For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TTSVIVAGARTPVGKLMGSLKDFSGSDLGGVAIAGALEKAFPNIENPARLVEYVIMGQVLTAGAGQMPAR QAAVAGGIPWDVASLTINKMCLSGIDAIALADQLIRAGEFDVVVAGGQESMTQAPHLLMNSRSGYKYGDV TVLDHLAYDGLHDAFTDQPMGALTEQRNDVDQFTRAQQDEVAATSHQKAARAWKDGVFADEVVPVRIPQR KGDPIEFTEDEGIRADTTAESLGGLKPAFRKDGTITAGSASQISDGACAVVVMNKAKAEELGLTWLCEIG AHGVVAGPDSTLQSQPANAIKKAAEKEGISLDQLDVLEINEAFAAVALASTKELGVDPEKVNVNGGAIAI GHPIGMSGARITLHAALELARRGGKYAVAALCGAGGQGDALILRRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4305 | - | - | 100% (397) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4891 | - | e-148 | 69.47% (393) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4589 | - | 2e-65 | 38.64% (396) | acetyl-CoA acetyltransferases |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1358 | fadA4 | 0.0 | 84.40% (391) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_2340 | - | 0.0 | 88.28% (401) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv1323 | fadA4 | 0.0 | 84.40% (391) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | MLBr_01158 | fadA4 | 0.0 | 82.03% (395) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_1463 | - | 1e-174 | 79.34% (392) | acetyl-CoA acetyltransferase FadA |
| M. marinum M | MMAR_4075 | fadA4 | 0.0 | 85.32% (395) | acetyl-CoA acetyltransferase FadA4 |
| M. avium 104 | MAV_1544 | - | 0.0 | 86.58% (395) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_4920 | - | 0.0 | 88.13% (396) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_0255 | - | 1e-59 | 38.38% (396) | acetyl-CoA acetyltransferase |
| M. ulcerans Agy99 | MUL_3938 | fadA4 | 0.0 | 85.32% (395) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4305|M.vanbaalenii_PYR-1 -------------------MTTSVIVAGARTPVGKLMGSLKDFSGSDLGG
Mflv_2340|M.gilvum_PYR-GCK -------------------MTTSVIVAGARTPVGKLMGSLKEFSGSDLGA
MSMEG_4920|M.smegmatis_MC2_155 MRQLCRLIIVNTAIWGGSNMTTSVIVAGARTPVGKLMGSLKDFSGTDLGA
MMAR_4075|M.marinum_M -------------------MTTSVIVAGARTPIGRLMGSLKDFSASDLGA
MUL_3938|M.ulcerans_Agy99 -------------------MTTSVIVAGARTPIGRLMGSLKDFSASDLGA
Mb1358|M.bovis_AF2122/97 -----------------------MIVAGARTPIGKLMGSLKDFSASELGA
Rv1323|M.tuberculosis_H37Rv -----------------------MIVAGARTPIGKLMGSLKDFSASELGA
MAV_1544|M.avium_104 -------------------MTTSVIVAGARTPIGKLMGSLKDFSASDLGA
MLBr_01158|M.leprae_Br4923 -------------------MTTSVIVTGARTPIGKLMGSLKDFSASDLGA
MAB_1463|M.abscessus_ATCC_1997 ----------------MAATNRSVIVAGARTPVGRFQGSLKDFSGAQLGG
TH_0255|M.thermoresistible__bu -------------------MRETVIVEAVRTAVGKRNGALADVHAADLSA
:** ..**.:*: *:* :. .::*..
Mvan_4305|M.vanbaalenii_PYR-1 VAIAGALEKAFPNIENPARLVEYVIMGQVLTAG-AGQMPARQAAVAGGIP
Mflv_2340|M.gilvum_PYR-GCK VAIKGALEKAN----VDASAVEYVIMGQVLSAG-AGQMPARQAAVAAGIP
MSMEG_4920|M.smegmatis_MC2_155 IAIRAALEKAN----VPASMVEYVIMGQVLTAG-AGQMPARQAAVAAGIP
MMAR_4075|M.marinum_M IAIKAALEKGN----VPASLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
MUL_3938|M.ulcerans_Agy99 IAIKAALEKGN----VPASLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
Mb1358|M.bovis_AF2122/97 IAIKGALEKAN----VPASLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
Rv1323|M.tuberculosis_H37Rv IAIKGALEKAN----VPASLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
MAV_1544|M.avium_104 IAIAGALEKAN----VPADLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
MLBr_01158|M.leprae_Br4923 ITIAAALKKAN----VAPSIVQYVIIGQVLTAG-AGQMPARQAAVAAGIG
MAB_1463|M.abscessus_ATCC_1997 IAIAGALAKAG----VAPSAVDYVIMGQVLTAG-AGQMPARQAAVAGGIG
TH_0255|M.thermoresistible__bu VVLSELVERAG----IDPELIDDVIWGCVSQVGDQSSNIGRYAVLAAGWP
:.: : :. . :: ** * * .* .. .* *.:*.*
Mvan_4305|M.vanbaalenii_PYR-1 WDVASLTINKMCLSGIDAIALADQLIRAGEFDVVVAGGQESMTQAPHLLM
Mflv_2340|M.gilvum_PYR-GCK WDVASLTINKMCLSGIDAIALADQLIRAGEFDVIVAGGQESMTQAPHLLM
MSMEG_4920|M.smegmatis_MC2_155 WDVAALSINKMCLSGIDAIALADQLIRAGEFDVIVAGGQESMSQAPHLLP
MMAR_4075|M.marinum_M WDVPALTINKMCLSGIDAIALADQLIRAGEFEVVVAGGQESMTKAPHLLM
MUL_3938|M.ulcerans_Agy99 WDVTALTINKMCLSGIDAIALADQLIRAGEFEVVVAGGQESMTKAPHLLM
Mb1358|M.bovis_AF2122/97 WDVPALTINKMCLSGIDAIALADQLIRAREFDVVVAGGQESMTKAPHLLM
Rv1323|M.tuberculosis_H37Rv WDVPALTINKMCLSGIDAIALADQLIRAREFDVVVAGGQESMTKAPHLLM
MAV_1544|M.avium_104 WDVPALSINKMCLSGIDAIALADQLIRAGEFDVVVAGGQESMTKAPHLLM
MLBr_01158|M.leprae_Br4923 WDVPALTINKMCLSGLDAIALADQLIRAGEFDVVVAGGQESMTKAPHLLM
MAB_1463|M.abscessus_ATCC_1997 MDVPALTINKVCLSGVDAIALADQLIRAGEFEVVVAGGQESMTNAPHLLP
TH_0255|M.thermoresistible__bu ETIPGTTVNRACGSSQQALDFAVHAVMSGQQDVVVAGGVEVMSRVP-LGA
:.. ::*: * *. :*: :* : : : : :*:**** * *:..* *
Mvan_4305|M.vanbaalenii_PYR-1 NSRSGYKYGDVTVLDHLAYDGLHDAFTDQPMGALTEQRNDVDQFTRAQQD
Mflv_2340|M.gilvum_PYR-GCK NSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDADKFTRAEQD
MSMEG_4920|M.smegmatis_MC2_155 KSREGYKYGDATLVDHLAYDGLHDVFTDQPMGALTEQRNDVDKFTRAEQD
MMAR_4075|M.marinum_M DSRSGYKYGDVTVLDHMAYDGLHDAFTDQPMGALTEQRNDVDGFTRRQQD
MUL_3938|M.ulcerans_Agy99 DSRPGYKYGDVTVLDHMAYDGLHDAFTDQPMGALTEQRNDVDGFTRRQQD
Mb1358|M.bovis_AF2122/97 NSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDMFTRSEQD
Rv1323|M.tuberculosis_H37Rv NSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDMFTRSEQD
MAV_1544|M.avium_104 DSRAGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDKFTREEQD
MLBr_01158|M.leprae_Br4923 DSRSGYKYGDVTIVDHLAYDGLHDVFTNQPMGALTEQRNDVEKFTRQEQD
MAB_1463|M.abscessus_ATCC_1997 KSRAGFKYGDVTLIDHMAFDGLHDAFTDQAMGLLTEQRNASDKFTREEQD
TH_0255|M.thermoresistible__bu ARATGMPYG-PKVLERYDNFGFNQGIS---AELIAERWN----LSRTRLD
* ** .:::: *::: :: ::*: * ::* . *
Mvan_4305|M.vanbaalenii_PYR-1 EVAATSHQKAARAWKDGVFADEVVPVRIPQRKGDPIEFTEDEGIRADTTA
Mflv_2340|M.gilvum_PYR-GCK SYAAESHQKAARAWKDGVYADEVVPVKIPQRKGDPIEFAEDEGIRADTTA
MSMEG_4920|M.smegmatis_MC2_155 EYAAQSHQKAAAAWKDGVFADEVVPVSIPQRKGDPIEFAEDEGIRANTTA
MMAR_4075|M.marinum_M EYSAASHQKAAAAWKDGVFADEVVPVSVPQRKGDPLQFSEDEGIRANTTA
MUL_3938|M.ulcerans_Agy99 EYSAASHQKAAAAWKDGVFADEVVPVSVPQRKGDPLQFSEDEGIRANTTA
Mb1358|M.bovis_AF2122/97 EYAAASHQKAAAAWKDGVFADEVIPVNIPQRTGDPLQFTEDEGIRANTTA
Rv1323|M.tuberculosis_H37Rv EYAAASHQKAAAAWKDGVFADEVIPVNIPQRTGDPLQFTEDEGIRANTTA
MAV_1544|M.avium_104 QYAARSHQRAAAAWKDGVFTDEVVPVNIPQRKGDPLQFTEDEGIRANTTA
MLBr_01158|M.leprae_Br4923 EFAARSHQKAAAAWKDGVFADEVVPVSIPQSKGDSLQFTEDEGIRANTSA
MAB_1463|M.abscessus_ATCC_1997 EFAARSHQNAARGWKDGAFADEVVPVRIPQRKGDPIEFAEDEGIRADTTA
TH_0255|M.thermoresistible__bu EYSAQSHERAAAAQSSGAFKDQIVPVFT-----DDAVVTEDEGIRRGTTV
. :* **:.** . ..*.: *:::** * .:****** .*:.
Mvan_4305|M.vanbaalenii_PYR-1 ESLGGLKPAFRKDGTITAGSASQISDGACAVVVMNKAKAEELGLTWLCEI
Mflv_2340|M.gilvum_PYR-GCK ESLGGLRPAFRKDGTITAGSASQISDGACAVVVMNKAKAEELGLTWLCEI
MSMEG_4920|M.smegmatis_MC2_155 ESLAGLKPAFRKDGTITAGSASQISDGAAAVIVMNKAKAEELGLTWLAEI
MMAR_4075|M.marinum_M DSLACLKPAFRKDGTVTAGSSSQISDGAAAVVVMSKEKAQELGLTWLVEI
MUL_3938|M.ulcerans_Agy99 DSLAGLKPAFRKDGTVTAGSSSQISDGAAAVVVMSKEKAQELGLTWLVEI
Mb1358|M.bovis_AF2122/97 AALAGLKPAFRGDGTITAGSASQISDGAAAVVVMNQEKAQELGLTWLAEI
Rv1323|M.tuberculosis_H37Rv AALAGLKPAFRGDGTITAGSASQISDGAAAVVVMNQEKAQELGLTWLAEI
MAV_1544|M.avium_104 ESLAGLKPAFRKDGTITAGSASQISDGAAAVVVMSKAKAQQLGLSWLAEI
MLBr_01158|M.leprae_Br4923 ESLAGLKPAFRCGGTITPGSASQISDGAATVVVMNKEKAQQLGLTWLVEI
MAB_1463|M.abscessus_ATCC_1997 ASLAGLRPAFSKDGTITAGSSSPISDGACAVVVMSKERAEREGLEWLAEI
TH_0255|M.thermoresistible__bu EKLATLKPAFTENGVIHAGNSSQISDGAAALLVMTAETAVTLGLTPIVRY
*. *:*** .*.: .*.:* *****.:::**. * ** : .
Mvan_4305|M.vanbaalenii_PYR-1 GAHGVVAGPDSTLQSQPANAIKKAAEKEGISLDQLDVLEINEAFAAVALA
Mflv_2340|M.gilvum_PYR-GCK GAHGVAAGPDSTLQSQPANAIRKALAKEGIGVDDLSVIEINEAFAAVALA
MSMEG_4920|M.smegmatis_MC2_155 GAHGVVAGPDSTLQSQPANAIKKAITREGITVDQLDVIEINEAFAAVALA
MMAR_4075|M.marinum_M GAHGVAAGPDSTLQSQPANAIKKALDKEGITADQLDVVEINEAFAAVALA
MUL_3938|M.ulcerans_Agy99 GAHGVAAGPDSTLQSQPANAIKKALDKEGITADQLDVVEINEAFAAVALA
Mb1358|M.bovis_AF2122/97 GAHGVVAGPDSTLQSQPANAINKALDREGISVDQLDVVEINEAFAAVALA
Rv1323|M.tuberculosis_H37Rv GAHGVVAGPDSTLQSQPANAINKALDREGISVDQLDVVEINEAFAAVALA
MAV_1544|M.avium_104 GAHGVVAGPDSTLQSQPANAIKKALGREGISVDQLDVVEINEAFAAVALA
MLBr_01158|M.leprae_Br4923 GAHGVVAGPDSTLQSQPANAIKKAVDREGISVEQLDVVEINEAFAAVALA
MAB_1463|M.abscessus_ATCC_1997 GAHGVVAGPDSSLQLQPANAIRKACEREGISPEQLDLVEINEAFALVGLA
TH_0255|M.thermoresistible__bu RAGAVTGADPVLMLTGPIPATEKVLRKTGLNIDDIGVFEVNEAFAPVPLA
* .*... : * * .*. : *: :::.:.*:***** * **
Mvan_4305|M.vanbaalenii_PYR-1 STKELGVDP----EKVNVNGGAIAIGHPIGMSGARITLHAALELARRGGK
Mflv_2340|M.gilvum_PYR-GCK SARELGLDEATVAEKVNTNGGAIAIGHPIGMSGARITLHAALELARKGSG
MSMEG_4920|M.smegmatis_MC2_155 STKELGVDP----AKVNVNGGAIAIGHPIGMSGARIALHAALELARRGSG
MMAR_4075|M.marinum_M STKELGLDP----EIVNVNGGAIAFGHPIGMSGARITLHVALELARRGSG
MUL_3938|M.ulcerans_Agy99 STKELGLDP----EIVNVNGGAIAFGHPIGMSGARITLHVALELARRGSG
Mb1358|M.bovis_AF2122/97 SIRELGLNP----QIVNVNGGAIAVGHPLGMSGTRITLHAALQLARRGSG
Rv1323|M.tuberculosis_H37Rv SIRELGLNP----QIVNVNGGAIAVGHPLGMSGTRITLHAALQLARRGSG
MAV_1544|M.avium_104 STRELGVNP----DIVNVNGGAIAVGHPIGMSGARITLHAALELSRRGSG
MLBr_01158|M.leprae_Br4923 SARELGIAP----ELVNVNGGAIAVGHPLGMSGARITLHVALELARRGSG
MAB_1463|M.abscessus_ATCC_1997 SIKDLGIDP----EKVNVNGGAIAIGHPIGMSGARITLHLAQELKRRGGG
TH_0255|M.thermoresistible__bu WQAETGADP----AKLNPLGGAIALGHPLGASGAVLMTRMVHHMRANGIR
: * :* *****.***:* **: : : . .: .*
Mvan_4305|M.vanbaalenii_PYR-1 YAVAALCGAGGQGDALILRRP-
Mflv_2340|M.gilvum_PYR-GCK YAVAALCGAGGQGDALILRRP-
MSMEG_4920|M.smegmatis_MC2_155 YAVAALCGAGGQGDALVLRR--
MMAR_4075|M.marinum_M YGVAALCGGGGQGDALILRAG-
MUL_3938|M.ulcerans_Agy99 YGVAALCGGGGQGDALILRAG-
Mb1358|M.bovis_AF2122/97 VGVAALCGAGGQGDALILRAG-
Rv1323|M.tuberculosis_H37Rv VGVAALCGAGGQGDALILRAG-
MAV_1544|M.avium_104 YAVAALCGAGGQGDALILRAG-
MLBr_01158|M.leprae_Br4923 YGVAALCGAGGQGDALILRAV-
MAB_1463|M.abscessus_ATCC_1997 IGVAALCGGGGQGDALIVRV--
TH_0255|M.thermoresistible__bu YGLQTMCEGGGTANATVVELLA
.: ::* .** .:* ::.