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VDMDSAVLNPLAPSPHGVWSSHGVRVLRRRGPHRPHSAPGTVCTPRFCSARRGGLLTVEHDLTPDELCDE LAVLLADQLVDSGALQGQSEFELVFTGVVRSTVDGGLPAWLRFYRNSLNKLENGSTAFAPIHSHAADLVR GGRLIDLGSCFGFFPLRLARYGIDVLATDLNDNAMRLLEQVSSRLCRPLTTMACDAADVPLPDGSADTVT ALHLVEHLPDPLVDKIIDEAVRLARRRVIVAVPFEDQPRECYGHIQRFDVRRLQHMAGEVVRRHPRLSAA VHEFHGGWLILDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5473 | - | - | 100% (293) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1100 | - | 1e-05 | 29.94% (167) | methyltransferase type 11 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3364 | - | 1e-05 | 30.48% (105) | hypothetical protein MAB_3364 |
| M. marinum M | MMAR_2924 | - | 2e-06 | 25.90% (166) | SAM-dependent methyltransferase |
| M. avium 104 | MAV_2756 | - | 1e-05 | 25.77% (163) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_6237 | - | 1e-109 | 65.28% (288) | hypothetical protein MSMEG_6237 |
| M. thermoresistible (build 8) | TH_0087 | - | 2e-05 | 24.54% (163) | methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_1280 | - | 6e-05 | 28.81% (118) | hypothetical protein MUL_1280 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1100|M.gilvum_PYR-GCK -----MLTVDFDRLGVGAGTKVIDVGCGAGR----------------HTF
TH_0087|M.thermoresistible__bu -----MLTVDYDRLGIGPGVSVIDVGCGLGR----------------HSF
MMAR_2924|M.marinum_M -----MLTVDFDRLGIGPGATVIDVGCGAGR----------------HAF
MAV_2756|M.avium_104 -----MLTVDFDRLGIGPSSKVIDVGCGAGR----------------HAF
Mvan_5473|M.vanbaalenii_PYR-1 MD---MDSAVLNPLAPSPHGVWSSHGVRVLRRRGPHRPHSAPGTVCTPRF
MSMEG_6237|M.smegmatis_MC2_155 MDVAVLGPALLDPFAPAPQGIWSGNGVRVQRRRGPHRAHAA---VCTPRF
MAB_3364|M.abscessus_ATCC_1997 -----MNSHLTDPHPADP---LRTSGPSAED----------------PDA
MUL_1280|M.ulcerans_Agy99 -------MSAVQPFSEKLSAKLNDMREVLRP-------------------
:
Mflv_1100|M.gilvum_PYR-GCK EAFRRG-ADVIGFDQSASDLN-----------DVDEILQAMKEQGEAPAS
TH_0087|M.thermoresistible__bu EAYRRG-AHIVAFDQNAEELN-----------EVDTILQAMAEQREAPAG
MMAR_2924|M.marinum_M EAYRCG-ADVVAFDRDAAELR-----------AVDTMLRAMAQTGEAPAA
MAV_2756|M.avium_104 EAYRRG-ADVVAFDQNEAELR-----------SVDTVLRAMADSGEAPAG
Mvan_5473|M.vanbaalenii_PYR-1 CSARRGGLLTVEHDLTPDELCDELAVLLADQLVDSGALQGQSEFELVFTG
MSMEG_6237|M.smegmatis_MC2_155 CAHREGDALTVEHDLTPDELSDELAVLLTEELGATGVLHGQPDFESVFTG
MAB_3364|M.abscessus_ATCC_1997 TLALTGERTVPGIAEENYWFR-----------RHEVVYERLSSLCAGRRV
MUL_1280|M.ulcerans_Agy99 ---------AERLRQQAHALG--------------------GHLGKGDSV
:
Mflv_1100|M.gilvum_PYR-GCK AKGEAVKG--DALELPYADGTFDCVIASEILEHVPADDKAISELV-RVLK
TH_0087|M.thermoresistible__bu ARAEVVKG--DALDLPYADGTFDRVIASEILEHVPEDDRAIAELV-RVLK
MMAR_2924|M.marinum_M ASAKVVLG--DALALPYPDGTFDCVIASEILEHVPQDDAAIAELV-RVLK
MAV_2756|M.avium_104 ASATVVVG--DALKLPYPDQTFDCVIASEILEHIPHDDAAIAELI-RVLK
Mvan_5473|M.vanbaalenii_PYR-1 VVRSTVDGGLPAWLRFYRNSLNKLENGSTAFAPIHSHAADLVRGG-RLID
MSMEG_6237|M.smegmatis_MC2_155 VVRSTVDGGMQAWLRFYRNSLHALESGTAAFAPIHQHATELIIGR-RVLD
MAB_3364|M.abscessus_ATCC_1997 LEAGSGEGYGADMLAQVAQHVIGLDYDESAIAHVKARYPRVDMRAGNLAD
MUL_1280|M.ulcerans_Agy99 LDVGCGTG----YLSAYLQQMYGISPSGIDVKDVRRTEIPFREFN-----
* : . : .
Mflv_1100|M.gilvum_PYR-GCK PG---GALAITVPRWLPERICWA---LSD-EYHANEGGHIRIYR-ADELR
TH_0087|M.thermoresistible__bu PG---GKLVVTVPRWLPERICWL---LSD-EYHANEGGHVRIYR-ADELR
MMAR_2924|M.marinum_M VG---GTLAISVPRWLPERVCWL---LSD-EYHSNEGGHVRVYR-ASELR
MAV_2756|M.avium_104 VG---GTLAVSVPRWLPERVCWL---LSD-EYHSNEGGHVRIYR-ASDLR
Mvan_5473|M.vanbaalenii_PYR-1 LGSCFGFFPLRLARYGIDVLATD---LNDNAMRLLEQVSSRLCRPLTTMA
MSMEG_6237|M.smegmatis_MC2_155 LGSCFGFFPLRLSRNGFDATATD---LSAPTMNLLARVSPKLHRPVRTVT
MAB_3364|M.abscessus_ATCC_1997 LPLADGSVDVVVNFQVIEHLWDQGQFIRECARVLRPGGSLLISTPNRITF
MUL_1280|M.ulcerans_Agy99 ------GTSIPFPDRSFDHVVLSEVLHHSHDPVALIKQCYRVARRSIIVF
: . : :
Mflv_1100|M.gilvum_PYR-GCK DKVLAHGLTL-THTHHSHALHSPFWWLKCAVGTEKND----HPAVAAYHK
TH_0087|M.thermoresistible__bu DKITRHGLRL-THRHHAHALHSPFWWLKCAVGTNNDR----HFAVRAYHQ
MMAR_2924|M.marinum_M EKITRHPMAL-THAHHAHALHSPFWWLKCAVGVSNAD----HPLVSAYHK
MAV_2756|M.avium_104 AKILSGGMTL-THAHHAHALHSPFWWLKCAVGVHNTD----HRAVAAYHK
Mvan_5473|M.vanbaalenii_PYR-1 CDAADVPLPD-GSADTVTALHLVEHLPDPLVDKIIDE----AVRLARRRV
MSMEG_6237|M.smegmatis_MC2_155 CDAAGVPLPD-AVADTVTALHLLEHLDPDAGDAVLAE----ALRLARRRV
MAB_3364|M.abscessus_ATCC_1997 SPGRDTPLNP-FHTRELNGAELTELLEENGFSLESMNGVFHGPRLRELDA
MUL_1280|M.ulcerans_Agy99 EDMPDGRLGKGILFLHVHVFARYYRYPFRPATIGSYR---SALNWLGDNA
:
Mflv_1100|M.gilvum_PYR-GCK LLVWDMMSQPW-----LTRTAEAALNPLIGKSVALYFRKP--ADTDA---
TH_0087|M.thermoresistible__bu LLVWDMVRRPW-----VTRWAEEMLNPLIGKSVALYFDKPEVAGADS---
MMAR_2924|M.marinum_M LLVWDLMRRPR-----VTRMAESVLNPLVGKSVAMYFDKRESAQSPADLG
MAV_2756|M.avium_104 LLVWDLMRRPK-----ITQLAESLLNPLVGKSVAMYFVKRQDAKSQATAG
Mvan_5473|M.vanbaalenii_PYR-1 IVAVPFEDQPRECYGHIQRFDVRRLQHMAGEVVRRHPRLSAAVHEFHGGW
MSMEG_6237|M.smegmatis_MC2_155 IVAVPFEDEPQVCYGHVRRFDTEALQHIAEKITRTHP-VTASVGEHHGGW
MAB_3364|M.abscessus_ATCC_1997 KYGGSIIDAQIERAVAGAPWPQELLADITGLTTEDFEIVDAGERDIDASL
MUL_1280|M.ulcerans_Agy99 SCVLQARQPPE----WLSVYPRELFVYELAESAQW---------------
: .
Mflv_1100|M.gilvum_PYR-GCK ---------
TH_0087|M.thermoresistible__bu ---------
MMAR_2924|M.marinum_M HSVASA---
MAV_2756|M.avium_104 YSIASV---
Mvan_5473|M.vanbaalenii_PYR-1 LILDR----
MSMEG_6237|M.smegmatis_MC2_155 LVLDRY---
MAB_3364|M.abscessus_ATCC_1997 DLVAIAVIP
MUL_1280|M.ulcerans_Agy99 ---------