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SKLIVVAGALIEGGALLVAQRDRPPELAGLWELPGGKVAPGESDEAALVRELNEELGVDVTVGARVGADI ALSAAMCLRAYAVTRTRGVVAPHDHRALRWIRTEEIETLPWVPADRAWLPDLTRLLAGADHARASGAAAR RGNQPPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4548 | - | - | 100% (148) | NUDIX hydrolase |
| M. vanbaalenii PYR-1 | Mvan_6062 | - | 6e-06 | 30.00% (130) | NUDIX hydrolase |
| M. vanbaalenii PYR-1 | Mvan_2138 | - | 6e-06 | 27.44% (164) | NUDIX hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1192 | mutT2 | 4e-36 | 58.14% (129) | 7,8-dihydro-8-oxoguanine-triphosphatase |
| M. gilvum PYR-GCK | Mflv_2154 | - | 4e-56 | 79.84% (129) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv1160 | mutT2 | 4e-36 | 58.14% (129) | 7,8-dihydro-8-oxoguanine-triphosphatase |
| M. leprae Br4923 | MLBr_01682 | - | 9e-05 | 52.78% (36) | hypothetical protein MLBr_01682 |
| M. abscessus ATCC 19977 | MAB_1308 | - | 5e-33 | 53.54% (127) | mutator protein MutT2/NUDIX hydrolase |
| M. marinum M | MMAR_4290 | mutT2 | 9e-38 | 59.69% (129) | mutator protein MutT2 |
| M. avium 104 | MAV_1301 | - | 4e-39 | 63.49% (126) | hydrolase, NUDIX family protein |
| M. smegmatis MC2 155 | MSMEG_5148 | - | 9e-48 | 70.54% (129) | CTP pyrophosphohydrolase |
| M. thermoresistible (build 8) | TH_0645 | mutT2 | 3e-44 | 66.94% (124) | PROBABLE MUTATOR PROTEIN MUTT |
| M. ulcerans Agy99 | MUL_1008 | mutT2 | 2e-36 | 58.91% (129) | mutator protein MutT2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1192|M.bovis_AF2122/97 --------------------------------------------------
Rv1160|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1301|M.avium_104 --------------------------------------------------
MMAR_4290|M.marinum_M --------------------------------------------------
MUL_1008|M.ulcerans_Agy99 --------------------------------------------------
MAB_1308|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4548|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2154|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5148|M.smegmatis_MC2_155 --------------------------------------------------
TH_0645|M.thermoresistible__bu --------------------------------------------------
MLBr_01682|M.leprae_Br4923 MAIWNSSCQWPKSQIVYAAGAVLWRPGNSDPAVEIAVIHRPRYDDWSLSK
Mb1192|M.bovis_AF2122/97 --------------------------------------------------
Rv1160|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1301|M.avium_104 --------------------------------------------------
MMAR_4290|M.marinum_M --------------------------------------MRAIMFGLSKPA
MUL_1008|M.ulcerans_Agy99 --------------------------------------------------
MAB_1308|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4548|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2154|M.gilvum_PYR-GCK -------------------------------MVFALGVLADAPDRVDAVE
MSMEG_5148|M.smegmatis_MC2_155 --------------------------------------------------
TH_0645|M.thermoresistible__bu --------------------------------------------------
MLBr_01682|M.leprae_Br4923 GKVDPGETAPMAAVREVFEETGHHATLGARLVVVNYPIGQHVKKVYYWAA
Mb1192|M.bovis_AF2122/97 --------------------------------------------MLN---
Rv1160|M.tuberculosis_H37Rv --------------------------------------------MLN---
MAV_1301|M.avium_104 ----------------------------------MRADGIPSLAMPT---
MMAR_4290|M.marinum_M WRAVKAAVAQGWGVLGQHGFGRIAVRRIWEVALPGRLGEIPSLAMPNQPN
MUL_1008|M.ulcerans_Agy99 --------------------------------------------MPNQPN
MAB_1308|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4548|M.vanbaalenii_PYR-1 --------------------------------------------MSK---
Mflv_2154|M.gilvum_PYR-GCK KRGELDRSSQRPVGALPTVELGQNGVHLFVSQYSHAFDGIPSSPMSN---
MSMEG_5148|M.smegmatis_MC2_155 --------------------------------------------MTK---
TH_0645|M.thermoresistible__bu ----------------------------------------MTQIPQP---
MLBr_01682|M.leprae_Br4923 RSIEGQFVPGSEVDELLWLPVVDAMKKLDYVQDRKVLRQFAKQPAYTRTV
Mb1192|M.bovis_AF2122/97 QIVVAGAIVRGCTVLVAQRVRPPELAG--RWELPGGKVAAGETERAALAR
Rv1160|M.tuberculosis_H37Rv QIVVAGAIVRGCTVLVAQRVRPPELAG--RWELPGGKVAAGETERAALAR
MAV_1301|M.avium_104 QIVVAGALIRGSRLLVAQRARPPELAG--RWELPGGKVAPGETERDALAR
MMAR_4290|M.marinum_M QIVVAGAIIRGATVLVAQRARPPELAG--RWELPGGKVAGGETEPAALAR
MUL_1008|M.ulcerans_Agy99 QIVVAGAFICGATVLVAQRVRPPELAG--RWELPGGKVAGGETEPAALAR
MAB_1308|M.abscessus_ATCC_1997 --MVAGAVIDGDKLLIAQRAKPAELAG--QWELPGGKVADGESEPQALVR
Mvan_4548|M.vanbaalenii_PYR-1 LIVVAGALIEGGALLVAQRDRPPELAG--LWELPGGKVAPGESDEAALVR
Mflv_2154|M.gilvum_PYR-GCK LIVVAGALIEHGALLVAQRARPPELAG--LWELPGGKVTPPESDESALAR
MSMEG_5148|M.smegmatis_MC2_155 QIVVAGALISRGTLLVAQRDRPAELAG--LWELPGGKVTPGESDADALAR
TH_0645|M.thermoresistible__bu QIVVAGALIADAALLVAQRNRPPELAG--RWELPGGKVAPGETEAEALVR
MLBr_01682|M.leprae_Br4923 LIVRHGTAGRKSRLSEDDTKRPLDKQGRAQAEALIGQLLAFGATDVYAAD
: *: : : :* : * * *:: : .
Mb1192|M.bovis_AF2122/97 ELAEELGLEVADLAVGDRVGDDIALNGTTTLRAYRVHLLG---GEPRARD
Rv1160|M.tuberculosis_H37Rv ELAEELGLEVADLAVGDRVGDDIALNGTTTLRAYRVHLLG---GEPRARD
MAV_1301|M.avium_104 ELAEELGLRVGDIAVGDRLGGDIAVDGGMTLRAYRVRLLR---GRPDARD
MMAR_4290|M.marinum_M ELVEELGLGVDDVAVGERLGADVVLDEKTVLRAYRVRLLR---GHPCARD
MUL_1008|M.ulcerans_Agy99 ELVEELGLGVDDVAVGERLGADVVPDEKTVLRAYRVRLLR---GHPCARD
MAB_1308|M.abscessus_ATCC_1997 ELREELGIEV---EVGARLGEDVVVG-NLVLRAYSARLHPQHPGSPHPHE
Mvan_4548|M.vanbaalenii_PYR-1 ELNEELGVDV---TVGARVGADIALSAAMCLRAYAVTRTR---GVVAPHD
Mflv_2154|M.gilvum_PYR-GCK ELNEELGIDV---TVGPRIGADVALSATTTLRAYVVTRTR---GAVTAHD
MSMEG_5148|M.smegmatis_MC2_155 ELREELGVDV---AVGERLGADVALNDAMTLRAYRVTLRS---GSPHPHD
TH_0645|M.thermoresistible__bu ELKEELGVDV---EVGARLGVEVALTESMVLRAFRVHHRG---GSPSPND
MLBr_01682|M.leprae_Br4923 QLHCHQTVEPLAAELGVPIHNEPSLTKEAFAKNPKRGLHR-VLRIAAQSG
:* . : :* : : :
Mb1192|M.bovis_AF2122/97 HRALCWVTAAELHDVDWVPADRGWIADLARTLNGSAADVHRRC-------
Rv1160|M.tuberculosis_H37Rv HRALCWVTAAELHDVDWVPADRGWIADLARTLNGSAADVHRRC-------
MAV_1301|M.avium_104 HRALRWITAAQLHDLDWVPADRGWLGDLARVL------------------
MMAR_4290|M.marinum_M HRALRWVTADQLDDVDWVPADRCWLADLDRALRPAPPPG-----------
MUL_1008|M.ulcerans_Agy99 HRALRWVTVDQLDDVDWVPADRCWLADLDRALRPAPPTG-----------
MAB_1308|M.abscessus_ATCC_1997 HLALRWVTAGELDAVEWVAADGGWIPALKQALVGTRPV------------
Mvan_4548|M.vanbaalenii_PYR-1 HRALRWIRTEEIETLPWVPADRAWLPDLTRLLAGADHARASGAAARRGNQ
Mflv_2154|M.gilvum_PYR-GCK HRALRWVRADEIPSLPWVPADRAWLPDLVGLLAGNNLTQSGSGTDTDG--
MSMEG_5148|M.smegmatis_MC2_155 HRALRWVGADEIDGLAWVPADRAWVPDLVAALSGR---------------
TH_0645|M.thermoresistible__bu HRALRWVTAAELHDLDWVPADRAWIPELTALLSAR---------------
MLBr_01682|M.leprae_Br4923 TPVICLQGKIIPDLIAWWCERDGVRPKKSHNYKGSTWVLSLLAGQLVAVD
.: : *
Mb1192|M.bovis_AF2122/97 ------------
Rv1160|M.tuberculosis_H37Rv ------------
MAV_1301|M.avium_104 ------------
MMAR_4290|M.marinum_M ------------
MUL_1008|M.ulcerans_Agy99 ------------
MAB_1308|M.abscessus_ATCC_1997 ------------
Mvan_4548|M.vanbaalenii_PYR-1 PPA---------
Mflv_2154|M.gilvum_PYR-GCK ------------
MSMEG_5148|M.smegmatis_MC2_155 ------------
TH_0645|M.thermoresistible__bu ------------
MLBr_01682|M.leprae_Br4923 HVGSTLAANVQP