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M. smegmatis MC2 155 MSMEG_4988 (-)

annotation: integral membrane protein
coordinates: 5083905 - 5085776
length: 623

TLVARDPARAEVEAPDSRTSESVRPRSRAERVALPLLLAGTALLYLWNLSISGWANPFYSAAAQAGASDW
IAMLFGSSDPANAITVDKTPAALWVIDLSVRLFGLSSWSVLLPQALEGIAAVAVLYAAVRRAAGWHAAVL
AGAVLALTPVAALIFRFNNPDALLVLLLVVAAYCVQRGIEKDASRWWFVAAGAAVGFGFLAKMLQAFLVL
PAFCAAALLAGDRPLRARIADLAAAGTAMVVSGGWYLVLVELWPAASRPYIGGSQNNSIVELALGYNGFG
RLTGAEVGGLGNSNFDVGAGRLFGWQMGADIAWLLPAALVCLVAGLIVTRRAPRTDRIRAALIIWGGWLV
VTAVVFSYMNGIVHPYYTVALAPAIGAVIGIGATSMWRHRNDIRVATAMAAAVAVTVILAAVLLARHNDP
MPWLRATVAVVGVAVAVLLLVVDLVHTRLVRPLAALTVLICLAGPGAYAVATAAAPHTGAIPSVGPSRGF
GGGPFSAPTPGEALTATLAADADNYTWAAAVVGSSNAAGYQLATGAPVMAVGGFNGTDPAPTLAEFEELV
AGRQIHYFIRSRIMGARPGHTPTGSQEAAEIARWVQAHFTPITIDDVTIYDLTQRVPNTPIS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4988--100% (623)integral membrane protein
M. smegmatis MC2 155MSMEG_4986-e-14346.04% (632) glycosyl transferase, family protein 39
M. smegmatis MC2 155MSMEG_0627-e-12344.70% (604) glycosyl transferase, family protein 39

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3821-3e-0525.00% (140) transmembrane protein
M. gilvum PYR-GCKMflv_2269-1e-15150.81% (614) glycosyl transferase family protein
M. tuberculosis H37RvRv3792-3e-0525.00% (140) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0927-1e-16047.45% (628) glycosyltransferase
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4427-0.068.24% (595) glycosyl transferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4988|M.smegmatis_MC2_155      MTLVARDPARAEVEAPDSRTSESVRPRSRAERVALPLLLAGTALLYLWNL
Mvan_4427|M.vanbaalenii_PYR-1       MTLLT--PAEKTQTRTQQRHGTRFHVFSR-QVMALGGLLVATGVLYLWNL
Mflv_2269|M.gilvum_PYR-GCK          MTTTVR-------TGVRSAPHPEADTRPRWVTPALLALLASTAVLYLWGL
MAB_0927|M.abscessus_ATCC_1997      MSVLS-----------------TARGRAR-EPLSVTLLLVGTAVAYLINL
Mb3821|M.bovis_AF2122/97            MPSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAI
Rv3792|M.tuberculosis_H37Rv         MPSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAI
                                    *.                         .     :   : ....:  *  :

MSMEG_4988|M.smegmatis_MC2_155      SISGWANPFYSAAAQAGASDWIAMLFGSSDPANAITVDKTPAALWVIDLS
Mvan_4427|M.vanbaalenii_PYR-1       GASGWANAYYSAAVQAGSQNWTAMLFGSSDAANAITVDKPPAALWVMDLS
Mflv_2269|M.gilvum_PYR-GCK          GSSGWANQYYAAAAQAGTQDWKAWLFGSLDAGNAITVDKPPASLWVMALS
MAB_0927|M.abscessus_ATCC_1997      ASNGWANSFYSAAVQAGSVSWKAGFFGSSDAANSITVDKPPAALWLMELS
Mb3821|M.bovis_AF2122/97            ARVEWPAFPSSNQLHALT---TVGQVGCLAGLVGIGWLWRHGRFRRLARL
Rv3792|M.tuberculosis_H37Rv         ARVEWPAFPSSNQLHALT---TVGQVGCLAGLVGIGWLWRHGRFRRLARL
                                    .   *.    :   :* :    .  .*.     .*      . :  :   

MSMEG_4988|M.smegmatis_MC2_155      VRLFGLSSWSVLLPQALEGIAAVAVLYAAVRRAAGWHAAVLAGAVLALTP
Mvan_4427|M.vanbaalenii_PYR-1       ARLFGFNPWSVLVPQALMGVAAVAVLYAAVRRASGPGAGLLAGAVLALTP
Mflv_2269|M.gilvum_PYR-GCK          GRVFGFSPFTMLLPQALMGVASVAVLVAAVRRLSGPGAGLIAGAALAVTP
MAB_0927|M.abscessus_ATCC_1997      VRVFGLSGWSILVPQVLLGVASVGLLYATVRRYFGHRAGLLAGLVLAVTP
Mb3821|M.bovis_AF2122/97            GGLVLVSAFTVVTLGMPLGATKLYLFGISVDQQFRTEYLTRLTDTAALRD
Rv3792|M.tuberculosis_H37Rv         GGLVLVSAFTVVTLGMPLGATKLYLFGISVDQQFRTEYLTRLTDTAALRD
                                      :. .. ::::      * : : ::  :* :            . *:  

MSMEG_4988|M.smegmatis_MC2_155      VAALIFRFNNPDALLVLLLVVAAYCVQRGIEK----DASRWWFVAAGAAV
Mvan_4427|M.vanbaalenii_PYR-1       VAALMFRFNNPDALLVLLLVIAEYCTQRACEK----GASRWWLIAAGVAI
Mflv_2269|M.gilvum_PYR-GCK          VAALMFRYNNPDALLVLLLVVAAYLMVRAIQT----GGTR-WVVLVGVVL
MAB_0927|M.abscessus_ATCC_1997      VAVLMFRFNNPDALLVFLMIAAVWAMMRAVED----GRTR-WMLLVGVFV
Mb3821|M.bovis_AF2122/97            MTYIGLPPFYPPGWFWIGGRAAALTGTPAWEMFKPWAITSMAIAVAVALV
Rv3792|M.tuberculosis_H37Rv         MTYIGLPPFYPPGWFWIGGRAAALTGTPAWEMFKPWAITSMAIAVAVALV
                                    :: : :    * . : :    *      . :       :   .  . . :

MSMEG_4988|M.smegmatis_MC2_155      GFGFLAKMLQAFLVLPAFCAAALLAGDRPLRARIADLAAAGTAMVVSGGW
Mvan_4427|M.vanbaalenii_PYR-1       GFGFLTKMLQALLVLPAFAAAYLLAGHRPVGRRILDALTAAGAAVVSAGW
Mflv_2269|M.gilvum_PYR-GCK          GVAFLTKMLQAFLVVPGLALAFLVAAPVGVWARVGKLAAGGVAMIATAGS
MAB_0927|M.abscessus_ATCC_1997      GFGFLTKQLQVLLVIPPVAVTYLIAGPAGAGKRLAQLVGSAAAAVVSAGW
Mb3821|M.bovis_AF2122/97            LWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPMLVLTWSGL
Rv3792|M.tuberculosis_H37Rv         LWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPMLVLTWSGL
                                        : :   .:**    . . *  .       :          :. .* 

MSMEG_4988|M.smegmatis_MC2_155      YLVLVELWPAASRPYIGGSQNNSIVELALGYNGFGRLTGAEVG-------
Mvan_4427|M.vanbaalenii_PYR-1       YLLLVELWPKESRPYIGGSQTNSITELTLGYNGIGRLTGNEPG-------
Mflv_2269|M.gilvum_PYR-GCK          FLTLVSVWPADARPYIGGSTDNSLLQLALGYNGIQRVMGGQGGPGGPPGG
MAB_0927|M.abscessus_ATCC_1997      WIAAVELWPPGSRPWIGGSPDNSILELTLGYNGLGRINGNETGSASGPRE
Mb3821|M.bovis_AF2122/97            GARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAG-----
Rv3792|M.tuberculosis_H37Rv         GARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAG-----
                                         . *.    . :  .   :   * :.*..:  :             

MSMEG_4988|M.smegmatis_MC2_155      GLGN------------SNFDVG----AGRLFGWQMGADIAWLLPAALVCL
Mvan_4427|M.vanbaalenii_PYR-1       GLGN------------LNHDVG----WGRLFGFGMGADIAWLLPAAVICL
Mflv_2269|M.gilvum_PYR-GCK          GLGGPPAGGPGGPGGGANLFFGGEPDIGRLFGASMGAEASWLLPAALIGL
MAB_0927|M.abscessus_ATCC_1997      GMYG------------FGGHFGSEPGIGRLFQPALGGQIAWLLPTALLLA
Mb3821|M.bovis_AF2122/97            ----------------SRLQSGIKAAVDPLCRLAVVGAIAAAIGSTTWLP
Rv3792|M.tuberculosis_H37Rv         ----------------SRLQSGIKAAVDPLCRLAVVGAIAAAIGSTTWLP
                                                         *     . *    : .  :  : ::    

MSMEG_4988|M.smegmatis_MC2_155      VAGLIVTRRAPRTDRIRAALIIWGGWLVVTAVVFSYMNGIVHP------Y
Mvan_4427|M.vanbaalenii_PYR-1       AAGFVLTRGRPRTDRTRASLILWAGWLVVTALVFSYMNGIVHP------Y
Mflv_2269|M.gilvum_PYR-GCK          VAALWITRRAARTDAIRAGLLLWGGWVLVTGVVFSYMDGIIHP------Y
MAB_0927|M.abscessus_ATCC_1997      ILGIVLLRNNSRTDARRAVLIVFGLWILTTGIVFSYMQGIFHP------Y
Mb3821|M.bovis_AF2122/97            YLLRAARDPVSDTGSAQHYLPADGAALTFPMLQFSLLGAICLLGTLWLVM
Rv3792|M.tuberculosis_H37Rv         YLLRAARDPVSDTGSAQHYLPADGAALTFPMLQFSLLGAICLLGTLWLVM
                                              . *.  :  *   .  :  . : ** : .*          

MSMEG_4988|M.smegmatis_MC2_155      YTVALAPAIGAVIGIGATSMWRHRNDIRVATAMAAAVAVTVILAAVLLAR
Mvan_4427|M.vanbaalenii_PYR-1       YTVALAPAIGAGIGIGSNLLWQNRRDVRSATAMAGAVLVTTVLAAVLLAR
Mflv_2269|M.gilvum_PYR-GCK          YTVALAPGIAALIGISVVTLWRGRGLFAPRLILAAMSAVTGVWAFVLLDR
MAB_0927|M.abscessus_ATCC_1997      YSMALTPAVAALVGAGSVLGWREREKSWVRACLAALLMLTAAMAWLLLGR
Mb3821|M.bovis_AF2122/97            RARSSAPAGALAIGVLAVYLWSLLSMLATLARTTLLSFRLQPTLSVLLVA
Rv3792|M.tuberculosis_H37Rv         RARSSAPAGALAIGVLAVYLWSLLSMLATLARTTLLSFRLQPTLSVLLVA
                                     : : :*. .  :*      *            :           :**  

MSMEG_4988|M.smegmatis_MC2_155      HNDPMPWLRATVAVVGVAVAVLLLVVDLVHTRLVRPLAALTVLICLAGPG
Mvan_4427|M.vanbaalenii_PYR-1       HSDWMPWLRAAVAVGGVGATVLLLVVGRLHRRAARLVAALAVTSCLAGPA
Mflv_2269|M.gilvum_PYR-GCK          TPEWQPWLRWVVLVGSIAVAVVFSAGAHRLGRATVAVAAAAIVLGAAAPL
MAB_0927|M.abscessus_ATCC_1997      SPEFQPWLRWAILIL-----ALLALIGLAMSRCPKAVVVAALVAALAGPV
Mb3821|M.bovis_AF2122/97            AGAFG-FVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRPDLTI
Rv3792|M.tuberculosis_H37Rv         AGAFG-FVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRPDLTI
                                          ::. .  :      .:                  .       . 

MSMEG_4988|M.smegmatis_MC2_155      AYAVATAAAPHTG-AIPSVG---PSR------GF----------------
Mvan_4427|M.vanbaalenii_PYR-1       AFSVATAASPHSG-ALPSVG---PSRHGGPPGGFP---------------
Mflv_2269|M.gilvum_PYR-GCK          AYALETALHSHAGGAMAMSG---PARDS----GFG---------------
MAB_0927|M.abscessus_ATCC_1997      AYSAATIATPHGG-ALPSAG---PEVNGGGFPEFPDMPERPHRAEFEPAS
Mb3821|M.bovis_AF2122/97            AYTDTDGYGQRGDRRPPGSEKYYPAIDAAIRRVTGK--------------
Rv3792|M.tuberculosis_H37Rv         AYTDTDGYGQRGDRRPPGSEKYYPAIDAAIRRVTGK--------------
                                    *::       : .   .      *                          

MSMEG_4988|M.smegmatis_MC2_155      --GGGPFSAPTPGEALTATLAADADNYTWAAAVVGSSNAAGYQLATGAPV
Mvan_4427|M.vanbaalenii_PYR-1       --GGGLLSSPNPHPDLIRLLTTDAGQFTWAAAVVGSNNAAGYQLASGAPV
Mflv_2269|M.gilvum_PYR-GCK          --GPGGPAGPDGDNTELQELVRSADN-RWAAAGVGSMLTGDLQLRTGASV
MAB_0927|M.abscessus_ATCC_1997      KRGGSLLDGSDPGPNIVAALNDNADRYTWVAAAIGSNQASGYQLATRRPV
Mb3821|M.bovis_AF2122/97            RRDRTVVLTADYSFLSYYPYWGFQGLTPHYANPLAQFDKRATQIDSWSGL
Rv3792|M.tuberculosis_H37Rv         RRDRTVVLTADYSFLSYYPYWGFQGLTPHYANPLAQFDKRATQIDSWSGL
                                      .      .              .     *  :..      *: :   :

MSMEG_4988|M.smegmatis_MC2_155      MAVGGFNGT-DPAPTLAEFEELVAGRQIHYFIR-SRIMGARPGHTPTGSQ
Mvan_4427|M.vanbaalenii_PYR-1       MAVGGFNGT-DPSPTLEQFVADVQAGRIHYFVVGPRLMMGRSG---TETT
Mflv_2269|M.gilvum_PYR-GCK          MAIGGFTGG-DNAPTLEQFQQYVADGQVRYFIA--GGHGGPGG----GAR
MAB_0927|M.abscessus_ATCC_1997      MPIGGFNGT-DPSPTLAQFQQYVADGQIHYFIDGERGSHGDEGFGPPGSE
Mb3821|M.bovis_AF2122/97            STADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDVYPNQPNVRRYT
Rv3792|M.tuberculosis_H37Rv         STADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDVYPNQPNVRRYT
                                     . . * .  *  *        :     . :                   

MSMEG_4988|M.smegmatis_MC2_155      EAAEIARWVQAHFTPITIDDVTIYDLTQRVPNTPIS-
Mvan_4427|M.vanbaalenii_PYR-1       ESAAIRDWVEARYLELTVDGTVVYDLTQGAGNLTGGA
Mflv_2269|M.gilvum_PYR-GCK          SASQITAWVTQTFAPRDVGGTAVYDLQR---------
MAB_0927|M.abscessus_ATCC_1997      TSKSIREWVQRTFTKKTIDDVEVYDLTGH--------
Mb3821|M.bovis_AF2122/97            VDLRTALFADPRFVVEDIGPFVLAIRKPQESA-----
Rv3792|M.tuberculosis_H37Rv         VDLRTALFADPRFVVEDIGPFVLAIRKPQESA-----
                                           :.   :    :.   :