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VIVAGARTPIGKLMGSLKDFSASELGAIAIKGALEKANVPASLVEYVIMGQVLTAGAGQMPARQAAVAAG IGWDVPALTINKMCLSGIDAIALADQLIRAREFDVVVAGGQESMTKAPHLLMNSRSGYKYGDVTVLDHMA YDGLHDVFTDQPMGALTEQRNDVDMFTRSEQDEYAAASHQKAAAAWKDGVFADEVIPVNIPQRTGDPLQF TEDEGIRANTTAAALAGLKPAFRGDGTITAGSASQISDGAAAVVVMNQEKAQELGLTWLAEIGAHGVVAG PDSTLQSQPANAINKALDREGISVDQLDVVEINEAFAAVALASIRELGLNPQIVNVNGGAIAVGHPLGMS GTRITLHAALQLARRGSGVGVAALCGAGGQGDALILRAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1323 | fadA4 | - | 100% (389) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv1074c | fadA3 | 3e-57 | 36.88% (404) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv3556c | fadA6 | 2e-49 | 33.93% (389) | acetyl-CoA acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1358 | fadA4 | 0.0 | 100.00% (389) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_2340 | - | 0.0 | 83.89% (391) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | MLBr_01158 | fadA4 | 0.0 | 87.11% (388) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_1463 | - | 1e-171 | 76.74% (387) | acetyl-CoA acetyltransferase FadA |
| M. marinum M | MMAR_4075 | fadA4 | 0.0 | 89.20% (389) | acetyl-CoA acetyltransferase FadA4 |
| M. avium 104 | MAV_1544 | - | 0.0 | 91.26% (389) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_4920 | - | 0.0 | 85.53% (387) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_0255 | - | 4e-60 | 38.66% (388) | acetyl-CoA acetyltransferase |
| M. ulcerans Agy99 | MUL_3938 | fadA4 | 0.0 | 88.95% (389) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4305 | - | 0.0 | 84.40% (391) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2340|M.gilvum_PYR-GCK -------------------MTTSVIVAGARTPVGKLMGSLKEFSGSDLGA
Mvan_4305|M.vanbaalenii_PYR-1 -------------------MTTSVIVAGARTPVGKLMGSLKDFSGSDLGG
MSMEG_4920|M.smegmatis_MC2_155 MRQLCRLIIVNTAIWGGSNMTTSVIVAGARTPVGKLMGSLKDFSGTDLGA
Rv1323|M.tuberculosis_H37Rv -----------------------MIVAGARTPIGKLMGSLKDFSASELGA
Mb1358|M.bovis_AF2122/97 -----------------------MIVAGARTPIGKLMGSLKDFSASELGA
MAV_1544|M.avium_104 -------------------MTTSVIVAGARTPIGKLMGSLKDFSASDLGA
MLBr_01158|M.leprae_Br4923 -------------------MTTSVIVTGARTPIGKLMGSLKDFSASDLGA
MMAR_4075|M.marinum_M -------------------MTTSVIVAGARTPIGRLMGSLKDFSASDLGA
MUL_3938|M.ulcerans_Agy99 -------------------MTTSVIVAGARTPIGRLMGSLKDFSASDLGA
MAB_1463|M.abscessus_ATCC_1997 ----------------MAATNRSVIVAGARTPVGRFQGSLKDFSGAQLGG
TH_0255|M.thermoresistible__bu -------------------MRETVIVEAVRTAVGKRNGALADVHAADLSA
:** ..**.:*: *:* :. .::*..
Mflv_2340|M.gilvum_PYR-GCK VAIKGALEKAN----VDASAVEYVIMGQVLSAG-AGQMPARQAAVAAGIP
Mvan_4305|M.vanbaalenii_PYR-1 VAIAGALEKAFPNIENPARLVEYVIMGQVLTAG-AGQMPARQAAVAGGIP
MSMEG_4920|M.smegmatis_MC2_155 IAIRAALEKAN----VPASMVEYVIMGQVLTAG-AGQMPARQAAVAAGIP
Rv1323|M.tuberculosis_H37Rv IAIKGALEKAN----VPASLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
Mb1358|M.bovis_AF2122/97 IAIKGALEKAN----VPASLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
MAV_1544|M.avium_104 IAIAGALEKAN----VPADLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
MLBr_01158|M.leprae_Br4923 ITIAAALKKAN----VAPSIVQYVIIGQVLTAG-AGQMPARQAAVAAGIG
MMAR_4075|M.marinum_M IAIKAALEKGN----VPASLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
MUL_3938|M.ulcerans_Agy99 IAIKAALEKGN----VPASLVEYVIMGQVLTAG-AGQMPARQAAVAAGIG
MAB_1463|M.abscessus_ATCC_1997 IAIAGALAKAG----VAPSAVDYVIMGQVLTAG-AGQMPARQAAVAGGIG
TH_0255|M.thermoresistible__bu VVLSELVERAG----IDPELIDDVIWGCVSQVGDQSSNIGRYAVLAAGWP
:.: : :. . :: ** * * .* .. .* *.:*.*
Mflv_2340|M.gilvum_PYR-GCK WDVASLTINKMCLSGIDAIALADQLIRAGEFDVIVAGGQESMTQAPHLLM
Mvan_4305|M.vanbaalenii_PYR-1 WDVASLTINKMCLSGIDAIALADQLIRAGEFDVVVAGGQESMTQAPHLLM
MSMEG_4920|M.smegmatis_MC2_155 WDVAALSINKMCLSGIDAIALADQLIRAGEFDVIVAGGQESMSQAPHLLP
Rv1323|M.tuberculosis_H37Rv WDVPALTINKMCLSGIDAIALADQLIRAREFDVVVAGGQESMTKAPHLLM
Mb1358|M.bovis_AF2122/97 WDVPALTINKMCLSGIDAIALADQLIRAREFDVVVAGGQESMTKAPHLLM
MAV_1544|M.avium_104 WDVPALSINKMCLSGIDAIALADQLIRAGEFDVVVAGGQESMTKAPHLLM
MLBr_01158|M.leprae_Br4923 WDVPALTINKMCLSGLDAIALADQLIRAGEFDVVVAGGQESMTKAPHLLM
MMAR_4075|M.marinum_M WDVPALTINKMCLSGIDAIALADQLIRAGEFEVVVAGGQESMTKAPHLLM
MUL_3938|M.ulcerans_Agy99 WDVTALTINKMCLSGIDAIALADQLIRAGEFEVVVAGGQESMTKAPHLLM
MAB_1463|M.abscessus_ATCC_1997 MDVPALTINKVCLSGVDAIALADQLIRAGEFEVVVAGGQESMTNAPHLLP
TH_0255|M.thermoresistible__bu ETIPGTTVNRACGSSQQALDFAVHAVMSGQQDVVVAGGVEVMSRVP-LGA
:.. ::*: * *. :*: :* : : : : :*:**** * *:..* *
Mflv_2340|M.gilvum_PYR-GCK NSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDADKFTRAEQD
Mvan_4305|M.vanbaalenii_PYR-1 NSRSGYKYGDVTVLDHLAYDGLHDAFTDQPMGALTEQRNDVDQFTRAQQD
MSMEG_4920|M.smegmatis_MC2_155 KSREGYKYGDATLVDHLAYDGLHDVFTDQPMGALTEQRNDVDKFTRAEQD
Rv1323|M.tuberculosis_H37Rv NSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDMFTRSEQD
Mb1358|M.bovis_AF2122/97 NSRSGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDMFTRSEQD
MAV_1544|M.avium_104 DSRAGYKYGDVTVLDHMAYDGLHDVFTDQPMGALTEQRNDVDKFTREEQD
MLBr_01158|M.leprae_Br4923 DSRSGYKYGDVTIVDHLAYDGLHDVFTNQPMGALTEQRNDVEKFTRQEQD
MMAR_4075|M.marinum_M DSRSGYKYGDVTVLDHMAYDGLHDAFTDQPMGALTEQRNDVDGFTRRQQD
MUL_3938|M.ulcerans_Agy99 DSRPGYKYGDVTVLDHMAYDGLHDAFTDQPMGALTEQRNDVDGFTRRQQD
MAB_1463|M.abscessus_ATCC_1997 KSRAGFKYGDVTLIDHMAFDGLHDAFTDQAMGLLTEQRNASDKFTREEQD
TH_0255|M.thermoresistible__bu ARATGMPYG-PKVLERYDNFGFNQGIS---AELIAERWN----LSRTRLD
* ** .:::: *::: :: ::*: * ::* . *
Mflv_2340|M.gilvum_PYR-GCK SYAAESHQKAARAWKDGVYADEVVPVKIPQRKGDPIEFAEDEGIRADTTA
Mvan_4305|M.vanbaalenii_PYR-1 EVAATSHQKAARAWKDGVFADEVVPVRIPQRKGDPIEFTEDEGIRADTTA
MSMEG_4920|M.smegmatis_MC2_155 EYAAQSHQKAAAAWKDGVFADEVVPVSIPQRKGDPIEFAEDEGIRANTTA
Rv1323|M.tuberculosis_H37Rv EYAAASHQKAAAAWKDGVFADEVIPVNIPQRTGDPLQFTEDEGIRANTTA
Mb1358|M.bovis_AF2122/97 EYAAASHQKAAAAWKDGVFADEVIPVNIPQRTGDPLQFTEDEGIRANTTA
MAV_1544|M.avium_104 QYAARSHQRAAAAWKDGVFTDEVVPVNIPQRKGDPLQFTEDEGIRANTTA
MLBr_01158|M.leprae_Br4923 EFAARSHQKAAAAWKDGVFADEVVPVSIPQSKGDSLQFTEDEGIRANTSA
MMAR_4075|M.marinum_M EYSAASHQKAAAAWKDGVFADEVVPVSVPQRKGDPLQFSEDEGIRANTTA
MUL_3938|M.ulcerans_Agy99 EYSAASHQKAAAAWKDGVFADEVVPVSVPQRKGDPLQFSEDEGIRANTTA
MAB_1463|M.abscessus_ATCC_1997 EFAARSHQNAARGWKDGAFADEVVPVRIPQRKGDPIEFAEDEGIRADTTA
TH_0255|M.thermoresistible__bu EYSAQSHERAAAAQSSGAFKDQIVPVFT-----DDAVVTEDEGIRRGTTV
. :* **:.** . ..*.: *:::** * .:****** .*:.
Mflv_2340|M.gilvum_PYR-GCK ESLGGLRPAFRKDGTITAGSASQISDGACAVVVMNKAKAEELGLTWLCEI
Mvan_4305|M.vanbaalenii_PYR-1 ESLGGLKPAFRKDGTITAGSASQISDGACAVVVMNKAKAEELGLTWLCEI
MSMEG_4920|M.smegmatis_MC2_155 ESLAGLKPAFRKDGTITAGSASQISDGAAAVIVMNKAKAEELGLTWLAEI
Rv1323|M.tuberculosis_H37Rv AALAGLKPAFRGDGTITAGSASQISDGAAAVVVMNQEKAQELGLTWLAEI
Mb1358|M.bovis_AF2122/97 AALAGLKPAFRGDGTITAGSASQISDGAAAVVVMNQEKAQELGLTWLAEI
MAV_1544|M.avium_104 ESLAGLKPAFRKDGTITAGSASQISDGAAAVVVMSKAKAQQLGLSWLAEI
MLBr_01158|M.leprae_Br4923 ESLAGLKPAFRCGGTITPGSASQISDGAATVVVMNKEKAQQLGLTWLVEI
MMAR_4075|M.marinum_M DSLACLKPAFRKDGTVTAGSSSQISDGAAAVVVMSKEKAQELGLTWLVEI
MUL_3938|M.ulcerans_Agy99 DSLAGLKPAFRKDGTVTAGSSSQISDGAAAVVVMSKEKAQELGLTWLVEI
MAB_1463|M.abscessus_ATCC_1997 ASLAGLRPAFSKDGTITAGSSSPISDGACAVVVMSKERAEREGLEWLAEI
TH_0255|M.thermoresistible__bu EKLATLKPAFTENGVIHAGNSSQISDGAAALLVMTAETAVTLGLTPIVRY
*. *:*** .*.: .*.:* *****.:::**. * ** : .
Mflv_2340|M.gilvum_PYR-GCK GAHGVAAGPDSTLQSQPANAIRKALAKEGIGVDDLSVIEINEAFAAVALA
Mvan_4305|M.vanbaalenii_PYR-1 GAHGVVAGPDSTLQSQPANAIKKAAEKEGISLDQLDVLEINEAFAAVALA
MSMEG_4920|M.smegmatis_MC2_155 GAHGVVAGPDSTLQSQPANAIKKAITREGITVDQLDVIEINEAFAAVALA
Rv1323|M.tuberculosis_H37Rv GAHGVVAGPDSTLQSQPANAINKALDREGISVDQLDVVEINEAFAAVALA
Mb1358|M.bovis_AF2122/97 GAHGVVAGPDSTLQSQPANAINKALDREGISVDQLDVVEINEAFAAVALA
MAV_1544|M.avium_104 GAHGVVAGPDSTLQSQPANAIKKALGREGISVDQLDVVEINEAFAAVALA
MLBr_01158|M.leprae_Br4923 GAHGVVAGPDSTLQSQPANAIKKAVDREGISVEQLDVVEINEAFAAVALA
MMAR_4075|M.marinum_M GAHGVAAGPDSTLQSQPANAIKKALDKEGITADQLDVVEINEAFAAVALA
MUL_3938|M.ulcerans_Agy99 GAHGVAAGPDSTLQSQPANAIKKALDKEGITADQLDVVEINEAFAAVALA
MAB_1463|M.abscessus_ATCC_1997 GAHGVVAGPDSSLQLQPANAIRKACEREGISPEQLDLVEINEAFALVGLA
TH_0255|M.thermoresistible__bu RAGAVTGADPVLMLTGPIPATEKVLRKTGLNIDDIGVFEVNEAFAPVPLA
* .*... : * * .*. : *: :::.:.*:***** * **
Mflv_2340|M.gilvum_PYR-GCK SARELGLDEATVAEKVNTNGGAIAIGHPIGMSGARITLHAALELARKGSG
Mvan_4305|M.vanbaalenii_PYR-1 STKELGVDP----EKVNVNGGAIAIGHPIGMSGARITLHAALELARRGGK
MSMEG_4920|M.smegmatis_MC2_155 STKELGVDP----AKVNVNGGAIAIGHPIGMSGARIALHAALELARRGSG
Rv1323|M.tuberculosis_H37Rv SIRELGLNP----QIVNVNGGAIAVGHPLGMSGTRITLHAALQLARRGSG
Mb1358|M.bovis_AF2122/97 SIRELGLNP----QIVNVNGGAIAVGHPLGMSGTRITLHAALQLARRGSG
MAV_1544|M.avium_104 STRELGVNP----DIVNVNGGAIAVGHPIGMSGARITLHAALELSRRGSG
MLBr_01158|M.leprae_Br4923 SARELGIAP----ELVNVNGGAIAVGHPLGMSGARITLHVALELARRGSG
MMAR_4075|M.marinum_M STKELGLDP----EIVNVNGGAIAFGHPIGMSGARITLHVALELARRGSG
MUL_3938|M.ulcerans_Agy99 STKELGLDP----EIVNVNGGAIAFGHPIGMSGARITLHVALELARRGSG
MAB_1463|M.abscessus_ATCC_1997 SIKDLGIDP----EKVNVNGGAIAIGHPIGMSGARITLHLAQELKRRGGG
TH_0255|M.thermoresistible__bu WQAETGADP----AKLNPLGGAIALGHPLGASGAVLMTRMVHHMRANGIR
: * :* *****.***:* **: : : . .: .*
Mflv_2340|M.gilvum_PYR-GCK YAVAALCGAGGQGDALILRRP-
Mvan_4305|M.vanbaalenii_PYR-1 YAVAALCGAGGQGDALILRRP-
MSMEG_4920|M.smegmatis_MC2_155 YAVAALCGAGGQGDALVLRR--
Rv1323|M.tuberculosis_H37Rv VGVAALCGAGGQGDALILRAG-
Mb1358|M.bovis_AF2122/97 VGVAALCGAGGQGDALILRAG-
MAV_1544|M.avium_104 YAVAALCGAGGQGDALILRAG-
MLBr_01158|M.leprae_Br4923 YGVAALCGAGGQGDALILRAV-
MMAR_4075|M.marinum_M YGVAALCGGGGQGDALILRAG-
MUL_3938|M.ulcerans_Agy99 YGVAALCGGGGQGDALILRAG-
MAB_1463|M.abscessus_ATCC_1997 IGVAALCGGGGQGDALIVRV--
TH_0255|M.thermoresistible__bu YGLQTMCEGGGTANATVVELLA
.: ::* .** .:* ::.