAVQGLGWLRRHTRTIQIFGGVLLIL
TH_2250|M.thermoresistible__bu      GVVLVIAYCLGLGIPFILLAFGSARAVQGLGWLRRNTRTIQIFGGVLLIL
Mflv_0051|M.gilvum_PYR-GCK          GVVLVIAYCLGLGIPFVLLAFGSARAVAGLGWLRRNTRTIQILGGVLMIL
Mvan_0867|M.vanbaalenii_PYR-1       GVVLVIAYCLGLGIPFVLLAFGSARAVAGLGWLRRHTRTIQVLGGVLMIL
MAB_3975c|M.abscessus_ATCC_199      GIALVIAYCLGLGMPFLLLAFGSARAVRGMDWLRRHTRMIQVIGGIALLA
                                    *: **:***:***:**:*** *** ** *: ***:  * **::**  :: 

Rv0527|M.tuberculosis_H37Rv         VGAALVTGVWNDVVSWLRDAFVSDVRLPI
Mb0540|M.bovis_AF2122/97            VGAALVTGVWNDVVSWLRDAFVSDVRLPI
MLBr_02411|M.leprae_Br4923          IGAALIAGVWDDFVSWLRDAVVSDMRVSI
MAV_4618|M.avium_104                VGALLVTGLWNDFVSWLRDAFVSDVRLPI
MMAR_0873|M.marinum_M               VGLALVTGVWNDVVSWLRDAFVSDVRLPI
MUL_0626|M.ulcerans_Agy99           VGLALVTGVWNDVVSWLRDAFVSDVRLPI
MSMEG_0972|M.smegmatis_MC2_155      VGAALVTGLWNEFVSYVRDAFVSDVRLPI
TH_2250|M.thermoresistible__bu      VGAALVTGLWNEFISWVRDAFVSDVRLPI
Mflv_0051|M.gilvum_PYR-GCK          VGAALVTGLWNEFVSWVRDAFVSDVRLPI
Mvan_0867|M.vanbaalenii_PYR-1       VGAALVTGLWNDFVSWIRDAFVSDVRLPI
MAB_3975c|M.abscessus_ATCC_199      VGVALITGVWADFVAWVRDSFVSDARLPI
                                    :*  *::*:* :.::::**:.*** *:.*