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LDSVEEVREALAGEGYIADERLATTVFLQTRLDKPLLIEGPAGVGKTELAKVLAAATGRRLLRLQCYEGQ DETKALYEWDYGKQLLYTQILREKIGQLVSDAADLTEAVERIGAQESVFFSDRFLAPRPLLEAVRSPEPV VLLVDEIDRADEALEAVLLELLGEYQVSVPEIGTFRAVHAPYVVLTSNNTRDLAAALKRRCLHLFLDYPA AERELEIVRSKNTGLSDALAAQLVDIVRGLRELELRKAPSISETIDWARTLAVLGVDELSAQVLSDTVSV VVKYDKDVRKSLDALPRLVDPNATVPEQHSHGHGHGHGHDHDHHGPEHHDHDHGDDGRAARAAKDQPGRF TDGYYGTPRRAEQAATAGSLGRRRAL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5478 | - | - | 100% (377) | ATPase |
| M. vanbaalenii PYR-1 | Mvan_3933 | - | 8e-71 | 48.96% (288) | ATPase |
| M. vanbaalenii PYR-1 | Mvan_4196 | - | 3e-08 | 23.47% (277) | ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2450c | - | 4e-70 | 47.26% (292) | hypothetical protein Mb2450c |
| M. gilvum PYR-GCK | Mflv_2645 | - | 3e-70 | 47.60% (292) | ATPase |
| M. tuberculosis H37Rv | Rv2426c | - | 9e-71 | 47.60% (292) | hypothetical protein Rv2426c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1619 | - | 1e-70 | 46.28% (296) | hypothetical protein MAB_1619 |
| M. marinum M | MMAR_3752 | - | 1e-70 | 47.60% (292) | hypothetical protein MMAR_3752 |
| M. avium 104 | MAV_1748 | - | 2e-70 | 47.95% (292) | ATPase associated with various cellular activities |
| M. smegmatis MC2 155 | MSMEG_6241 | - | 1e-80 | 54.74% (285) | ATPase associated with various cellular activities, AAA-5 |
| M. thermoresistible (build 8) | TH_0791 | - | 4e-72 | 47.95% (292) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3695 | - | 7e-71 | 47.60% (292) | hypothetical protein MUL_3695 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2450c|M.bovis_AF2122/97 ---MTVPARP----------TPLFADIADVSRRLAETGYLPDTATATAVF
Rv2426c|M.tuberculosis_H37Rv ---MTVPARP----------TPLFADIADVSRRLAETGYLPDTATATAVF
MMAR_3752|M.marinum_M ---MSVPARS----------VPLFADIADVSRRLAQTGYLPDTATATAVF
MUL_3695|M.ulcerans_Agy99 ---MSVPARS----------VPLFADIADVSRRLAQTGYLPDTATATAVF
MAV_1748|M.avium_104 ---MSVPARP----------RPLFADIDDVSRRLAETGYLPDTATATAVF
Mflv_2645|M.gilvum_PYR-GCK ---MSVPASI----------QPLFADIDDVARRLAETGYLPDTATATAVF
TH_0791|M.thermoresistible__bu ---VSLPARS----------APLFADIDDVSRRLAETGYLPDTATATAVY
MAB_1619|M.abscessus_ATCC_1997 ---MSDPLRPSGSSQSRTQTAPLFTSIDDVTTRLAETGYLADTATATAVF
Mvan_5478|M.vanbaalenii_PYR-1 ----------------------MLDSVEEVREALAGEGYIADERLATTVF
MSMEG_6241|M.smegmatis_MC2_155 MTTATIPVRDE---------PITFGSAAELSAALHEQDYIADTDLATVVH
: . :: * .*:.* **.*.
Mb2450c|M.bovis_AF2122/97 LADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARALY
Rv2426c|M.tuberculosis_H37Rv LADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARALY
MMAR_3752|M.marinum_M LADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARALY
MUL_3695|M.ulcerans_Agy99 LADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARALY
MAV_1748|M.avium_104 LADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARALY
Mflv_2645|M.gilvum_PYR-GCK LADRLGKPLLVEGPAGVGKTELARAIAQSTGSGLVRLQCYEGVDESRALY
TH_0791|M.thermoresistible__bu LADRLGKPLLVEGPAGVGKTELARAVAQATGSELVRLQCYEGVDEARALY
MAB_1619|M.abscessus_ATCC_1997 LADRLGKPLLVEGPAGVGKTELARAVAHTTGSGLVRLQCYEGVDEARALY
Mvan_5478|M.vanbaalenii_PYR-1 LQTRLDKPLLIEGPAGVGKTELAKVLAAATGRRLLRLQCYEGQDETKALY
MSMEG_6241|M.smegmatis_MC2_155 LATALDRPLLLEGPAGVGKTELAKALAAAGGRRLIRLQCYEGLDDNRVLY
* *.:***:************:.:* : * *:******* *: :.**
Mb2450c|M.bovis_AF2122/97 EWNHAK-----QILRIQAGSG-----DWEATKTDV-------LSEEFLLQ
Rv2426c|M.tuberculosis_H37Rv EWNHAK-----QILRIQAGSG-----DWEATKTDV-------FSEEFLLQ
MMAR_3752|M.marinum_M EWNHAK-----QILRIQSGSG-----DWEATKDDV-------FSEEFLLQ
MUL_3695|M.ulcerans_Agy99 EWNHAK-----QILRIQSGSG-----DWEATKDDV-------FSEEFLLQ
MAV_1748|M.avium_104 EWNHAK-----QILRIQAGSG-----DWDQTKTDV-------FSEEFLLQ
Mflv_2645|M.gilvum_PYR-GCK EWNHAK-----QILRIQAGHG-----DWDQTRDDV-------FSEEFLLT
TH_0791|M.thermoresistible__bu EWNHAK-----QILRIQAGNAGAGGEAWERTKDDV-------FSEEFLLS
MAB_1619|M.abscessus_ATCC_1997 EWNHAK-----QILRIQAGSG-----DWDETKTDV-------FAEEFLLS
Mvan_5478|M.vanbaalenii_PYR-1 EWDYGKQLLYTQILREKIGQLVSDAADLTEAVERIGAQESVFFSDRFLAP
MSMEG_6241|M.smegmatis_MC2_155 EWDYAKQLLHVQMLRDRITAATNGIEDIDEASRYLAGRDFGLYSEAFLSV
**::.* *:** : : : :: **
Mb2450c|M.bovis_AF2122/97 RPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTLTA
Rv2426c|M.tuberculosis_H37Rv RPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTLTA
MMAR_3752|M.marinum_M RPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTLTA
MUL_3695|M.ulcerans_Agy99 RPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTLTA
MAV_1748|M.avium_104 RPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTLTA
Mflv_2645|M.gilvum_PYR-GCK RPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTITA
TH_0791|M.thermoresistible__bu RPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTITA
MAB_1619|M.abscessus_ATCC_1997 RPLLTAIRREDPTVLLIDETDKADIEIEGLLLEVLSDFAVTIPELGTIAA
Mvan_5478|M.vanbaalenii_PYR-1 RPLLEAVRSPEPVVLLVDEIDRADEALEAVLLELLGEYQVSVPEIGTFRA
MSMEG_6241|M.smegmatis_MC2_155 RPLLDAVLSEEPVVLLIDEVDRTEEAMEALLLEILAERQVTIPEIGTFTA
**** *: :*.***:** *::: :*.:***:*.: *::**:**: *
Mb2450c|M.bovis_AF2122/97 TRAPFVLLTSNATRELSEALKRRCLYLHIDFPTPELERRILLSRVPELPE
Rv2426c|M.tuberculosis_H37Rv TRAPFVLLTSNATRELSEALKRRCLYLHIDFPTPELERRILLSRVPELPE
MMAR_3752|M.marinum_M ARAPFVLLTSNATRELSEALKRRCLFLHIDFPTPEMERRILLSRVPELPE
MUL_3695|M.ulcerans_Agy99 TRAPFVLLTSNATRELSEALKRRCLFLHIDFPTPEMERRILLSRVPELPE
MAV_1748|M.avium_104 ERPPFVVLTSNATRELSEALKRRCLFLHIDFPSPDLERRILLSRVPELPA
Mflv_2645|M.gilvum_PYR-GCK ERRPLVVLTSNATRELSEALKRRCLFLHIDFPDPDLERRILLSRVPELPE
TH_0791|M.thermoresistible__bu ERIPFVVLTSNATRELSEALKRRCLFLHIDFPDPDLERRILLSRVPELPE
MAB_1619|M.abscessus_ATCC_1997 SRKPFVLLTSNATRELSEALKRRCLFLHIDFPDAELERRILLKRVPELPA
Mvan_5478|M.vanbaalenii_PYR-1 VHAPYVVLTSNNTRDLAAALKRRCLHLFLDYPAAERELEIVRSKNTGLSD
MSMEG_6241|M.smegmatis_MC2_155 RTVPWVVLTSNDTRELSSALKRRCLHYHLGFPTPQREREIVGVRAPHVEP
* *:**** **:*: *******. .:.:* .: * .*: : . :
Mb2450c|M.bovis_AF2122/97 HFAEELVRIIGVLRGMQLKKVPSIAETIDWGRTVLALGLDTIDDAVVAAT
Rv2426c|M.tuberculosis_H37Rv HFAEELVRIIGVLRGMQLKKVPSIAETIDWGRTVLALGLDTIDDAVVAAT
MMAR_3752|M.marinum_M HIAEELVRIIGVLRGMQLKKLPSIAETIDWGRTVLALGLDTIDDAVVAAT
MUL_3695|M.ulcerans_Agy99 HIAEELVRIIGVLRGMQLKKLPSIAETIDWGRTVLALGLDTIDDAVVAAT
MAV_1748|M.avium_104 HLADELVRIIGVLRGMQLKKVPSIAETIDWGRTLLALGLDTIDDAVVAAT
Mflv_2645|M.gilvum_PYR-GCK RLAEELVRIIGVLRGMQLKKLPSVAETIDWARTVLALGMDTIDDEVIAAT
TH_0791|M.thermoresistible__bu RIASELVRIVGVLRGMQLKKLPSVAETIDWARTVLALGMDTIDDEMIAAT
MAB_1619|M.abscessus_ATCC_1997 SLAEELVRIIGVLRNMQLKKVPSVAETIDWGRTILALGLDTLDDAVIAST
Mvan_5478|M.vanbaalenii_PYR-1 ALAAQLVDIVRGLRELELRKAPSISETIDWARTLAVLGVDELSAQVLSDT
MSMEG_6241|M.smegmatis_MC2_155 SVVADVVELARTLRELPLRKSPSISEVVDGARAAALLGTEASHPLLLST-
.. ::* : ** : *:* **::*.:* .*: ** : :::
Mb2450c|M.bovis_AF2122/97 LGVVLKHQSDQQRATGEL--RLN---------------------------
Rv2426c|M.tuberculosis_H37Rv LGVVLKHQSDQQRATGEL--RLN---------------------------
MMAR_3752|M.marinum_M LGVVLKHQSDQQRATGEL--RLN---------------------------
MUL_3695|M.ulcerans_Agy99 LGVVLKHQSDQQRATGEL--RLN---------------------------
MAV_1748|M.avium_104 LGVVLKHQSDQQRATGEL--RLN---------------------------
Mflv_2645|M.gilvum_PYR-GCK LGVVLKHQSDQIKAAGEL--RLN---------------------------
TH_0791|M.thermoresistible__bu LGVVLKHQSDQQRAISEL--KLN---------------------------
MAB_1619|M.abscessus_ATCC_1997 LGVVLKHHSDQQRAAGEL--RLN---------------------------
Mvan_5478|M.vanbaalenii_PYR-1 VSVVVKYDKDVRKSLDALP-RLVDPNATVPEQHSHGHGHGHGHDHDHHGP
MSMEG_6241|M.smegmatis_MC2_155 ---LVKFTSDREIALRHLGGGLSDNLSGVGAQP-----------------
::*. .* : * *
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_5478|M.vanbaalenii_PYR-1 EHHDHDHGDDGRAARAAKDQPGRFTDGYYGTPRRAEQAATAGSLGRRRAL
MSMEG_6241|M.smegmatis_MC2_155 ------------VEPSKPAEPATVAS----RPANTTTAVFRGRGGGRR--