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VSVDLPSELVSALDSAAATTRLLVTSDFDGTLAPIVNNPADARPLPAAAQALVALADLAATTTALISGRA LETLRELSSMPATVHLIGSHGAEFDSGFAHDIDHDLLRAITDRLRAIASDKPGVAVETKPASVALHVRNA SPADGEAALAAAWEAAPEWEAHVTTGKAVLEFAVIDTDKGAAVDILRGECDATAVVFFGDDVTDEKAFAR LRRSDVGVKVGPGESAAGYRIDSPDAVAAALEHLVASRKRLA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5313 | - | - | 100% (252) | HAD family hydrolase |
M. vanbaalenii PYR-1 | Mvan_4107 | - | 3e-20 | 30.56% (252) | HAD family hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2029 | otsB1 | 7e-20 | 34.73% (262) | trehalose-6-phosphate phosphatase OtsB1 |
M. gilvum PYR-GCK | Mflv_1458 | - | 1e-100 | 75.81% (248) | HAD family hydrolase |
M. tuberculosis H37Rv | Rv2006 | otsB1 | 7e-20 | 34.73% (262) | trehalose-6-phosphate phosphatase OtsB1 |
M. leprae Br4923 | MLBr_00414 | otsB2 | 4e-21 | 34.33% (268) | putative trehalose-6-phosphate phosphatase |
M. abscessus ATCC 19977 | MAB_0578c | - | 3e-77 | 61.85% (249) | putative trehalose phosphatase |
M. marinum M | MMAR_2257 | otsB1 | 1e-23 | 33.99% (253) | trehalose-6-phosphate phosphatase OtsB1 |
M. avium 104 | MAV_4338 | - | 5e-22 | 36.18% (246) | glycosyl hydrolase |
M. smegmatis MC2 155 | MSMEG_6043 | otsB | 1e-94 | 73.28% (247) | trehalose-phosphatase |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_0921 | otsB2 | 8e-19 | 34.38% (256) | trehalose-6-phosphate phosphatase OtsB2 |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_00414|M.leprae_Br4923 -----------MPVTIDPRRHSAALFDLDAVVTDTP-------------- MUL_0921|M.ulcerans_Agy99 -----------MSVTIDPRRH-------DAVLFDTA-------------- MAV_4338|M.avium_104 -------MGESGPVVIDPRRH-------DAVLFGVG-------------- Mb2029|M.bovis_AF2122/97 MRCGIVVNVTGPPPTIDRRYH-------DAVIVGLDNVVDKATRVHAAAW Rv2006|M.tuberculosis_H37Rv MRCGIVVNVTGPPPTIDRRYH-------DAVIVGLDNVVDKATRVHAAAW MMAR_2257|M.marinum_M MKS----------FTIDPRRH-------DGVIFVLD-------------- MAB_0578c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 TKFLDDYLTRRPQRTGEDHCPLTHDDYRRFLAGKPDSVADFLAARGIRLP Rv2006|M.tuberculosis_H37Rv TKFLDDYLTRRPQRTGEDHCPLTHDDYRRFLAGKPDGVADFLAARGIRLP MMAR_2257|M.marinum_M ---------------GDGH------------------------EQSIWEP MAB_0578c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 ---------------------------------LDSTVTLVRQLQGIGVG MUL_0921|M.ulcerans_Agy99 ---------------------------------LNSTQALVRQLQQARVG MAV_4338|M.avium_104 ---------------------------------DALGSALASQLGQIGVG Mb2029|M.bovis_AF2122/97 PGSPTDLTDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVR Rv2006|M.tuberculosis_H37Rv PGSPTDLTDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVR MMAR_2257|M.marinum_M ------------------------------------TVALARKLWQVGVG MAB_0578c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 TAVFSTNRNSQGVLTATGLDHLF--------PVHVDGLASGKVTILVAAA MUL_0921|M.ulcerans_Agy99 TATFASG----------------------------GGGHDAAIQALIESA MAV_4338|M.avium_104 TAAIAAD-------------------------------------DPAAAA Mb2029|M.bovis_AF2122/97 VAAHTSHRNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETA Rv2006|M.tuberculosis_H37Rv VAAHTSHRNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETA MMAR_2257|M.marinum_M TAVYSPTDESVRVLDAAGLSEPEQVSAP-----PQASRAKPYCVGLSAAA MAB_0578c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 NRLMAQPGRCVVVAVDAAGITAARYGGFALVLGLVIGEDQTGHRDTLRNS MUL_0921|M.ulcerans_Agy99 DRVGARPGRCVVITADAASVAAARDSGFALVIG----VDQAGHRDALPDH MAV_4338|M.avium_104 DRLRVRPGRCVVVAGDPAAVEAARAAGFALVIG---LAPDGRDGDGLRAA Mb2029|M.bovis_AF2122/97 KRLGANPGRCVVIDSCQTGLRAGRNGGFALVIA----VDAHGDAENLLSS Rv2006|M.tuberculosis_H37Rv KRLGANPGRCVVIDSCQTGLRAGRNGGFALVIA----VDAHGDAENLLSS MMAR_2257|M.marinum_M AKLGAAVQRLAVVAGMDGGVEAARECGFAFVIG----FDRDGRAEELLRR MAB_0578c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 GADTVVADLGEVIVRTGDRRMSELPDALQTL-GLTDDLTARQPAVFFDFD MUL_0921|M.ulcerans_Agy99 GADTVLADLDEVRVRAGDRHMSELPDALQAL-GRPDGLTVPRPAVFFDFD MAV_4338|M.avium_104 GADAVIAELEQITVRTGDRRMSQLPDASQALTGGADGLAGRHPAVFFDFD Mb2029|M.bovis_AF2122/97 GADAVVADLAAVTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFD Rv2006|M.tuberculosis_H37Rv GADAVVADLAAVTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFD MMAR_2257|M.marinum_M GADVVAADLAEVTVRTGDERLSQCPNALDSYGQVIGMVAGRQLFVCMDYD MAB_0578c|M.abscessus_ATCC_199 -------------------MVSAQDLPVELRRALSEVARTPRLLVASDYD MSMEG_6043|M.smegmatis_MC2_155 -----------------------MSLSGDLQRALTAVAATPHLLVTSDFD Mvan_5313|M.vanbaalenii_PYR-1 ---------------------MSVDLPSELVSALDSAAATTRLLVTSDFD Mflv_1458|M.gilvum_PYR-GCK ----------------------MSALLPELESALSAAARTPRLLVASDFD : : * *:* MLBr_00414|M.leprae_Br4923 GTLSDIVDDPDSARPVPGATEALQKLATHCP--VAILSGRDLADVIKRIG MUL_0921|M.ulcerans_Agy99 GTLSEIVDDPDAATPTAGAVAALQQLAAQCP--VAILSGRDLADVSQRVG MAV_4338|M.avium_104 GTLSDIVDDPDAARPVAGATAALTRLAARCP--VAVLSGRDLADVTKRVG Mb2029|M.bovis_AF2122/97 GTLSDIVERPEAATLVDGAAEALRALAAQCP--VAVISGRDLADVRNRVK Rv2006|M.tuberculosis_H37Rv GTLSDIVERPEAATLVDGAAEALRALAAQCP--VAVISGRDLADVRNRVK MMAR_2257|M.marinum_M GTLSEIVSEPDAATLVDGAAEALAHLSTQCP--VAILSGRDLTDIRDRVG MAB_0578c|M.abscessus_ATCC_199 GTIAPLVNNPDHARPHPESTTALRALAGLPSTTSALISGRALRDLATLSR MSMEG_6043|M.smegmatis_MC2_155 GTLAPIVNNPADARPLADAAEALAALAELPQTASALISGRALEVLRALSG Mvan_5313|M.vanbaalenii_PYR-1 GTLAPIVNNPADARPLPAAAQALVALADLAATTTALISGRALETLRELSS Mflv_1458|M.gilvum_PYR-GCK GTLAPIVNNPADARPLPGAAEALIALATLPSTAAALISGRALATLRELSS **:: :*. * * :. ** *: *::*** * : MLBr_00414|M.leprae_Br4923 VPG-IWYSGSHGFESTAPDGTHHQNDAAEATIPILEQAATQLRDQLGPIP MUL_0921|M.ulcerans_Agy99 LPG-IWYAGSHGFELTAPDGTHHQNEAAAAAIPVLEQAAAQLRDRLGSIP MAV_4338|M.avium_104 VPG-IWYAGSHGFELTAPDGSHHQNDDAAAAIPVLAQAAGRLSDELGTIP Mb2029|M.bovis_AF2122/97 VDG-LWLAGSHGFELVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIA Rv2006|M.tuberculosis_H37Rv VDG-LWLAGSHGFELVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIA MMAR_2257|M.marinum_M VPG-IWYAGSHGFELIAPDGTHHQHEAAAAAVDVLASAAKDLRHELAQIP MAB_0578c|M.abscessus_ATCC_199 LPSEVHLVGSHGSEFDAG----FVHAIDGDAKALLKTIATKLSAIAAEYP MSMEG_6043|M.smegmatis_MC2_155 MPDTVHLVGSHGAEFTSG----FGHDID---TALLQRITDRLHTIASGRP Mvan_5313|M.vanbaalenii_PYR-1 MPATVHLIGSHGAEFDSG----FAHDID---HDLLRAITDRLRAIASDKP Mflv_1458|M.gilvum_PYR-GCK MPDSVHLVGSHGAEFESG----FSRDID---RDLLQTITDGLDAIAAGRP : : **** * : . . * : * . MLBr_00414|M.leprae_Br4923 GVMVEHKRFGVAVHYRNVARDRVNEVAVAVRTAGQRNALRVTTGREVIEL MUL_0921|M.ulcerans_Agy99 GVMVEHKRFGVATHYRNAARNRVGKIAAVVRAAGQRDGLRVTTGREVIEL MAV_4338|M.avium_104 GVVVEHKRFGVAVHYRNAARDRVGEVAAAVRAAGRHDALRVTTGREVIEL Mb2029|M.bovis_AF2122/97 GAVVEHKRFAVAVHYRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVEL Rv2006|M.tuberculosis_H37Rv GAVVEHKRFAVAVHYRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVEL MMAR_2257|M.marinum_M GVSVEHKRFGVAVHYRNVAREHVAQVIATTHRYRREYGLRVTSGRKVVEL MAB_0578c|M.abscessus_ATCC_199 GVAIELKPASVALHVRNASEEDADAALRQALSVANGWGAQVTEGKKVLEF MSMEG_6043|M.smegmatis_MC2_155 GVTVETKPASVALHVRNASPEHGAAALTEARTAAAEWDAQLTEGKAVLEF Mvan_5313|M.vanbaalenii_PYR-1 GVAVETKPASVALHVRNASPADGEAALAAAWEAAPEWEAHVTTGKAVLEF Mflv_1458|M.gilvum_PYR-GCK GVAVETKPASVALHVRNASPADGDAALAAAWDAARDWDAHITTGKAVLEF *. :* * .** * **.: . ::* *: *:*: MLBr_00414|M.leprae_Br4923 RPDIDWDKGKTLHWVIDRLHHAGTQVGSASLMPICLGDDITDEDAFDAVR MUL_0921|M.ulcerans_Agy99 HPDIDWDKGKTLRWVIDHLPDQ----RAAPLVPIYLGDDITDEDAFDAVG MAV_4338|M.avium_104 RPDLDWDKGKTLHWVIEHLRRS----GSGALTPVYLGDDITDEDAFDAVR Mb2029|M.bovis_AF2122/97 RPDIAWDKGKALDWIGERLGPAEVG--PDLRLPIYIGDDLTDEDAFDAVR Rv2006|M.tuberculosis_H37Rv RPDIAWDKGKALDWIGERLGPAEVG--PDLRLPIYIGDDLTDEDAFDAVR MMAR_2257|M.marinum_M RPDIDWDKGAALAWIRSLIFEDSR------VLPMYVGDDLTDEDAFDALR MAB_0578c|M.abscessus_ATCC_199 A-VIPTDKGQALDILRHQEGAT---------AAVFFGDDVTDEKAFKRLH MSMEG_6043|M.smegmatis_MC2_155 A-VIQTDKGEAVDILRQQENAT---------AVVFFGDDVTDEKAFRRLR Mvan_5313|M.vanbaalenii_PYR-1 A-VIDTDKGAAVDILRGECDAT---------AVVFFGDDVTDEKAFARLR Mflv_1458|M.gilvum_PYR-GCK A-VISTDKGEAVDILRERLQAT---------TVVFLGDDVTDEKAFVRLG : *** :: : : .***:***.** : MLBr_00414|M.leprae_Br4923 HTDVGGIPIVVRHTEDGNRATAALFTLDSPMHVSEFTERLARQLSDTQR- MUL_0921|M.ulcerans_Agy99 P---NGVAIMVRHNEDGDRATAALFALESPARVAEFTGRLASQLSTLG-- MAV_4338|M.avium_104 GGPVQGVPILVRHNDDGDRATAALFALDSPARAAEFTERLADQLERGEG- Mb2029|M.bovis_AF2122/97 FT---GVGIVVRHNEHGDRRSAATFRLECPYTVCQFLSQLACDLQEAVQH Rv2006|M.tuberculosis_H37Rv FT---GVGIVVRHNEHGDRRSAATFRLECPYTVCQFLSQLACDLQEAVQH MMAR_2257|M.marinum_M FS---GVGIVVRHDEDGDRPTAANFTLRNPNEVRDFVRRGAGWLAHAHET MAB_0578c|M.abscessus_ATCC_199 GP---DVGVKVGDGE-----TLAGYRIPDTESVGTALAFLLEERRTWLLG MSMEG_6043|M.smegmatis_MC2_155 GD---DVGVKVGPGE-----SLAAYRVDSPEDVAAALDHLLAVRR----G Mvan_5313|M.vanbaalenii_PYR-1 RS---DVGVKVGPGE-----SAAGYRIDSPDAVAAALEHLVASRK----- Mflv_1458|M.gilvum_PYR-GCK ES---DVGVKVGPGD-----TAAAYRVESPADVATALRHLVDTRAAQ--- .: : * : : * : : . . MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 DDP-WTLVFHGYDPGQERLREALCAVGNGYLGSRGCAPESAESEAHYPGT Rv2006|M.tuberculosis_H37Rv DDP-WTLVFHGYDPGQERLREALCAVGNGYLGSRGCAPESAESEAHYPGT MMAR_2257|M.marinum_M QSRGWTFTFEGYDPPNEKLREALCTVGNGYFATRGAAPESKAGQVHYPGT MAB_0578c|M.abscessus_ATCC_199 GHATPIERLTMLANSRTIALVTPTGDVTWMCHPEPDSAAVFAHLLGGPEA MSMEG_6043|M.smegmatis_MC2_155 A------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------RLA---------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------SPQPAP------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 YVAGVYNQLTDHIEGCTVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELL Rv2006|M.tuberculosis_H37Rv YVAGVYNQLTDHIEGCTVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELL MMAR_2257|M.marinum_M YAGGVFNRLDDLIGGTRTAHESLVNLPNWLPLTFRIDGGDWFDVDAVTLL MAB_0578c|M.abscessus_ATCC_199 GHFTIGPARSALPLGQKYIDSTMTVETRWASLQVTDYLAHDEVPGRTDLI MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 SYRQTFDLRRATLTRSLRFRDAGGRVTTMTQERFASMNRPNLVALQTRIE Rv2006|M.tuberculosis_H37Rv SYRQTFDLRRATLTRSLRFRDAGGRVTTMTQERFASMNRPNLVALQTRIE MMAR_2257|M.marinum_M SYRQTLDLRGAVLTRELTFRDDAGRTSSVTQHRFVSMNQAHVAALQTTIV MAB_0578c|M.abscessus_ATCC_199 RVVTGEADAVVTFAPRPEFGQAPVQLVAEADGLRVLGTNDPIVLRAPGVT MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 SENWSGTVDFRSLVDGGVHNTLVDRYRQLSSQHLTTAEIEVLAD-SVLLR Rv2006|M.tuberculosis_H37Rv SENWSGTVDFRSLVDGGVHNTLVDRYRQLSSQHLTTAEIEVLAD-SVLLR MMAR_2257|M.marinum_M GHDWSGTIEIRSTIDGNVRNSGVERYRNLASNHLQGLQKAVLSENSVSMA MAB_0578c|M.abscessus_ATCC_199 WTIGADDQTATATISPANGPIILELRCGTEDLGENPTSEPELRERAESYW MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 TQTSQSGIAIAVAARSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQ Rv2006|M.tuberculosis_H37Rv TQTSQSGIAIAVAARSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQ MMAR_2257|M.marinum_M VETTQSKIPVAVAARTSLWRADEPVAATYRLLDEEFEIGHEIFTEAKLGQ MAB_0578c|M.abscessus_ATCC_199 RDWAQTLTLPERKPGLMKRSALTLRGLVHAESGAILAAATTSLPEDIGGI MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 SVTLEKVATIFTSRDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLW Rv2006|M.tuberculosis_H37Rv SVTLEKVATIFTSRDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLW MMAR_2257|M.marinum_M PLTVEKIVTLVSGLDVATSHPAIGAERRLGRQGRFAEICDAHRIAWSHLW MAB_0578c|M.abscessus_ATCC_199 RNWDYRYCWLRDASMTASALVALGSLSEAEGLLGWLHRVLEHLPGPDRLH MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 ERCAIDLTGNTEELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYR Rv2006|M.tuberculosis_H37Rv ERCAIDLTGNTEELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYR MMAR_2257|M.marinum_M ERLSIEFSNHTEELRVLRLHLLHLLQTVSYNSADLDVGVPARGLHGEAYR MAB_0578c|M.abscessus_ATCC_199 PLYTLAGTALPPEAVIDSLPGYAGSRPVRVGNAANSQ------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 GHVFWDALFVAPVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMY Rv2006|M.tuberculosis_H37Rv GHVFWDALFVAPVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMY MMAR_2257|M.marinum_M GHIFWDELFIFPVLNLRLPAVTRSLLLYRYRRLLEAQRAAKLAGYRGAMY MAB_0578c|M.abscessus_ATCC_199 ---VQLDVFGPVVELIHDLSHARKHLGHSDPLTDADWNLVSDMVLAVERR MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 PWQSGSDGSEVSQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVT Rv2006|M.tuberculosis_H37Rv PWQSGSDGSEVSQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVT MMAR_2257|M.marinum_M PWQSGSDGREESPEQHLNPRSGRWIPDASHRAHHIGIAVAYNVWQFYQVT MAB_0578c|M.abscessus_ATCC_199 WYEPDHGIWEIRGNPRHHVYSKVMCWVTVDRAVKLAEEFERAAPSSWAAL MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 GDRQYLVDCGAELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYP Rv2006|M.tuberculosis_H37Rv GDRQYLVDCGAELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYP MMAR_2257|M.marinum_M GDLAFMIDYGTEMMAEIARFWVSRATYDAERDRYHIKGVIGPDEFHSGYP MAB_0578c|M.abscessus_ATCC_199 RDEIAAEVIEKGWNESVNSYTAAYDGTDLDAATLYIGLSGLIDPTDPRFT MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 GNEYDGIDNNAYTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQER Rv2006|M.tuberculosis_H37Rv GNEYDGIDNNAYTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQER MMAR_2257|M.marinum_M DRPYDGVDDNAYTNVMAAWVILRAIDALLLMPLPNRLDLYEKLALTEEEL MAB_0578c|M.abscessus_ATCC_199 ATVIATEAELRSGATVYRYHRDDCLPGGEGGFHLCAAWLVEAYLLIGARS MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 DQWDDVSRRMFVPFHDGVISQFEGYSELAELDWDHYRHRYGNIQRLDRIL Rv2006|M.tuberculosis_H37Rv DQWDDVSRRMFVPFHDGVISQFEGYSELAELDWDHYRHRYGNIQRLDRIL MMAR_2257|M.marinum_M AQWDHVSRRMFVPFHDGVISQFDGYEQLAELDWDAYRQRYGNIQRLDRIL MAB_0578c|M.abscessus_ATCC_199 QAELLFDQLVKATGPTGLLSEEYDPVAERSLGNHPQAYSHIGLLRCAALL MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 EAEGDSVNNYQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTV Rv2006|M.tuberculosis_H37Rv EAEGDSVNNYQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTV MMAR_2257|M.marinum_M EAEDDDVNRYRASKQADALMLLYLLSADELGELLDRLGYHMERDQIPEMV MAB_0578c|M.abscessus_ATCC_199 S------------------------------------------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 DYYLARTSDGSTLSAVVHAWVLARANRSNAMEYFRQVLRSDIADVQGGTT Rv2006|M.tuberculosis_H37Rv DYYLARTSDGSTLSAVVHAWVLARANRSNAMEYFRQVLRSDIADVQGGTT MMAR_2257|M.marinum_M DYYMARTSHGSTLSAAVHGWVLARANRDRALEFFQQVLESDVADIQGGTT MAB_0578c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 -------------------------------------------------- MUL_0921|M.ulcerans_Agy99 -------------------------------------------------- MAV_4338|M.avium_104 -------------------------------------------------- Mb2029|M.bovis_AF2122/97 QEGIHLAAMAGSIDLPQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYR Rv2006|M.tuberculosis_H37Rv QEGIHLAAMAGSIDLLQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYR MMAR_2257|M.marinum_M AEGVHLAAMAGSVDFVQRCFTGLEIRADRIVLSPHWPEYLGALGFPIHYR MAB_0578c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6043|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_5313|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1458|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00414|M.leprae_Br4923 ------------------------------------------------ MUL_0921|M.ulcerans_Agy99 ------------------------------------------------ MAV_4338|M.avium_104 ------------------------------------------------ Mb2029|M.bovis_AF2122/97 RHQLSLRISGRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR Rv2006|M.tuberculosis_H37Rv RHQLSLRISGRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR MMAR_2257|M.marinum_M GNHLHLRVSGKGAEISVEPRDVPPVEVECHGRVERLLPGSTVRFS--- MAB_0578c|M.abscessus_ATCC_199 ------------------------------------------------ MSMEG_6043|M.smegmatis_MC2_155 ------------------------------------------------ Mvan_5313|M.vanbaalenii_PYR-1 ------------------------------------------------ Mflv_1458|M.gilvum_PYR-GCK ------------------------------------------------