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NDSVDNPFFARLWTLMSSREPESLRRLRRENLAGLTGRVLEVGAGTGTNFEFYPATVTEVVAVEPEHRLA TLAQDAAARAAVPITVTTDTVEEFTDAEPFDAVVCSLVLCSVDKPEDVVAELLSMLKPGGQLRYLEHIAA EGGRARLQRFADATVWPRLLGNCHTHRHTEETIVGAGFRVRDARREWTFPRWVPLPVAEFAIGVAVKP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4571 | - | - | 100% (209) | methyltransferase type 12 |
| M. vanbaalenii PYR-1 | Mvan_2948 | - | 2e-10 | 31.20% (125) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_4887 | - | 2e-06 | 29.75% (121) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1178 | - | 3e-75 | 65.35% (202) | hypothetical protein Mb1178 |
| M. gilvum PYR-GCK | Mflv_2133 | - | 8e-99 | 81.90% (210) | methyltransferase type 12 |
| M. tuberculosis H37Rv | Rv1147 | - | 3e-75 | 65.35% (202) | hypothetical protein Rv1147 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1291 | - | 3e-59 | 52.40% (208) | hypothetical protein MAB_1291 |
| M. marinum M | MMAR_4303 | - | 2e-74 | 62.62% (206) | hypothetical protein MMAR_4303 |
| M. avium 104 | MAV_1288 | - | 3e-72 | 62.93% (205) | hypothetical protein MAV_1288 |
| M. smegmatis MC2 155 | MSMEG_5176 | - | 9e-83 | 68.60% (207) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_1988 | - | 3e-57 | 67.97% (153) | methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_0991 | - | 1e-74 | 62.62% (206) | hypothetical protein MUL_0991 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4571|M.vanbaalenii_PYR-1 -------MNDSVDNPFFARLWTLMSSREPESLRRLRRENLAGLTGRVLEV
Mflv_2133|M.gilvum_PYR-GCK -------MSDVVDNPFFARLWTAMSSREPESLRRLRRDNLAGLTGRVLEV
MSMEG_5176|M.smegmatis_MC2_155 MPPTDAAQPEPVDNPFFAWLWKTLSTHETESVRRMRAENLAGLSGRVLEV
TH_1988|M.thermoresistible__bu -------MTSTVDNPFFARMWTWLSSHEPEAMRQRREQLLAGLSGRVLEV
Mb1178|M.bovis_AF2122/97 MTSGAAASASRVDHPLFARIWPVVAAHEAEAIRALRRENLAGLSGRVLEV
Rv1147|M.tuberculosis_H37Rv MTSGAAASASRVDHPLFARIWPVVAAHEAEAIRALRRENLAGLSGRVLEV
MMAR_4303|M.marinum_M MTS----LAKNIDHPFFARIWPFIVAHEAEPVRALRRENLAGLSGRVLEI
MUL_0991|M.ulcerans_Agy99 MTS----LAKNIDHPFFARIWPFIVAHEAEPVRALRRENLAGLSGRVLEI
MAV_1288|M.avium_104 MTT------VVVDNPFFARIWPVVATHETAAVRALRRENVAGLTGRVLEV
MAB_1291|M.abscessus_ATCC_1997 MTT-----PVSFDNRFFSATWSAIARREPQEIKELRAENLRGLTGHVLEV
.*: :*: * : :*. :: * : : **:*:***:
Mvan_4571|M.vanbaalenii_PYR-1 GAGTGTNFEFYPATVTEVVAVEPEHRLATLAQDAAARAAVPITVTTDTVE
Mflv_2133|M.gilvum_PYR-GCK GAGTGTNFEFYPSTVTEVVAVEPERRLAVLAEQAAAGAAVPVTVSTDTVE
MSMEG_5176|M.smegmatis_MC2_155 GAGTGTNFEFYPSTVDEVVAIEPERRLADVARQAAAKAPVPVSVTGDTIE
TH_1988|M.thermoresistible__bu GAGTGTNFAFYPPGVTEVVAVEPEQRLVAVVRQAAAEAPVPVTVRAETVE
Mb1178|M.bovis_AF2122/97 GAGVGTNFAYYPVAVEQVIAMEPEPRLAAKARIAAADAPVPIVVTDKTVE
Rv1147|M.tuberculosis_H37Rv GAGVGTNFAYYPVAVEQVIAMEPEPRLAAKARIAAADAPVPIVVTDKTVE
MMAR_4303|M.marinum_M GAGMGTNFAFYPQTVTEVVAVEPEPHLALRARAAGEDAPIPVTVTADTAE
MUL_0991|M.ulcerans_Agy99 GAGMGTNFAFYPQTVTEVVAVEPEPHLALRARAAGEDAPIPVTVTADTAE
MAV_1288|M.avium_104 GAGIGTNFPLYPETVDEVIAVEPEPRLADRARAAAQVVPVRVVVTGETAE
MAB_1291|M.abscessus_ATCC_1997 GAGIGSNFLLYPNTVTAVTALEPESRLRPQAEDAAAGAAIPVTVTAGVFE
*** *:** ** * * *:*** :* .. *. ..: : * . *
Mvan_4571|M.vanbaalenii_PYR-1 EFTDA--EPFDAVVCSLVLCSVDKPEDVVAELLSMLKPGGQLRYLEHIAA
Mflv_2133|M.gilvum_PYR-GCK QFADA--KPFDAVVCSLVLCSVDDPEQVVSQLFSVLKPGGELRYLEHVAS
MSMEG_5176|M.smegmatis_MC2_155 TFASA--QPFDAVVCSLVLCSVDDPEQVVGQLYSLLRPGGELRYLEHVAG
TH_1988|M.thermoresistible__bu NFDSS--EPFDAVVCTLVLCSVDDPAGVVRQLFSLLRPGGELRYLEHIAS
Mb1178|M.bovis_AF2122/97 EFRDT--ETFDAVVCSLVLCSVSDPGAVLAHLRSLLRRGGELRYLEHVAS
Rv1147|M.tuberculosis_H37Rv EFRDT--ETFDAVVCSLVLCSVSDPGAVLAHLRSLLRRGGELRYLEHVAS
MMAR_4303|M.marinum_M QFSDQ--DPFDAVVCSLVLCSVTDQLGVLQHLRSLLRPGGELRYLEHIAS
MUL_0991|M.ulcerans_Agy99 QFSDQ--DPFDAVVCSLVLCSVTDQLGVLQHLRSLLRPGGELRYLEHIAS
MAV_1288|M.avium_104 AVGGD--EPFDAVVCSLVLCSVRDPQNVLRRLYSLLRPGGQLRYLEHIAS
MAB_1291|M.abscessus_ATCC_1997 DLAVTGEDRFDAVVCSLVLCSVGDPDRAAAQAFEVLKPGGEVRFFEHVAH
. . ******:****** . . . .:*: **::*::**:*
Mvan_4571|M.vanbaalenii_PYR-1 EGG-RARLQRFADATVWPRLLGNCHTHRHTEETIVGAGFRVRDARREWTF
Mflv_2133|M.gilvum_PYR-GCK DGAARGRLQRFADATFWPRLLGNCHTHRRTEDTITRAGFRVDDARREWTF
MSMEG_5176|M.smegmatis_MC2_155 TGF-QARLQRLADATVWPKLFGGCHTHRHTEQVIASSGFGVRGRRREQVL
TH_1988|M.thermoresistible__bu AGA-RGRLQRFADXR-----------------------------------
Mb1178|M.bovis_AF2122/97 AGA-RGRVQRFVDATFWPRLAGNCHTHRHTERAILDAGFVVDSSRREWAF
Rv1147|M.tuberculosis_H37Rv AGA-RGRVQRFVDATFWPRLAGNCHTHRHTERAILDAGFVVDSSRREWAF
MMAR_4303|M.marinum_M AGA-RGRLQQFVDATFWPRIAGNCHTHRDTERVIKAAGFDVESTRREWTL
MUL_0991|M.ulcerans_Agy99 AGA-RGRLQQFVDATFWPRIAGNCHTHRDTERVIKAAGFDVESTRREWTL
MAV_1288|M.avium_104 AGA-RGRFQRFVDATLWPRLFGNCHTHRDTERSIVEAGFDVDASRREWTL
MAB_1291|M.abscessus_ATCC_1997 DGA-LGLVQRAVDATFWPRLFGNCHTHRDTLAAIERAGFTIEERRDDWLK
* . .*: .*
Mvan_4571|M.vanbaalenii_PYR-1 PRWVPLPVAEFAIGVAVKP-
Mflv_2133|M.gilvum_PYR-GCK PAWVPVPVAEFAIGVARRP-
MSMEG_5176|M.smegmatis_MC2_155 PAWVPVPTTEFAIGRAVRP-
TH_1988|M.thermoresistible__bu --------------------
Mb1178|M.bovis_AF2122/97 PAWVPLPVSELALGRAHRT-
Rv1147|M.tuberculosis_H37Rv PAWVPLPVSELALGRAHRT-
MMAR_4303|M.marinum_M PTWAPVPVAELVLGRARRP-
MUL_0991|M.ulcerans_Agy99 PTWAPVPVAELVLGRARRP-
MAV_1288|M.avium_104 PAWSPMPVSELLLGRAHRPA
MAB_1291|M.abscessus_ATCC_1997 VMGIPMPSSSIVIGRAVKPA