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M. gilvum PYR-GCK Mflv_1458 (-)

annotation: HAD family hydrolase
coordinates: 1519389 - 1520159
length: 256

SALLPELESALSAAARTPRLLVASDFDGTLAPIVNNPADARPLPGAAEALIALATLPSTAAALISGRALA
TLRELSSMPDSVHLVGSHGAEFESGFSRDIDRDLLQTITDGLDAIAAGRPGVAVETKPASVALHVRNASP
ADGDAALAAAWDAARDWDAHITTGKAVLEFAVISTDKGEAVDILRERLQATTVVFLGDDVTDEKAFVRLG
ESDVGVKVGPGDTAAAYRVESPADVATALRHLVDTRAAQSPQPAP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1458--100% (256)HAD family hydrolase
M. gilvum PYR-GCKMflv_4989-5e-2232.68% (254) HAD family hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2029otsB13e-2434.83% (267) trehalose-6-phosphate phosphatase OtsB1
M. tuberculosis H37RvRv2006otsB13e-2434.83% (267) trehalose-6-phosphate phosphatase OtsB1
M. leprae Br4923MLBr_00414otsB26e-2232.49% (277) putative trehalose-6-phosphate phosphatase
M. abscessus ATCC 19977MAB_0578c-2e-7663.11% (244) putative trehalose phosphatase
M. marinum MMMAR_1156otsB26e-2436.58% (257) trehalose-6-phosphate phosphatase OtsB2
M. avium 104MAV_4338-2e-2336.80% (269) glycosyl hydrolase
M. smegmatis MC2 155MSMEG_6043otsB5e-9373.06% (245) trehalose-phosphatase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0921otsB22e-2336.19% (257) trehalose-6-phosphate phosphatase OtsB2
M. vanbaalenii PYR-1Mvan_5313-1e-10075.81% (248) HAD family hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            MRCGIVVNVTGPPPTIDRRYHDAVIVGLDNVVDKATRVHAAAWTKFLDDY
Rv2006|M.tuberculosis_H37Rv         MRCGIVVNVTGPPPTIDRRYHDAVIVGLDNVVDKATRVHAAAWTKFLDDY
MMAR_1156|M.marinum_M               -----------MSVTIDPRRH-------DAVLFDTA--------------
MUL_0921|M.ulcerans_Agy99           -----------MSVTIDPRRH-------DAVLFDTA--------------
MLBr_00414|M.leprae_Br4923          -----------MPVTIDPRRHSAALFDLDAVVTDTP--------------
MAV_4338|M.avium_104                -------MGESGPVVIDPRRH-------DAVLFGVG--------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            LTRRPQRTGEDHCPLTHDDYRRFLAGKPDSVADFLAARGIRLPPGSPTDL
Rv2006|M.tuberculosis_H37Rv         LTRRPQRTGEDHCPLTHDDYRRFLAGKPDGVADFLAARGIRLPPGSPTDL
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            TDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVRVAAHTSH
Rv2006|M.tuberculosis_H37Rv         TDDTVYGLQNLERQTFLQLLNTGVPEGKSIASFARRLQVAGVRVAAHTSH
MMAR_1156|M.marinum_M               --------------------------LNSTQALVRQLQQARVGTATFASG
MUL_0921|M.ulcerans_Agy99           --------------------------LNSTQALVRQLQQARVGTATFASG
MLBr_00414|M.leprae_Br4923          --------------------------LDSTVTLVRQLQGIGVGTAVFSTN
MAV_4338|M.avium_104                --------------------------DALGSALASQLGQIGVGTAAIAAD
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            RNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETAKRLGANP
Rv2006|M.tuberculosis_H37Rv         RNYGHTLDATGLAEVFAVFVDGAVTAELGLPAEPNPAGLIETAKRLGANP
MMAR_1156|M.marinum_M               --------------------GGGHDAAI--------QALTESADRVGARP
MUL_0921|M.ulcerans_Agy99           --------------------GGGHDAAI--------QALIESADRVGARP
MLBr_00414|M.leprae_Br4923          RNSQGVLTATGLDHLFPVHVDGLASGKV--------TILVAAANRLMAQP
MAV_4338|M.avium_104                -------------------------------------DPAAAADRLRVRP
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            GRCVVIDSCQTGLRAGRNGGFALVIA----VDAHGDAENLLSSGADAVVA
Rv2006|M.tuberculosis_H37Rv         GRCVVIDSCQTGLRAGRNGGFALVIA----VDAHGDAENLLSSGADAVVA
MMAR_1156|M.marinum_M               GRCVVITADAASVAAARDSGFALVIG----VDQAGHRDALPDHGADTVLA
MUL_0921|M.ulcerans_Agy99           GRCVVITADAASVAAARDSGFALVIG----VDQAGHRDALPDHGADTVLA
MLBr_00414|M.leprae_Br4923          GRCVVVAVDAAGITAARYGGFALVLGLVIGEDQTGHRDTLRNSGADTVVA
MAV_4338|M.avium_104                GRCVVVAGDPAAVEAARAAGFALVIG---LAPDGRDGDGLRAAGADAVIA
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      ------MVSAQDLPVELRRALSEVARTPRLLVAS------DYDGTIAPLV
MSMEG_6043|M.smegmatis_MC2_155      ----------MSLSGDLQRALTAVAATPHLLVTS------DFDGTLAPIV
Mvan_5313|M.vanbaalenii_PYR-1       --------MSVDLPSELVSALDSAAATTRLLVTS------DFDGTLAPIV
Mflv_1458|M.gilvum_PYR-GCK          ---------MSALLPELESALSAAARTPRLLVAS------DFDGTLAPIV
Mb2029|M.bovis_AF2122/97            DLAAVTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFDGTLSDIV
Rv2006|M.tuberculosis_H37Rv         DLAAVTVGSGDAAISTIPDALQVYSQLKRLLTGRRPAVFLDFDGTLSDIV
MMAR_1156|M.marinum_M               DLDEVRVRAGDRHMSELPDALQAL-GRPDGLTVPRPAVFFDFDGTLSEIV
MUL_0921|M.ulcerans_Agy99           DLDEVRVRAGDRHMSELPDALQAL-GRPDGLTVPRPAVFFDFDGTLSEIV
MLBr_00414|M.leprae_Br4923          DLGEVIVRTGDRRMSELPDALQTL-GLTDDLTARQPAVFFDFDGTLSDIV
MAV_4338|M.avium_104                ELEQITVRTGDRRMSQLPDASQALTGGADGLAGRHPAVFFDFDGTLSDIV
                                                    :  *          *.        *:***:: :*

MAB_0578c|M.abscessus_ATCC_199      NNPDHARPHPESTTALRALAGLPSTTSALISGRALRDLATLSRLPSEVHL
MSMEG_6043|M.smegmatis_MC2_155      NNPADARPLADAAEALAALAELPQTASALISGRALEVLRALSGMPDTVHL
Mvan_5313|M.vanbaalenii_PYR-1       NNPADARPLPAAAQALVALADLAATTTALISGRALETLRELSSMPATVHL
Mflv_1458|M.gilvum_PYR-GCK          NNPADARPLPGAAEALIALATLPSTAAALISGRALATLRELSSMPDSVHL
Mb2029|M.bovis_AF2122/97            ERPEAATLVDGAAEALRALAAQCP--VAVISGRDLADVRNRVKVDG-LWL
Rv2006|M.tuberculosis_H37Rv         ERPEAATLVDGAAEALRALAAQCP--VAVISGRDLADVRNRVKVDG-LWL
MMAR_1156|M.marinum_M               DDPDAATPTAGAVAALQQLAAQCP--VAILSGRDLADVSQRVGLPG-IWY
MUL_0921|M.ulcerans_Agy99           DDPDAATPTAGAVAALQQLAAQCP--VAILSGRDLADVSQRVGLPG-IWY
MLBr_00414|M.leprae_Br4923          DDPDSARPVPGATEALQKLATHCP--VAILSGRDLADVIKRIGVPG-IWY
MAV_4338|M.avium_104                DDPDAARPVAGATAALTRLAARCP--VAVLSGRDLADVTKRVGVPG-IWY
                                    : *  *     :. **  **       *::*** *  :     :   :  

MAB_0578c|M.abscessus_ATCC_199      VGSHGSEFDAG----FVHAIDGDAKALLKTIATKLSAIAAEYPGVAIELK
MSMEG_6043|M.smegmatis_MC2_155      VGSHGAEFTSG----FGHDID---TALLQRITDRLHTIASGRPGVTVETK
Mvan_5313|M.vanbaalenii_PYR-1       IGSHGAEFDSG----FAHDID---HDLLRAITDRLRAIASDKPGVAVETK
Mflv_1458|M.gilvum_PYR-GCK          VGSHGAEFESG----FSRDID---RDLLQTITDGLDAIAAGRPGVAVETK
Mb2029|M.bovis_AF2122/97            AGSHGFELVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIAGAVVEHK
Rv2006|M.tuberculosis_H37Rv         AGSHGFELVAPDGSHHQNAAATAAIDGLAEAAAQLADALREIAGAVVEHK
MMAR_1156|M.marinum_M               AGSHGFELTAPDGTHHQNEAAAAAIPVLEQAAAQLRDRLGSIPGVMVEHK
MUL_0921|M.ulcerans_Agy99           AGSHGFELTAPDGTHHQNEAAAAAIPVLEQAAAQLRDRLGSIPGVMVEHK
MLBr_00414|M.leprae_Br4923          SGSHGFESTAPDGTHHQNDAAEATIPILEQAATQLRDQLGPIPGVMVEHK
MAV_4338|M.avium_104                AGSHGFELTAPDGSHHQNDDAAAAIPVLAQAAGRLSDELGTIPGVVVEHK
                                     **** *  :     . .         *   :  *       .*. :* *

MAB_0578c|M.abscessus_ATCC_199      PASVALHVRNASEEDADAALRQALSVANGWGAQVTEGKKVLEFA-VIPTD
MSMEG_6043|M.smegmatis_MC2_155      PASVALHVRNASPEHGAAALTEARTAAAEWDAQLTEGKAVLEFA-VIQTD
Mvan_5313|M.vanbaalenii_PYR-1       PASVALHVRNASPADGEAALAAAWEAAPEWEAHVTTGKAVLEFA-VIDTD
Mflv_1458|M.gilvum_PYR-GCK          PASVALHVRNASPADGDAALAAAWDAARDWDAHITTGKAVLEFA-VISTD
Mb2029|M.bovis_AF2122/97            RFAVAVHYRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVELRPDIAWD
Rv2006|M.tuberculosis_H37Rv         RFAVAVHYRNVADDSVDNLIAAVRRLGHAAGLRVTTGRKVVELRPDIAWD
MMAR_1156|M.marinum_M               RFGVATHYRNAARDRVGEIAAVVRAAGQRDGLRVTTGREVIELRPDIDWD
MUL_0921|M.ulcerans_Agy99           RFGVATHYRNAARNRVGKIAAVVRAAGQRDGLRVTTGREVIELHPDIDWD
MLBr_00414|M.leprae_Br4923          RFGVAVHYRNVARDRVNEVAVAVRTAGQRNALRVTTGREVIELRPDIDWD
MAV_4338|M.avium_104                RFGVAVHYRNAARDRVGEVAAAVRAAGRHDALRVTTGREVIELRPDLDWD
                                      .** * **.:          .   .     ::* *: *:*:   :  *

MAB_0578c|M.abscessus_ATCC_199      KGQALDILRHQEGAT---------AAVFFGDDVTDEKAFKRLHG---PDV
MSMEG_6043|M.smegmatis_MC2_155      KGEAVDILRQQENAT---------AVVFFGDDVTDEKAFRRLRG---DDV
Mvan_5313|M.vanbaalenii_PYR-1       KGAAVDILRGECDAT---------AVVFFGDDVTDEKAFARLRR---SDV
Mflv_1458|M.gilvum_PYR-GCK          KGEAVDILRERLQAT---------TVVFLGDDVTDEKAFVRLGE---SDV
Mb2029|M.bovis_AF2122/97            KGKALDWIGERLGPA--EVGPDLRLPIYIGDDLTDEDAFDAVRF---TGV
Rv2006|M.tuberculosis_H37Rv         KGKALDWIGERLGPA--EVGPDLRLPIYIGDDLTDEDAFDAVRF---TGV
MMAR_1156|M.marinum_M               KGKTLRWVIDHLPDQ----RAAPLVPIYLGDDITDEDAFDAVGP---NGV
MUL_0921|M.ulcerans_Agy99           KGKTLRWVIDHLPDQ----RAAPLVPIYLGDDITDEDAFDAVGP---NGV
MLBr_00414|M.leprae_Br4923          KGKTLHWVIDRLHHAGTQVGSASLMPICLGDDITDEDAFDAVRHTDVGGI
MAV_4338|M.avium_104                KGKTLHWVIEHLRRS----GSGALTPVYLGDDITDEDAFDAVRGGPVQGV
                                    ** ::  :  .               : :***:***.**  :      .:

MAB_0578c|M.abscessus_ATCC_199      GVKVGDGE-----TLAGYRIPDTESVGTALAFLLEERRTWLLGGHATPIE
MSMEG_6043|M.smegmatis_MC2_155      GVKVGPGE-----SLAAYRVDSPEDVAAALDHLLAVRR----GA------
Mvan_5313|M.vanbaalenii_PYR-1       GVKVGPGE-----SAAGYRIDSPDAVAAALEHLVASRK------------
Mflv_1458|M.gilvum_PYR-GCK          GVKVGPGD-----TAAAYRVESPADVATALRHLVDTRAAQ----------
Mb2029|M.bovis_AF2122/97            GIVVRHNEHGDRRSAATFRLECPYTVCQFLSQLACDLQEAVQHDDPWTLV
Rv2006|M.tuberculosis_H37Rv         GIVVRHNEHGDRRSAATFRLECPYTVCQFLSQLACDLQEAVQHDDPWTLV
MMAR_1156|M.marinum_M               AIMVRHNEDGDRATAALFALESPARVAEFTGRLASQLSTLG---------
MUL_0921|M.ulcerans_Agy99           AIMVRHNEDGDRATAALFALESPARVAEFTGRLASQLSTLG---------
MLBr_00414|M.leprae_Br4923          PIVVRHTEDGNRATAALFTLDSPMHVSEFTERLARQLSDTQR--------
MAV_4338|M.avium_104                PILVRHNDDGDRATAALFALDSPARAAEFTERLADQLERGEG--------
                                     : *   :     : * : :  .  .      *                 

MAB_0578c|M.abscessus_ATCC_199      RLTMLANSRTIALVTPTGDVTWMCHPEPDSAAVFAHLLGGPEAGHFTIGP
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       RLA-----------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          ------------------------SPQPAP--------------------
Mb2029|M.bovis_AF2122/97            FHGYDPGQERLREALCAVGNGYLGSRGCAPESAESEAHYPGTYVAGVYNQ
Rv2006|M.tuberculosis_H37Rv         FHGYDPGQERLREALCAVGNGYLGSRGCAPESAESEAHYPGTYVAGVYNQ
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      ARSALPLGQKYIDSTMTVETRWASLQVTDYLAHDEVPGRTDLIRVVTGEA
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            LTDHIEGCTVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELLSYRQTFDL
Rv2006|M.tuberculosis_H37Rv         LTDHIEGCTVDNESLVNLPNWLSLTFRIDGGAWFNVDTVELLSYRQTFDL
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      DAVVTFAPRPEFGQAPVQLVAEADGLRVLGTNDPIVLRAPGVTWTIGADD
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            RRATLTRSLRFRDAGGRVTTMTQERFASMNRPNLVALQTRIESENWSGTV
Rv2006|M.tuberculosis_H37Rv         RRATLTRSLRFRDAGGRVTTMTQERFASMNRPNLVALQTRIESENWSGTV
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      QTATATISPANGPIILELRCGTEDLGENPTSEPELRERAESYWRDWAQTL
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            DFRSLVDGGVHNTLVDRYRQLSSQHLTTAEIEVLADSVLLRTQTSQSGIA
Rv2006|M.tuberculosis_H37Rv         DFRSLVDGGVHNTLVDRYRQLSSQHLTTAEIEVLADSVLLRTQTSQSGIA
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      TLPERKPGLMKRSALTLRGLVHAESGAILAAATTSLPEDIGGIRNWDYRY
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            IAVAARSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQSVTLEKVAT
Rv2006|M.tuberculosis_H37Rv         IAVAARSTLWRDGQRVDAQYRVARDTNRGGHDIQVTLSAGQSVTLEKVAT
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      CWLRDASMTASALVALGSLSEAEGLLGWLHRVLEHLPGPDRLHPLYTLAG
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            IFTSRDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLWERCAIDLTG
Rv2006|M.tuberculosis_H37Rv         IFTSRDAATLTAAISAQRCLGEAGRYAELCQQHVRAWARLWERCAIDLTG
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      TALPPEAVIDSLPGYAGSRPVRVGNAANSQVQLDVFGPVVELIHDLSHAR
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            NTEELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYRGHVFWDALF
Rv2006|M.tuberculosis_H37Rv         NTEELRLVRLHLLHLLQTISPHTAELDAGVPARGLNGEAYRGHVFWDALF
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      KHLGHSDPLTDADWNLVSDMVLAVERRWYEPDHGIWEIRGNPRHHVYSKV
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            VAPVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMYPWQSGSDGS
Rv2006|M.tuberculosis_H37Rv         VAPVLSLRMPKVARSLLDYRYRRLPAARRAAHRAGHLGAMYPWQSGSDGS
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      MCWVTVDRAVKLAEEFERAAPSSWAALRDEIAAEVIEKGWNESVNSYTAA
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            EVSQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVTGDRQYLVDC
Rv2006|M.tuberculosis_H37Rv         EVSQQLHLNPRSGRWTPDPSDRAHHVGLAVAYNAWHYYQVTGDRQYLVDC
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      YDGTDLDAATLYIGLSGLIDPTDPRFTATVIATEAELR-SGATVYRYHRD
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            GAELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYPGNEYDGIDN
Rv2006|M.tuberculosis_H37Rv         GAELLVEIARFWVGLAKLDDSRGRYLIRGVIGPDEFHSGYPGNEYDGIDN
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      DCLPGGEGGFHLCAAWLVEAYLLIGARSQAELLFDQLVKATGPTGLLSEE
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            NAYTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQERDQWDDVSRR
Rv2006|M.tuberculosis_H37Rv         NAYTNVMAVWVILRAMEALDLLPLTDRRHLIEKLGLTTQERDQWDDVSRR
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      YDPVAERSLGNHPQAYSHIGLLRCAALLS---------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            MFVPFHDGVISQFEGYSELAELDWDHYRHRYGNIQRLDRILEAEGDSVNN
Rv2006|M.tuberculosis_H37Rv         MFVPFHDGVISQFEGYSELAELDWDHYRHRYGNIQRLDRILEAEGDSVNN
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            YQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTVDYYLARTSD
Rv2006|M.tuberculosis_H37Rv         YQASKQADALMLLYLLSSDELIGLLARLGYRFAPTQIPGTVDYYLARTSD
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            GSTLSAVVHAWVLARANRSNAMEYFRQVLRSDIADVQGGTTQEGIHLAAM
Rv2006|M.tuberculosis_H37Rv         GSTLSAVVHAWVLARANRSNAMEYFRQVLRSDIADVQGGTTQEGIHLAAM
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2029|M.bovis_AF2122/97            AGSIDLPQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYRRHQLSLRIS
Rv2006|M.tuberculosis_H37Rv         AGSIDLLQRCYSGLELRDDRLVLSPQWPEALGPLEFPFVYRRHQLSLRIS
MMAR_1156|M.marinum_M               --------------------------------------------------
MUL_0921|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00414|M.leprae_Br4923          --------------------------------------------------
MAV_4338|M.avium_104                --------------------------------------------------
                                                                                      

MAB_0578c|M.abscessus_ATCC_199      ---------------------------------------
MSMEG_6043|M.smegmatis_MC2_155      ---------------------------------------
Mvan_5313|M.vanbaalenii_PYR-1       ---------------------------------------
Mflv_1458|M.gilvum_PYR-GCK          ---------------------------------------
Mb2029|M.bovis_AF2122/97            GRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR
Rv2006|M.tuberculosis_H37Rv         GRSATLTAESGDAEPIEVECRGHVQRLRCGHTIEVGCSR
MMAR_1156|M.marinum_M               ---------------------------------------
MUL_0921|M.ulcerans_Agy99           ---------------------------------------
MLBr_00414|M.leprae_Br4923          ---------------------------------------
MAV_4338|M.avium_104                ---------------------------------------