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M. marinum M MMAR_3408 (-)

annotation: pyruvate ferredoxin/flavodoxin oxidoreductase family protein
coordinates: 4202608 - 4206189
length: 1193

MTRTTVDGNEATASVAYRLNEVCCIYPITPSSPMAELADAWSNQNRPNIYGTVPTVVEMQSEGGAAGALH
GSLQGGALTTTFTASQGLLLMIPNMYKIAGELTSAVMHVAARSIAAQALSIFGDHQDVMAVRQTGFALLA
SASVQEAHDLALIAQAATLRTRVPFVHFFDGFRTSHELNTIEVLTDDDLRALVPQELVLAHRDRALSPDR
PSIRGTAQNPDTYFQARETVNPFYARVPEVVEGLLRELGERTGRPMHIVDYTGHPEAERVMVLMGSGGQT
AAETVTALTERGERVGVAQIRLYRPFPAEALLAALPPTVRAIAVLDRTKEPGSQGEPLYLDVTAALAEAY
SSGQRSSLPVVCGGRYGLSSKEFTPGMVAGVFAELAGQRPRTRFTVGIDDDVSGTSISYDPDFDIETPAT
TKAVFFGMGSDGTVGANKNTIKILGGEEDIYAQGYFVYDSKKSGSQTVSHLRFGPQPIRAPYLVQQASFV
GCHHQRFLNKVDVLGRAAHGAALLLNSARPPERVWDSLPAPVQQQIIDKRIRLYVVDAGKIAREVGLAGR
INIVLQTCFFAIADVLPVDQAIAKIKASVAKTYAAHGADVVAREVNAVDHALAGLHPVQVPDTVSSTRQL
EPPVPQHAPEFVRTVTAEMIAGRGDGLPVSALPADGSYPSGTAAYEKRNISDLVAVWDPDTCIQCGNCSF
VCPHSVIRTTLYPRDRLDAAPATFASAPLDAVGLPDTRYTLQVYAEDCTGCNLCVEACPAVVPGKPVTKA
INLAPREPLVAAARENIAFFETLPVANRSRVDFGTVRGTQFLQPLFEFSGACAGCGETPYLKLLSQLFGD
RLMVANATGCSSIYGGNLPTTPWATNAEGRGPAWSNSLFEDNAEFGLGMRLAADTHVRQARHRLTELRDV
LGADLVDAILAAPQERESELRAQRERVAELRARLDELDGLAPAQADELRSVIDHLIRRSVWIVGGDGWAY
DIGAGGLDHVLASGHNVNVLVLDTEVYSNTGGQMSKSTPLGAVAKFAAGGKTVPRKDLALQAISYGNVYV
ARVAMGADPQQTLLAFREAEAYDGPSLVIAYSHCIAHGFELRYGLDQQYRAVASGHWPLIRYNPVLRSTG
RPPFLLDSHRPRLALADYRDRELRFRSLANSDPDEADRLLALAEESIDQRWEVYEDMASRAPQEFPSDSR
RES
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3408--100% (1193)pyruvate ferredoxin/flavodoxin oxidoreductase family protein
M. marinum MMMAR_3802porB2e-0828.02% (182) pyruvate:ferredoxin oxidoreductase PorB, beta subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2481c-9e-0927.62% (181) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. gilvum PYR-GCKMflv_2617-2e-0928.42% (183) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. tuberculosis H37RvRv2454c-1e-0827.62% (181) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1595-1e-0831.69% (142) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. avium 104MAV_1718orB1e-0725.41% (181) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. smegmatis MC2 155MSMEG_4645orB2e-0826.71% (161) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. thermoresistible (build 8)TH_0355-8e-0825.00% (160) PROBABLE OXIDOREDUCTASE (BETA SUBUNIT)
M. ulcerans Agy99MUL_3725porB4e-0827.47% (182) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. vanbaalenii PYR-1Mvan_4109-0.077.05% (1194) pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing

CLUSTAL 2.0.9 multiple sequence alignment


Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               MTRTTVDGNEATASVAYRLNEVCCIYPITPSSPMAELADAWSNQNRPNIY
Mvan_4109|M.vanbaalenii_PYR-1       -MRVAVDGNEAAVSVAYRLNEVCCIYPITPSSPMAELADEWSAAERTNVW
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               GTVPTVVEMQSEGGAAGALHGSLQGGALTTTFTASQGLLLMIPNMYKIAG
Mvan_4109|M.vanbaalenii_PYR-1       GAVPTVVEMQSEGGAAGALHGALQSGALTTTYTSSQGLLLMIPNMYKIAG
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               ELTSAVMHVAARSIAAQALSIFGDHQDVMAVRQTGFALLASASVQEAHDL
Mvan_4109|M.vanbaalenii_PYR-1       ELTSAVIHVAARSIAAQGLSIFGDHSDVMAVRQTGFALLGSASVQEAHDL
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               ALIAQAATLRTRVPFVHFFDGFRTSHELNTIEVLTDDDLRALVPQELVLA
Mvan_4109|M.vanbaalenii_PYR-1       ALVAQAATLATRVPFVHFFDGFRTSHEINTIETLSDDDLRSLVPEELIWA
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               HRDRALSPDRPSIRGTAQNPDTYFQARETVNPFYARVPEVVEGLLRELGE
Mvan_4109|M.vanbaalenii_PYR-1       HRERALSPERPFIRGTAQNPDVYFQARETVNPFYARVPGVVEDLMARLGE
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               RTGRPMHIVDYTGHPEAERVMVLMGSGGQTAAETVTALTERGERVGVAQI
Mvan_4109|M.vanbaalenii_PYR-1       RTGRAMHIVDYSGHPEAERVLVLMGSGAETVQQTVAALVDRGERVGVVQV
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               RLYRPFPAEALLAALPPTVRAIAVLDRTKEPGSQGEPLYLDVTAALAEAY
Mvan_4109|M.vanbaalenii_PYR-1       RLYRPFPTAAFLESLPATVRAVGVLDRTKEPGSIGEPLYLDVVAALAGAC
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               SSGQRSSLPVVCGGRYGLSSKEFTPGMVAGVFAELAGQRPRTRFTVGIDD
Mvan_4109|M.vanbaalenii_PYR-1       ADGDRAAMPRVTGGRYGLSSKEFTPAMVAGVLTELASERSRRQFTVGIDD
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               DVSGTSISYDPDFDIETPATTKAVFFGMGSDGTVGANKNTIKILGGEEDI
Mvan_4109|M.vanbaalenii_PYR-1       DVSRTSVEYDPSFDIESPETVRAVFFGLGSDGTVSANKNTIKILGSEPGL
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               YAQGYFVYDSKKSGSQTVSHLRFGPQPIRAPYLVQQASFVGCHHQRFLNK
Mvan_4109|M.vanbaalenii_PYR-1       HAQAYFVYDSKKSGSQTESHLRFGPHPIRAPYLVTAANFIGCHQFRFLDK
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               VDVLGRAAHGAALLLNSARPPERVWDSLPAPVQQQIIDKRIRLYVVDAGK
Mvan_4109|M.vanbaalenii_PYR-1       VDVLGRAAPGATLLLNCRLPAERIWDALPRRVQEQILDKKITLYVVDADR
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               IAREVGLAGRINIVLQTCFFAIADVLPVDQAIAKIKASVAKTYAAHGADV
Mvan_4109|M.vanbaalenii_PYR-1       IARAAGLPGRINIVLQTCFFAISEVLPRDRAIDRIKDSVRKTYGNRGPDV
                                                                                      

Mb2481c|M.bovis_AF2122/97           --------------------------------MTRSGDEAQLMTGVTGDL
Rv2454c|M.tuberculosis_H37Rv        --------------------------------MTRSGDEAQLMTGVTGDL
MUL_3725|M.ulcerans_Agy99           ------------------------------------------MTSVIGNL
MAV_1718|M.avium_104                ------------------------------------------MTDVVGNL
Mflv_2617|M.gilvum_PYR-GCK          -----------------------------------MTTARSEADRASAQL
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      -------------------------------------------------V
MAB_1595|M.abscessus_ATCC_1997      -------------------------------------MTDLLNEASTANG
MMAR_3408|M.marinum_M               VAREVNAVDHALAGLHPVQVPDTVSSTRQLEPPVPQHAPEFVRTVTAEMI
Mvan_4109|M.vanbaalenii_PYR-1       LAAELAAVDGAVAGLQRIEVPTSATSIRVVPPPVPESAPEFVRTVTAEMM
                                                                                      

Mb2481c|M.bovis_AF2122/97           AGTELGLTPS-LTKNAGVPTTDQPQKGK---DFTSDQEVRWCPGCG--DY
Rv2454c|M.tuberculosis_H37Rv        AGTELGLTPS-LTKNAGVPTTDQPQKGK---DFTSDQEVRWCPGCG--DY
MUL_3725|M.ulcerans_Agy99           AGTNLGVTPV-LSKNTGVPTTDQPQKGK---DFTSDQEVRWCPGCG--DY
MAV_1718|M.avium_104                AGKDLGLTAK-LTKNDGVPTTDQPQKAK---DFTSDQEVRWCPGCG--DY
Mflv_2617|M.gilvum_PYR-GCK          VGNDLGLTPGGLTKTSLVPKTDAPQKGK---DFTSDQEVRWCPGCG--DY
MSMEG_4645|M.smegmatis_MC2_155      --------------MSLVPTADQPQKAK---DFTSDQEVRWCPGCG--DY
TH_0355|M.thermoresistible__bu      IGADLGLIPAGLPKTAGVPTTDQPQKGK---DFTSDQEVRWCPGCG--DY
MAB_1595|M.abscessus_ATCC_1997      TGSLNGLELG-LTANALVPTTDEEQKAK---DFTSDQEVRWCPGCG--DY
MMAR_3408|M.marinum_M               AGRGDGLPVSALPADGSYPSGTAAYEKRNISDLVAVWDPDTCIQCGNCSF
Mvan_4109|M.vanbaalenii_PYR-1       AGRGNALPVSALPVDGTYPSGTTAYEKRNISELVAVWDPDTCIQCGNCGF
                                                      *.     : :   ::.:  :   *  **  .:

Mb2481c|M.bovis_AF2122/97           VILNTIRN--FLPELGLRRENIVFISGIGCSSRFP--------YYLETYG
Rv2454c|M.tuberculosis_H37Rv        VILNTIRN--FLPELGLRRENIVFISGIGCSSRFP--------YYLETYG
MUL_3725|M.ulcerans_Agy99           VILNTIRN--FLPELGLRRENIVFISGIGCSSRFP--------YYLETYG
MAV_1718|M.avium_104                VILNTIRN--FLPDLGLRRENIVFISGIGCSSRFP--------YYLETYG
Mflv_2617|M.gilvum_PYR-GCK          VILNTIRN--FLPELGLRRENIAFVSGIGCSSRFP--------YYLETYG
MSMEG_4645|M.smegmatis_MC2_155      VILNTIRN--FLPELGLRRENIAFVSGIGCSSRFP--------YYLETYG
TH_0355|M.thermoresistible__bu      VILNTIRN--FLPELGLRRENIAFISGIGCSSRFP--------YYLETYG
MAB_1595|M.abscessus_ATCC_1997      VILNTIRG--FLPELGLKRENIVFISGIGCSSRFP--------YYLDTYG
MMAR_3408|M.marinum_M               VCPHSVIRTTLYPRDRLDAAPATFASAPLDAVGLPDTRYTLQVYAEDCTG
Mvan_4109|M.vanbaalenii_PYR-1       VCPHSVIRSKFYDGSQLAGAPADFDSAPLDAVGLPGARFSLQVYTEDCTG
                                    *  :::    :     *      * *.   :  :*        *  :  *

Mb2481c|M.bovis_AF2122/97           FHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
Rv2454c|M.tuberculosis_H37Rv        FHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
MUL_3725|M.ulcerans_Agy99           FHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
MAV_1718|M.avium_104                FHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
Mflv_2617|M.gilvum_PYR-GCK          FHSIHGRAPTIATG---------------LALAREDLSVWVVTGDG----
MSMEG_4645|M.smegmatis_MC2_155      FHSIHGRAPTIATG---------------LALARPDLSVWVVTGDG----
TH_0355|M.thermoresistible__bu      FHSIHGRAPTIATG---------------LALARPDLSVWVVTGDG----
MAB_1595|M.abscessus_ATCC_1997      MHSIHGRAPAIATG---------------LALAREDLSVWVVTGDG----
MMAR_3408|M.marinum_M               CNLCVEACPAVVPGKPVTKAINLAPREPLVAAARENIAFFETLPVANRSR
Mvan_4109|M.vanbaalenii_PYR-1       CGLCVEACPVVIPGPTATKAINLGPAEPRMATERENVRFFESLPTNDRSR
                                           .*.: .*               :*  * :: .:          

Mb2481c|M.bovis_AF2122/97           -DALSIGGNHLIHALRRNINVTILLFNNRIYGLTKGQYSPTSEVGKVTKS
Rv2454c|M.tuberculosis_H37Rv        -DALSIGGNHLIHALRRNINVTILLFNNRIYGLTKGQYSPTSEVGKVTKS
MUL_3725|M.ulcerans_Agy99           -DALSIGGNHLIHAVRRNVNITILLFNNRIYGLTKGQYSPTSEVGKVTKS
MAV_1718|M.avium_104                -DALSIGGNHLIHALRRNVNITILLFNNRIYGLTKGQYSPTSEVGKITKS
Mflv_2617|M.gilvum_PYR-GCK          -DALSIGGNHLIHALRRNINITILLFNNRIYGLTKGQYSPTSETGKVTKS
MSMEG_4645|M.smegmatis_MC2_155      -DSLSIGGNHLIHALRRNINITILLFNNRIYGLTKGQYSPTSEVGKITKS
TH_0355|M.thermoresistible__bu      -DALSIGGNHLIHALRRNMNITILLFNNRIYGLTKGQYSPTSEVGKITKS
MAB_1595|M.abscessus_ATCC_1997      -DALSIGGNHLIHTLRRNVNLTILLFNNRIYGLTKGQYSPTSETGKVTKS
MMAR_3408|M.marinum_M               VDFGTVRGTQFLQPLFEFSGACAGCGETPYLKLLSQLFGDRLMVANATGC
Mvan_4109|M.vanbaalenii_PYR-1       VDFGTVRGTQFLEPLFEFSGACAGCGETPYVKLLSQLFGDRLMVANATGC
                                     *  :: *.:::..: .  .      :.    * .  :.    ..: * .

Mb2481c|M.bovis_AF2122/97           TPMGSLDHPFNPVSLALGAEATFVGRALDSDRNGLTEVLRAAAQHR----
Rv2454c|M.tuberculosis_H37Rv        TPMGSLDHPFNPVSLALGAEATFVGRALDSDRNGLTEVLRAAAQHR----
MUL_3725|M.ulcerans_Agy99           TPMGSLDTPFNPVSLALGAEATFVGRALDSDRAGLSEVLRAATEHR----
MAV_1718|M.avium_104                TPMGSLDHPFNPVSLALGAEATFVGRALDSDRAGLTEVLQAAAGHR----
Mflv_2617|M.gilvum_PYR-GCK          TPMGSLDYPFNPVSLALGAEATFVGRALDSDRKGLTEVLRGAAEHR----
MSMEG_4645|M.smegmatis_MC2_155      TPMGSLDYPFNPVSLALGAEATFVGRALDSDRKGLSEVLRGAAEHR----
TH_0355|M.thermoresistible__bu      TPMGSLDHPFNPVSLALGAEATFVGRALDSDRKGLTEVLRGAAQHR----
MAB_1595|M.abscessus_ATCC_1997      TPMGSLDYPFNPVSLALGAEATFVGRALDSDKKGLSEVLRAAAAHR----
MMAR_3408|M.marinum_M               SSIYGGNLPTTPWATNAEGRGPAWSNSLFEDNAEFGLGMRLAADTHVRQA
Mvan_4109|M.vanbaalenii_PYR-1       SSIYGGSLPTTPWTTNAEGRGPAWSNSLFEDNAEFGLGMRLAGDAHVRLA
                                    :.: . . * .* :    ....  ..:* .*.  :   :: *   :    

Mb2481c|M.bovis_AF2122/97           -----------GAALVEILQDCPIFNDGSFDALRKEGAEER---------
Rv2454c|M.tuberculosis_H37Rv        -----------GAALVEILQDCPIFNDGSFDALRKEGAEER---------
MUL_3725|M.ulcerans_Agy99           -----------GAALVEILQDCPIFNDGSFDALRKEGSEER---------
MAV_1718|M.avium_104                -----------GAAVVEILQDCPIFNDGSFDVLRKEGAEER---------
Mflv_2617|M.gilvum_PYR-GCK          -----------GAALVEIMQDCPIFNDGSFDALRKEGAEER---------
MSMEG_4645|M.smegmatis_MC2_155      -----------GAALVEIMQDCPIFNDGSFDALRKEGAEER---------
TH_0355|M.thermoresistible__bu      -----------GAALVEIMQDCPIFNDGSFDALRKEGSEER---------
MAB_1595|M.abscessus_ATCC_1997      -----------GAALVEILQDCPIFNDGSFDLLRKEGAEQR---------
MMAR_3408|M.marinum_M               RHRLTELRDVLGADLVDAILAAPQERESELRAQRERVAELRARLDELDGL
Mvan_4109|M.vanbaalenii_PYR-1       RRRLTELRDTLGGAFVDAILDAPQRRESELAAQRERVAELRDRLACLD--
                                               *. .*: :  .*  .:..:   *:. :* *         

Mb2481c|M.bovis_AF2122/97           -----------VIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDE
Rv2454c|M.tuberculosis_H37Rv        -----------VIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDE
MUL_3725|M.ulcerans_Agy99           -----------VINVHHGEPIVFGANGEYCVVRSGFGLDVAKIADVAVDE
MAV_1718|M.avium_104                -----------VISVRHGEPIVFGANGEYCVVQSGFGLEVAKTADVSVDE
Mflv_2617|M.gilvum_PYR-GCK          -----------LINLAHGEPITFGADGEYCVVKSGYGLEVAKTADVSAEE
MSMEG_4645|M.smegmatis_MC2_155      -----------LINLTHGEPITFGADGEYAVVKSGYGLEIAKTAEVSADD
TH_0355|M.thermoresistible__bu      -----------LINLKHGEPIVFGANGEYCVIQSGYGLEVAKTADVSAEQ
MAB_1595|M.abscessus_ATCC_1997      -----------VINVRHGEPITFGAEGELCVIRSGFGLEVAKTADVKVED
MMAR_3408|M.marinum_M               APAQADELRSVIDHLIRRSVWIVGGDGWAYDIGAG-GLDHVLASGHNVNV
Mvan_4109|M.vanbaalenii_PYR-1       -AAVTTDLLSVVDHLVRRSVWIVGGDGWAYDIGSG-GLDHVLATGHNVNV
                                               :  : : .   .*.:*    : :* **: .  :    : 

Mb2481c|M.bovis_AF2122/97           IIVHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVV
Rv2454c|M.tuberculosis_H37Rv        IIVHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVV
MUL_3725|M.ulcerans_Agy99           IVVHDAHADDAAYAFALSRLSDQNLEHTVVGIFRSISRPAYDDAARSQIS
MAV_1718|M.avium_104                IVVHDAHTDNSAYAFALSRLSDQNLEHTVLGIFRDISRPTYDDAARAQVQ
Mflv_2617|M.gilvum_PYR-GCK          IVVHDATLQDPAYAFALSRLSEQNLDHMVMGIFRRVNKPTYDDAAREQIA
MSMEG_4645|M.smegmatis_MC2_155      IVVHDAQIDDPAYAFALSRLSEQNLDHMVMGIFRKVSRPTYDDAARQQVA
TH_0355|M.thermoresistible__bu      IVVHDAQIDDPAYAFALSRLSEQNLEHMVMGIFRQVSRPTYDDAARAQIA
MAB_1595|M.abscessus_ATCC_1997      IVVHDAHSDDPAYAFALSRLSEQDLEHTVMGVFRSVQRPTYDDLAREQLT
MMAR_3408|M.marinum_M               LVLDTEVYSNTGGQMSKSTPLGAVAKFAAGGKTVPRKDLALQAISYGNVY
Mvan_4109|M.vanbaalenii_PYR-1       LVLDTEVYSNTGGQMSKATPLGAVAKFAAAGKTVPLKDLALQAIAYGNVY
                                    :::.    .:..  :: :       .. . *     .  : :  :  :: 

Mb2481c|M.bovis_AF2122/97           AARNAAPSGTAALQSLLHGRDTWTVD------------------------
Rv2454c|M.tuberculosis_H37Rv        AARNAAPSGTAALQSLLHGRDTWTVD------------------------
MUL_3725|M.ulcerans_Agy99           AARESTPSDSAALQSLLRGRDTWTVS------------------------
MAV_1718|M.avium_104                AAQSAKAFDSAALQSLLRGRDTWTVD------------------------
Mflv_2617|M.gilvum_PYR-GCK          SARSSRAHDTAALQSLLRGKDTWTVD------------------------
MSMEG_4645|M.smegmatis_MC2_155      TAIESRPHDTAALQSLLRGKDTWTVD------------------------
TH_0355|M.thermoresistible__bu      AARADKAHDTQALQALLRGKDTWTVD------------------------
MAB_1595|M.abscessus_ATCC_1997      AAAAAKPSDTAALQALLTGRDTWTVS------------------------
MMAR_3408|M.marinum_M               VARVAMGADPQQTLLAFREAEAYDGPSLVIAYSHCIAHGFELRYGLDQQY
Mvan_4109|M.vanbaalenii_PYR-1       VARVAMGADPQQTLQAFREAEAYDGPSLVIAYSQCIAHGIDMRLGMDQQY
                                     *      ..      :   :::                           

Mb2481c|M.bovis_AF2122/97           --------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3725|M.ulcerans_Agy99           --------------------------------------------------
MAV_1718|M.avium_104                --------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------------------------
TH_0355|M.thermoresistible__bu      --------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3408|M.marinum_M               RAVASGHWPLIRYNPVLRSTGRPPFLLDSHRPRLALADYRDRELRFRSLA
Mvan_4109|M.vanbaalenii_PYR-1       RAVASGHWPLLRFDPVMRAAGKNPFLLDSHRPRIALEHYRDRELRYRSLS
                                                                                      

Mb2481c|M.bovis_AF2122/97           ------------------------------------------------
Rv2454c|M.tuberculosis_H37Rv        ------------------------------------------------
MUL_3725|M.ulcerans_Agy99           ------------------------------------------------
MAV_1718|M.avium_104                ------------------------------------------------
Mflv_2617|M.gilvum_PYR-GCK          ------------------------------------------------
MSMEG_4645|M.smegmatis_MC2_155      ------------------------------------------------
TH_0355|M.thermoresistible__bu      ------------------------------------------------
MAB_1595|M.abscessus_ATCC_1997      ------------------------------------------------
MMAR_3408|M.marinum_M               NSDPDEADRLLALAEESIDQRWEVYEDMASRAP----QEFPSDSRRES
Mvan_4109|M.vanbaalenii_PYR-1       NADPVEAERLLGLAEQAIEQRWNVYEAMASQQRSTKREHLRPDARREP