For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTDDPVIIHTDGGCRPNPGPGGWGAVLRQRDHVREMFGGEAGATSNNRMELMAPIMALEALTRPVVVHLH TDSTYVRNGITKWVFGWERNGWMTAAKQPVKNVDLWQRLQIASAQHRVEWFWVKGHSGIADNELADALAT RGLQEAIAAAAIPT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4905 | rnhA | - | 100% (154) | ribonuclease H |
| M. vanbaalenii PYR-1 | Mvan_3618 | - | 5e-06 | 30.82% (146) | bifunctional RNase H/acid phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2253c | - | 6e-06 | 29.61% (152) | bifunctional RNase H/acid phosphatase |
| M. gilvum PYR-GCK | Mflv_1836 | rnhA | 8e-75 | 84.56% (149) | ribonuclease H |
| M. tuberculosis H37Rv | Rv2228c | - | 6e-06 | 29.61% (152) | bifunctional RNase H/acid phosphatase |
| M. leprae Br4923 | MLBr_01637 | - | 7e-05 | 42.86% (56) | bifunctional RNase H/acid phosphatase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3304 | - | 6e-05 | 27.78% (162) | hypothetical protein MMAR_3304 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5562 | rnhA | 4e-77 | 87.76% (147) | RNase H |
| M. thermoresistible (build 8) | TH_0602 | rnhA | 1e-76 | 86.00% (150) | RNase H |
| M. ulcerans Agy99 | MUL_1324 | - | 4e-05 | 27.78% (162) | bifunctional RNase H/acid phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3304|M.marinum_M ------MKVIIEADGGSRGNPGPAGYGAVVWTADRSTVLAESKQAIGRAT
MUL_1324|M.ulcerans_Agy99 ------MKVIIEADGGSRGNPGPAGYGAVVWTADRSTVLAESKQAIGRAT
Mb2253c|M.bovis_AF2122/97 ------MKVVIEADGGSRGNPGPAGYGAVVWTADHSTVLAESKQAIGRAT
Rv2228c|M.tuberculosis_H37Rv ------MKVVIEADGGSRGNPGPAGYGAVVWTADHSTVLAESKQAIGRAT
MLBr_01637|M.leprae_Br4923 ------MKVIIEADGGSRGNPGPAGYGAVVWIADRSAVLTETKQAIGRAT
Mvan_4905|M.vanbaalenii_PYR-1 ---MTDDPVIIHTDGGCRPNPGPGGWGAVLRQRDHVREMFGGE--AGATS
MSMEG_5562|M.smegmatis_MC2_155 ---MSQDPVIIHTDGGCRPNPGPGGWGAVLRHREHVREMFGGE--AAVTS
TH_0602|M.thermoresistible__bu MSAFDEAPVIIHTDGGCRPNPGPGGWGAVLRQGRHVREIFGGD--AGVTS
Mflv_1836|M.gilvum_PYR-GCK ---MS-DVVVIHTDGGCRPNPGPGGWGAVLRQRHHVREMCGGE--PAQTS
*:*.:***.* ****.*:***: : : . . ::
MMAR_3304|M.marinum_M NNVAEYRGLIAGLDDAVKLGATEVSVLMDSKLVVEQMCGRWKVKHPDLVE
MUL_1324|M.ulcerans_Agy99 NNVAEYRGLIAGLDDAVKLGATEVSVLMDSKLVVEQMCGRWKVKHPDLVE
Mb2253c|M.bovis_AF2122/97 NNVAEYRGLIAGLDDAVKLGATEAAVLMDSKLVVEQMSGRWKVKHPDLLK
Rv2228c|M.tuberculosis_H37Rv NNVAEYRGLIAGLDDAVKLGATEAAVLMDSKLVVEQMSGRWKVKHPDLLK
MLBr_01637|M.leprae_Br4923 NNVAEYRALIAGLDDAVKMGATEAEVLMDSKLVVEQMSGRWKVKHPDLIE
Mvan_4905|M.vanbaalenii_PYR-1 NNRMELMAPIMALEALTR---------------------------PVVVH
MSMEG_5562|M.smegmatis_MC2_155 NNRMELTAPIMALEALTR---------------------------PVTVH
TH_0602|M.thermoresistible__bu NNRMELTAPIMALEALTR---------------------------PVVVH
Mflv_1836|M.gilvum_PYR-GCK NNRMELTAPIMALEALTR---------------------------PVSVH
** * . * .*: .: * :.
MMAR_3304|M.marinum_M LHGQARELAGQFRRISYAWIPRARNAHADRLANEAMDAAVRTNRRGEPGT
MUL_1324|M.ulcerans_Agy99 LHGQARELAGQFRRISYAWIPRARNAHADQLANEAMDAAVRTNRRGEPGT
Mb2253c|M.bovis_AF2122/97 LYVQAQALASQFRRINYEWVPRARNTYADRLANDAMDAAAQS--------
Rv2228c|M.tuberculosis_H37Rv LYVQAQALASQFRRINYEWVPRARNTYADRLANDAMDAAAQS--------
MLBr_01637|M.leprae_Br4923 LYVHAQTLASRLASVSYTWIPRTRNSRADRLANEAMDAASCAEGR---VD
Mvan_4905|M.vanbaalenii_PYR-1 LHTDSTYVRNGITKWVFGWE---RN-------------------------
MSMEG_5562|M.smegmatis_MC2_155 LYTDSTYVRNGITKWVLGWE---RN-------------------------
TH_0602|M.thermoresistible__bu LHTDSTYVRNGITTWVHGWE---RN-------------------------
Mflv_1836|M.gilvum_PYR-GCK LYTDSTYVRNGITKWVLGWE---RN-------------------------
*: .: : . : * **
MMAR_3304|M.marinum_M VAVAAVADPANTAPVQTPAAPGWTGRRDTATRLLLLRHGQTELSVQRRYS
MUL_1324|M.ulcerans_Agy99 VAVAAVADPANTAPVQTPAAPGWTGRRDTATRLLLLRHGQTELSVQRRYS
Mb2253c|M.bovis_AF2122/97 --AAADADPAKIVATESPTSPGWTGARGTPTRLLLLRHGQTELSEQRRYS
Rv2228c|M.tuberculosis_H37Rv --AAADADPAKIVATESPTSPGWTGARGTPTRLLLLRHGQTELSEQRRYS
MLBr_01637|M.leprae_Br4923 QAATQLAQSTKAVAKESQTAPGWTGARGTPTRLLLLRHGQTELSVQRRYS
Mvan_4905|M.vanbaalenii_PYR-1 ---------------------GWMTAAKQPVKNVDLWQRLQIASAQ----
MSMEG_5562|M.smegmatis_MC2_155 ---------------------GWMTAAKQPVKNVDLWQRLQAACAR----
TH_0602|M.thermoresistible__bu ---------------------GWMTAARQPVKNVDLWQRLQAACAR----
Mflv_1836|M.gilvum_PYR-GCK ---------------------GWMTAAKQPVKNADLWRRLQSACAR----
** ..: * : . :
MMAR_3304|M.marinum_M GRGNPALNEVGWRQAGLAARYIAHRGGIAAVVSSPLQRAYDTATTAARAL
MUL_1324|M.ulcerans_Agy99 GRGNPALNEVGWRQAGLAARYIAHRGGIAAVVSSPLQRAYDTATTAARAL
Mb2253c|M.bovis_AF2122/97 GRGNPGLNEVGWRQVGAAAGYLARRGGIAAVVSSPLQRAYDTAVTAARAL
Rv2228c|M.tuberculosis_H37Rv GRGNPGLNEVGWRQVGAAAGYLARRGGIAAVVSSPLQRAYDTAVTAARAL
MLBr_01637|M.leprae_Br4923 GRGNPALNNVGWRQARAAARYFAQRGGIAGVVSSPLQRAYDTAATVADLL
Mvan_4905|M.vanbaalenii_PYR-1 -------HRVEWFWVKGHSG-IADNELADALATRGLQEAIAAAAIPT---
MSMEG_5562|M.smegmatis_MC2_155 -------HQVEWFWVKGHSG-IGDNELADELATRGLQEAVGLTTSSAGTS
TH_0602|M.thermoresistible__bu -------HRVEWFWVKGHSG-VADNELADQLAARGLRQALEAAALLT---
Mflv_1836|M.gilvum_PYR-GCK -------HEVEWFWVKGHSG-VADNELADVLATRGLQEALAASVV-----
:.* * . : .. . :.: *:.* :.
MMAR_3304|M.marinum_M GLDVTVDEDLVETDFGDWEGMTFAEAANRDPDLHHRWLNDTSITPPGGES
MUL_1324|M.ulcerans_Agy99 GLDVTVDEDLVETDFGDWEGMTFAEAANRDPDLHHRWLNDTSITPPGGES
Mb2253c|M.bovis_AF2122/97 ALDVVVDDDLVETDFGAWEGLTFAEAAERDPELHRRWLQDTSITPPGGES
Rv2228c|M.tuberculosis_H37Rv ALDVVVDDDLVETDFGAWEGLTFAEAAERDPELHRRWLQDTSITPPGGES
MLBr_01637|M.leprae_Br4923 GANLTVDDDLIEIDFGAWEGLTFAEAAARDPQLHHCWLHDTATLPPGGES
Mvan_4905|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5562|M.smegmatis_MC2_155 LR------------------------------------------------
TH_0602|M.thermoresistible__bu --------------------------------------------------
Mflv_1836|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3304|M.marinum_M FDEVLRRVRRGRDRMISRYEGTTVLVVSHVTPIKMLLRLALDVGSEVLYR
MUL_1324|M.ulcerans_Agy99 FDEVLRRVRRGRDRMISRYEGTTVLVVSHVTPIKMLLRLALDVGSEVLYR
Mb2253c|M.bovis_AF2122/97 FDDVLRRVRRGRDRIIVGYEGATVLVVSHVTPIKMLLRLALDAGSGVLYR
Rv2228c|M.tuberculosis_H37Rv FDDVLRRVRRGRDRIIVGYEGATVLVVSHVTPIKMLLRLALDAGSGVLYR
MLBr_01637|M.leprae_Br4923 FDDVLGRVCSARARIIAEYQGETVLVVSHVTPIKMLLRLALDAGAGILYR
Mvan_4905|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5562|M.smegmatis_MC2_155 --------------------------------------------------
TH_0602|M.thermoresistible__bu --------------------------------------------------
Mflv_1836|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3304|M.marinum_M LHLDLASLSIAEFYADGASSVRLVNQTGYL
MUL_1324|M.ulcerans_Agy99 LHLDLASLSIAEFYADGASSVRLVNQTGYL
Mb2253c|M.bovis_AF2122/97 LHLDLASLSIAEFYADGASSVRLVNQTGYL
Rv2228c|M.tuberculosis_H37Rv LHLDLASLSIAEFYADGASSVRLVNQTGYL
MLBr_01637|M.leprae_Br4923 LHLDLGSLSIAEFYPDGASSVRLVNQTGYL
Mvan_4905|M.vanbaalenii_PYR-1 ------------------------------
MSMEG_5562|M.smegmatis_MC2_155 ------------------------------
TH_0602|M.thermoresistible__bu ------------------------------
Mflv_1836|M.gilvum_PYR-GCK ------------------------------