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VSSDALVTVTDQQQHESGDRRRNRRQEETFRRVLAAGMDTLRASSYPDLTVRMVAARAGVSPATAYTYFS SKNHLIAEVYLDLVRKVPFFTDVNVAMRDRVVQALRHLALVVADEPEVGAACTAALLGGGADPAVRAVRD QIGAEIHRRIASAIGPGAQPGTIAALEMAFFGALVHAGSGEFTYHEVADRLADVAVLILVGAGQAAPGDD LAEPAAEAGEDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4929 | - | - | 100% (222) | hypothetical protein MMAR_4929 |
| M. marinum M | MMAR_2639 | - | 4e-43 | 51.61% (186) | hypothetical protein MMAR_2639 |
| M. marinum M | MMAR_5193 | - | 1e-06 | 30.71% (140) | hypothetical protein MMAR_5193 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0790c | - | 1e-80 | 74.76% (210) | hypothetical protein Mb0790c |
| M. gilvum PYR-GCK | Mflv_1599 | - | 2e-66 | 65.83% (199) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0767c | - | 1e-80 | 74.76% (210) | hypothetical protein Rv0767c |
| M. leprae Br4923 | MLBr_00717 | - | 2e-05 | 26.28% (137) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1217c | - | 2e-61 | 58.79% (199) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0711 | - | 5e-82 | 74.88% (207) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5860 | - | 8e-75 | 72.36% (199) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1258 | - | 9e-77 | 72.95% (207) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0476 | - | 1e-73 | 99.28% (139) | hypothetical protein MUL_0476 |
| M. vanbaalenii PYR-1 | Mvan_5158 | - | 6e-67 | 65.83% (199) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4929|M.marinum_M MSSDALVTVTDQQQHE--SGDRRRNRRQEETFRRVLAAGMDTLRASSYPD
MUL_0476|M.ulcerans_Agy99 --------------------------------------------------
Mb0790c|M.bovis_AF2122/97 MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
Rv0767c|M.tuberculosis_H37Rv MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
Mflv_1599|M.gilvum_PYR-GCK MSSDAVAALTPES------GHPPRNRRQEETFRKVLAAGLEMLRESSYAD
Mvan_5158|M.vanbaalenii_PYR-1 MSNDAVAQLTEEP------GNPPRNRRQEETFRKVLAAGLEMLRESSYAD
MSMEG_5860|M.smegmatis_MC2_155 MSSDAVAAVTPSG------GETPRNRRQEETFRKVLTAGIEMLRESSYAD
TH_1258|M.thermoresistible__bu VSSEAVSAITSEAG-A--TGDTRRNRRQEETFRKVLAAGMETLRESSYAD
MAB_1217c|M.abscessus_ATCC_199 MSSEVVVPLTEET---------PRNRRQEETIRKIVTAGREMLGETTYAD
MAV_0711|M.avium_104 MSSDALVTITSDAGGE--TGQPPRNRRQEETFRKVLAAGIETLREKSYSD
MLBr_00717|M.leprae_Br4923 --------MTTAR----------RRLSPEDRRAELLALGAEVFGKRPYDE
MMAR_4929|M.marinum_M LTVRMVAARAGVSPATAYTYFSSKNHLIAEVYLDLVRKVPFFTDVNVAMR
MUL_0476|M.ulcerans_Agy99 -----------------------------------MRKVPFFTDVNVAMR
Mb0790c|M.bovis_AF2122/97 LTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMP
Rv0767c|M.tuberculosis_H37Rv LTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMP
Mflv_1599|M.gilvum_PYR-GCK LTVRAVAARAKVAPATAYTYFSSKNHLIAEIYLNLMQQVDYFTDVNDSTV
Mvan_5158|M.vanbaalenii_PYR-1 LTVRAVAARAKVAPATAYTYFSSKNHLIAEIYLSLITKVDYFTDVNDSTA
MSMEG_5860|M.smegmatis_MC2_155 LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDSMK
TH_1258|M.thermoresistible__bu LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDPMP
MAB_1217c|M.abscessus_ATCC_199 MTIRGVAARAKVAPATAYTYFSSKSHLVAEIYLDLIHEAPYFTDVNDTQA
MAV_0711|M.avium_104 LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDPMP
MLBr_00717|M.leprae_Br4923 VRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAG
. *:: .
MMAR_4929|M.marinum_M DRVVQALRH--LALVVADEPEVGAACTAALLGGGADPAVRAVRDQIGAEI
MUL_0476|M.ulcerans_Agy99 DRVVQALRH--LALVVADEPEVGAACTAALLGGGADPAVRAVRDQIGAEI
Mb0790c|M.bovis_AF2122/97 IRVTSSLRH--LALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEI
Rv0767c|M.tuberculosis_H37Rv IRVTSSLRH--LALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEI
Mflv_1599|M.gilvum_PYR-GCK TRVEKTLRS--MALMVADEPEVAAACTTALLSG-NDATVRSVRERIGGEI
Mvan_5158|M.vanbaalenii_PYR-1 VRVEKTLRS--MALMIADEPEVAAACTTALLSG-NDAAVRTVRERIGAEI
MSMEG_5860|M.smegmatis_MC2_155 TRVDKALRA--LTLVVADEPEVAAACTTALLGGGSDEAVRAVRDRIGAEI
TH_1258|M.thermoresistible__bu TRVEKALRS--LALVVADEPEVAAACTTALMSG-NDPAVRKVRDRIGAEI
MAB_1217c|M.abscessus_ATCC_199 ARVTKTLRS--LALVVADEPEIATGCTTALLSN-NDEAVRAVRDKIGLEI
MAV_0711|M.avium_104 TRVEQVLRH--LALVVADEPEVSAACTTALLSGGADPAVRAARDRIGVEI
MLBr_00717|M.leprae_Br4923 LTMFEEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQ
: . :* :: : .: : :. :: : . * .: :. .
MMAR_4929|M.marinum_M HRRIASAIG------PGA--QPGTIAALEMAFFGALVH----AGSGEFTY
MUL_0476|M.ulcerans_Agy99 HRRIASAIG------PGA--QPGTIAALEMAFFGALVH----AGSGKFTY
Mb0790c|M.bovis_AF2122/97 HRRITSAIG------PGA--DPGTVFALEMAFFGALVQ----AGSGTFTY
Rv0767c|M.tuberculosis_H37Rv HRRITSAIG------PGA--DPGTVFALEMAFFGALVQ----AGSGTFTY
Mflv_1599|M.gilvum_PYR-GCK HRRIRAAVG------PDP--DPRTLAALEMTFFGALVN----AGSGAFTY
Mvan_5158|M.vanbaalenii_PYR-1 HRRIRAAVG------PDP--DPRTLAALEMTFFGALVN----AGSGAFTY
MSMEG_5860|M.smegmatis_MC2_155 HKRIRSAVG------PDA--DPRTVSALEMTFFGALVN----AGSGAFTY
TH_1258|M.thermoresistible__bu HRRIRSAVG------PGA--DPRLVSALEMTFFGALVH----AGSGAFTY
MAB_1217c|M.abscessus_ATCC_199 HRRIRSAMG------PDA--DPRVVSALEMTFFGALMH----AGSGTFTY
MAV_0711|M.avium_104 HRRITSAMG------PDA--DPTTVSALEMSFFGALVQ----AGSGEFSY
MLBr_00717|M.leprae_Br4923 MEHIMSRIGDVVSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDP
.:* : :* * . .* *.: ..* * . . :
MMAR_4929|M.marinum_M HEVADRLADVAVLILVGAGQAAPGDDLAEPAAEAGEDA---
MUL_0476|M.ulcerans_Agy99 HEVADRLADVAVLILVGAGQAAPGDDLAEPAAEAGEDA---
Mb0790c|M.bovis_AF2122/97 HEIADRLGYVVGLILAGANEPSTG----------GSE----
Rv0767c|M.tuberculosis_H37Rv HEIADRLGYVVGLILAGANEPSTG----------GSE----
Mflv_1599|M.gilvum_PYR-GCK HQIADRLSYVVGLIV-GDDQ---------------------
Mvan_5158|M.vanbaalenii_PYR-1 HQIADRLSYVVGLIV-GDDK---------------------
MSMEG_5860|M.smegmatis_MC2_155 HQIADRLTYVVGLIL-GEDR---------------------
TH_1258|M.thermoresistible__bu HQIADRLSYVVGLIL-GEDQHAPTPGGDE------------
MAB_1217c|M.abscessus_ATCC_199 HQIADKLTFVVDLML-GKKE---------------------
MAV_0711|M.avium_104 REIADRLAYVVRLILTGTTQASPETEAGDTR----------
MLBr_00717|M.leprae_Br4923 STDADRLADSCAHALLDAIARVPEISKELADAMAIARQPPQ
**:* : .