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RAYRGHLIHIGGSPRLDSAREHLVSVPDGVLVVNDAGSIAYSGSYQEMPAYPDTEMHDCRPGFLLPGFID THIHYPQTHCIDSYGGGQLLDWLQHCIFPAEAKLADRDYARDVARDFCRRRVAVGTTTALVFGSAFPDAQ DTLFEESARIGLRTISGRGIQTVGPEAAGPLLTDDDTAIALTHSEIDRWHNAEGGLVKVAVVPRFALSVT GRTLHALGELYDAVRGRGVYFHTHLSENVTEIDAVRTTYGVENYLDTYDGRFDGGGLSLLGPRSVFAHAV HCTDGELNRLSETGSSIAHCPTSQLFLGSGTMPWRRTVASGVNVALGTDVSAGDEWLIPRVLNDCFKVHI SEPGGQGLSISPAALLFTATLAGARALQMEDRIGNLDVGKEADFVVIDPRCQPLLSELLTPIAPDDADRL LFTLLLSMREDAVGGVYVRGRLLSPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5279 | - | - | 100% (447) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_0863 | - | 2e-20 | 26.67% (375) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_3147 | - | 4e-18 | 24.26% (404) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2928 | - | 1e-150 | 60.18% (452) | amidohydrolase |
| M. marinum M | MMAR_2844 | - | 3e-27 | 28.68% (380) | metal-dependent hydrolase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1298 | - | 1e-178 | 70.00% (450) | guanine deaminase |
| M. thermoresistible (build 8) | TH_3859 | - | 4e-18 | 26.72% (363) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2914 | - | 8e-27 | 28.42% (380) | hydroxydechloroatrazine ethylaminohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2844|M.marinum_M MSTILLTLMLECRVPKLVIDRVS-IATVDPKAAEFSEGHIIVEDDLIVAV
MUL_2914|M.ulcerans_Agy99 --------MLECRVPKLVIDRIS-IATVDPKAAEFSEGHIIVEDDLIVAV
Mvan_5279|M.vanbaalenii_PYR-1 --------MRAYRGHLIHIGGSPRLDSAREHLVSVPDGVLVVNDAGSIAY
MSMEG_1298|M.smegmatis_MC2_155 --------MTTYRGHLIHIGGAPRLADAAQCLVSEPDGAIVVDDTGRITY
MAB_2928|M.abscessus_ATCC_1997 ---MEPIAATVHRGHIFHITGAPPLADAATHLQSIRDGALAVGTDGVIAY
TH_3859|M.thermoresistible__bu ------------------------VLAGDPLTAHVRAADLLIEDGRVTAI
: . : : :
MMAR_2844|M.marinum_M GD--GPAPEVPGATVIDGRGCLATPGLVNTHEHLYQWITRGYTQKGTLFQ
MUL_2914|M.ulcerans_Agy99 GD--GPAPEVPGATVIDGRGCLATPGLVNTHEHLYQWITRGHTQKGTLFQ
Mvan_5279|M.vanbaalenii_PYR-1 SGSYQEMPAYPDTEMHDCRPGFLLPGFIDTHIHYPQTHCIDSYGGGQLLD
MSMEG_1298|M.smegmatis_MC2_155 SGPFDRRPS--GDAVVDVRPAFLLPGFVDAHIHFPQTYCTDSYGGGQLLD
MAB_2928|M.abscessus_ATCC_1997 CGPYSTLPQEFTSWTEHHHGGFLLPGFVDTHMHFPQVYCTDSYGGGQLLE
TH_3859|M.thermoresistible__bu ES----DLAGVDAEIIDATGRWVLPGFVDTHRHLWQTTMRGLTANWNLKD
. . **::::* * * . * :
MMAR_2844|M.marinum_M WLT-EMYPVWGRLDAELEFAAASAGLAG-LALTGCTTTMDHHYVFPHAGG
MUL_2914|M.ulcerans_Agy99 WLT-EMYPVWGRLDAELEFAAASAGLAG-LALTGCTTTMDHHYVFPHAGG
Mvan_5279|M.vanbaalenii_PYR-1 WLQHCIFPAEAKLADRDYARDVARDFCRRRVAVGTTTALVFGSAFPDAQD
MSMEG_1298|M.smegmatis_MC2_155 WLSRCIFPAEVKLADPAYAQRVAQDFCRRRISVGTTTALVFGSAFPHAQD
MAB_2928|M.abscessus_ATCC_1997 WLERCIFPAEARLADTALAQRAAIAFCRRRIAAGTTAAMVMGSAFPQAQE
TH_3859|M.thermoresistible__bu YFW-CIRSHFAGLHDPDDVYGGQYAGGLDALVNGVTTTIDHSHITNSPD-
:: : . * * *::: .
MMAR_2844|M.marinum_M DMLGAEIAAAKRIGVRFHPTRGSMDLGVASGGLPPEHTVEDIDTILTTCQ
MUL_2914|M.ulcerans_Agy99 DMLGAEIVAAKRIGVRFHPTRGSMDLGVASGGLPPEHTVEDIDTILTTCQ
Mvan_5279|M.vanbaalenii_PYR-1 TLF----EESARIGLRTISGRGIQTVGPEA----AGPLLTDDDTAIALTH
MSMEG_1298|M.smegmatis_MC2_155 ALF----RESIRTGLRTISGRGIQTVGPPS----AEPLLTDEATAISLVT
MAB_2928|M.abscessus_ATCC_1997 ALF----TATRAAGLRMVSGRGVQTVGPRS----AEPLLTTTERATELCA
TH_3859|M.thermoresistible__bu ------HSDAAVRGLLDSGVRALWCYGFYPSP-QADPVFTTPQHRLDDAR
: *: *. * . . .
MMAR_2844|M.marinum_M DAVREHHDPTKG----SMVQISLAPCSPFSVTGELMKQSALL---ARDLG
MUL_2914|M.ulcerans_Agy99 DAVREHHDPTKG----SMVQISLAPCSPFSVTGELMKQSALL---ARDLG
Mvan_5279|M.vanbaalenii_PYR-1 SEIDRWHNAEGG-----LVKVAVVPRFALSVTGRTLHALGELYDAVRGRG
MSMEG_1298|M.smegmatis_MC2_155 EEIVRWHAADTGDPATALVHAAVVPRFALSVTTQTLHALGELYDSVRDRG
MAB_2928|M.abscessus_ATCC_1997 NEIQSWHGDELT-------DVALVPRFSLSVTAETLAALGELYEDVRADG
TH_3859|M.thermoresistible__bu RVRSTFFPTDDG----------------LVRMGVALTELGMQPFTETQRE
. : : .
MMAR_2844|M.marinum_M VRLHTHLSETVE----EDEFCLAQFGSR-PVDYVES----------LGWL
MUL_2914|M.ulcerans_Agy99 VRLHTHLSETVE----EDEFCLAQFGSR-PVDYVES----------LGWL
Mvan_5279|M.vanbaalenii_PYR-1 VYFHTHLSENVT----EIDAVRTTYGVENYLDTYDGRFD----GGGLSLL
MSMEG_1298|M.smegmatis_MC2_155 VYFHTHLNENVD----EVAAVRETYGVQSYLDTYDS--------IGKTLL
MAB_2928|M.abscessus_ATCC_1997 VYFHSHLNENARPDTGEVDATLTAYGVGSYLDTYDGHFLPGSRKGGATLL
TH_3859|M.thermoresistible__bu LQTAEDLAVPVT----MHTNCVWTRPEFHDVELYHR----------AGLL
: .* . :: . *
MMAR_2844|M.marinum_M GSDVWMAHCVHLSKGDIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAA
MUL_2914|M.ulcerans_Agy99 GSDVWMAHCVHLSKGYIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAA
Mvan_5279|M.vanbaalenii_PYR-1 GPRSVFAHAVHCTDGELNRLSETGSSIAHCPTSQLFLGSGTMPWRRTVAS
MSMEG_1298|M.smegmatis_MC2_155 GPRSVLAHAVHCTRDELARMADTGTSIAHCPSSQLFLGSGVMPWRATVGS
MAB_2928|M.abscessus_ATCC_1997 GRRSILAHAVHCQDAELARMAETGSSIAHCPTSQLFLGSGTMPWRRTVAS
TH_3859|M.thermoresistible__bu RAGQIHSHANRCSDHELALLRDAGCAVSSTPDTELQMGCGRPVFRRALAT
:*. : : : :* .:: * :: :*.* :.:
MMAR_2844|M.marinum_M DVAVGLGVDGAGAE--------HRGLANEMRQAALAARFRLGP----QAL
MUL_2914|M.ulcerans_Agy99 DVAVGLGVDGAGAE--------HRGLANEMRQAALAARFRLGP----QAL
Mvan_5279|M.vanbaalenii_PYR-1 GVNVALGTDVSAGD--------EWLIPRVLNDCFKVHISEPGG----QGL
MSMEG_1298|M.smegmatis_MC2_155 GVNVALGTDVSAGD--------EWLIPRVLNDCFKVHMSEPGD----QAV
MAB_2928|M.abscessus_ATCC_1997 GVNIALGTDVGGGD--------EWLLTRVLNDCFKVHMSEPGP----AAV
TH_3859|M.thermoresistible__bu GVTAGIGIDIVSNNSGDMFTAMRVLMQHERGDALQPTLEESGLTAVAEPL
.* .:* * . : . : . :. . * :
MMAR_2844|M.marinum_M DAR--EALWMATVGGARCLGRDQDLGSLEVGKLADIALWQLDGLGH-SDV
MUL_2914|M.ulcerans_Agy99 DAR--EALWMATVGGARCLGRDQDLGSLEVGKLADIALWQLDGLGH-SDV
Mvan_5279|M.vanbaalenii_PYR-1 SISPAALLFTATLAGARALQMEDRIGNLDVGKEADFVVIDP-------RC
MSMEG_1298|M.smegmatis_MC2_155 ALHPAELLFTATLAGARALALEDRIGNLDAGKEADFVVVDA-------RR
MAB_2928|M.abscessus_ATCC_1997 SLHPAELLFTATLAGARALDREDTFGNLDAGKEADFLVVVPD------RW
TH_3859|M.thermoresistible__bu PVTTRQILHAATLAGARALGLESVCGSIDVGKSADLLLLRHDRLHMRPVI
* **:.***.* :. *.::.** **: :
MMAR_2844|M.marinum_M EDPVWALIYGPPAPLRLLLVGGNTVVEDGELRTADTETLATDAKNAAVTL
MUL_2914|M.ulcerans_Agy99 EDPVWALIYGPPAPLRLLLVGGNTVVEDGELRTADTETLATDAKNAAVTL
Mvan_5279|M.vanbaalenii_PYR-1 QPLLSELLTPIAPDDA----DRLLFTLLLSMREDAVGGVYVRGRLLSPR-
MSMEG_1298|M.smegmatis_MC2_155 QELLVESLSQIDEYDR----AAQLFTLLMGMREEAVSQVYVKGRKLN---
MAB_2928|M.abscessus_ATCC_1997 EPLANNLFHGIRSDDERLADEQTLFRLLMGLREPAISAVLVRGRDITGYL
TH_3859|M.thermoresistible__bu DDIDSIVLQATTRDIDRVLVAGRTVVQDGRLPAAVERRGVAAIEAAHSRL
: : . : . .
MMAR_2844|M.marinum_M RERG-----------------------------------
MUL_2914|M.ulcerans_Agy99 RERG-----------------------------------
Mvan_5279|M.vanbaalenii_PYR-1 ---------------------------------------
MSMEG_1298|M.smegmatis_MC2_155 ---------------------------------------
MAB_2928|M.abscessus_ATCC_1997 HSDR-----------------------------------
TH_3859|M.thermoresistible__bu AERVAAVGGWKLAVPQGLMDQLGVTFHDNVANTPAQANS