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VDFSAITRPVGRLVATAQNGLEVLRYGGLETGAVPSPFQIIESVPMYRLRRYFPPDVRPGSKPVGPPVLM VHPMMMSADMWDVTRDEGAVGILHKAGIDPWVIDFGSPDKVEGGMQRNLADHVVALSDAIDTVKTVTGRD VHLAGYSQGGMFAYQTAAYRRSKDLASIVGFGSPVDTLAALPMNLPASVAPLAADFMADHVFSRIDIPGW LARTGFQMLDPVKTAQSRLDFLRQLHDREALLPREQQRRFLASEGWIAWSGPAISELLKQFIAHNRMMTG GFSIHGDLVTLSDIECPVLAVIGEVDDIGQPASVRGIKRAAPKADVYEFLIRAGHFGLVVGSKAATQTWP TVAEWVRWLDSGGAMPEGVTPMPLQPAEPTESGVTLASRVAHSTAAATEMAFSLARSAADALVAANKSAR TLAIETARTLPRLARLGQVNDHTRISLGRIMSEQARDLPHGEALLFDGRVHTYEAVDRRVNNVVRGLIGV GVRQGARVGVLMETRPSALVAIAALSRLGAVAVLMPPDADLAEAARLGAVTEIIADPSTLDTARKLDMRV LVLGGGESRDLHLSNGAAGDVIDMEKIDPDLVELPGWYRPNPGLARDLAFIGFSTISGELVARQITNFRW ALSAFGTASAANLSRNDTVYCLTPLHHQSGLLVSLGGAVVGGARVALSRELRPDRFVQEIRQYGVTVVSY TWAMLREVIDDPAFSLNGSHPIRLFIGSGMPAGLWKRVVEVFEPANVVEFFATTDGQAVLANVKGAKIGS KGRPLPGGGEIALAAYDPDDNLILEDDRGFVRRAETGEVGVLLAHPRGPVDPLASVKRGVFAPADTWVST EYLFRRDEDGDYWLVDNRGAAIHTARGMVFAATVNDAVGRLGAVDMAVTYGVEVEGQTLAVTALALCPGG SIPSADLSEALAALPVGNAPDIVHVVSDMTLTATFRPLAGPLQKQGIPKASRNAWYLDPDSNRYKRLTVA VRSELAGIRQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3301 | - | - | 100% (991) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_4510 | - | 2e-40 | 25.98% (535) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_4341 | - | 1e-15 | 24.11% (535) | acyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1710 | - | 0.0 | 73.71% (989) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_3517 | - | 0.0 | 90.21% (991) | acyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv1683 | - | 0.0 | 73.71% (989) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_01346 | - | 0.0 | 71.50% (993) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_2348 | - | 0.0 | 67.68% (987) | acyl-CoA synthetase |
| M. marinum M | MMAR_2478 | - | 0.0 | 72.85% (987) | long-chain acyl-CoA synthase |
| M. avium 104 | MAV_3089 | - | 0.0 | 73.37% (995) | acyl-CoA synthetase |
| M. smegmatis MC2 155 | MSMEG_3767 | - | 0.0 | 82.39% (988) | acyl-CoA synthetase |
| M. thermoresistible (build 8) | TH_2090 | - | 0.0 | 82.06% (992) | Possible long-chain acyl-CoA synthase |
| M. ulcerans Agy99 | MUL_1660 | - | 0.0 | 71.63% (994) | acyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3301|M.vanbaalenii_PYR-1 --MVDFSAITRPVGRLVATAQNGLEVLRYGGLETGAVPSPFQIIESVPMY
Mflv_3517|M.gilvum_PYR-GCK --MVDLSAITRPVGRLVATAQNGLEVLRYGGLETGAVPSPFQIIESVPMY
MSMEG_3767|M.smegmatis_MC2_155 ---MDFSAVTKPIERLLATAQNGLEVLRYGGLETGAVPSPFQIIQSVPMF
TH_2090|M.thermoresistible__bu --VVNLKAISKPVERLVATAQNGLEVLRYGGLQTDMAPSPFQIIQSVPMY
MMAR_2478|M.marinum_M -MDLNLSMVTRPVERLVATAQNGLEVLRLGGLETGSVPSPSQIVESVPMY
MUL_1660|M.ulcerans_Agy99 MVDLNLSMVTRPVERLVATAQNGLEVLRLGGLETGSVPSPSQIVESVPMY
Mb1710|M.bovis_AF2122/97 MVDLNFSMVTRPIERLVATAQNGLEVLRLGGLETGSVPSPSQIVESVPMY
Rv1683|M.tuberculosis_H37Rv MVDLNFSMVTRPIERLVATAQNGLEVLRLGGLETGSVPSPSQIVESVPMY
MLBr_01346|M.leprae_Br4923 -MDLNFSIVTRPVERLVATAQNGLEVLRLGGLETGSFPSPSQIVESVPMY
MAV_3089|M.avium_104 -MDLNLSMVTRPVGRLIATAQNGLEVLRLGGLETGTVASPSQIVESVPMY
MAB_2348|M.abscessus_ATCC_1997 -MAFNISSLTKPVARLAATAQNGLEVLRLGGLETGSTASSHQIVESVPMY
.::. :::*: ** *********** ***:*. .*. **::****:
Mvan_3301|M.vanbaalenii_PYR-1 RLRRYFPPDVRPGSKPVGPPVLMVHPMMMSADMWDVTRDEGAVGILHKAG
Mflv_3517|M.gilvum_PYR-GCK RLRRYFPPDSRPGAKTPGAPVLMVHPMMMSADMWDVTRDDGAVGILHRAG
MSMEG_3767|M.smegmatis_MC2_155 KLRRYFPPDARPGAQIVGPPVLMVHPMMMSADMWDVTRESGAVGILHRAG
TH_2090|M.thermoresistible__bu RLRRYFPPDTRPEAPPPGPPVLMVHPMMMSADMWDVTRESGAVGILHRSG
MMAR_2478|M.marinum_M KLRRYFPPDNRPGQPPVGPPVLMVHPMMMSADMWDVTREEGAVGILHARG
MUL_1660|M.ulcerans_Agy99 KLRRYFPPDNRPGQPPVGPPVLMVHPMMMSADMWDVTREEGAVGILHARG
Mb1710|M.bovis_AF2122/97 KLRRYFPPDNRPGQPPVGPPVLMVHPMMMSADMWDVTREDGAVGILHASG
Rv1683|M.tuberculosis_H37Rv KLRRYFPPDNRPGQPPVGPPVLMVHPMMMSADMWDVTREDGAVGILHASG
MLBr_01346|M.leprae_Br4923 KLRRYFPPGNRPGQPLLGAPVLMVHPMMMSADMWDVTREEGAVGILHVRG
MAV_3089|M.avium_104 KLRRYFPPDSRPGQPPVGPPVLMVHPMMMSADMWDVTRDEGAVGILHAHG
MAB_2348|M.abscessus_ATCC_1997 RLRRYFAPG--AGTEDAGPVVLMVHPMMMAADMWDVTQDGGAVGILHRAG
:*****.*. . *. *********:*******:: ******* *
Mvan_3301|M.vanbaalenii_PYR-1 IDPWVIDFGSPDKVEGGMQRNLADHVVALSDAIDTVKTVTGRDVHLAGYS
Mflv_3517|M.gilvum_PYR-GCK LDPWVIDFGSPDKIEGGMQRNLADHVVALSEAIDTVKTVTGRDVHLAGYS
MSMEG_3767|M.smegmatis_MC2_155 IDPWVIDFGEPDKVEGGMERTLADHVVALSEAIDTVREVTGRDVHLAGYS
TH_2090|M.thermoresistible__bu IDPWVIDFGSPDKIEGGMQRNLADHVVALSEAIDVVKQVTGRDVHLAGYS
MMAR_2478|M.marinum_M LDPWVIDFGSPDKVEGGMRRNLADHIVALSEVIDTVKDTTGSDVHIVGYS
MUL_1660|M.ulcerans_Agy99 LDPWVIDFGSPDKVEGGMRRNLADHIVALSVVIDTVKDTTGSDVHIVGYS
Mb1710|M.bovis_AF2122/97 LDPWVIDFGSPDEVEGGMRRNLADHIVALSEAVDTVKDATGHDVHFVGYS
Rv1683|M.tuberculosis_H37Rv LDPWVIDFGSPDEVEGGMRRNLADHIVALSEAVDTVKDATGHDVHFVGYS
MLBr_01346|M.leprae_Br4923 LDPWVIDFGSPDKVEGGMRRNLADHIVALSEAVDTVKEVTGNDVHLVGYS
MAV_3089|M.avium_104 LDPWVIDFGEPDKVEGGMRRTLTDHIVALSQAIDTVKDVTGADIHLVGYS
MAB_2348|M.abscessus_ATCC_1997 IDPWVIDFGSPDRMAGGMERTLSDHVVAVSDAIETVHRITGRQIHLAGYS
:********.**.: ***.*.*:**:**:* .::.*: ** ::*:.***
Mvan_3301|M.vanbaalenii_PYR-1 QGGMFAYQTAAYRRSKDLASIVGFGSPVDTLAALPMNLPASVAPLAADFM
Mflv_3517|M.gilvum_PYR-GCK QGGMFAYQTAAYRRSKDLASIVAFGAPVDTLAALPMNLPPSLAPLAADFM
MSMEG_3767|M.smegmatis_MC2_155 QGGMFAYQAAAYRRSKDLASIIAFGSPVDTLAALPMNLPSSIAPAAADFM
TH_2090|M.thermoresistible__bu QGGMFCYQAAAYRRSKDLASIIAFGAPVDTLAALPLNLPAGPAAAAADFM
MMAR_2478|M.marinum_M QGGMFCYQAAAYRRSKNIASIVAFGSPVDTLAALPMGIPANYGAAIADFM
MUL_1660|M.ulcerans_Agy99 QGGMFCYQAAAYRRSKNIASIVAFGSPVDTLAALPMGIPANYGAAIADFM
Mb1710|M.bovis_AF2122/97 QGGMFCYQAAAYRRSKDIASVVAFGSPVDTLAALPMGIPANMGAAVADFM
Rv1683|M.tuberculosis_H37Rv QGGMFCYQAAAYRRSKDIASVVAFGSPVDTLAALPMGIPANMGAAVADFM
MLBr_01346|M.leprae_Br4923 QGGMFCYQAAAYRRSENIASIVAFGSPVDTLAALPMGIPPNFGVVLANFM
MAV_3089|M.avium_104 QGGMWCYQVAAYRRSKSLASIVTFGSPVDTLAALPMGIPANFAAPAANFM
MAB_2348|M.abscessus_ATCC_1997 QGGMFCYQTAALRKSRTIASIITFGSPVDANAAMPMGMPAGLSADIAEFM
****:.**.** *:*. :**:: **:***: **:*:.:*.. . *:**
Mvan_3301|M.vanbaalenii_PYR-1 ADHVFSRIDIPGWLARTGFQMLDPVKTAQSRLDFLRQLHDREALLPREQQ
Mflv_3517|M.gilvum_PYR-GCK ADHVFSRIDIPGWLARTGFQMLDPIKTAQSRIDFLRQLHDREALLPREQQ
MSMEG_3767|M.smegmatis_MC2_155 ADHVFSRIDIPGWLARTGFQMLDPIKTAQSRIDFLRQLHDREALLPREQQ
TH_2090|M.thermoresistible__bu ADHVFSRIDIPGWLARTGFQMLDPVKTAQARLEFLRQLHDREALLPREQQ
MMAR_2478|M.marinum_M ADHVFNRLDIPSWMARAGFQMMDPLKTAKARVDFVRQLHDREALLPREQQ
MUL_1660|M.ulcerans_Agy99 ADHVFNRLDIPSWMARAGFQMMDPLKTAKARVDFVRQLHDREALLPREQQ
Mb1710|M.bovis_AF2122/97 ADHVFNRLDIPSWMARMGFQMMDPLKTAKARVDFVRQLHDREALLPREQQ
Rv1683|M.tuberculosis_H37Rv ADHVFNRLDIPSWMARMGFQMMDPLKTAKARVDFVRQLHDREALLPREQQ
MLBr_01346|M.leprae_Br4923 ADHVFNRLDIPSWLARAGFQMLDPLKTVKARVDFVRQLHNREALLSREQQ
MAV_3089|M.avium_104 ADHVFSRLAIPSWMARTGFQMLDPLKTAKARVDFLRQLHDREALLPREQQ
MAB_2348|M.abscessus_ATCC_1997 ADHVFSRFSIPAWSARIGFQMLDPVKTIKGRLDFLRQLHDRDALLPREQQ
*****.*: **.* ** ****:**:** :.*::*:****:*:***.****
Mvan_3301|M.vanbaalenii_PYR-1 RRFLASEGWIAWSGPAISELLKQFIAHNRMMTGGFSIHGDLVTLSDIECP
Mflv_3517|M.gilvum_PYR-GCK RRFLASDGWIAWSGPAISELLKQFIAHNRMMTGGFAIRGDLVTLSDIDVP
MSMEG_3767|M.smegmatis_MC2_155 RRFLASEGWIAWSGPAISELLKQFIAHNRMITGGFSIHGDLVTLSDINCP
TH_2090|M.thermoresistible__bu RRFLASEGWIAWSGPAISELLKQFIAHNRMMTGGFSINGELVTLSDIKCP
MMAR_2478|M.marinum_M RRFLEREGWIAWSGPAISELLKQFIAHNRMMTGGFAINGQMVTLTDITCP
MUL_1660|M.ulcerans_Agy99 RRFLEREGWIAWSGPAISELLKQFIAHNRMMTGGFAINGQMVTLTDITCP
Mb1710|M.bovis_AF2122/97 RRFLESEGWIAWSGPAISELLKQFIAHNRMMTGGFAISGQMVTLTDITCP
Rv1683|M.tuberculosis_H37Rv RRFLESEGWIAWSGPAISELLKQFIAHNRMMTGGFAISGQMVTLTDITCP
MLBr_01346|M.leprae_Br4923 RRFLESEGWIAWSGPAISELLKQFIAHNRMMTGGFAVNGQMVTLTDITCP
MAV_3089|M.avium_104 RRFLEREGWIAWSGPAISELLKQFIAHNRMMTGGFAVNGQMVTLTDITCP
MAB_2348|M.abscessus_ATCC_1997 RKFLANEGWIAWSGPAIAELLRQFVVHNRMTTGGFTVNDRVVTLSDITCP
*:** :**********:***:**:.**** ****:: . :***:** *
Mvan_3301|M.vanbaalenii_PYR-1 VLAVIGEVDDIGQPASVRGIKRAAPKADVYEFLIRAGHFGLVVGSKAATQ
Mflv_3517|M.gilvum_PYR-GCK VLAVIGEVDDIGQPASVRGIKRAAPKADVYEFLIRAGHFGLVVGSKASTE
MSMEG_3767|M.smegmatis_MC2_155 ILAVVGEVDDIGQPASVRGIKRAAPQADVYEYLIRAGHFGLVVGSKASEQ
TH_2090|M.thermoresistible__bu VLAVVGEVDDIGQPASVRGIKRAAPDADVYEFTIRAGHFGLVVGSKASSQ
MMAR_2478|M.marinum_M VLAFVGEVDDIGQPASVRGIRRAAPNTDVYECLIRTGHFGLVVGSRAAQQ
MUL_1660|M.ulcerans_Agy99 VLAFVGEVDDIGQPASVRGIRRAAPNTDVYECLIRTGHFGLVVGSRAAQQ
Mb1710|M.bovis_AF2122/97 ILAFVGEVDDIGQPASVRGIRRAAPNSEVYECLIRAGHFGLVVGSRAAQQ
Rv1683|M.tuberculosis_H37Rv ILAFVGEVDDIGQPASVRGIRRAAPNSEVYECLIRAGHFGLVVGSRAAQQ
MLBr_01346|M.leprae_Br4923 VLAFVGEVDDIGQPASVRGIRRAAPNAEVYESLIRTGHFGLVVGSRAAQQ
MAV_3089|M.avium_104 VLAFVGEVDDIGQPASVRGIRRAAPDAEVYECTIRTGHFGLVVGSKAAQH
MAB_2348|M.abscessus_ATCC_1997 VLAVVGEVDDIGQPASVRGILRAAPKADVYEYLIRAGHFGLVVGSTAVAQ
:**.:*************** ****.::*** **:********* * .
Mvan_3301|M.vanbaalenii_PYR-1 TWPTVAEWVRWLDSGGAMPEGVTPMPLQPAEPTE-SGVTLASRVAHSTAA
Mflv_3517|M.gilvum_PYR-GCK TWPTVAAWVRWLDGGGSMPDGVSPMALQPAEPTE-SGVTLASRLAHSATA
MSMEG_3767|M.smegmatis_MC2_155 TWPTVAQWVKSLEIGEPMPEGVVPMATQPPDQHE-GGVSISSRITHGANA
TH_2090|M.thermoresistible__bu TWPTVAKWVKWIEGGTEMPEQVAPMAPQAADPDE-TGVTLASRVAHGTAA
MMAR_2478|M.marinum_M SWPTVADWVNWLSRDADKPANISLMVEQPAEHTD-SGVAFSSRVAHGLGE
MUL_1660|M.ulcerans_Agy99 SWPTVADWVNWLSRDADKPANISLMVEQPAEHTD-SGVAFSSRVAHGLGE
Mb1710|M.bovis_AF2122/97 SWPTVADWVRWISGDGTKPENIHLMADQPAEHTD-SGVAFSSRVAHGIGE
Rv1683|M.tuberculosis_H37Rv SWPTVADWVRWISGDGTKPENIHLMADQPAEHTD-SGVAFSSRVAHGIGE
MLBr_01346|M.leprae_Br4923 SWPTVAEWVCWLAANANKPANIHIMPDQPVEHTA-SGVAISSRLAHGLGE
MAV_3089|M.avium_104 SWPTVAAWVKWLSTGGDKPTGIDPMADQPAEHTD-SGVALSSRIAHELGE
MAB_2348|M.abscessus_ATCC_1997 TWPTVSQWVQWREGEAAKPPSVDLMYEHEAGQLDRGGVPLASRVAHGLST
:****: ** * : * : **.::**::*
Mvan_3301|M.vanbaalenii_PYR-1 ATEMAFSLARSAADALVAAN-------KSARTLAIETARTLPRLARLGQV
Mflv_3517|M.gilvum_PYR-GCK ATEMAFSLARSAADALVTAN-------KSARTLAVETARTLPRLTRLGQV
MSMEG_3767|M.smegmatis_MC2_155 ATEVAFEVARNAADALVAAN-------KSARTLVVETARTLPRLARLGQV
TH_2090|M.thermoresistible__bu AGEMVFTLARTAADAVVAAN-------RSARTLAVETARTLPRLTRLGQI
MMAR_2478|M.marinum_M VSEAALAVARGAAEAVFAAN-------RSVRTLAVETVRTLPRLARLGQL
MUL_1660|M.ulcerans_Agy99 VSEAALAVARGAAEAVFAANRSVFAANRSVRTLAVETVRTLPRLARLGQL
Mb1710|M.bovis_AF2122/97 VSEAALALARGAADAVVAAN-------RSVRTLAVETVRTLPRLARLGQL
Rv1683|M.tuberculosis_H37Rv VSEAALALARGAADAVVAAN-------RSVRTLAVETVRTLPRLARLGQL
MLBr_01346|M.leprae_Br4923 VSETALALARGVADAIVAAN-------RSVHTLAVETVRTLPRLARLGQL
MAV_3089|M.avium_104 ASEAAIGLVRGAANAVVTAN-------KSVRTLAVETARTLPRLVRLGQI
MAB_2348|M.abscessus_ATCC_1997 TTEVAITAARTAGAAAAAAN-------KSVKSIAVEAVRTLPRLTRLGQI
. * .: .* .. * :** :*.:::.:*:.******.****:
Mvan_3301|M.vanbaalenii_PYR-1 NDHTRISLGRIMSEQARDLPHGEALLFDGRVHTYEAVDRRVNNVVRGLIG
Mflv_3517|M.gilvum_PYR-GCK NDHTRISLGRIMSEQARDMPHGEALLFDGRVHTVEAVDRRVNNVVRGLIE
MSMEG_3767|M.smegmatis_MC2_155 NDHTRISLGRIMSEQARNAPSGEALLFDGRVHTYEAVDRRINNVVRGLID
TH_2090|M.thermoresistible__bu TDHTRISLGRIMSEQARNAPRGECLLFDGRVHTYEAVDRRINNVVRGLID
MMAR_2478|M.marinum_M NDHTRISLGRIIDEQARDAPQGEFLLFDDRVHTYEAVNRRINNVVRGLIE
MUL_1660|M.ulcerans_Agy99 NDHTRISLGRIIDEQARNAPQGEFLLFDDRVHTYEAVNRRINNVVRGLIE
Mb1710|M.bovis_AF2122/97 NDHTRISLGRIIDEQAHDAPKGEFLLFDGRVHTYEAVNRRINNVVRGLIA
Rv1683|M.tuberculosis_H37Rv NDHTRISLGRIIDEQAHDAPKGEFLLFDGRVHTYEAVNRRINNVVRGLIA
MLBr_01346|M.leprae_Br4923 NDHTRISLGRIIGEQAHDAPRGEFLLFDGRVHTYEAVDRRVNNVVRGLIA
MAV_3089|M.avium_104 NDHTRISLGRIIEEQAHDAPQGEFLLFDGRVHTYEAVNRRINNVVRGLIE
MAB_2348|M.abscessus_ATCC_1997 HDHTRISMGRLMTEQARRTPHGECFLFDGRVHTYEAVDRRINNVVKGLIE
******:**:: ***: * ** :***.**** ***:**:****:***
Mvan_3301|M.vanbaalenii_PYR-1 VGVRQGARVGVLMETRPSALVAIAALSRLGAVAVLMPPDADLAEAARLGA
Mflv_3517|M.gilvum_PYR-GCK VGVRQGARVGLLMETRPSALVAIAALSRLGAVAVLMPPDSDLAEAARLGG
MSMEG_3767|M.smegmatis_MC2_155 VGVRQGAHVGVLMETRPSALVAIAALSRLGAVAVLIPPDVDLAEAIRLGG
TH_2090|M.thermoresistible__bu VGVRQGTRVGVLMETRPSALVAIAALSRLGAVAVLIPPDADLAEAARLGA
MMAR_2478|M.marinum_M VGVRQGDRVGVLMETRPSALVAIAALSRLGAVAVLMRQDVDLAAQVRLGG
MUL_1660|M.ulcerans_Agy99 VGVRQGDRVGVLMETRPSALVAIAALSRLGAVAVLMRQDVDLAAQVRLGG
Mb1710|M.bovis_AF2122/97 VGVRQGDRVGVLMETRPSALVAIAALSRLGAVAVVMRPDTDLSASVRLGR
Rv1683|M.tuberculosis_H37Rv VGVRQGDRVGVLMETRPSALVAIAALSRLGAVAVVMRPDTDLSASVRLGR
MLBr_01346|M.leprae_Br4923 VGVRQGDRVGVLMETRPSALVAIAALSRLGAVAVMMRPDADLAASVRIGG
MAV_3089|M.avium_104 VGVRQGDRVGVLMETRPSALVAIAALSRLGAIAVVMRPDADLAASVRLGG
MAB_2348|M.abscessus_ATCC_1997 VGVRQGVRVGILMETRPSALVAIAALSRLGAVAVLLPPDADLEVAVKLGE
****** :**:********************:**:: * ** ::*
Mvan_3301|M.vanbaalenii_PYR-1 VTEIIADPSTL----DTARKLDMRVLVLGGGESRDLHLSNGA--AGDVID
Mflv_3517|M.gilvum_PYR-GCK VTEIIADPSNL----AAAGALDMRVLVLGGGESRDLDVPD----SGRIID
MSMEG_3767|M.smegmatis_MC2_155 VSEIIADPTHL----EAALALDVRVLVLGGGEDRNLNLPDG----ADVTD
TH_2090|M.thermoresistible__bu VTEIIADPGHL----DAARALGQRVLVLGGGENRDLNLTLSED-VADIVD
MMAR_2478|M.marinum_M ATEILADPTNL----AAARQLPGQILVLGGGEARDLDLPEDAD----VID
MUL_1660|M.ulcerans_Agy99 ATEILADPTNL----AAARQLPGQILVLGGGEARDLDLPEDAD----VID
Mb1710|M.bovis_AF2122/97 VTEILTDPTNL----DAARQLPGQVLVLGGGESRDLDLPADALEQGQVID
Rv1683|M.tuberculosis_H37Rv VTEILTDPTNL----DAARQLPGQVLVLGGGESRDLDLPADALEQGQVID
MLBr_01346|M.leprae_Br4923 ATKILTDPANLGVVLAYGRQLTGQVLVLGGGESRDLHLPEDALQQNQVID
MAV_3089|M.avium_104 ATEILTDPTNLESVLASDRQLLRQVLVLGGGEARDLHLPEDSAEQPYVID
MAB_2348|M.abscessus_ATCC_1997 ISELLTDPPNL----PAAQDLPVHVLVLGGGESRDLSIPDDGS----TID
:::::** * * ::******* *:* :. *
Mvan_3301|M.vanbaalenii_PYR-1 MEKIDPDLVELPGWYRPNPGLARDLAFIGFSTISGELVARQITNFRWALS
Mflv_3517|M.gilvum_PYR-GCK MEKIDPDVVELPGWYRPNPGLARDLAFIGFSTVSGELVARQITNYRWALS
MSMEG_3767|M.smegmatis_MC2_155 MEQIDPDSVELPGWYRPNPGLARDLAFVGFSTIGGELIPRQITNYRWALS
TH_2090|M.thermoresistible__bu MEQIDPDEVELPGWYRPNPGLACDLAFIAFSRTDGELVARQITNFRWAVS
MMAR_2478|M.marinum_M MEQIDPDAVELPAWYRQNPGLARDLAFIAFSGIGGELVAKQITNYRWAVS
MUL_1660|M.ulcerans_Agy99 MEQIDPDAVELPAWYQQNPGLARDLAFIAFSGIGGVLVAKQITNYRWAVS
Mb1710|M.bovis_AF2122/97 MEKIDPDAVELPAWYRPNPGLARDLAFIAFSSADGDLVAKQITNYRWAVS
Rv1683|M.tuberculosis_H37Rv MEKIDPDAVELPAWYRPNPGLARDLAFIAFSSADGDLVAKQITNYRWAVS
MLBr_01346|M.leprae_Br4923 MEKIDPNAVDLPAWYRPNSGLARDLAFIACSTVGGELVAKQITNYRWAVS
MAV_3089|M.avium_104 MEKIDPDAVELPGWYRPNPGLARDLAFIAFSAAGGELVAKQITNYRWAVS
MAB_2348|M.abscessus_ATCC_1997 MEKIDPDAVELPGWYRPDPGQARDLAFVMFSGAGSKLLPKQITNHRWALS
**:***: *:**.**: :.* * ****: * .. *:.:****.***:*
Mvan_3301|M.vanbaalenii_PYR-1 AFGTASAANLSRNDTVYCLTPLHHQSGLLVSLGGAVVGGARVALSRELRP
Mflv_3517|M.gilvum_PYR-GCK AFGTASAANLSRSDTVYCLTPLHHQSGLLVSLGGAVVGGSRIALSRELRP
MSMEG_3767|M.smegmatis_MC2_155 AFGTASAANLGRADTVYCLTPLHHQSGLLVSLGGAVVGGSRIALSRGLQP
TH_2090|M.thermoresistible__bu AFGTASAANLGRGDTVYCLTPLHHQSGLLVALGGAVVGGSRIALSRGLRP
MMAR_2478|M.marinum_M AFGTASTASLDRKDTVYALTPLHHESALLVSLGGAVVGGARIALSRGLRP
MUL_1660|M.ulcerans_Agy99 AFGTASTASLDRKDTVYALTPLHHESALLVSLGGAVVGGARIALSRGLRP
Mb1710|M.bovis_AF2122/97 AFGTASTAALGRRDTVYCLTPLHHESALLVSLGGAVVGGTRIALSRGLRP
Rv1683|M.tuberculosis_H37Rv AFGTASTAALGRRDTVYCLTPLHHESALLVSLGGAVVGGTRIALSRGLRP
MLBr_01346|M.leprae_Br4923 AFGTASTAALDRRDTVYCLTPLHHESALLVSLGGAVVGGARIALSRGLCS
MAV_3089|M.avium_104 AFGTASTAALDRRDTVYCLTPLHHESALLVSLGGAVVGGTRIALSRGLDR
MAB_2348|M.abscessus_ATCC_1997 AFGTASAAALSSNDTVYCLTPMHHQSGLLVSIGGSVAGGARIALSRGLDP
******:* *. ****.***:**:*.***::**:*.**:*:**** *
Mvan_3301|M.vanbaalenii_PYR-1 DRFVQEIRQYGVTVVSYTWAMLREVIDDPAFSLNGSHPIRLFIGSGMPAG
Mflv_3517|M.gilvum_PYR-GCK DRFVQEIRQYGVTVVSYTWAMLREVIDDPGFSLRGSHPVRLFIGAGMPAG
MSMEG_3767|M.smegmatis_MC2_155 NRFLQEIRQYGVTVVSYTWAMLREVIDDPSFTLKGSHSVRVFIGSGMPAG
TH_2090|M.thermoresistible__bu DRFVHELRQYGVTVVSYTWAMLGEVIDDPGFSLSGGHPVRLFIGSGMPTG
MMAR_2478|M.marinum_M DRFLNEVRRYGVTVVSYTWAMLRDVVDNPEFALHGNHPVRLFIGSGMPTG
MUL_1660|M.ulcerans_Agy99 DRFLNEVRRYGVTVVSYTWAMLRDVVDNPEFAFHGNHPVRLFIGSGMPTG
Mb1710|M.bovis_AF2122/97 DRFVAEVRQYGVTVVSYTWAMLRDVVDDPAFVLHGNHPVRLFIGSGMPTG
Rv1683|M.tuberculosis_H37Rv DRFVAEVRQYGVTVVSYTWAMLRDVVDDPAFVLHGNHPVRLFIGSGMPTG
MLBr_01346|M.leprae_Br4923 NRFVHEVRQYGVTVVSYTWAMLRELVDDPAFVLHGNHPVRLFMGSGMPTG
MAV_3089|M.avium_104 DRFVQEVRQYGVTVVSYTWAMLREIVDDPAFVLHGNHPVRLFIGSGMPTG
MAB_2348|M.abscessus_ATCC_1997 DRFVQEIHQYGVSVVSYTWAMMHEVIDDPALALGAHHPVRLFIGSGMPAG
:**: *:::***:********: :::*:* : : . *.:*:*:*:***:*
Mvan_3301|M.vanbaalenii_PYR-1 LWKRVVEVFEPANVVEFFATTDGQAVLANVKGAKIGSKGRPLPGGGEIAL
Mflv_3517|M.gilvum_PYR-GCK LWKRVVDVFAPANVVEFFATTDGQAVLANVKGAKIGSKGRPLPGGGEIAL
MSMEG_3767|M.smegmatis_MC2_155 LWKRVTEVFEPAQVVEFFATTDGQAVLANVSGHKVGSKGRPLPGGGQIEL
TH_2090|M.thermoresistible__bu LWKRVVDIFEPAQVVEFFATTDGHAVLANVSGAKIGSKGRPLPGVRQLEL
MMAR_2478|M.marinum_M LWERVVETFAPAHVVEFFATTDGQAVLANVSGAKIGSKGRPLPGAGRVEL
MUL_1660|M.ulcerans_Agy99 LWERVVETFAPAHVVEFFATTDGQALLANVSGAKIDSKGRPLPGAGRVEL
Mb1710|M.bovis_AF2122/97 LWERVVEAFAPAHVVEFFATTDGQAVLANVAGAKIGSKGRPLPGAGRVEL
Rv1683|M.tuberculosis_H37Rv LWERVVEAFAPAHVVEFFATTDGQAVLANVAGAKIGSKGRPLPGAGRVEL
MLBr_01346|M.leprae_Br4923 LWERVVEAFAPAHVVEFFATVDGQAVLANVSGAKIGSKGRPLPGAGHVEL
MAV_3089|M.avium_104 LWGRVVEAFAPAHVVEFFATTDGQAVLANVSGAKVGSKGRPLPGAGRIEL
MAB_2348|M.abscessus_ATCC_1997 LWRRVTEKFDPAHVVEFFATTDGEAVLANVSGTKVGSKGRPLPGGGKVRL
** **.: * **:*******.**.*:**** * *:.******** .: *
Mvan_3301|M.vanbaalenii_PYR-1 AAYDPDDNLILEDDRGFVRRAETGEVGVLLAHPRGPVDPLASVKRGVFAP
Mflv_3517|M.gilvum_PYR-GCK AAYDPEDNLILEDERGFVRRAEVNEVGVLLAHPRGPVDPLASVKRGVFAP
MSMEG_3767|M.smegmatis_MC2_155 AAYDPDDDLILEDEQGFVRRAEADEVGVLLARPRGPVDPTAVVKRGVFAP
TH_2090|M.thermoresistible__bu GAYDPEDDLILEDERGFVRRAEPDEVGVLLARPRGPVDPTASIKRGVFAP
MMAR_2478|M.marinum_M GAYDAEHDLILENERGFVQIAEANQVGVLLAQSRGPIDPTASVKRGVFAP
MUL_1660|M.ulcerans_Agy99 GAYDAEHDLILENERGFVQIAEANQLGVLLAQSRGPIDPTASVKRGVFAP
Mb1710|M.bovis_AF2122/97 GAYDAEHDLILENDRGFVQVAGVNQVGVLLAQSRGPIDPTASVKRGVFAP
Rv1683|M.tuberculosis_H37Rv GAYDAEHDLILENDRGFVQVAGVNQVGVLLAQSRGPIDPTASVKRGVFAP
MLBr_01346|M.leprae_Br4923 GAYDAEQDLILENDRGFVQVADVNQIGVLLAASRGPIDPTASVKRGVFAP
MAV_3089|M.avium_104 GAYDTEHDLILENDRGFVQIAEPHQVGVLLAASNGPIDPSASVKRGVFAA
MAB_2348|M.abscessus_ATCC_1997 AAYDPVEDVIIEGEDGFVQIAEPGEVGLLLAKPPGDVDPTAAVRRGVFAP
.***. .::*:*.: ***: * ::*:*** . * :** * ::*****.
Mvan_3301|M.vanbaalenii_PYR-1 ADTWVSTEYLFRRDEDGDYWLVDNRGAAIHTARGMVFAATVNDAVGRLGA
Mflv_3517|M.gilvum_PYR-GCK ADTWVSTEYLFRRDEDGDYWLVDNRAAVIHTPRGVVYAATVNDAVGRLGA
MSMEG_3767|M.smegmatis_MC2_155 ADTWVSTEYLFRRDEDGDYWQVDNRSAVIRTERGPVFATTISDAAGRLNA
TH_2090|M.thermoresistible__bu ADTWVSTEYLFRRDEDGDFWLVGNRGAVIHTARGPVYAAAVNDAAGRIGP
MMAR_2478|M.marinum_M ADTWISTEYLFRRDEDGDFWLVGRRGSVARTARGMIYAEPVTDALGLIDA
MUL_1660|M.ulcerans_Agy99 ADTWISTEYLFRRDEDGDFWLVGRRGSVARTARGMIYAEPVTDALGLIDA
Mb1710|M.bovis_AF2122/97 ADTWISTDYLFWRDDDGDYWLAGGRGSVVRTARGMVYTEPVTNALGLITG
Rv1683|M.tuberculosis_H37Rv ADTWISTDYLFWRDDDGDYWLAGGRGSVVRTARGMVYTEPVTNALGLITG
MLBr_01346|M.leprae_Br4923 ADTWIATEYLLRRDYDGDYWLAGRRSSVVRTARGLVYTEPVTDALGFITG
MAV_3089|M.avium_104 GDTWISTEYLFYRDDDGDYWLAGRRGSVVHTPRGVVYAEPVTDALGCING
MAB_2348|M.abscessus_ATCC_1997 GDTWVSSEFLFRRDEDGDFWMLDGRGTAIRTAHGVVYAEATSNALGALGA
.***:::::*: ** ***:* . *.:. :* :* ::: . .:* * :
Mvan_3301|M.vanbaalenii_PYR-1 VDMAVTYGVEVEGQTLAVTALALCPGGSIPSADLSEALAALPVGNAPDIV
Mflv_3517|M.gilvum_PYR-GCK VDMAVTYGVESDGRTLAVTALSLRPGGSVPSADLSEALADIPVGTGPDIV
MSMEG_3767|M.smegmatis_MC2_155 VDMAVTYGVDLGDREVAVTALALRPGGSIPTADLTVALTDLPVGNPPDFV
TH_2090|M.thermoresistible__bu VDLAVTYPVPVGDRQLAVTALKLRPGGSLPSADLSEALADLPVGSPPDIV
MMAR_2478|M.marinum_M VDLAVTYEVSVGEHQLAVSAVTLRPGATITGADLTDAVAGMPIGLGPDLV
MUL_1660|M.ulcerans_Agy99 VDLAVTYEVSVGEHQLAVSAVTLRPGATITGADLTDAVAGMPIGLGPDLV
Mb1710|M.bovis_AF2122/97 VDLAVTYGVLVRGRHVAVSAVTLLPGATITAADLTEAVASMPVGLGPDIV
Rv1683|M.tuberculosis_H37Rv VDLAVTYGVLVRGRHVAVSAVTLLPGATITAADLTEAVASMPVGLGPDIV
MLBr_01346|M.leprae_Br4923 VDLAATYSVAVDDRELAVSAVTLLPGAAITAADLTEAVASMPVGLGPDIV
MAV_3089|M.avium_104 VDLAVTYNVPVGGHEVAVSAVTLLPGASITAADLTEACAKIPIGLGPDIV
MAB_2348|M.abscessus_ATCC_1997 IDLVATYPVETGETTVAVTAVVLRPGEALSPADLAEAFAAVAISERPDII
:*:..** * :**:*: * ** ::. ***: * : :.:. **::
Mvan_3301|M.vanbaalenii_PYR-1 HVVSDMTLTATFRPLAGPLQKQGIPKASR-NAWYLDPDSNRYKRLTVAVR
Mflv_3517|M.gilvum_PYR-GCK HVVTDMTLTTTFRPLAGPLQKQGVPKPSR-NAWYLDPDTHRYKRLTAAVR
MSMEG_3767|M.smegmatis_MC2_155 HVVPDMELSATYRPLVAPLRAAGIPKPHRRNSWYFDADTGTYKRLTQAVR
TH_2090|M.thermoresistible__bu HVVPSMELSATYRPLDGPLRAAGVPKASR-TAWFLDPETGRYRRLTAAVR
MMAR_2478|M.marinum_M HVVPTLSLSATYRPTVSALRAAGLPKPGR-QAWYFDADTSEFRRLTPAVR
MUL_1660|M.ulcerans_Agy99 HVVPTLSLSATYRPTVSALRAAGLPKPGR-QAWYFDADTSEFRRLTPAVR
Mb1710|M.bovis_AF2122/97 HVVPQLTLSGTYRPTVSALRANGIPKAGR-QAWYFNSGGNEYRRLTPAVR
Rv1683|M.tuberculosis_H37Rv HVVPQLTLSGTYRPTVSALRANGIPKAGR-QAWYFNSGGNEYRRLTPAVR
MLBr_01346|M.leprae_Br4923 HVVPELTLSATYRPIVGALRTAGIPKTGR-QVWYFDSASNQFRRMTPGVR
MAV_3089|M.avium_104 CVVPEMNLSATYRPTISALRAAGIPKAGR-QVWYFDAESGQYRRLTPAAR
MAB_2348|M.abscessus_ATCC_1997 KVVPNLPLSASYRPSTTHLRASGLPKPGR-QTWHLDPESGAYHRLTAATY
**. : *: ::** *: *:**. * *.::. ::*:* ..
Mvan_3301|M.vanbaalenii_PYR-1 SELAGIRQ--------
Mflv_3517|M.gilvum_PYR-GCK SELGGTQQ--------
MSMEG_3767|M.smegmatis_MC2_155 TELAGDDTDDAAVPTQ
TH_2090|M.thermoresistible__bu SELVGRRRRADAESTG
MMAR_2478|M.marinum_M AELSGEAPADA-----
MUL_1660|M.ulcerans_Agy99 AELSGEAPADA-----
Mb1710|M.bovis_AF2122/97 TELTGQHRRGNA----
Rv1683|M.tuberculosis_H37Rv TELTGQHRRGNA----
MLBr_01346|M.leprae_Br4923 AELAGKHTHTHA----
MAV_3089|M.avium_104 AELSGGRS--------
MAB_2348|M.abscessus_ATCC_1997 EALRGAVL--------
* *