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VSSSAKVIYLRSYGDRDREDHHVVGAVLDATAALLCEFTFDDLTTRRIAEAAGVTHGDLCVYFRSTEAIV AEIYLGLLRDAPLTVDIEQSAQARVAALFNQLVMLPADHPGLAAACSRALISQEMSAHAIRRRIHAELHR RVCAVLRSEAWPEVTETLEFGLVGAMVQASAGITTFEATAGELACVVARLLPAGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4585 | - | - | 100% (195) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5158 | - | 1e-22 | 33.33% (177) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5714 | - | 3e-13 | 29.87% (154) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0790c | - | 1e-23 | 34.83% (178) | hypothetical protein Mb0790c |
| M. gilvum PYR-GCK | Mflv_1599 | - | 1e-22 | 32.77% (177) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0767c | - | 1e-23 | 34.83% (178) | hypothetical protein Rv0767c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1217c | - | 5e-25 | 33.16% (190) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4929 | - | 1e-22 | 33.15% (178) | hypothetical protein MMAR_4929 |
| M. avium 104 | MAV_0711 | - | 1e-23 | 34.27% (178) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5860 | - | 1e-24 | 34.36% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1258 | - | 3e-23 | 34.46% (177) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3114 | - | 4e-21 | 37.18% (156) | hypothetical protein MUL_3114 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1599|M.gilvum_PYR-GCK MSSDAVAALTPES------GHPPRNRRQEETFRKVLAAGLEMLRESSYAD
MSMEG_5860|M.smegmatis_MC2_155 MSSDAVAAVTPSG------GETPRNRRQEETFRKVLTAGIEMLRESSYAD
TH_1258|M.thermoresistible__bu VSSEAVSAITSEAGAT---GDTRRNRRQEETFRKVLAAGMETLRESSYAD
Mb0790c|M.bovis_AF2122/97 MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
Rv0767c|M.tuberculosis_H37Rv MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
MMAR_4929|M.marinum_M MSSDALVTVTDQQQHE--SGDRRRNRRQEETFRRVLAAGMDTLRASSYPD
MAV_0711|M.avium_104 MSSDALVTITSDAGGE--TGQPPRNRRQEETFRKVLAAGIETLREKSYSD
MAB_1217c|M.abscessus_ATCC_199 MSSEVVVPLTEET---------PRNRRQEETIRKIVTAGREMLGETTYAD
MUL_3114|M.ulcerans_Agy99 ---------------------------------------MDELRATSFAN
Mvan_4585|M.vanbaalenii_PYR-1 MSSSAKVIYLRSYG--------DRDREDHHVVGAVLDATAALLCEFTFDD
* :: :
Mflv_1599|M.gilvum_PYR-GCK LTVRAVAARAKVAPATAYTYFSSKNHLIAEIYLNLMQQVDYFTDVNDSTV
MSMEG_5860|M.smegmatis_MC2_155 LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDSMK
TH_1258|M.thermoresistible__bu LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDPMP
Mb0790c|M.bovis_AF2122/97 LTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMP
Rv0767c|M.tuberculosis_H37Rv LTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMP
MMAR_4929|M.marinum_M LTVRMVAARAGVSPATAYTYFSSKNHLIAEVYLDLVRKVPFFTDVNVAMR
MAV_0711|M.avium_104 LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDPMP
MAB_1217c|M.abscessus_ATCC_199 MTIRGVAARAKVAPATAYTYFSSKSHLVAEIYLDLIHEAPYFTDVNDTQA
MUL_3114|M.ulcerans_Agy99 LTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLLRDLPLHTDVNDTTK
Mvan_4585|M.vanbaalenii_PYR-1 LTTRRIAEAAGVTHGDLCVYFRSTEAIVAEIYLGLLRDAPLTVDIEQSAQ
:* * :* * *: . .** *.. ::* :** *::. .*:: .
Mflv_1599|M.gilvum_PYR-GCK TRVEKTLRSMALMVADEPEVAAACTTALLSG-NDATVRSVRERIGGEIHR
MSMEG_5860|M.smegmatis_MC2_155 TRVDKALRALTLVVADEPEVAAACTTALLGGGSDEAVRAVRDRIGAEIHK
TH_1258|M.thermoresistible__bu TRVEKALRSLALVVADEPEVAAACTTALMSG-NDPAVRKVRDRIGAEIHR
Mb0790c|M.bovis_AF2122/97 IRVTSSLRHLALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEIHR
Rv0767c|M.tuberculosis_H37Rv IRVTSSLRHLALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEIHR
MMAR_4929|M.marinum_M DRVVQALRHLALVVADEPEVGAACTAALLGGGADPAVRAVRDQIGAEIHR
MAV_0711|M.avium_104 TRVEQVLRHLALVVADEPEVSAACTTALLSGGADPAVRAARDRIGVEIHR
MAB_1217c|M.abscessus_ATCC_199 ARVTKTLRSLALVVADEPEIATGCTTALLSN-NDEAVRAVRDKIGLEIHR
MUL_3114|M.ulcerans_Agy99 TRVSATMRDMAMVVADEPELTAACGTALMAD--DPAVQPLRTQIGEEVAR
Mvan_4585|M.vanbaalenii_PYR-1 ARVAALFNQLVMLPADHPGLAAACSRALISQ--EMSAHAIRRRIHAELHR
** :. :.:: **.* : :.* **: : :.: * :* *: :
Mflv_1599|M.gilvum_PYR-GCK RIRAAVGPDPDPRTLAALEMTFFGALVNAGSGAFTYHQIADRLSYVVGLI
MSMEG_5860|M.smegmatis_MC2_155 RIRSAVGPDADPRTVSALEMTFFGALVNAGSGAFTYHQIADRLTYVVGLI
TH_1258|M.thermoresistible__bu RIRSAVGPGADPRLVSALEMTFFGALVHAGSGAFTYHQIADRLSYVVGLI
Mb0790c|M.bovis_AF2122/97 RITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADRLGYVVGLI
Rv0767c|M.tuberculosis_H37Rv RITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADRLGYVVGLI
MMAR_4929|M.marinum_M RIASAIGPGAQPGTIAALEMAFFGALVHAGSGEFTYHEVADRLADVAVLI
MAV_0711|M.avium_104 RITSAMGPDADPTTVSALEMSFFGALVQAGSGEFSYREIADRLAYVVRLI
MAB_1217c|M.abscessus_ATCC_199 RIRSAMGPDADPRVVSALEMTFFGALMHAGSGTFTYHQIADKLTFVVDLM
MUL_3114|M.ulcerans_Agy99 RIGAALGPGWPRSVKSTLQMTFSGALMTAR--FLSYEEIAGQLDEAVNLI
Mvan_4585|M.vanbaalenii_PYR-1 RVCAVLRSEAWPEVTETLEFGLVGAMVQASAGITTFEATAGELACVVARL
*: :.: . :*:: : **:: * ::. *..* .. :
Mflv_1599|M.gilvum_PYR-GCK VGDDQ-------------------
MSMEG_5860|M.smegmatis_MC2_155 LGEDR-------------------
TH_1258|M.thermoresistible__bu LGEDQHAPTPG---------GDE-
Mb0790c|M.bovis_AF2122/97 LAGANEPSTG----------GSE-
Rv0767c|M.tuberculosis_H37Rv LAGANEPSTG----------GSE-
MMAR_4929|M.marinum_M LVGAGQAAPGDDLAEPAAEAGEDA
MAV_0711|M.avium_104 LTGTTQASPET-------EAGDTR
MAB_1217c|M.abscessus_ATCC_199 LGKKE-------------------
MUL_3114|M.ulcerans_Agy99 LGAAVA------------------
Mvan_4585|M.vanbaalenii_PYR-1 LPAGS-------------------
: