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MRVAVDGNEAAVSVAYRLNEVCCIYPITPSSPMAELADEWSAAERTNVWGAVPTVVEMQSEGGAAGALHG ALQSGALTTTYTSSQGLLLMIPNMYKIAGELTSAVIHVAARSIAAQGLSIFGDHSDVMAVRQTGFALLGS ASVQEAHDLALVAQAATLATRVPFVHFFDGFRTSHEINTIETLSDDDLRSLVPEELIWAHRERALSPERP FIRGTAQNPDVYFQARETVNPFYARVPGVVEDLMARLGERTGRAMHIVDYSGHPEAERVLVLMGSGAETV QQTVAALVDRGERVGVVQVRLYRPFPTAAFLESLPATVRAVGVLDRTKEPGSIGEPLYLDVVAALAGACA DGDRAAMPRVTGGRYGLSSKEFTPAMVAGVLTELASERSRRQFTVGIDDDVSRTSVEYDPSFDIESPETV RAVFFGLGSDGTVSANKNTIKILGSEPGLHAQAYFVYDSKKSGSQTESHLRFGPHPIRAPYLVTAANFIG CHQFRFLDKVDVLGRAAPGATLLLNCRLPAERIWDALPRRVQEQILDKKITLYVVDADRIARAAGLPGRI NIVLQTCFFAISEVLPRDRAIDRIKDSVRKTYGNRGPDVLAAELAAVDGAVAGLQRIEVPTSATSIRVVP PPVPESAPEFVRTVTAEMMAGRGNALPVSALPVDGTYPSGTTAYEKRNISELVAVWDPDTCIQCGNCGFV CPHSVIRSKFYDGSQLAGAPADFDSAPLDAVGLPGARFSLQVYTEDCTGCGLCVEACPVVIPGPTATKAI NLGPAEPRMATERENVRFFESLPTNDRSRVDFGTVRGTQFLEPLFEFSGACAGCGETPYVKLLSQLFGDR LMVANATGCSSIYGGSLPTTPWTTNAEGRGPAWSNSLFEDNAEFGLGMRLAGDAHVRLARRRLTELRDTL GGAFVDAILDAPQRRESELAAQRERVAELRDRLACLDAAVTTDLLSVVDHLVRRSVWIVGGDGWAYDIGS GGLDHVLATGHNVNVLVLDTEVYSNTGGQMSKATPLGAVAKFAAAGKTVPLKDLALQAIAYGNVYVARVA MGADPQQTLQAFREAEAYDGPSLVIAYSQCIAHGIDMRLGMDQQYRAVASGHWPLLRFDPVMRAAGKNPF LLDSHRPRIALEHYRDRELRYRSLSNADPVEAERLLGLAEQAIEQRWNVYEAMASQQRSTKREHLRPDAR REP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4109 | - | - | 100% (1193) | pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3964 | - | 3e-09 | 28.57% (161) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2481c | - | 2e-08 | 32.48% (117) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. gilvum PYR-GCK | Mflv_2617 | - | 1e-09 | 28.57% (161) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. tuberculosis H37Rv | Rv2454c | - | 2e-08 | 32.48% (117) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1595 | - | 1e-08 | 32.48% (117) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. marinum M | MMAR_3408 | - | 0.0 | 77.05% (1194) | pyruvate ferredoxin/flavodoxin oxidoreductase family protein |
| M. avium 104 | MAV_1718 | orB | 3e-07 | 29.06% (117) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. smegmatis MC2 155 | MSMEG_4645 | orB | 5e-09 | 26.71% (161) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. thermoresistible (build 8) | TH_0355 | - | 3e-08 | 30.77% (117) | PROBABLE OXIDOREDUCTASE (BETA SUBUNIT) |
| M. ulcerans Agy99 | MUL_3725 | porB | 5e-08 | 30.77% (117) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 -MRVAVDGNEAAVSVAYRLNEVCCIYPITPSSPMAELADEWSAAERTNVW
MMAR_3408|M.marinum_M MTRTTVDGNEATASVAYRLNEVCCIYPITPSSPMAELADAWSNQNRPNIY
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 GAVPTVVEMQSEGGAAGALHGALQSGALTTTYTSSQGLLLMIPNMYKIAG
MMAR_3408|M.marinum_M GTVPTVVEMQSEGGAAGALHGSLQGGALTTTFTASQGLLLMIPNMYKIAG
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 ELTSAVIHVAARSIAAQGLSIFGDHSDVMAVRQTGFALLGSASVQEAHDL
MMAR_3408|M.marinum_M ELTSAVMHVAARSIAAQALSIFGDHQDVMAVRQTGFALLASASVQEAHDL
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 ALVAQAATLATRVPFVHFFDGFRTSHEINTIETLSDDDLRSLVPEELIWA
MMAR_3408|M.marinum_M ALIAQAATLRTRVPFVHFFDGFRTSHELNTIEVLTDDDLRALVPQELVLA
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 HRERALSPERPFIRGTAQNPDVYFQARETVNPFYARVPGVVEDLMARLGE
MMAR_3408|M.marinum_M HRDRALSPDRPSIRGTAQNPDTYFQARETVNPFYARVPEVVEGLLRELGE
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 RTGRAMHIVDYSGHPEAERVLVLMGSGAETVQQTVAALVDRGERVGVVQV
MMAR_3408|M.marinum_M RTGRPMHIVDYTGHPEAERVMVLMGSGGQTAAETVTALTERGERVGVAQI
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 RLYRPFPTAAFLESLPATVRAVGVLDRTKEPGSIGEPLYLDVVAALAGAC
MMAR_3408|M.marinum_M RLYRPFPAEALLAALPPTVRAIAVLDRTKEPGSQGEPLYLDVTAALAEAY
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 ADGDRAAMPRVTGGRYGLSSKEFTPAMVAGVLTELASERSRRQFTVGIDD
MMAR_3408|M.marinum_M SSGQRSSLPVVCGGRYGLSSKEFTPGMVAGVFAELAGQRPRTRFTVGIDD
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 DVSRTSVEYDPSFDIESPETVRAVFFGLGSDGTVSANKNTIKILGSEPGL
MMAR_3408|M.marinum_M DVSGTSISYDPDFDIETPATTKAVFFGMGSDGTVGANKNTIKILGGEEDI
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 HAQAYFVYDSKKSGSQTESHLRFGPHPIRAPYLVTAANFIGCHQFRFLDK
MMAR_3408|M.marinum_M YAQGYFVYDSKKSGSQTVSHLRFGPQPIRAPYLVQQASFVGCHHQRFLNK
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 VDVLGRAAPGATLLLNCRLPAERIWDALPRRVQEQILDKKITLYVVDADR
MMAR_3408|M.marinum_M VDVLGRAAHGAALLLNSARPPERVWDSLPAPVQQQIIDKRIRLYVVDAGK
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 IARAAGLPGRINIVLQTCFFAISEVLPRDRAIDRIKDSVRKTYGNRGPDV
MMAR_3408|M.marinum_M IAREVGLAGRINIVLQTCFFAIADVLPVDQAIAKIKASVAKTYAAHGADV
Mb2481c|M.bovis_AF2122/97 --------------------------------MTRSGDEAQLMTGVTGDL
Rv2454c|M.tuberculosis_H37Rv --------------------------------MTRSGDEAQLMTGVTGDL
MUL_3725|M.ulcerans_Agy99 ------------------------------------------MTSVIGNL
MAV_1718|M.avium_104 ------------------------------------------MTDVVGNL
Mflv_2617|M.gilvum_PYR-GCK -----------------------------------MTTARSEADRASAQL
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu -------------------------------------------------V
MAB_1595|M.abscessus_ATCC_1997 -------------------------------------MTDLLNEASTANG
Mvan_4109|M.vanbaalenii_PYR-1 LAAELAAVDGAVAGLQRIEVPTSATSIRVVPPPVPESAPEFVRTVTAEMM
MMAR_3408|M.marinum_M VAREVNAVDHALAGLHPVQVPDTVSSTRQLEPPVPQHAPEFVRTVTAEMI
Mb2481c|M.bovis_AF2122/97 AGTELGLTPS-LTKNAGVPTTDQPQKGK---DFTSDQEVRWCPGCG--DY
Rv2454c|M.tuberculosis_H37Rv AGTELGLTPS-LTKNAGVPTTDQPQKGK---DFTSDQEVRWCPGCG--DY
MUL_3725|M.ulcerans_Agy99 AGTNLGVTPV-LSKNTGVPTTDQPQKGK---DFTSDQEVRWCPGCG--DY
MAV_1718|M.avium_104 AGKDLGLTAK-LTKNDGVPTTDQPQKAK---DFTSDQEVRWCPGCG--DY
Mflv_2617|M.gilvum_PYR-GCK VGNDLGLTPGGLTKTSLVPKTDAPQKGK---DFTSDQEVRWCPGCG--DY
MSMEG_4645|M.smegmatis_MC2_155 --------------MSLVPTADQPQKAK---DFTSDQEVRWCPGCG--DY
TH_0355|M.thermoresistible__bu IGADLGLIPAGLPKTAGVPTTDQPQKGK---DFTSDQEVRWCPGCG--DY
MAB_1595|M.abscessus_ATCC_1997 TGSLNGLELG-LTANALVPTTDEEQKAK---DFTSDQEVRWCPGCG--DY
Mvan_4109|M.vanbaalenii_PYR-1 AGRGNALPVSALPVDGTYPSGTTAYEKRNISELVAVWDPDTCIQCGNCGF
MMAR_3408|M.marinum_M AGRGDGLPVSALPADGSYPSGTAAYEKRNISDLVAVWDPDTCIQCGNCSF
*. : : ::.: : * ** .:
Mb2481c|M.bovis_AF2122/97 VILNTIRN--FLPELGLRRENIVFISGIGCSSRFP--------YYLETYG
Rv2454c|M.tuberculosis_H37Rv VILNTIRN--FLPELGLRRENIVFISGIGCSSRFP--------YYLETYG
MUL_3725|M.ulcerans_Agy99 VILNTIRN--FLPELGLRRENIVFISGIGCSSRFP--------YYLETYG
MAV_1718|M.avium_104 VILNTIRN--FLPDLGLRRENIVFISGIGCSSRFP--------YYLETYG
Mflv_2617|M.gilvum_PYR-GCK VILNTIRN--FLPELGLRRENIAFVSGIGCSSRFP--------YYLETYG
MSMEG_4645|M.smegmatis_MC2_155 VILNTIRN--FLPELGLRRENIAFVSGIGCSSRFP--------YYLETYG
TH_0355|M.thermoresistible__bu VILNTIRN--FLPELGLRRENIAFISGIGCSSRFP--------YYLETYG
MAB_1595|M.abscessus_ATCC_1997 VILNTIRG--FLPELGLKRENIVFISGIGCSSRFP--------YYLDTYG
Mvan_4109|M.vanbaalenii_PYR-1 VCPHSVIRSKFYDGSQLAGAPADFDSAPLDAVGLPGARFSLQVYTEDCTG
MMAR_3408|M.marinum_M VCPHSVIRTTLYPRDRLDAAPATFASAPLDAVGLPDTRYTLQVYAEDCTG
* ::: : * * *. : :* * : *
Mb2481c|M.bovis_AF2122/97 FHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
Rv2454c|M.tuberculosis_H37Rv FHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
MUL_3725|M.ulcerans_Agy99 FHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
MAV_1718|M.avium_104 FHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
Mflv_2617|M.gilvum_PYR-GCK FHSIHGRAPTIATG---------------LALAREDLSVWVVTGDG----
MSMEG_4645|M.smegmatis_MC2_155 FHSIHGRAPTIATG---------------LALARPDLSVWVVTGDG----
TH_0355|M.thermoresistible__bu FHSIHGRAPTIATG---------------LALARPDLSVWVVTGDG----
MAB_1595|M.abscessus_ATCC_1997 MHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
Mvan_4109|M.vanbaalenii_PYR-1 CGLCVEACPVVIPGPTATKAINLGPAEPRMATERENVRFFESLPTNDRSR
MMAR_3408|M.marinum_M CNLCVEACPAVVPGKPVTKAINLAPREPLVAAARENIAFFETLPVANRSR
.*.: .* :* * :: .:
Mb2481c|M.bovis_AF2122/97 -DALSIGGNHLIHALRRNINVTILLFNNRIYGLTKGQYSPTSEVGKVTKS
Rv2454c|M.tuberculosis_H37Rv -DALSIGGNHLIHALRRNINVTILLFNNRIYGLTKGQYSPTSEVGKVTKS
MUL_3725|M.ulcerans_Agy99 -DALSIGGNHLIHAVRRNVNITILLFNNRIYGLTKGQYSPTSEVGKVTKS
MAV_1718|M.avium_104 -DALSIGGNHLIHALRRNVNITILLFNNRIYGLTKGQYSPTSEVGKITKS
Mflv_2617|M.gilvum_PYR-GCK -DALSIGGNHLIHALRRNINITILLFNNRIYGLTKGQYSPTSETGKVTKS
MSMEG_4645|M.smegmatis_MC2_155 -DSLSIGGNHLIHALRRNINITILLFNNRIYGLTKGQYSPTSEVGKITKS
TH_0355|M.thermoresistible__bu -DALSIGGNHLIHALRRNMNITILLFNNRIYGLTKGQYSPTSEVGKITKS
MAB_1595|M.abscessus_ATCC_1997 -DALSIGGNHLIHTLRRNVNLTILLFNNRIYGLTKGQYSPTSETGKVTKS
Mvan_4109|M.vanbaalenii_PYR-1 VDFGTVRGTQFLEPLFEFSGACAGCGETPYVKLLSQLFGDRLMVANATGC
MMAR_3408|M.marinum_M VDFGTVRGTQFLQPLFEFSGACAGCGETPYLKLLSQLFGDRLMVANATGC
* :: *.:::..: . . :. * . :. ..: * .
Mb2481c|M.bovis_AF2122/97 TPMGSLDHPFNPVSLALGAEATFVGRALDSDRNGLTEVLRAAAQHR----
Rv2454c|M.tuberculosis_H37Rv TPMGSLDHPFNPVSLALGAEATFVGRALDSDRNGLTEVLRAAAQHR----
MUL_3725|M.ulcerans_Agy99 TPMGSLDTPFNPVSLALGAEATFVGRALDSDRAGLSEVLRAATEHR----
MAV_1718|M.avium_104 TPMGSLDHPFNPVSLALGAEATFVGRALDSDRAGLTEVLQAAAGHR----
Mflv_2617|M.gilvum_PYR-GCK TPMGSLDYPFNPVSLALGAEATFVGRALDSDRKGLTEVLRGAAEHR----
MSMEG_4645|M.smegmatis_MC2_155 TPMGSLDYPFNPVSLALGAEATFVGRALDSDRKGLSEVLRGAAEHR----
TH_0355|M.thermoresistible__bu TPMGSLDHPFNPVSLALGAEATFVGRALDSDRKGLTEVLRGAAQHR----
MAB_1595|M.abscessus_ATCC_1997 TPMGSLDYPFNPVSLALGAEATFVGRALDSDKKGLSEVLRAAAAHR----
Mvan_4109|M.vanbaalenii_PYR-1 SSIYGGSLPTTPWTTNAEGRGPAWSNSLFEDNAEFGLGMRLAGDAHVRLA
MMAR_3408|M.marinum_M SSIYGGNLPTTPWATNAEGRGPAWSNSLFEDNAEFGLGMRLAADTHVRQA
:.: . . * .* : .... ..:* .*. : :: * :
Mb2481c|M.bovis_AF2122/97 -----------GAALVEILQDCPIFNDGSFDALRKEGAEER---------
Rv2454c|M.tuberculosis_H37Rv -----------GAALVEILQDCPIFNDGSFDALRKEGAEER---------
MUL_3725|M.ulcerans_Agy99 -----------GAALVEILQDCPIFNDGSFDALRKEGSEER---------
MAV_1718|M.avium_104 -----------GAAVVEILQDCPIFNDGSFDVLRKEGAEER---------
Mflv_2617|M.gilvum_PYR-GCK -----------GAALVEIMQDCPIFNDGSFDALRKEGAEER---------
MSMEG_4645|M.smegmatis_MC2_155 -----------GAALVEIMQDCPIFNDGSFDALRKEGAEER---------
TH_0355|M.thermoresistible__bu -----------GAALVEIMQDCPIFNDGSFDALRKEGSEER---------
MAB_1595|M.abscessus_ATCC_1997 -----------GAALVEILQDCPIFNDGSFDLLRKEGAEQR---------
Mvan_4109|M.vanbaalenii_PYR-1 RRRLTELRDTLGGAFVDAILDAPQRRESELAAQRERVAELRDRLACLD--
MMAR_3408|M.marinum_M RHRLTELRDVLGADLVDAILAAPQERESELRAQRERVAELRARLDELDGL
*. .*: : .* .:..: *:. :* *
Mb2481c|M.bovis_AF2122/97 -----------VIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDE
Rv2454c|M.tuberculosis_H37Rv -----------VIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDE
MUL_3725|M.ulcerans_Agy99 -----------VINVHHGEPIVFGANGEYCVVRSGFGLDVAKIADVAVDE
MAV_1718|M.avium_104 -----------VISVRHGEPIVFGANGEYCVVQSGFGLEVAKTADVSVDE
Mflv_2617|M.gilvum_PYR-GCK -----------LINLAHGEPITFGADGEYCVVKSGYGLEVAKTADVSAEE
MSMEG_4645|M.smegmatis_MC2_155 -----------LINLTHGEPITFGADGEYAVVKSGYGLEIAKTAEVSADD
TH_0355|M.thermoresistible__bu -----------LINLKHGEPIVFGANGEYCVIQSGYGLEVAKTADVSAEQ
MAB_1595|M.abscessus_ATCC_1997 -----------VINVRHGEPITFGAEGELCVIRSGFGLEVAKTADVKVED
Mvan_4109|M.vanbaalenii_PYR-1 -AAVTTDLLSVVDHLVRRSVWIVGGDGWAYDIGSG-GLDHVLATGHNVNV
MMAR_3408|M.marinum_M APAQADELRSVIDHLIRRSVWIVGGDGWAYDIGAG-GLDHVLASGHNVNV
: : : . .*.:* : :* **: . : :
Mb2481c|M.bovis_AF2122/97 IIVHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVV
Rv2454c|M.tuberculosis_H37Rv IIVHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVV
MUL_3725|M.ulcerans_Agy99 IVVHDAHADDAAYAFALSRLSDQNLEHTVVGIFRSISRPAYDDAARSQIS
MAV_1718|M.avium_104 IVVHDAHTDNSAYAFALSRLSDQNLEHTVLGIFRDISRPTYDDAARAQVQ
Mflv_2617|M.gilvum_PYR-GCK IVVHDATLQDPAYAFALSRLSEQNLDHMVMGIFRRVNKPTYDDAAREQIA
MSMEG_4645|M.smegmatis_MC2_155 IVVHDAQIDDPAYAFALSRLSEQNLDHMVMGIFRKVSRPTYDDAARQQVA
TH_0355|M.thermoresistible__bu IVVHDAQIDDPAYAFALSRLSEQNLEHMVMGIFRQVSRPTYDDAARAQIA
MAB_1595|M.abscessus_ATCC_1997 IVVHDAHSDDPAYAFALSRLSEQDLEHTVMGVFRSVQRPTYDDLAREQLT
Mvan_4109|M.vanbaalenii_PYR-1 LVLDTEVYSNTGGQMSKATPLGAVAKFAAAGKTVPLKDLALQAIAYGNVY
MMAR_3408|M.marinum_M LVLDTEVYSNTGGQMSKSTPLGAVAKFAAGGKTVPRKDLALQAISYGNVY
:::. .:.. :: : .. . * . : : : ::
Mb2481c|M.bovis_AF2122/97 AARNAAPSGTAALQSLLHGRDTWTVD------------------------
Rv2454c|M.tuberculosis_H37Rv AARNAAPSGTAALQSLLHGRDTWTVD------------------------
MUL_3725|M.ulcerans_Agy99 AARESTPSDSAALQSLLRGRDTWTVS------------------------
MAV_1718|M.avium_104 AAQSAKAFDSAALQSLLRGRDTWTVD------------------------
Mflv_2617|M.gilvum_PYR-GCK SARSSRAHDTAALQSLLRGKDTWTVD------------------------
MSMEG_4645|M.smegmatis_MC2_155 TAIESRPHDTAALQSLLRGKDTWTVD------------------------
TH_0355|M.thermoresistible__bu AARADKAHDTQALQALLRGKDTWTVD------------------------
MAB_1595|M.abscessus_ATCC_1997 AAAAAKPSDTAALQALLTGRDTWTVS------------------------
Mvan_4109|M.vanbaalenii_PYR-1 VARVAMGADPQQTLQAFREAEAYDGPSLVIAYSQCIAHGIDMRLGMDQQY
MMAR_3408|M.marinum_M VARVAMGADPQQTLLAFREAEAYDGPSLVIAYSHCIAHGFELRYGLDQQY
* .. : :::
Mb2481c|M.bovis_AF2122/97 --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3725|M.ulcerans_Agy99 --------------------------------------------------
MAV_1718|M.avium_104 --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------------------------
TH_0355|M.thermoresistible__bu --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 RAVASGHWPLLRFDPVMRAAGKNPFLLDSHRPRIALEHYRDRELRYRSLS
MMAR_3408|M.marinum_M RAVASGHWPLIRYNPVLRSTGRPPFLLDSHRPRLALADYRDRELRFRSLA
Mb2481c|M.bovis_AF2122/97 ------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv ------------------------------------------------
MUL_3725|M.ulcerans_Agy99 ------------------------------------------------
MAV_1718|M.avium_104 ------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK ------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155 ------------------------------------------------
TH_0355|M.thermoresistible__bu ------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997 ------------------------------------------------
Mvan_4109|M.vanbaalenii_PYR-1 NADPVEAERLLGLAEQAIEQRWNVYEAMASQQRSTKREHLRPDARREP
MMAR_3408|M.marinum_M NSDPDEADRLLALAEESIDQRWEVYEDMASRAP----QEFPSDSRRES