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MRVLKSDSGYVLEGDWDGQDAANAFLNHLGGRGFSAATVRAYAFDVANLSRFLVQQAVGLVAVDAPLVFD WIDWQGVRRTDQPTSGHRSSTPPAASTVNRRVAAVRALFEYLVMTGVCTDNPVPSPRRGQGLRQSQRGLL GHLGPGRARSGGRLVRQPQRLPESLSTNDVDAFLATLATHRDRAMVLVMLLGGLRSAEARGLLLTDVDMG RRRLRVIGKGGKERHVPVDAAFFTELAAYLRWERPPGLATPQCFVVLRGPTTGAPVSEAGLRSLFRRHRE TSGATRVRPHRLRHTYGTELSAAGIDLLTLRALMGHVSPETTARYVHLSIEQLAAEYGAARATLAGARQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5497 | - | - | 100% (349) | phage integrase family protein |
| M. vanbaalenii PYR-1 | Mvan_3589 | - | 0.0 | 100.00% (349) | phage integrase family protein |
| M. vanbaalenii PYR-1 | Mvan_0455 | - | 0.0 | 100.00% (349) | phage integrase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2918c | xerC | 9e-20 | 26.95% (308) | site-specific tyrosine recombinase XerC |
| M. gilvum PYR-GCK | Mflv_4645 | - | 2e-59 | 39.43% (350) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv2894c | xerC | 9e-20 | 26.95% (308) | site-specific tyrosine recombinase XerC |
| M. leprae Br4923 | MLBr_01365 | xerD | 6e-20 | 29.79% (329) | site-specific tyrosine recombinase XerD |
| M. abscessus ATCC 19977 | MAB_3204c | xerC | 3e-20 | 29.10% (323) | site-specific tyrosine recombinase XerC |
| M. marinum M | MMAR_1433 | - | 7e-56 | 39.94% (333) | site-specific integrase |
| M. avium 104 | MAV_3746 | xerC | 1e-24 | 31.66% (319) | site-specific tyrosine recombinase XerC |
| M. smegmatis MC2 155 | MSMEG_2515 | xerC | 6e-22 | 28.43% (313) | site-specific tyrosine recombinase XerC |
| M. thermoresistible (build 8) | TH_2462 | - | 1e-143 | 72.49% (349) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | MUL_2065 | xerC | 9e-23 | 28.80% (309) | site-specific tyrosine recombinase XerC |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2918c|M.bovis_AF2122/97 -------------------------MQAILDEFDEYLALQCGRSVHTRRA
Rv2894c|M.tuberculosis_H37Rv -------------------------MQAILDEFDEYLALQCGRSVHTRRA
MAV_3746|M.avium_104 ---------------------MPD-SEPILEEFDEYLALQCGRSAHTRRA
MUL_2065|M.ulcerans_Agy99 ---------------------MPDNSEAILEEFDEYLALQCGRSAHTRRA
MAB_3204c|M.abscessus_ATCC_199 ---------------------MTPQLAAILDEFAEHLALERGRSVHTQRA
MSMEG_2515|M.smegmatis_MC2_155 -------------------------MESVLDQFDAYLGLERGHSDHTRRA
MLBr_01365|M.leprae_Br4923 --------------------MTTAALQTQLQGYLDYLIIERSIAANTLSS
Mvan_5497|M.vanbaalenii_PYR-1 ------MRVLKSDS-GYVLEG-DWDGQDAANAFLNHLGG-RGFSAATVRA
TH_2462|M.thermoresistible__bu ----MTVRVRTHGD-GYAIDG-QWEGSAAANAFLTHLAG-RGFSAATVRA
Mflv_4645|M.gilvum_PYR-GCK MTIQHQLRLQAGTDVAWVLSGPGCGKYALVNEYLRYLAD-RNYSPRTLRA
MMAR_1433|M.marinum_M --MTKELAAVVDDDGVWQLRGTAAEQFGLVNEFLGYLAD-RNFSPRTCRA
: : :* . : * :
Mb2918c|M.bovis_AF2122/97 YLGDLRSLFAFLADRG--SSLDALTLSVLRSWLAATAG------------
Rv2894c|M.tuberculosis_H37Rv YLGDLRSLFAFLADRG--SSLDALTLSVLRSWLAATAG------------
MAV_3746|M.avium_104 YLGDLRSLLAFAGERG--TGLDGLSLPLLRSWLSAAAA------------
MUL_2065|M.ulcerans_Agy99 YLGDLRSLLDYLAGRG--ADLRALSLPVLRSWLATAAG------------
MAB_3204c|M.abscessus_ATCC_199 YRGDLTLLFDHLSASNPEATLADLSLPVLRSWLGAQAR------------
MSMEG_2515|M.smegmatis_MC2_155 YRGDLTALFDFVEQRTGERSLARVSLPLLRSWLAEQSA------------
MLBr_01365|M.leprae_Br4923 YRRDLIRYSKHLSDRG-IEDLAKVGEHDVSEFLVALRRGD----------
Mvan_5497|M.vanbaalenii_PYR-1 YAFDVANLSRFLVQQA--VGLVAVDAPLVFDWID-WQGVRRTDQPTSGHR
TH_2462|M.thermoresistible__bu YAFDVLNLARFLLDRD--LTVAAVTPVTVFEWID-WQDVRREPRPGMATR
Mflv_4645|M.gilvum_PYR-GCK YGYDLLAFCRWLGSVD--VELSSVTTETVLDFMRHCRQTPIAGRP-TNVV
MMAR_1433|M.marinum_M YAYDLLAFARWLRDEQ--LGVAEVNVDVLLRFLTACREATLPGRPGGNVY
* *: : : : ::
Mb2918c|M.bovis_AF2122/97 -------AGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQ------
Rv2894c|M.tuberculosis_H37Rv -------AGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQ------
MAV_3746|M.avium_104 -------GGVARTTLARRTSAVKAFTAWAVRRGLLTADPAARLQ------
MUL_2065|M.ulcerans_Agy99 -------AGAARTTLARRTSAVKAFTAWAVRRGLLATDPAARLQ------
MAB_3204c|M.abscessus_ATCC_199 -------QGAARSTVARRTSAVKIFTAWATRRGLLPTDPAIRLQ------
MSMEG_2515|M.smegmatis_MC2_155 -------SGAARTTLARRTSSVKTFCAWALRRGLIGVDPAARLQ------
MLBr_01365|M.leprae_Br4923 --PDSGVAALSAVSAARALIAVRGLHRFAVAEGLVDLDVARAVR------
Mvan_5497|M.vanbaalenii_PYR-1 SSTPP-----AASTVNRRVAAVRALFEYLVMTGVCTDNPVPSPRRGQGLR
TH_2462|M.thermoresistible__bu GDRGA-----AASTINRRVAAVRALFEYLVMTRMRADNPVPSPRRGQGLR
Mflv_4645|M.gilvum_PYR-GCK SMTGTRLDRYSSTTINHRLAALTGLFTFRELRDPGLRTPIPSGREARRVS
MMAR_1433|M.marinum_M SIRDGRNQGYAPATINRRLAAISSLFAFREMRDPDARSLVGSSRAARLRS
: : : :: : : :
Mb2918c|M.bovis_AF2122/97 ------------VPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRD
Rv2894c|M.tuberculosis_H37Rv ------------VPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRD
MAV_3746|M.avium_104 ------------VPKTHRTLPAVLRQDQALGAMAAAKNGAAQGDPIALRD
MUL_2065|M.ulcerans_Agy99 ------------VPKAHRTLPAVLRQDQALAAMTAAKSSAQQGDPLALRD
MAB_3204c|M.abscessus_ATCC_199 ------------QPKSRRTLPAVLRQDQAAAAMEAAHSGAEQDDPMALRD
MSMEG_2515|M.smegmatis_MC2_155 ------------VPKARRTLPAVLRRDQALDALDAVNSGAQEGDPIALRD
MLBr_01365|M.leprae_Br4923 ------------PPTPGRRLPKSLTVDEVLALLESVGGESRADGPLVLRN
Mvan_5497|M.vanbaalenii_PYR-1 QSQR-GLLGHLGPGRARSGGRLVRQPQRLPESLSTNDVDAFLATLATHRD
TH_2462|M.thermoresistible__bu PQAR-GLLGHLGPGRPRAGGRLVRQPRLLPESLDADAVEQFVASLRTHRD
Mflv_4645|M.gilvum_PYR-GCK AEERNGLLGHLVRPKRRSALR-LREPRRLPRALNRRETAELLSSLRTWRD
MMAR_1433|M.marinum_M RGERSGLLAHTAKPKSRSQLR-VREPRWLPRGLSREESAALLGSFRSWRD
: *:
Mb2918c|M.bovis_AF2122/97 RLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTVPFGQPA
Rv2894c|M.tuberculosis_H37Rv RLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTVPFGQPA
MAV_3746|M.avium_104 RLIVEMLYATGIRVSELCGLDIDDVDTGRRLVRVLGKGNKQRSVPFGAPA
MUL_2065|M.ulcerans_Agy99 RLIVELLYATGIRVSELRGLDIDDVDTGHRLVRVLGKGNKQRTAPFGQPA
MAB_3204c|M.abscessus_ATCC_199 RLIVEMLYATGIRVSELCGLDIDDIDRPRKVLRVLGKGDKERTVPFGDPA
MSMEG_2515|M.smegmatis_MC2_155 RLIVELLYATGIRVSELCGLDIDDIDTSRRVVRVLGKGNKQRTVPFGEPA
MLBr_01365|M.leprae_Br4923 RALLELLYSTGSRISEAVGLDVDDVDTQARTVLLQGKGGKQRLVPVGRPA
Mvan_5497|M.vanbaalenii_PYR-1 RAMVLVMLLGGLRSAEARGLLLTDVDMGRRRLRVIGKGGKERHVPVDAAF
TH_2462|M.thermoresistible__bu RAMVWAMLFGGLRSAEVRSLRLADVDFGRRRLRVLGKGSKERVVPVDAVF
Mflv_4645|M.gilvum_PYR-GCK RALAGLMLLSGLRSGELLTLDVTDVDIGARWVKVMGKGAKERRVPLDVEV
MMAR_1433|M.marinum_M RAIGGLMLLSGLRSAEVLGLRVSDIDIARRWVRVLGKGGKERSVPIDTDV
* : : * * .* * : *:* : : : *** *:* .*..
Mb2918c|M.bovis_AF2122/97 ADALHAWLVDGRRALVTAESG----HALLLGARGRRLDVRQARTAVHQTV
Rv2894c|M.tuberculosis_H37Rv ADALHAWLVDGRRALVTAESG----HALLLGARGRRLDVRQARTAVHQTV
MAV_3746|M.avium_104 GEALHAWLADGRPALANAESG----PALLLGARGRRLDVRQARTVVHQTI
MUL_2065|M.ulcerans_Agy99 AEALQAWLADGRPALATAESG----PALLLGARGRRLDVRQARTVVHQTI
MAB_3204c|M.abscessus_ATCC_199 ADALSAWLDRGRPHLAVPASG----AALLLGARGRRVDPRQVRTVVHQTM
MSMEG_2515|M.smegmatis_MC2_155 HAALTAWLTEGRPQLSIPESG----PALLLGARGRRLDPRQARTVVHQTV
MLBr_01365|M.leprae_Br4923 VQALDAYLVRGRSDLARRGPGMLATPAIFLNARGGRLSRQSAWQVLQDAA
Mvan_5497|M.vanbaalenii_PYR-1 FTELAAYLRWERPPGLATPQC----FVVLRGPTTGAPVSEAGLRSLFRRH
TH_2462|M.thermoresistible__bu FTELSAYLRLERPPGLATQEC----FVVLRGPTHGSPVTEAGLRSLFRRH
Mflv_4645|M.gilvum_PYR-GCK AGLIQTYLLVERPE-SDSNRL----FLVAKGPHRGQPLTAAGLRTIFRYH
MMAR_1433|M.marinum_M AGAIQTYLLAERPE-TDADEL----FVVAKGAHRGRPLTAAGLRTVFRYH
: ::* * : .. :
Mb2918c|M.bovis_AF2122/97 AAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHV
Rv2894c|M.tuberculosis_H37Rv AAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHV
MAV_3746|M.avium_104 AAVSGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHV
MUL_2065|M.ulcerans_Agy99 AAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHV
MAB_3204c|M.abscessus_ATCC_199 SAVPGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHSTLATTQLYTHV
MSMEG_2515|M.smegmatis_MC2_155 SAVNGAPDIGPHGLRHSAATHLLEGGADLRIVQELLGHTSLATTQLYTHV
MLBr_01365|M.leprae_Br4923 EHAGITSGVSPHMLRHSFATHLLEGGADIRVVQELMGHASVTTTQIYTLV
Mvan_5497|M.vanbaalenii_PYR-1 RETSGATRVRPHRLRHTYGTELSAAGIDLLTLRALMGHVSPETTARYVHL
TH_2462|M.thermoresistible__bu RVLSGATRVRPHRLRHTYGTELASAGIDLMALRELMGHVSPETTAGYVHL
Mflv_4645|M.gilvum_PYR-GCK RIKSGVLAGHPHALRHTFGTAMAEAGVDLAVMQALLGHAHIDTTARYIHL
MMAR_1433|M.marinum_M RERSGVAAGHPHALRHSFGTALAEAGVDLSVIQALMGHDHVDSAAAYIHL
. ** ***: .* : .* *: :: *:** :: * :
Mb2918c|M.bovis_AF2122/97 AVARLRAVHERAHPRA-----
Rv2894c|M.tuberculosis_H37Rv AVARLRAVHERAHPRA-----
MAV_3746|M.avium_104 AVSRLRAVHDQAHPRA-----
MUL_2065|M.ulcerans_Agy99 AVSRLRAVHDQAHPRA-----
MAB_3204c|M.abscessus_ATCC_199 TVARLRAVHDQAHPRA-----
MSMEG_2515|M.smegmatis_MC2_155 TVERLRAVHDQAHPRA-----
MLBr_01365|M.leprae_Br4923 TVQALREVWAGAHPRAK----
Mvan_5497|M.vanbaalenii_PYR-1 SIEQLAAEYGAARATLAGARQ
TH_2462|M.thermoresistible__bu SVAQLAAEYGAARASLAGTRR
Mflv_4645|M.gilvum_PYR-GCK APTHVKAEYDAARTRLRSHT-
MMAR_1433|M.marinum_M APTFLREEFDAARARLRARS-
: : *:.