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DEVFRALADPSRRRLLDSLNARNGQSLRELCAGLDMARQSVSKHLKVLEDANLVSTVWRGREKLHYLNAE PINAIADRWINHYDRLRAQTLADLKTALEQDTMEHDNDFVYTTYIRTTPERLWQAVTDPAFSERYMGHGL VTDWKVGSTFDWRDGDLNISNPEQVVLEADPYRRLAFTFHTFTRQLTTVGLSEDVIDRAAAEPRSKVSFD IEQVDGGRVKLTVIHTGFPSGSIVRELVSGGWPSKLSDLKSNLELASVTADA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4686 | - | - | 100% (263) | regulatory protein, ArsR |
| M. vanbaalenii PYR-1 | Mvan_3372 | - | 1e-17 | 48.24% (85) | regulatory protein, ArsR |
| M. vanbaalenii PYR-1 | Mvan_2636 | - | 8e-10 | 41.11% (90) | regulatory protein, ArsR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0591 | - | 4e-08 | 24.27% (239) | ArsR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2031 | - | 1e-129 | 84.33% (268) | activator of Hsp90 ATPase 1 family protein |
| M. tuberculosis H37Rv | Rv0576 | - | 4e-08 | 24.27% (239) | ArsR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0986 | - | 3e-51 | 45.88% (255) | ArsR family transcriptional regulator |
| M. marinum M | MMAR_5343 | - | 1e-18 | 52.38% (84) | transcriptional regulator |
| M. avium 104 | MAV_2783 | - | 5e-13 | 39.81% (103) | ArsR family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3497 | - | 5e-56 | 46.27% (255) | transcriptional regulator, ArsR family protein |
| M. thermoresistible (build 8) | TH_2906 | - | 6e-10 | 34.26% (108) | PUTATIVE transcriptional regulator, ArsR family |
| M. ulcerans Agy99 | MUL_0086 | - | 6e-18 | 51.19% (84) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4686|M.vanbaalenii_PYR-1 -----------MDEVFRALADPSRRRLLDSLNARNGQSLRELCA------
Mflv_2031|M.gilvum_PYR-GCK -----------MDEVFRALADPSRRRLLDNLNARNGQSLRELCA------
MSMEG_3497|M.smegmatis_MC2_155 -----------MEAVLKALSDANRRTLLARLGDRDGQTLKELCA------
MMAR_5343|M.marinum_M MHIVREVGD-----VFKALADPTRRVILDELTDRNGQTLFEICARLTTKH
MUL_0086|M.ulcerans_Agy99 ---MREVGD-----VFKALADPTRRVILGELTDRNGQTLFEICARLTTKH
MAB_0986|M.abscessus_ATCC_1997 --MQSAPGHSHWDVVFKALADPTRRELLDRLHERNGQTLSQLCE------
MAV_2783|M.avium_104 -----MVVVTGVDRVFLALANPVRRELLQLL-ARHPLSAGELSER-----
Mb0591|M.bovis_AF2122/97 --------------MLEVAAEPTRRRLLQLLAPGER-TVTQLAS------
Rv0576|M.tuberculosis_H37Rv --------------MLEVAAEPTRRRLLQLLAPGER-TVTQLAS------
TH_2906|M.thermoresistible__bu ----------VQATIFGALGEPSRLRIVELLRAGPH-SVGEIAE------
:: . .:. * :: * : ::.
Mvan_4686|M.vanbaalenii_PYR-1 GLDMARQSVSKHLKVLEDANLVSTVWRGREKLHYLNAEPINAIADRWINH
Mflv_2031|M.gilvum_PYR-GCK GLDMARQSVSKHLKVLEDANLVSIVWQGREKLHYLNAEPINAIADRWINH
MSMEG_3497|M.smegmatis_MC2_155 DLAMARQSVAKHLEVLEAAGLVTVQWEGRQKLHHLDTGPITELAGELTAR
MMAR_5343|M.marinum_M GICSTRQAISQHLDVLEAAELIETQRGGRQKFHYLNTAPLGQIAKRWR--
MUL_0086|M.ulcerans_Agy99 GICSTRQAISQHLDVLEAAGLIETQRGGRQKFHYLNTAPLGQIAKRWR--
MAB_0986|M.abscessus_ATCC_1997 GVAMARQSATQHLGVLESANLISTVRHGREKLHYLNPVPLHEIQERWIDK
MAV_2783|M.avium_104 -FELSRPAVAEHLKVLREAALVADERRGRQRIYHLTAEPLAELGEWLHP-
Mb0591|M.bovis_AF2122/97 QFTVTRSAISQHLGMLAEAGLVTARKQGRERYYRLDERGVLRLRALMESF
Rv0576|M.tuberculosis_H37Rv QFTVTRSAISQHLGMLAEAGLVTARKQGRERYYRLDERGVLRLRALMESF
TH_2906|M.thermoresistible__bu ALGIRQPQVSKHLRVLADSGIVTGEARARQRIYRLEAAPFEQIGRWAES-
. : ::** :* : :: .*:: : * . :
Mvan_4686|M.vanbaalenii_PYR-1 YDRLRAQTLADLKTALEQDTMEHDN-----DFVYTTYIRTTPERLWQAVT
Mflv_2031|M.gilvum_PYR-GCK YDRMRAQTLADLKTALERNPMADNTHSAAADFVYTTYIRTTPERLWQAVT
MSMEG_3497|M.smegmatis_MC2_155 WGAPRRHG-----ARLEAGAGNDGD-----VFVYVIYIRTTPERLWHAIT
MMAR_5343|M.marinum_M --------------------------------------------------
MUL_0086|M.ulcerans_Agy99 --------------------------------------------------
MAB_0986|M.abscessus_ATCC_1997 FERPRLRALSAIKQRAEERDMSQPT------FVYTTYINSTPEKVWQAIT
MAV_2783|M.avium_104 --------------------------------------------------
Mb0591|M.bovis_AF2122/97 WSDELDRLVADAAHYPPSQGDCAMP------FEKAVVVPLDPTSTFALIT
Rv0576|M.tuberculosis_H37Rv WSDELDRLVADAAHYPPSQGDCAMP------FEKAVVVPLDPTSTFALIT
TH_2906|M.thermoresistible__bu -------------------------------FEQVWEARLDSLGEFLESI
Mvan_4686|M.vanbaalenii_PYR-1 DPAFSERYMGHGLVTDWKVGSTFDWR-DGDLNISNPEQVVLEADPYRRLA
Mflv_2031|M.gilvum_PYR-GCK DPAFSERYMGHGLVSDWQVGSTFAWR-DGDLSITSPEQVILECEPYRRLA
MSMEG_3497|M.smegmatis_MC2_155 NPGTSLGYLGHAIESDWLKGSTYVWI-ERGIRFERPQQVVLESDPYQRLA
MMAR_5343|M.marinum_M --------------------------------------------------
MUL_0086|M.ulcerans_Agy99 --------------------------------------------------
MAB_0986|M.abscessus_ATCC_1997 DPELSGQYWGHANVSDWQEGSRWEHRRTDGSGIADVVGTVVESDPPRKLV
MAV_2783|M.avium_104 --------------------------------------------------
Mb0591|M.bovis_AF2122/97 QPDRLRRWMAVAARIELRTGGAYRWT---VTPGHSAAGTVIDVDPGKRVV
Rv0576|M.tuberculosis_H37Rv QPDRLRRWMAVAARIELRTGGAYRWT---VTPGHSAAGTVIDVDPGKRVV
TH_2906|M.thermoresistible__bu TP----------------------------------EGTADDVDPDR---
Mvan_4686|M.vanbaalenii_PYR-1 FTFHTFTRQL-----TTVGLSEDVIDRAAAEPRSKVSFDIEQVDGGRVKL
Mflv_2031|M.gilvum_PYR-GCK FTFHTFTKDL-----TTVGLSEDVIERAAAEPRSQVVFDIESVEDGRVKL
MSMEG_3497|M.smegmatis_MC2_155 FTYP-------------MPRTPDLDDPGAEHDTTRVSFDIEPGE-HQVKL
MMAR_5343|M.marinum_M ------------------------IDTADS-GRGTT--------------
MUL_0086|M.ulcerans_Agy99 ------------------------IDTADS-GRGTT--------------
MAB_0986|M.abscessus_ATCC_1997 TTWA------------------DPADGADA-AVSTVTFLIQPYQ-NIVRL
MAV_2783|M.avium_104 ------------------------FEKFWRTRLRRLAEVAEELE------
Mb0591|M.bovis_AF2122/97 FTWGWEDHGDPPPGGSTVTITLTPVDGGTEVRLVHDGLTAQQAARHAKGW
Rv0576|M.tuberculosis_H37Rv FTWGWEDHGDPPPGGSTVTITLTPVDGGTEVRLVHDGLTAQQAARHAKGW
TH_2906|M.thermoresistible__bu --------------------------------------------------
Mvan_4686|M.vanbaalenii_PYR-1 TVIHTGFPSGSIVRELVSGGWPSKLSDLKSNLELASVTADA---------
Mflv_2031|M.gilvum_PYR-GCK TVTHTGFPSESIVRELVSGGWPSKLSDLKTHLELDRVAVGA---------
MSMEG_3497|M.smegmatis_MC2_155 TLVHDGLRPDSITHTLVSGEWPLKLSDLKSGLEQLTAP------------
MMAR_5343|M.marinum_M --------------------------------------------------
MUL_0086|M.ulcerans_Agy99 --------------------------------------------------
MAB_0986|M.abscessus_ATCC_1997 TVSHADL-ADPAEYAQASGGWAAVLSNLKSFLETGAPLPTEPWTQPG---
MAV_2783|M.avium_104 --------------------------------------------------
Mb0591|M.bovis_AF2122/97 NHFLDRLVVAGQHGDAGPDEWAAAPDPLDELSCAEATLAVLQHVLRGIGA
Rv0576|M.tuberculosis_H37Rv NHFLDRLVVAGQRGDAGPDEWAAAPDPLDELSCAEATLAVLQHVLRGIGA
TH_2906|M.thermoresistible__bu --------------------------------------------------
Mvan_4686|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2031|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3497|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5343|M.marinum_M --------------------------------------------------
MUL_0086|M.ulcerans_Agy99 --------------------------------------------------
MAB_0986|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2783|M.avium_104 --------------------------------------------------
Mb0591|M.bovis_AF2122/97 SDLTRQTPCTEYDVSQLADHLLRSLAIIGAAAGAQLAPRDVDAPLETQVA
Rv0576|M.tuberculosis_H37Rv SDLTRQTPCTEYDVSQLADHLLRSLAIIGAAAGAQLAPRDVDAPLETQVA
TH_2906|M.thermoresistible__bu --------------------------------------------------
Mvan_4686|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2031|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3497|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5343|M.marinum_M --------------------------------------------------
MUL_0086|M.ulcerans_Agy99 --------------------------------------------------
MAB_0986|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2783|M.avium_104 --------------------------------------------------
Mb0591|M.bovis_AF2122/97 DAAQAVMEAWRRRGLAGTVELNSNQVPATVPVGILCLEFLVHAWDFAIAT
Rv0576|M.tuberculosis_H37Rv DAAQAVMEAWRRRGLAGTVELNSNQVPATVPVGILCLEFLVHAWDFAIAT
TH_2906|M.thermoresistible__bu --------------------------------------------------
Mvan_4686|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2031|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3497|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5343|M.marinum_M --------------------------------------------------
MUL_0086|M.ulcerans_Agy99 --------------------------------------------------
MAB_0986|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2783|M.avium_104 --------------------------------------------------
Mb0591|M.bovis_AF2122/97 GSQVIASEPVSEYVLAVAGKVITPATRNSAGFAAPAAVGSFAPVLDRLIA
Rv0576|M.tuberculosis_H37Rv GSQVIASEPVSEYVLAVAGKVITPATRNSAGFAAPAAVGSFAPVLDRLIA
TH_2906|M.thermoresistible__bu --------------------------------------------------
Mvan_4686|M.vanbaalenii_PYR-1 --------------
Mflv_2031|M.gilvum_PYR-GCK --------------
MSMEG_3497|M.smegmatis_MC2_155 --------------
MMAR_5343|M.marinum_M --------------
MUL_0086|M.ulcerans_Agy99 --------------
MAB_0986|M.abscessus_ATCC_1997 --------------
MAV_2783|M.avium_104 --------------
Mb0591|M.bovis_AF2122/97 FTGRQPTAGHVSAT
Rv0576|M.tuberculosis_H37Rv FTGRQPTAGHVSAT
TH_2906|M.thermoresistible__bu --------------