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M. vanbaalenii PYR-1 Mvan_5313 (-)

annotation: HAD family hydrolase
coordinates: 5692169 - 5692927
length: 252

VSVDLPSELVSALDSAAATTRLLVTSDFDGTLAPIVNNPADARPLPAAAQALVALADLAATTTALISGRA
LETLRELSSMPATVHLIGSHGAEFDSGFAHDIDHDLLRAITDRLRAIASDKPGVAVETKPASVALHVRNA
SPADGEAALAAAWEAAPEWEAHVTTGKAVLEFAVIDTDKGAAVDILRGECDATAVVFFGDDVTDEKAFAR
LRRSDVGVKVGPGESAAGYRIDSPDAVAAALEHLVASRKRLA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_5313--100% (252)HAD family hydrolase
M. vanbaalenii PYR-1Mvan_4107-3e-2030.56% (252) HAD family hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2029otsB17e-2034.73% (262) trehalose-6-phosphate phosphatase OtsB1
M. gilvum PYR-GCKMflv_1458-1e-10075.81% (248) HAD family hydrolase
M. tuberculosis H37RvRv2006otsB17e-2034.73% (262) trehalose-6-phosphate phosphatase OtsB1
M. leprae Br4923MLBr_00414otsB24e-2134.33% (268) putative trehalose-6-phosphate phosphatase
M. abscessus ATCC 19977MAB_0578c-3e-7761.85% (249) putative trehalose phosphatase
M. marinum MMMAR_2257otsB11e-2333.99% (253) trehalose-6-phosphate phosphatase OtsB1
M. avium 104MAV_4338-5e-2236.18% (246) glycosyl hydrolase
M. smegmatis MC2 155MSMEG_6043otsB1e-9473.28% (247) trehalose-phosphatase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0921otsB28e-1934.38% (256) trehalose-6-phosphate phosphatase OtsB2

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_00414|M.leprae_Br4923          -----------MPVTIDPRRHSAALFDLDAVVTDTP--------------
MUL_0921|M.ulcerans_Agy99           -----------MSVTIDPRRH-------DAVLFDTA--------------
MAV_4338|M.avium_104                -------MGESGPVVIDPRRH-------DAVLFGVG--------------
Mb2029|M.bovis_AF2122/97            MRCGIVVNVTGPPPTIDRRYH-------DAVIVGLDNVVDKATRVHAAAW
Rv2006|M.tuberculosis_H37Rv         MRCGIVVNVTGPPPTIDRRYH-------DAVIVGLDNVVDKATRVHAAAW
MMAR_2257|M.marinum_M               MKS----------FTIDPRRH-------DGVIFVLD--------------
MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            TKFLDDYLTRRPQRTGEDHCPLTHDDYRRFLAGKPDSVADFLAARGIRLP
Rv2006|M.tuberculosis_H37Rv         TKFLDDYLTRRPQRTGEDHCPLTHDDYRRFLAGKPDGVADFLAARGIRLP
MMAR_2257|M.marinum_M               ---------------GDGH------------------------EQSIWEP
MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          ---------------------------------LDSTVTLVRQLQGIGVG
MUL_0921|M.ulcerans_Agy99           ---------------------------------LNSTQALVRQLQQARVG
MAV_4338|M.avium_104                ---------------------------------DALGSALASQLGQIGVG
Mb2029|M.bovis_AF2122/97            PGSPTDLTDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVR
Rv2006|M.tuberculosis_H37Rv         PGSPTDLTDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVR
MMAR_2257|M.marinum_M               ------------------------------------TVALARKLWQVGVG
MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          TAVFSTNRNSQGVLTATGLDHLF--------PVHVDGLASGKVTILVAAA
MUL_0921|M.ulcerans_Agy99           TATFASG----------------------------GGGHDAAIQALIESA
MAV_4338|M.avium_104                TAAIAAD-------------------------------------DPAAAA
Mb2029|M.bovis_AF2122/97            VAAHTSHRNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETA
Rv2006|M.tuberculosis_H37Rv         VAAHTSHRNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETA
MMAR_2257|M.marinum_M               TAVYSPTDESVRVLDAAGLSEPEQVSAP-----PQASRAKPYCVGLSAAA
MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          NRLMAQPGRCVVVAVDAAGITAARYGGFALVLGLVIGEDQTGHRDTLRNS
MUL_0921|M.ulcerans_Agy99           DRVGARPGRCVVITADAASVAAARDSGFALVIG----VDQAGHRDALPDH
MAV_4338|M.avium_104                DRLRVRPGRCVVVAGDPAAVEAARAAGFALVIG---LAPDGRDGDGLRAA
Mb2029|M.bovis_AF2122/97            KRLGANPGRCVVIDSCQTGLRAGRNGGFALVIA----VDAHGDAENLLSS
Rv2006|M.tuberculosis_H37Rv         KRLGANPGRCVVIDSCQTGLRAGRNGGFALVIA----VDAHGDAENLLSS
MMAR_2257|M.marinum_M               AKLGAAVQRLAVVAGMDGGVEAARECGFAFVIG----FDRDGRAEELLRR
MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          GADTVVADLGEVIVRTGDRRMSELPDALQTL-GLTDDLTARQPAVFFDFD
MUL_0921|M.ulcerans_Agy99           GADTVLADLDEVRVRAGDRHMSELPDALQAL-GRPDGLTVPRPAVFFDFD
MAV_4338|M.avium_104                GADAVIAELEQITVRTGDRRMSQLPDASQALTGGADGLAGRHPAVFFDFD
Mb2029|M.bovis_AF2122/97            GADAVVADLAAVTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFD
Rv2006|M.tuberculosis_H37Rv         GADAVVADLAAVTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFD
MMAR_2257|M.marinum_M               GADVVAADLAEVTVRTGDERLSQCPNALDSYGQVIGMVAGRQLFVCMDYD
MAB_0578c|M.abscessus_ATCC_199      -------------------MVSAQDLPVELRRALSEVARTPRLLVASDYD
MSMEG_6043|M.smegmatis_MC2_155      -----------------------MSLSGDLQRALTAVAATPHLLVTSDFD
Mvan_5313|M.vanbaalenii_PYR-1       ---------------------MSVDLPSELVSALDSAAATTRLLVTSDFD
Mflv_1458|M.gilvum_PYR-GCK          ----------------------MSALLPELESALSAAARTPRLLVASDFD
                                                                :            :  *  *:*

MLBr_00414|M.leprae_Br4923          GTLSDIVDDPDSARPVPGATEALQKLATHCP--VAILSGRDLADVIKRIG
MUL_0921|M.ulcerans_Agy99           GTLSEIVDDPDAATPTAGAVAALQQLAAQCP--VAILSGRDLADVSQRVG
MAV_4338|M.avium_104                GTLSDIVDDPDAARPVAGATAALTRLAARCP--VAVLSGRDLADVTKRVG
Mb2029|M.bovis_AF2122/97            GTLSDIVERPEAATLVDGAAEALRALAAQCP--VAVISGRDLADVRNRVK
Rv2006|M.tuberculosis_H37Rv         GTLSDIVERPEAATLVDGAAEALRALAAQCP--VAVISGRDLADVRNRVK
MMAR_2257|M.marinum_M               GTLSEIVSEPDAATLVDGAAEALAHLSTQCP--VAILSGRDLTDIRDRVG
MAB_0578c|M.abscessus_ATCC_199      GTIAPLVNNPDHARPHPESTTALRALAGLPSTTSALISGRALRDLATLSR
MSMEG_6043|M.smegmatis_MC2_155      GTLAPIVNNPADARPLADAAEALAALAELPQTASALISGRALEVLRALSG
Mvan_5313|M.vanbaalenii_PYR-1       GTLAPIVNNPADARPLPAAAQALVALADLAATTTALISGRALETLRELSS
Mflv_1458|M.gilvum_PYR-GCK          GTLAPIVNNPADARPLPGAAEALIALATLPSTAAALISGRALATLRELSS
                                    **:: :*. *  *     :. **  *:       *::*** *  :     

MLBr_00414|M.leprae_Br4923          VPG-IWYSGSHGFESTAPDGTHHQNDAAEATIPILEQAATQLRDQLGPIP
MUL_0921|M.ulcerans_Agy99           LPG-IWYAGSHGFELTAPDGTHHQNEAAAAAIPVLEQAAAQLRDRLGSIP
MAV_4338|M.avium_104                VPG-IWYAGSHGFELTAPDGSHHQNDDAAAAIPVLAQAAGRLSDELGTIP
Mb2029|M.bovis_AF2122/97            VDG-LWLAGSHGFELVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIA
Rv2006|M.tuberculosis_H37Rv         VDG-LWLAGSHGFELVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIA
MMAR_2257|M.marinum_M               VPG-IWYAGSHGFELIAPDGTHHQHEAAAAAVDVLASAAKDLRHELAQIP
MAB_0578c|M.abscessus_ATCC_199      LPSEVHLVGSHGSEFDAG----FVHAIDGDAKALLKTIATKLSAIAAEYP
MSMEG_6043|M.smegmatis_MC2_155      MPDTVHLVGSHGAEFTSG----FGHDID---TALLQRITDRLHTIASGRP
Mvan_5313|M.vanbaalenii_PYR-1       MPATVHLIGSHGAEFDSG----FAHDID---HDLLRAITDRLRAIASDKP
Mflv_1458|M.gilvum_PYR-GCK          MPDSVHLVGSHGAEFESG----FSRDID---RDLLQTITDGLDAIAAGRP
                                    :   :   **** *  :     . .         *   :  *       .

MLBr_00414|M.leprae_Br4923          GVMVEHKRFGVAVHYRNVARDRVNEVAVAVRTAGQRNALRVTTGREVIEL
MUL_0921|M.ulcerans_Agy99           GVMVEHKRFGVATHYRNAARNRVGKIAAVVRAAGQRDGLRVTTGREVIEL
MAV_4338|M.avium_104                GVVVEHKRFGVAVHYRNAARDRVGEVAAAVRAAGRHDALRVTTGREVIEL
Mb2029|M.bovis_AF2122/97            GAVVEHKRFAVAVHYRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVEL
Rv2006|M.tuberculosis_H37Rv         GAVVEHKRFAVAVHYRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVEL
MMAR_2257|M.marinum_M               GVSVEHKRFGVAVHYRNVAREHVAQVIATTHRYRREYGLRVTSGRKVVEL
MAB_0578c|M.abscessus_ATCC_199      GVAIELKPASVALHVRNASEEDADAALRQALSVANGWGAQVTEGKKVLEF
MSMEG_6043|M.smegmatis_MC2_155      GVTVETKPASVALHVRNASPEHGAAALTEARTAAAEWDAQLTEGKAVLEF
Mvan_5313|M.vanbaalenii_PYR-1       GVAVETKPASVALHVRNASPADGEAALAAAWEAAPEWEAHVTTGKAVLEF
Mflv_1458|M.gilvum_PYR-GCK          GVAVETKPASVALHVRNASPADGDAALAAAWDAARDWDAHITTGKAVLEF
                                    *. :* *  .** * **.:          .         ::* *: *:*:

MLBr_00414|M.leprae_Br4923          RPDIDWDKGKTLHWVIDRLHHAGTQVGSASLMPICLGDDITDEDAFDAVR
MUL_0921|M.ulcerans_Agy99           HPDIDWDKGKTLRWVIDHLPDQ----RAAPLVPIYLGDDITDEDAFDAVG
MAV_4338|M.avium_104                RPDLDWDKGKTLHWVIEHLRRS----GSGALTPVYLGDDITDEDAFDAVR
Mb2029|M.bovis_AF2122/97            RPDIAWDKGKALDWIGERLGPAEVG--PDLRLPIYIGDDLTDEDAFDAVR
Rv2006|M.tuberculosis_H37Rv         RPDIAWDKGKALDWIGERLGPAEVG--PDLRLPIYIGDDLTDEDAFDAVR
MMAR_2257|M.marinum_M               RPDIDWDKGAALAWIRSLIFEDSR------VLPMYVGDDLTDEDAFDALR
MAB_0578c|M.abscessus_ATCC_199      A-VIPTDKGQALDILRHQEGAT---------AAVFFGDDVTDEKAFKRLH
MSMEG_6043|M.smegmatis_MC2_155      A-VIQTDKGEAVDILRQQENAT---------AVVFFGDDVTDEKAFRRLR
Mvan_5313|M.vanbaalenii_PYR-1       A-VIDTDKGAAVDILRGECDAT---------AVVFFGDDVTDEKAFARLR
Mflv_1458|M.gilvum_PYR-GCK          A-VISTDKGEAVDILRERLQAT---------TVVFLGDDVTDEKAFVRLG
                                       :  *** ::  :                  : .***:***.**  : 

MLBr_00414|M.leprae_Br4923          HTDVGGIPIVVRHTEDGNRATAALFTLDSPMHVSEFTERLARQLSDTQR-
MUL_0921|M.ulcerans_Agy99           P---NGVAIMVRHNEDGDRATAALFALESPARVAEFTGRLASQLSTLG--
MAV_4338|M.avium_104                GGPVQGVPILVRHNDDGDRATAALFALDSPARAAEFTERLADQLERGEG-
Mb2029|M.bovis_AF2122/97            FT---GVGIVVRHNEHGDRRSAATFRLECPYTVCQFLSQLACDLQEAVQH
Rv2006|M.tuberculosis_H37Rv         FT---GVGIVVRHNEHGDRRSAATFRLECPYTVCQFLSQLACDLQEAVQH
MMAR_2257|M.marinum_M               FS---GVGIVVRHDEDGDRPTAANFTLRNPNEVRDFVRRGAGWLAHAHET
MAB_0578c|M.abscessus_ATCC_199      GP---DVGVKVGDGE-----TLAGYRIPDTESVGTALAFLLEERRTWLLG
MSMEG_6043|M.smegmatis_MC2_155      GD---DVGVKVGPGE-----SLAAYRVDSPEDVAAALDHLLAVRR----G
Mvan_5313|M.vanbaalenii_PYR-1       RS---DVGVKVGPGE-----SAAGYRIDSPDAVAAALEHLVASRK-----
Mflv_1458|M.gilvum_PYR-GCK          ES---DVGVKVGPGD-----TAAAYRVESPADVATALRHLVDTRAAQ---
                                         .: : *   :     : * : :  .  .                 

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            DDP-WTLVFHGYDPGQERLREALCAVGNGYLGSRGCAPESAESEAHYPGT
Rv2006|M.tuberculosis_H37Rv         DDP-WTLVFHGYDPGQERLREALCAVGNGYLGSRGCAPESAESEAHYPGT
MMAR_2257|M.marinum_M               QSRGWTFTFEGYDPPNEKLREALCTVGNGYFATRGAAPESKAGQVHYPGT
MAB_0578c|M.abscessus_ATCC_199      GHATPIERLTMLANSRTIALVTPTGDVTWMCHPEPDSAAVFAHLLGGPEA
MSMEG_6043|M.smegmatis_MC2_155      A-------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       -------RLA----------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          -------------------------------SPQPAP-------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            YVAGVYNQLTDHIEGCTVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELL
Rv2006|M.tuberculosis_H37Rv         YVAGVYNQLTDHIEGCTVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELL
MMAR_2257|M.marinum_M               YAGGVFNRLDDLIGGTRTAHESLVNLPNWLPLTFRIDGGDWFDVDAVTLL
MAB_0578c|M.abscessus_ATCC_199      GHFTIGPARSALPLGQKYIDSTMTVETRWASLQVTDYLAHDEVPGRTDLI
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            SYRQTFDLRRATLTRSLRFRDAGGRVTTMTQERFASMNRPNLVALQTRIE
Rv2006|M.tuberculosis_H37Rv         SYRQTFDLRRATLTRSLRFRDAGGRVTTMTQERFASMNRPNLVALQTRIE
MMAR_2257|M.marinum_M               SYRQTLDLRGAVLTRELTFRDDAGRTSSVTQHRFVSMNQAHVAALQTTIV
MAB_0578c|M.abscessus_ATCC_199      RVVTGEADAVVTFAPRPEFGQAPVQLVAEADGLRVLGTNDPIVLRAPGVT
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            SENWSGTVDFRSLVDGGVHNTLVDRYRQLSSQHLTTAEIEVLAD-SVLLR
Rv2006|M.tuberculosis_H37Rv         SENWSGTVDFRSLVDGGVHNTLVDRYRQLSSQHLTTAEIEVLAD-SVLLR
MMAR_2257|M.marinum_M               GHDWSGTIEIRSTIDGNVRNSGVERYRNLASNHLQGLQKAVLSENSVSMA
MAB_0578c|M.abscessus_ATCC_199      WTIGADDQTATATISPANGPIILELRCGTEDLGENPTSEPELRERAESYW
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            TQTSQSGIAIAVAARSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQ
Rv2006|M.tuberculosis_H37Rv         TQTSQSGIAIAVAARSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQ
MMAR_2257|M.marinum_M               VETTQSKIPVAVAARTSLWRADEPVAATYRLLDEEFEIGHEIFTEAKLGQ
MAB_0578c|M.abscessus_ATCC_199      RDWAQTLTLPERKPGLMKRSALTLRGLVHAESGAILAAATTSLPEDIGGI
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            SVTLEKVATIFTSRDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLW
Rv2006|M.tuberculosis_H37Rv         SVTLEKVATIFTSRDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLW
MMAR_2257|M.marinum_M               PLTVEKIVTLVSGLDVATSHPAIGAERRLGRQGRFAEICDAHRIAWSHLW
MAB_0578c|M.abscessus_ATCC_199      RNWDYRYCWLRDASMTASALVALGSLSEAEGLLGWLHRVLEHLPGPDRLH
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            ERCAIDLTGNTEELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYR
Rv2006|M.tuberculosis_H37Rv         ERCAIDLTGNTEELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYR
MMAR_2257|M.marinum_M               ERLSIEFSNHTEELRVLRLHLLHLLQTVSYNSADLDVGVPARGLHGEAYR
MAB_0578c|M.abscessus_ATCC_199      PLYTLAGTALPPEAVIDSLPGYAGSRPVRVGNAANSQ-------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            GHVFWDALFVAPVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMY
Rv2006|M.tuberculosis_H37Rv         GHVFWDALFVAPVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMY
MMAR_2257|M.marinum_M               GHIFWDELFIFPVLNLRLPAVTRSLLLYRYRRLLEAQRAAKLAGYRGAMY
MAB_0578c|M.abscessus_ATCC_199      ---VQLDVFGPVVELIHDLSHARKHLGHSDPLTDADWNLVSDMVLAVERR
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            PWQSGSDGSEVSQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVT
Rv2006|M.tuberculosis_H37Rv         PWQSGSDGSEVSQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVT
MMAR_2257|M.marinum_M               PWQSGSDGREESPEQHLNPRSGRWIPDASHRAHHIGIAVAYNVWQFYQVT
MAB_0578c|M.abscessus_ATCC_199      WYEPDHGIWEIRGNPRHHVYSKVMCWVTVDRAVKLAEEFERAAPSSWAAL
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            GDRQYLVDCGAELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYP
Rv2006|M.tuberculosis_H37Rv         GDRQYLVDCGAELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYP
MMAR_2257|M.marinum_M               GDLAFMIDYGTEMMAEIARFWVSRATYDAERDRYHIKGVIGPDEFHSGYP
MAB_0578c|M.abscessus_ATCC_199      RDEIAAEVIEKGWNESVNSYTAAYDGTDLDAATLYIGLSGLIDPTDPRFT
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            GNEYDGIDNNAYTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQER
Rv2006|M.tuberculosis_H37Rv         GNEYDGIDNNAYTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQER
MMAR_2257|M.marinum_M               DRPYDGVDDNAYTNVMAAWVILRAIDALLLMPLPNRLDLYEKLALTEEEL
MAB_0578c|M.abscessus_ATCC_199      ATVIATEAELRSGATVYRYHRDDCLPGGEGGFHLCAAWLVEAYLLIGARS
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            DQWDDVSRRMFVPFHDGVISQFEGYSELAELDWDHYRHRYGNIQRLDRIL
Rv2006|M.tuberculosis_H37Rv         DQWDDVSRRMFVPFHDGVISQFEGYSELAELDWDHYRHRYGNIQRLDRIL
MMAR_2257|M.marinum_M               AQWDHVSRRMFVPFHDGVISQFDGYEQLAELDWDAYRQRYGNIQRLDRIL
MAB_0578c|M.abscessus_ATCC_199      QAELLFDQLVKATGPTGLLSEEYDPVAERSLGNHPQAYSHIGLLRCAALL
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            EAEGDSVNNYQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTV
Rv2006|M.tuberculosis_H37Rv         EAEGDSVNNYQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTV
MMAR_2257|M.marinum_M               EAEDDDVNRYRASKQADALMLLYLLSADELGELLDRLGYHMERDQIPEMV
MAB_0578c|M.abscessus_ATCC_199      S-------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            DYYLARTSDGSTLSAVVHAWVLARANRSNAMEYFRQVLRSDIADVQGGTT
Rv2006|M.tuberculosis_H37Rv         DYYLARTSDGSTLSAVVHAWVLARANRSNAMEYFRQVLRSDIADVQGGTT
MMAR_2257|M.marinum_M               DYYMARTSHGSTLSAAVHGWVLARANRDRALEFFQQVLESDVADIQGGTT
MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
Mb2029|M.bovis_AF2122/97            QEGIHLAAMAGSIDLPQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYR
Rv2006|M.tuberculosis_H37Rv         QEGIHLAAMAGSIDLLQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYR
MMAR_2257|M.marinum_M               AEGVHLAAMAGSVDFVQRCFTGLEIRADRIVLSPHWPEYLGALGFPIHYR
MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

MLBr_00414|M.leprae_Br4923          ------------------------------------------------
MUL_0921|M.ulcerans_Agy99           ------------------------------------------------
MAV_4338|M.avium_104                ------------------------------------------------
Mb2029|M.bovis_AF2122/97            RHQLSLRISGRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR
Rv2006|M.tuberculosis_H37Rv         RHQLSLRISGRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR
MMAR_2257|M.marinum_M               GNHLHLRVSGKGAEISVEPRDVPPVEVECHGRVERLLPGSTVRFS---
MAB_0578c|M.abscessus_ATCC_199      ------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      ------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       ------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          ------------------------------------------------