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TNRSGTRSSVGLLDIAKQVPGLLKDAPTIVRGVVTGFGARPTAKTSIGKVFQDRAAQYPNNVFLKFEDRE ITYREANDTVNRYAAVLAAKGVGHGDVVGIMMRNSPEPILLMLAAVKCGAISGMLNYHQRDEVLKHSLGL LSAAVVVAETEFVEAITESGADTDGLITLDELKQLAETAPTTNPATTSAVLAKDKAFYIFTSGTTGMPKA SVMTHYRWLRALAGFGGLGLRLNSSDTLYCCLPLYHNNALTVALSSVINSGATLALGKSFSASRFWDDVI RYDATAFVYIGEICTYLLNQPEKPTDRRHKVRVICGNGLRPAIWDAFTERFGIKRVCEFYAASEGNTAFV NVLNIDKTTGICPTPIAFVEYDENTGEPVRDEQGRVRRVKKGEPGLLLSKVSNYQPFDGYTDKKESEKKL VRDAFKEGDVWFNTGDLMRAQGLGHAAFTDRLGDTFRWKGENVATTEVEAAVSTHHQIEECTVFGVEVPD TGGRAGMVAIQLKEGHELDGQSLAKAVFEKLPSYAVPLFVRVVQELAHTSTFKSQKGDLRKEGYGGSSGE GGDDDVKIDDPLYVLSGREEGYVPFYDEYPHEVREGKKPK*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4510 | - | - | 100% (601) | acyl-CoA synthetase |
M. vanbaalenii PYR-1 | Mvan_3301 | - | 1e-40 | 25.98% (535) | acyl-CoA synthetase |
M. vanbaalenii PYR-1 | Mvan_5208 | - | 1e-37 | 28.85% (468) | acyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1238 | fadD6 | 0.0 | 67.50% (600) | acyl-CoA synthetase |
M. gilvum PYR-GCK | Mflv_2185 | - | 0.0 | 88.17% (600) | acyl-CoA synthetase |
M. tuberculosis H37Rv | Rv1206 | fadD6 | 0.0 | 67.50% (600) | acyl-CoA synthetase |
M. leprae Br4923 | MLBr_01346 | - | 8e-37 | 26.07% (537) | acyl-CoA synthetase |
M. abscessus ATCC 19977 | MAB_1342 | - | 0.0 | 62.81% (597) | acyl-CoA synthetase |
M. marinum M | MMAR_4232 | fadD6 | 0.0 | 68.90% (598) | fatty-acid-CoA ligase FadD6 |
M. avium 104 | MAV_1351 | - | 0.0 | 68.46% (596) | acyl-CoA synthetase |
M. smegmatis MC2 155 | MSMEG_5086 | - | 0.0 | 76.71% (601) | acyl-CoA synthetase |
M. thermoresistible (build 8) | TH_2434 | - | 0.0 | 71.40% (598) | PUTATIVE very-long-chain acyl-CoA synthetase |
M. ulcerans Agy99 | MUL_0957 | fadD6 | 0.0 | 68.73% (598) | acyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1238|M.bovis_AF2122/97 -------------------------------------------------- Rv1206|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4232|M.marinum_M -------------------------------------------------- MUL_0957|M.ulcerans_Agy99 -------------------------------------------------- MAV_1351|M.avium_104 -------------------------------------------------- Mvan_4510|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2185|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5086|M.smegmatis_MC2_155 -------------------------------------------------- TH_2434|M.thermoresistible__bu -------------------------------------------------- MAB_1342|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01346|M.leprae_Br4923 MDLNFSIVTRPVERLVATAQNGLEVLRLGGLETGSFPSPSQIVESVPMYK Mb1238|M.bovis_AF2122/97 -------------------------------------------------- Rv1206|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4232|M.marinum_M -------------------------------------------------- MUL_0957|M.ulcerans_Agy99 -------------------------------------------------- MAV_1351|M.avium_104 -------------------------------------------------- Mvan_4510|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2185|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5086|M.smegmatis_MC2_155 -------------------------------------------------- TH_2434|M.thermoresistible__bu -------------------------------------------------- MAB_1342|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01346|M.leprae_Br4923 LRRYFPPGNRPGQPLLGAPVLMVHPMMMSADMWDVTREEGAVGILHVRGL Mb1238|M.bovis_AF2122/97 -------------------------------------------------- Rv1206|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4232|M.marinum_M -------------------------------------------------- MUL_0957|M.ulcerans_Agy99 -------------------------------------------------- MAV_1351|M.avium_104 -------------------------------------------------- Mvan_4510|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2185|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5086|M.smegmatis_MC2_155 -------------------------------------------------- TH_2434|M.thermoresistible__bu -------------------------------------------------- MAB_1342|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01346|M.leprae_Br4923 DPWVIDFGSPDKVEGGMRRNLADHIVALSEAVDTVKEVTGNDVHLVGYSQ Mb1238|M.bovis_AF2122/97 -------------------------------------------------- Rv1206|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4232|M.marinum_M -------------------------------------------------- MUL_0957|M.ulcerans_Agy99 -------------------------------------------------- MAV_1351|M.avium_104 -------------------------------------------------- Mvan_4510|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2185|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5086|M.smegmatis_MC2_155 -------------------------------------------------- TH_2434|M.thermoresistible__bu -------------------------------------------------- MAB_1342|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01346|M.leprae_Br4923 GGMFCYQAAAYRRSENIASIVAFGSPVDTLAALPMGIPPNFGVVLANFMA Mb1238|M.bovis_AF2122/97 -------------------------------------------------- Rv1206|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4232|M.marinum_M -------------------------------------------------- MUL_0957|M.ulcerans_Agy99 -------------------------------------------------- MAV_1351|M.avium_104 -------------------------------------------------- Mvan_4510|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2185|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5086|M.smegmatis_MC2_155 -------------------------------------------------- TH_2434|M.thermoresistible__bu -------------------------------------------------- MAB_1342|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01346|M.leprae_Br4923 DHVFNRLDIPSWLARAGFQMLDPLKTVKARVDFVRQLHNREALLSREQQR Mb1238|M.bovis_AF2122/97 -------------------------------------------------- Rv1206|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4232|M.marinum_M -------------------------------------------------- MUL_0957|M.ulcerans_Agy99 -------------------------------------------------- MAV_1351|M.avium_104 -------------------------------------------------- Mvan_4510|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2185|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5086|M.smegmatis_MC2_155 -------------------------------------------------- TH_2434|M.thermoresistible__bu -------------------------------------------------- MAB_1342|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01346|M.leprae_Br4923 RFLESEGWIAWSGPAISELLKQFIAHNRMMTGGFAVNGQMVTLTDITCPV Mb1238|M.bovis_AF2122/97 -------------------------------------------------- Rv1206|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4232|M.marinum_M -------------------------------------------------- MUL_0957|M.ulcerans_Agy99 -------------------------------------------------- MAV_1351|M.avium_104 -------------------------------------------------- Mvan_4510|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2185|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5086|M.smegmatis_MC2_155 -------------------------------------------------- TH_2434|M.thermoresistible__bu -------------------------------------------------- MAB_1342|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01346|M.leprae_Br4923 LAFVGEVDDIGQPASVRGIRRAAPNAEVYESLIRTGHFGLVVGSRAAQQS Mb1238|M.bovis_AF2122/97 ----------------------MSD---YYGGAHTTVRLIDLATRMPRVL Rv1206|M.tuberculosis_H37Rv ----------------------MSD---YYGGAHTTVRLIDLATRMPRVL MMAR_4232|M.marinum_M ----------------------MSD---RQSHVRTRVKLTDVAARVPGLL MUL_0957|M.ulcerans_Agy99 ----------------------MSD---RQSHVRTRVKLTDVAARVPGLL MAV_1351|M.avium_104 ----------------------MSD---RDGGARTAVKLTDIAARVPTVL Mvan_4510|M.vanbaalenii_PYR-1 ----------------------MTN----RSGTRSSVGLLDIAKQVPGLL Mflv_2185|M.gilvum_PYR-GCK ----------------------MSN----KSGTRSSVGLLDIAKQVPGLV MSMEG_5086|M.smegmatis_MC2_155 ----------------------MTD----QKATRNSVGLLDLATRLPGFL TH_2434|M.thermoresistible__bu ----------------------MSNERHNRSATRERVGLLDIAGRLPRMA MAB_1342|M.abscessus_ATCC_1997 ----------------------MSASSTIPSNPRDRVRLTDVLAQLPGLA MLBr_01346|M.leprae_Br4923 WPTVAEWVCWLAANANKPANIHIMPDQPVEHTASGVAISSRLAHGLGEVS : . : : . Mb1238|M.bovis_AF2122/97 ADTPVIVRGAMTGLLAR-------------------------PNSKASIG Rv1206|M.tuberculosis_H37Rv ADTPVIVRGAMTGLLAR-------------------------PNSKASIG MMAR_4232|M.marinum_M IDAPSIMRGAVTGLLPR-------------------------PKSKASIG MUL_0957|M.ulcerans_Agy99 IDAPSIMRGAVTGLLPR-------------------------PKSKASIG MAV_1351|M.avium_104 ADLPVIARGTLTGLLAQ-------------------------PGSHKSIG Mvan_4510|M.vanbaalenii_PYR-1 KDAPTIVRGVVTGFGAR-------------------------PTAKTSIG Mflv_2185|M.gilvum_PYR-GCK KDTPTMLRGVVTGFGAR-------------------------PSAKTSIG MSMEG_5086|M.smegmatis_MC2_155 MDAPVILRGVATGFTAR-------------------------PSAKTSIG TH_2434|M.thermoresistible__bu LDVPVMLRGVIAGFGAR-------------------------PSAKTSIG MAB_1342|M.abscessus_ATCC_1997 LDLPIMARGILSGIKST-------------------------PKGRWSIG MLBr_01346|M.leprae_Br4923 ETALALARGVADAIVAANRSVHTLAVETVRTLPRLARLGQLNDHTRISLG : ** .: . : *:* Mb1238|M.bovis_AF2122/97 TVFQDRAARYGDRVFLKFGDQQLTYRDANATANRYAAVLAARGVGPGDVV Rv1206|M.tuberculosis_H37Rv TVFQDRAARYGDRVFLKFGDQQLTYRDANATANRYAAVLAARGVGPGDVV MMAR_4232|M.marinum_M TVFQDRAARFGDRVFLKFGDQQMTYGEANATANRYAAVLAARGVGPGDVV MUL_0957|M.ulcerans_Agy99 TVFQDRAARFGDRVFLKFGDQQMTYGEANATANRYAAVLAARGVGPGDVV MAV_1351|M.avium_104 TVFQDRAARYGDRVFLRFGDQQLTYRDANAAANRYAAVLAARGVGHGDVV Mvan_4510|M.vanbaalenii_PYR-1 KVFQDRAAQYPNNVFLKFEDREITYREANDTVNRYAAVLAAKGVGHGDVV Mflv_2185|M.gilvum_PYR-GCK KVFQDRAAQYSNNVFLKFEDREITYGEANEIVNRYAAVLAAKGVGHGDVV MSMEG_5086|M.smegmatis_MC2_155 KVFQDRAAQYADRVFIKFGDERLTYKTANETVNRYAAVLAARGVGHGDVV TH_2434|M.thermoresistible__bu KVFQERAARYADKVFLKFEDQQLTYRQANETVNRYAAALAARGVGQGDVV MAB_1342|M.abscessus_ATCC_1997 GVFAERAAKHADRVFLRFEGQDITYAQANATANRYAATLASQGVGRGDVV MLBr_01346|M.leprae_Br4923 RIIGEQAHDAPRGEFLLFDGRVHTYEAVDRRVNNVVRGLIAVGVRQGDRV :: ::* *: * .. ** .: .*. . * : ** ** * Mb1238|M.bovis_AF2122/97 GIMLRNSPSTVLAMLATVKCGAIAGMLNYHQRGEVLAHSLGLLDAKVLIA Rv1206|M.tuberculosis_H37Rv GIMLRNSPSTVLAMLATVKCGAIAGMLNYHQRGEVLAHSLGLLDAKVLIA MMAR_4232|M.marinum_M GIMLRNSPNTVVAMLAVVKCGAIAGMLNYHQRGEVLAHSLGLLDAKVLVA MUL_0957|M.ulcerans_Agy99 GIMLRNSPNTVVAMLAVVKCGAIAGMLNYHQRGEVLAHSLGLLDAKVLVA MAV_1351|M.avium_104 AIMLRNSPNTVLAMLAAVKCGAVAGMLNYHQRGEVLAHSLGLLDAKVLIA Mvan_4510|M.vanbaalenii_PYR-1 GIMMRNSPEPILLMLAAVKCGAISGMLNYHQRDEVLKHSLGLLSAAVVVA Mflv_2185|M.gilvum_PYR-GCK GIMMRNSPEPILLMLAAVKCGAISGMLNYHQRDEVLKHSVGLLSASVMVA MSMEG_5086|M.smegmatis_MC2_155 GVMLRNSPDAVLLMLAIVKCGAIAGMLNYHQRGDVLKHSIGLLSATAVVA TH_2434|M.thermoresistible__bu GVMLKNEPRTVLLMLATVKLGAIAGMLNHHQKGDVLAHSIGLLDAKIVVS MAB_1342|M.abscessus_ATCC_1997 GIMLRNSPETVLLMLATVKLGAIAGMLNYNQRGHVLAHSIGLLDSKLLIT MLBr_01346|M.leprae_Br4923 GVLMETRPSALVAIAALSRLGAVAVMMRP---DADLAASVRIGGATKILT .:::.. * .:: : * : **:: *:. . * *: : .: ::: Mb1238|M.bovis_AF2122/97 ESDLVSAVAECGASRG-----------------RVAGDVLTVEDVERFAT Rv1206|M.tuberculosis_H37Rv ESDLVSAVAECGASRG-----------------RVAGDVLTVEDVERFAT MMAR_4232|M.marinum_M ESDLVSAVSESGG---------------------AAGEVVTIEDLERFAA MUL_0957|M.ulcerans_Agy99 ESDLVSAVSESGG---------------------AAGEVVTIEALERFAA MAV_1351|M.avium_104 ETDLVSAVAERGGS--------------------GSTETLTVEDLERFAV Mvan_4510|M.vanbaalenii_PYR-1 ETEFVEAITESGAD---------------------TDGLITLDELKQLAE Mflv_2185|M.gilvum_PYR-GCK ETDFVEPITESGAD---------------------TDGLMTLDELKKLAE MSMEG_5086|M.smegmatis_MC2_155 EPDFVDHIVESGAD---------------------TTGLMTVEELRRLAT TH_2434|M.thermoresistible__bu APDLVKQVEESDAD---------------------VADLLSADDLDRLSV MAB_1342|M.abscessus_ATCC_1997 EAEFEEAISESGVN---------------------VVSQLTIDELDRMSV MLBr_01346|M.leprae_Br4923 DPANLGVVLAYGRQLTGQVLVLGGGESRDLHLPEDALQQNQVIDMEKIDP . : . : :: Mb1238|M.bovis_AF2122/97 TAPATNPASASAVQAKDTAFYIFTSGTTGFPKASVMTHHRWLRALAVFGG Rv1206|M.tuberculosis_H37Rv TAPATNPASASAVQAKDTAFYIFTSGTTGFPKASVMTHHRWLRALAVFGG MMAR_4232|M.marinum_M TAPANNPASASAVQAQDTAFYIFTSGTTGFPKASVMTHHRWLRALAVFGG MUL_0957|M.ulcerans_Agy99 TAPANNPASASAVQAQDTAFYIFTSGTTGFPKASVMTHHRWLRALAVFGG MAV_1351|M.avium_104 SAPATNPASASAVQARDTAFYIFTSGTTGFPKASVMTHLRWLKALAAFGG Mvan_4510|M.vanbaalenii_PYR-1 TAPTTNPATTSAVLAKDKAFYIFTSGTTGMPKASVMTHYRWLRALAGFGG Mflv_2185|M.gilvum_PYR-GCK TAPTTNPATTSAVLAKDKAFYIFTSGTTGMPKASVMTHYRWLRALAGFGG MSMEG_5086|M.smegmatis_MC2_155 TAPTTNPASASAVLAKDKAFYIFTSGTTGLPKASVMTHYRWLRALAGFGG TH_2434|M.thermoresistible__bu DAPTTNPAITSSILAREKAFYIFTSGTTGLPKASVMTHYRWLRALAGFGA MAB_1342|M.abscessus_ATCC_1997 LAPTANPSATEAVMTKDRAFYIFTSGTTGLPKASVMTHYRWLRGMSGIGD MLBr_01346|M.leprae_Br4923 NAVDLPAWYRPNSGLARDLAFIACSTVGGELVAKQITNYRWAVSAFGTAS * . :* * . * *. :*: ** . . Mb1238|M.bovis_AF2122/97 MGLRLKGSDTLYSCLPLYHNNALTVAVSSVINSGATLALGKSFSASRFWD Rv1206|M.tuberculosis_H37Rv MGLRLKGSDTLYSCLPLYHNNALTVAVSSVINSGATLALGKSFSASRFWD MMAR_4232|M.marinum_M LGLRLKSSDTLYSCLPLYHNNALTVAVSSVINSGATLALGKSFSASRFWD MUL_0957|M.ulcerans_Agy99 LGLRLKSSDTLYSCLPLYHNNALTVAVSSVINSGATLALGKSFSASRFWD MAV_1351|M.avium_104 IGLRLKSSDTLYCCLPLYHNNALTVALSSVINSGATLALGKSFSASKFWD Mvan_4510|M.vanbaalenii_PYR-1 LGLRLNSSDTLYCCLPLYHNNALTVALSSVINSGATLALGKSFSASRFWD Mflv_2185|M.gilvum_PYR-GCK LGMRLNSNDTLYCCLPLYHNNALTVALSSVLNSGATLAIGKSFSASKFWD MSMEG_5086|M.smegmatis_MC2_155 LGLRLRSNDTLYCCLPLYHNNALTVSVGSVLNSGASLALGKSFSASRFWD TH_2434|M.thermoresistible__bu LGMRLRSSDTLYCCLPLYHNNALTVAVSSVLSAGATLALGKSFSASRFWD MAB_1342|M.abscessus_ATCC_1997 MALRLRPDDVLYSCLPLYHNNALTLAVSTTVNAGATLAIGRSFSVSRFWD MLBr_01346|M.leprae_Br4923 T-AALDRRDTVYCLTPLHHESALLVSLGGAVVGGARIALSRGLCSNRFVH * *.:*. **:*:.** :::. .: .** :*:.:.:. .:* . Mb1238|M.bovis_AF2122/97 EVIANRATAFVYIGEICRYLLNQPAKPTDRAHQVRVICGNGLRPEIWDEF Rv1206|M.tuberculosis_H37Rv EVIANRATAFVYIGEICRYLLNQPAKPTDRAHQVRVICGNGLRPEIWDEF MMAR_4232|M.marinum_M EVIASNATAFIYIGEVCRYLLNQPTKPTDRKHKVRVIAGNGLRPEIWGEF MUL_0957|M.ulcerans_Agy99 EVIASNATAFIYIGEVCRYLLNQPTKPTDRKHKVRVIAGNGLRPEIWGEF MAV_1351|M.avium_104 EVIANDATAFIYIGEVCRYLLNQPAKPTDRAHRVRLIAGNGLRPEIWDEF Mvan_4510|M.vanbaalenii_PYR-1 DVIRYDATAFVYIGEICTYLLNQPEKPTDRRHKVRVICGNGLRPAIWDAF Mflv_2185|M.gilvum_PYR-GCK DVIRYDATAFVYIGEICAYLLNQPEKPTDRKHKVRVICGNGLRPAIWDDF MSMEG_5086|M.smegmatis_MC2_155 EVIDYGATAFVYIGEICGYLLNQPPKPTDRAHKVRVIVGNGLRPAIWDEF TH_2434|M.thermoresistible__bu EVIRHDATAFVYIGEICGYLLNQPPKPTDRAHRVRVICGNGLRPAIWDDF MAB_1342|M.abscessus_ATCC_1997 EVIASRATAFIYIGELCRYLLNQPPKPTDRKHRVRVIVGNGLRPELWGEF MLBr_01346|M.leprae_Br4923 EVRQYGVTVVSYTWAMLRELVDDPAFVLHGNHPVRLFMGSGMPTGLWERV :* .*.. * : *:::* . * **:: *.*: . :* . Mb1238|M.bovis_AF2122/97 TTRFGVARVCEFYAASEGNSAFINIFNVPRTAGVSPMP----LAFVEYDL Rv1206|M.tuberculosis_H37Rv TTRFGVARVCEFYAASEGNSAFINIFNVPRTAGVSPMP----LAFVEYDL MMAR_4232|M.marinum_M TKRFDIDRVCEFYAASEGNSAFINIFNVPKSTGISPMP----LAYVAYDP MUL_0957|M.ulcerans_Agy99 TKRFDIDRVCEFYAASEGNSAFINIFNVPKSTGISPMP----LAYVAYDP MAV_1351|M.avium_104 TQRFGIARVCEFYASSEGNAAFINVFNVPRSTGIFPLP----LAYVEYDP Mvan_4510|M.vanbaalenii_PYR-1 TERFGIKRVCEFYAASEGNTAFVNVLNIDKTTGICPTP----IAFVEYDE Mflv_2185|M.gilvum_PYR-GCK TKRFGIDRVCEFYSASESNTAFVNFFNLDKTTGICPSP----IAFVEYDE MSMEG_5086|M.smegmatis_MC2_155 IERFGISRVCEFYAASEGNTAFVNVFNVSKSTGICPSP----VAFVEYDP TH_2434|M.thermoresistible__bu VERFGIERVCEFYSASEGNTAFVNAFNIDKTTGICPSP----VAFVEFDQ MAB_1342|M.abscessus_ATCC_1997 TARFGIKRVCEFYSASESNTAFVNALNIDRTVGICPMP----IAYVKYDV MLBr_01346|M.leprae_Br4923 VEAFAPAHVVEFFATVDGQAVLANVSGAKIGSKGRPLPGAGHVELGAYDA * :* **::: :.::.: * . * * : :* Mb1238|M.bovis_AF2122/97 DTGDPLRDASGRVRRVPDGEPGLLLSRVNRLQPFDGYTDPVASEKKLVRN Rv1206|M.tuberculosis_H37Rv DTGDPLRDASGRVRRVPDGEPGLLLSRVNRLQPFDGYTDPVASEKKLVRN MMAR_4232|M.marinum_M DTGAPLRDESGRVRRVPAGEPGLLLSRVNRLQPFDGYTDPAASEKKLVRD MUL_0957|M.ulcerans_Agy99 DTGAPLRDESGRVRRVPAGEPGLLLSRVNRLQPFDGYTDPAASEKKLVRD MAV_1351|M.avium_104 DTGAPLRGDDGRVRRVPPGQPGLLLSPVNRLQPFDGYTDPESSEKKLVRN Mvan_4510|M.vanbaalenii_PYR-1 NTGEPVRDEQGRVRRVKKGEPGLLLSKVSNYQPFDGYTDKKESEKKLVRD Mflv_2185|M.gilvum_PYR-GCK -SGDPLRDENGRVKKVKKGEPGLLLSKVSNFQPFDGYTDKKESEKKLVRD MSMEG_5086|M.smegmatis_MC2_155 DTGEPVRGADGKLRKVKSGEPGLLLSKVSSFQPFDGYTDSSATEKKLVRN TH_2434|M.thermoresistible__bu ETGEPLRGADGRVRKVKRGEPGLLLSKVSSFQPFDGYTDPQATEKKLVRN MAB_1342|M.abscessus_ATCC_1997 ESGEPVRNDKGFLTKVGPGESGLLLSKVTDLAPFDGYTDPTASEKKLVRD MLBr_01346|M.leprae_Br4923 EQDLILENDRGFVQVADVNQIGVLLAASR------GPIDPTASVK---RG . :.. * : . .: *:**: * * : * *. Mb1238|M.bovis_AF2122/97 AFRDGDCWFNTGDVMSPQGMGHAAFVDRLGDTFRWKGENVATTQVEAALA Rv1206|M.tuberculosis_H37Rv AFRDGDCWFNTGDVMSPQGMGHAAFVDRLGDTFRWKGENVATTQVEAALA MMAR_4232|M.marinum_M AFRKGDCWFNTGDVMSPQGMGHAAFVDRLGDTFRWKGENVATTQVEAALA MUL_0957|M.ulcerans_Agy99 AFRKGDCWFNTGDVMSPQGMGHAAFVDRLGDTFRWKGENVATTQVEAALA MAV_1351|M.avium_104 AFRDGDCWFNTGDVMSPQGLGHAAFVDRLGDTFRWKGENVATTQVEAALA Mvan_4510|M.vanbaalenii_PYR-1 AFKEGDVWFNTGDLMRAQGLGHAAFTDRLGDTFRWKGENVATTEVEAAVS Mflv_2185|M.gilvum_PYR-GCK AFKDGDVWFNTGDLMRSQGFGHAAFTDRLGDTFRWKGENVATTEVEAAVS MSMEG_5086|M.smegmatis_MC2_155 AFKDGDVWFNTGDLMRSQGFGHAAFADRLGDTFRWKGENVATTEVEAAVA TH_2434|M.thermoresistible__bu AFRDGDVWFNTGDLMRYQGFGHAAFVDRLGDTFRWKGENVATTEVEAAVS MAB_1342|M.abscessus_ATCC_1997 AFKKGDTWFNTGDLMRNLGWGHAAFGDRLGDTFRWKGENVATTEVEAAIE MLBr_01346|M.leprae_Br4923 VFAPADTWIATEYLLRRDYDGDYWLAGRRSSVVRTARGLVYTEPVTDALG .* .* *: * :: *. : .* ....* * * * *: Mb1238|M.bovis_AF2122/97 SDQTVEECTVYGVQIPRTGGRAGMAAITLRAGAEFDGQALARTVYGHLPG Rv1206|M.tuberculosis_H37Rv SDQTVEECTVYGVQIPRTGGRAGMAAITLRAGAEFDGQALARTVYGHLPG MMAR_4232|M.marinum_M SDPSVEECTVYGVEVPNTGGRAGMAAVKLRDGAEFDGQSLARAVYDQLPA MUL_0957|M.ulcerans_Agy99 SDPSVEECTVYGVEVPNTGGRAGMAAVKLRDGAEFDGQSLVRAVYDQLPA MAV_1351|M.avium_104 SDGSVEDCTVFGVEVPRTGGRAGMAAIKLRDGAEFDGRSLARTVYEQLPV Mvan_4510|M.vanbaalenii_PYR-1 THHQIEECTVFGVEVPDTGGRAGMVAIQLKEGHELDGQSLAKAVFEKLPS Mflv_2185|M.gilvum_PYR-GCK TDPQVEEATVFGVEVPDTGGRAGMVAIQLKDGKEFDGKALAKAAFDKLPG MSMEG_5086|M.smegmatis_MC2_155 SHHKIEECTVFGVEVPGAGGRAGMAAVQLKDGEEFDGKALADAFYGHLPA TH_2434|M.thermoresistible__bu ADPTVDEATVYGVEVEGTGGRAGMVALKLNEGCEFDGKSFAETLYKRLPV MAB_1342|M.abscessus_ATCC_1997 HNDAVEESTVFGVQVPGTDGRAGMAAIKLHDGVELDPKALSDTVYQNLPA MLBr_01346|M.leprae_Br4923 FITGVDLAATYSVAVDDR--ELAVSAVTLLPGAAITAADLTEAVAS-MPV :: .:.:.* : . .: *: * * : : : :* Mb1238|M.bovis_AF2122/97 YALPLFVRVVGSLAHTTTFKSRKVELRNQAYG----------ADIEDPLY Rv1206|M.tuberculosis_H37Rv YALPLFVRVVGSLAHTTTFKSRKVELRNQAYG----------ADIEDPLY MMAR_4232|M.marinum_M YALPLFVRLVQAMAHTTTFKSRKVELREQAYG----------ADVDDPLY MUL_0957|M.ulcerans_Agy99 YALPLFVRLVQAMAHTTTFKSRKVELREQAYG----------ADVDDPLY MAV_1351|M.avium_104 YALPLFVRVVDSIEQTTTFKSRKVELREQGYG----------PDVKDPLY Mvan_4510|M.vanbaalenii_PYR-1 YAVPLFVRVVQELAHTSTFKSQKGDLRKEGYGGSSGEGGDDDVKIDDPLY Mflv_2185|M.gilvum_PYR-GCK YAVPLFVRIVEELAHTSTFKSQKGDLRKEGYGGSSGEGDEDDVKVEDPIY MSMEG_5086|M.smegmatis_MC2_155 YAVPLFVRVVPELAHTSTFKSQKVDLRKQGYG----------PDVTDPVY TH_2434|M.thermoresistible__bu YAVPLFVRVVDEIEQTTTFKSRKVDLRNEGQG----------PHIEDPLY MAB_1342|M.abscessus_ATCC_1997 YALPLFIRIVDTLEHTTTFKSRKVELREQAYG----------ESVTDPLY MLBr_01346|M.leprae_Br4923 GLGPDIVHVVPELTLSATYRPIVGALRTAGIP-----------KTGRQVW * ::::* : ::*::. ** . :: Mb1238|M.bovis_AF2122/97 VLAGPDEGYVPYYAEYPEEVSLGRRPQG- Rv1206|M.tuberculosis_H37Rv VLAGPDEGYVPYYAEYPEEVSLGRRPQG- MMAR_4232|M.marinum_M VLAGRSEGYVPYYDAYPDEVAAGKRPQG- MUL_0957|M.ulcerans_Agy99 VLAGRSEGYVPYYDAYPDEVAAGKRPQG- MAV_1351|M.avium_104 VLAGRDEGYVPFYDEYPDEVAEGKRP--- Mvan_4510|M.vanbaalenii_PYR-1 VLSGREEGYVPFYDEYPHEVREGKKPK-- Mflv_2185|M.gilvum_PYR-GCK VLSGREEGYVEFYEEYLVEVKDGKKPT-- MSMEG_5086|M.smegmatis_MC2_155 VLAGRDEGYVPFYDEYPEEVTAGKRPKN- TH_2434|M.thermoresistible__bu VLAGREEGYVPFYEEYAAEVRDGKRPVN- MAB_1342|M.abscessus_ATCC_1997 VLAGRAEGYVPFYPEYPEELAGGQRPKG- MLBr_01346|M.leprae_Br4923 YFDSASNQFRRMTPGVRAELAGKHTHTHA : . : : *: :