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M. thermoresistible (build 8) TH_1258 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 2405285 - 2405917
length: 211

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1258-100% (211)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_0084-8e-3343.82% (178) putative transcriptional regulator
M. thermoresistible (build 8)TH_1635-2e-0728.57% (161) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0790c-1e-7778.53% (191) hypothetical protein Mb0790c
M. gilvum PYR-GCKMflv_1599-9e-8780.60% (201) TetR family transcriptional regulator
M. tuberculosis H37RvRv0767c-1e-7778.53% (191) hypothetical protein Rv0767c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1217c-9e-7870.65% (201) TetR family transcriptional regulator
M. marinum MMMAR_4929-1e-7672.95% (207) hypothetical protein MMAR_4929
M. avium 104MAV_0711-5e-8679.34% (213) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_5860-1e-8984.65% (202) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_0476-4e-4270.97% (124) hypothetical protein MUL_0476
M. vanbaalenii PYR-1Mvan_5158-4e-8578.61% (201) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1599|M.gilvum_PYR-GCK          MSSDAVAALTPES------GHPPRNRRQEETFRKVLAAGLEMLRESSYAD
Mvan_5158|M.vanbaalenii_PYR-1       MSNDAVAQLTEEP------GNPPRNRRQEETFRKVLAAGLEMLRESSYAD
MSMEG_5860|M.smegmatis_MC2_155      MSSDAVAAVTPSG------GETPRNRRQEETFRKVLTAGIEMLRESSYAD
TH_1258|M.thermoresistible__bu      VSSEAVSAITSEAG-A--TGDTRRNRRQEETFRKVLAAGMETLRESSYAD
MAB_1217c|M.abscessus_ATCC_199      MSSEVVVPLTEET---------PRNRRQEETIRKIVTAGREMLGETTYAD
MAV_0711|M.avium_104                MSSDALVTITSDAGGE--TGQPPRNRRQEETFRKVLAAGIETLREKSYSD
Mb0790c|M.bovis_AF2122/97           MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
Rv0767c|M.tuberculosis_H37Rv        MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
MMAR_4929|M.marinum_M               MSSDALVTVTDQQQHE--SGDRRRNRRQEETFRRVLAAGMDTLRASSYPD
MUL_0476|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_1599|M.gilvum_PYR-GCK          LTVRAVAARAKVAPATAYTYFSSKNHLIAEIYLNLMQQVDYFTDVNDSTV
Mvan_5158|M.vanbaalenii_PYR-1       LTVRAVAARAKVAPATAYTYFSSKNHLIAEIYLSLITKVDYFTDVNDSTA
MSMEG_5860|M.smegmatis_MC2_155      LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDSMK
TH_1258|M.thermoresistible__bu      LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDPMP
MAB_1217c|M.abscessus_ATCC_199      MTIRGVAARAKVAPATAYTYFSSKSHLVAEIYLDLIHEAPYFTDVNDTQA
MAV_0711|M.avium_104                LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDPMP
Mb0790c|M.bovis_AF2122/97           LTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMP
Rv0767c|M.tuberculosis_H37Rv        LTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMP
MMAR_4929|M.marinum_M               LTVRMVAARAGVSPATAYTYFSSKNHLIAEVYLDLVRKVPFFTDVNVAMR
MUL_0476|M.ulcerans_Agy99           -----------------------------------MRKVPFFTDVNVAMR
                                                                       : :.  .**** .  

Mflv_1599|M.gilvum_PYR-GCK          TRVEKTLRSMALMVADEPEVAAACTTALLSG-NDATVRSVRERIGGEIHR
Mvan_5158|M.vanbaalenii_PYR-1       VRVEKTLRSMALMIADEPEVAAACTTALLSG-NDAAVRTVRERIGAEIHR
MSMEG_5860|M.smegmatis_MC2_155      TRVDKALRALTLVVADEPEVAAACTTALLGGGSDEAVRAVRDRIGAEIHK
TH_1258|M.thermoresistible__bu      TRVEKALRSLALVVADEPEVAAACTTALMSG-NDPAVRKVRDRIGAEIHR
MAB_1217c|M.abscessus_ATCC_199      ARVTKTLRSLALVVADEPEIATGCTTALLSN-NDEAVRAVRDKIGLEIHR
MAV_0711|M.avium_104                TRVEQVLRHLALVVADEPEVSAACTTALLSGGADPAVRAARDRIGVEIHR
Mb0790c|M.bovis_AF2122/97           IRVTSSLRHLALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEIHR
Rv0767c|M.tuberculosis_H37Rv        IRVTSSLRHLALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEIHR
MMAR_4929|M.marinum_M               DRVVQALRHLALVVADEPEVGAACTAALLGGGADPAVRAVRDQIGAEIHR
MUL_0476|M.ulcerans_Agy99           DRVVQALRHLALVVADEPEVGAACTAALLGGGADPAVRAVRDQIGAEIHR
                                     ** . ** ::*::*****:.:.**:**:..  * :** .*::** ***:

Mflv_1599|M.gilvum_PYR-GCK          RIRAAVGPDPDPRTLAALEMTFFGALVNAGSGAFTYHQIADRLSYVVGLI
Mvan_5158|M.vanbaalenii_PYR-1       RIRAAVGPDPDPRTLAALEMTFFGALVNAGSGAFTYHQIADRLSYVVGLI
MSMEG_5860|M.smegmatis_MC2_155      RIRSAVGPDADPRTVSALEMTFFGALVNAGSGAFTYHQIADRLTYVVGLI
TH_1258|M.thermoresistible__bu      RIRSAVGPGADPRLVSALEMTFFGALVHAGSGAFTYHQIADRLSYVVGLI
MAB_1217c|M.abscessus_ATCC_199      RIRSAMGPDADPRVVSALEMTFFGALMHAGSGTFTYHQIADKLTFVVDLM
MAV_0711|M.avium_104                RITSAMGPDADPTTVSALEMSFFGALVQAGSGEFSYREIADRLAYVVRLI
Mb0790c|M.bovis_AF2122/97           RITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADRLGYVVGLI
Rv0767c|M.tuberculosis_H37Rv        RITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADRLGYVVGLI
MMAR_4929|M.marinum_M               RIASAIGPGAQPGTIAALEMAFFGALVHAGSGEFTYHEVADRLADVAVLI
MUL_0476|M.ulcerans_Agy99           RIASAIGPGAQPGTIAALEMAFFGALVHAGSGKFTYHEVADRLADVAVLI
                                    ** :*:**..:*  : ****:*****::**** *:*:::**:*  *. *:

Mflv_1599|M.gilvum_PYR-GCK          V-GDDQ------------------
Mvan_5158|M.vanbaalenii_PYR-1       V-GDDK------------------
MSMEG_5860|M.smegmatis_MC2_155      L-GEDR------------------
TH_1258|M.thermoresistible__bu      L-GEDQHAPTPGGDE---------
MAB_1217c|M.abscessus_ATCC_199      L-GKKE------------------
MAV_0711|M.avium_104                LTGTTQASPETEAGDTR-------
Mb0790c|M.bovis_AF2122/97           LAGANEPSTG----------GSE-
Rv0767c|M.tuberculosis_H37Rv        LAGANEPSTG----------GSE-
MMAR_4929|M.marinum_M               LVGAGQAAPGDDLAEPAAEAGEDA
MUL_0476|M.ulcerans_Agy99           LVGAGQAAPGDDLAEPAAEAGEDA
                                    : *  .