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TDLIGSDLGLTPAGLTKTSLVPTTDEPQKAKDFTTDQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAF VSGIGCSSRFPYYLETYGFHSIHGRAPTIATGLALARPDLSVWVVTGDGDALSIGGNHLIHALRRNINVT ILLFNNRIYGLTKGQYSPTSETGKVTKSTPMGSLDYPFNPVSLALGAEATFVGRALDSDRKGLSEVLRGA AQHRGAALVEIMQDCPIFNDGSFDALRKEGAEERLINVTHGEPITFGADGEYCVVKSGYGLEVAKTADVP ADEIVVHDATLQDPAYAFALSRLSEQNLDHMVMGIFRQVSKPTYDDAARQQLATAREAKAHDTAALQSLL RGKDTWTVD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3964 | - | - | 100% (360) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. vanbaalenii PYR-1 | Mvan_4109 | - | 7e-10 | 28.57% (161) | pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2481c | - | 0.0 | 86.03% (358) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. gilvum PYR-GCK | Mflv_2617 | - | 0.0 | 93.56% (357) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. tuberculosis H37Rv | Rv2454c | - | 0.0 | 86.03% (358) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1595 | - | 1e-173 | 81.25% (368) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. marinum M | MMAR_3802 | porB | 1e-176 | 83.19% (357) | pyruvate:ferredoxin oxidoreductase PorB, beta subunit |
| M. avium 104 | MAV_1718 | orB | 1e-177 | 83.80% (358) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. smegmatis MC2 155 | MSMEG_4645 | orB | 0.0 | 92.96% (341) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
| M. thermoresistible (build 8) | TH_0355 | - | 0.0 | 89.36% (357) | PROBABLE OXIDOREDUCTASE (BETA SUBUNIT) |
| M. ulcerans Agy99 | MUL_3725 | porB | 1e-175 | 82.91% (357) | 2-oxoglutarate ferredoxin oxidoreductase subunit beta |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3964|M.vanbaalenii_PYR-1 --------------MTDLIGSDLGLTPAGLTKTSLVPTTDEPQKAKDFTT
Mflv_2617|M.gilvum_PYR-GCK ---MTTARSEADRASAQLVGNDLGLTPGGLTKTSLVPKTDAPQKGKDFTS
MSMEG_4645|M.smegmatis_MC2_155 --------------------------------MSLVPTADQPQKAKDFTS
TH_0355|M.thermoresistible__bu -----------------VIGADLGLIPAGLPKTAGVPTTDQPQKGKDFTS
Mb2481c|M.bovis_AF2122/97 MTRSGDEAQLMTGVTGDLAGTELGLTPS-LTKNAGVPTTDQPQKGKDFTS
Rv2454c|M.tuberculosis_H37Rv MTRSGDEAQLMTGVTGDLAGTELGLTPS-LTKNAGVPTTDQPQKGKDFTS
MAV_1718|M.avium_104 ----------MTDVVGNLAGKDLGLTAK-LTKNDGVPTTDQPQKAKDFTS
MMAR_3802|M.marinum_M ----------MTSVIGNLAGTNLGVTPV-FSKNTGVPTTDQPQKGKDFTS
MUL_3725|M.ulcerans_Agy99 ----------MTSVIGNLAGTNLGVTPV-LSKNTGVPTTDQPQKGKDFTS
MAB_1595|M.abscessus_ATCC_1997 -----MTDLLNEASTANGTGSLNGLELG-LTANALVPTTDEEQKAKDFTS
**.:* **.****:
Mvan_3964|M.vanbaalenii_PYR-1 DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAFVSGIGCSSRFPYYLE
Mflv_2617|M.gilvum_PYR-GCK DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAFVSGIGCSSRFPYYLE
MSMEG_4645|M.smegmatis_MC2_155 DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAFVSGIGCSSRFPYYLE
TH_0355|M.thermoresistible__bu DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAFISGIGCSSRFPYYLE
Mb2481c|M.bovis_AF2122/97 DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLE
Rv2454c|M.tuberculosis_H37Rv DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLE
MAV_1718|M.avium_104 DQEVRWCPGCGDYVILNTIRNFLPDLGLRRENIVFISGIGCSSRFPYYLE
MMAR_3802|M.marinum_M DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLE
MUL_3725|M.ulcerans_Agy99 DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLE
MAB_1595|M.abscessus_ATCC_1997 DQEVRWCPGCGDYVILNTIRGFLPELGLKRENIVFISGIGCSSRFPYYLD
********************.***:***:****.*:*************:
Mvan_3964|M.vanbaalenii_PYR-1 TYGFHSIHGRAPTIATGLALARPDLSVWVVTGDGDALSIGGNHLIHALRR
Mflv_2617|M.gilvum_PYR-GCK TYGFHSIHGRAPTIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
MSMEG_4645|M.smegmatis_MC2_155 TYGFHSIHGRAPTIATGLALARPDLSVWVVTGDGDSLSIGGNHLIHALRR
TH_0355|M.thermoresistible__bu TYGFHSIHGRAPTIATGLALARPDLSVWVVTGDGDALSIGGNHLIHALRR
Mb2481c|M.bovis_AF2122/97 TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
Rv2454c|M.tuberculosis_H37Rv TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
MAV_1718|M.avium_104 TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
MMAR_3802|M.marinum_M TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
MUL_3725|M.ulcerans_Agy99 TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHAVRR
MAB_1595|M.abscessus_ATCC_1997 TYGMHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHTLRR
***:********:********* ************:**********::**
Mvan_3964|M.vanbaalenii_PYR-1 NINVTILLFNNRIYGLTKGQYSPTSETGKVTKSTPMGSLDYPFNPVSLAL
Mflv_2617|M.gilvum_PYR-GCK NINITILLFNNRIYGLTKGQYSPTSETGKVTKSTPMGSLDYPFNPVSLAL
MSMEG_4645|M.smegmatis_MC2_155 NINITILLFNNRIYGLTKGQYSPTSEVGKITKSTPMGSLDYPFNPVSLAL
TH_0355|M.thermoresistible__bu NMNITILLFNNRIYGLTKGQYSPTSEVGKITKSTPMGSLDHPFNPVSLAL
Mb2481c|M.bovis_AF2122/97 NINVTILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDHPFNPVSLAL
Rv2454c|M.tuberculosis_H37Rv NINVTILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDHPFNPVSLAL
MAV_1718|M.avium_104 NVNITILLFNNRIYGLTKGQYSPTSEVGKITKSTPMGSLDHPFNPVSLAL
MMAR_3802|M.marinum_M NVNITILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDTPFNPVSLAL
MUL_3725|M.ulcerans_Agy99 NVNITILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDTPFNPVSLAL
MAB_1595|M.abscessus_ATCC_1997 NVNLTILLFNNRIYGLTKGQYSPTSETGKVTKSTPMGSLDYPFNPVSLAL
*:*:**********************.**:********** *********
Mvan_3964|M.vanbaalenii_PYR-1 GAEATFVGRALDSDRKGLSEVLRGAAQHRGAALVEIMQDCPIFNDGSFDA
Mflv_2617|M.gilvum_PYR-GCK GAEATFVGRALDSDRKGLTEVLRGAAEHRGAALVEIMQDCPIFNDGSFDA
MSMEG_4645|M.smegmatis_MC2_155 GAEATFVGRALDSDRKGLSEVLRGAAEHRGAALVEIMQDCPIFNDGSFDA
TH_0355|M.thermoresistible__bu GAEATFVGRALDSDRKGLTEVLRGAAQHRGAALVEIMQDCPIFNDGSFDA
Mb2481c|M.bovis_AF2122/97 GAEATFVGRALDSDRNGLTEVLRAAAQHRGAALVEILQDCPIFNDGSFDA
Rv2454c|M.tuberculosis_H37Rv GAEATFVGRALDSDRNGLTEVLRAAAQHRGAALVEILQDCPIFNDGSFDA
MAV_1718|M.avium_104 GAEATFVGRALDSDRAGLTEVLQAAAGHRGAAVVEILQDCPIFNDGSFDV
MMAR_3802|M.marinum_M GAEATFVGRALDSDRAGLSEVLRAATEHRGAALVEILQDCPIFNDGSFDA
MUL_3725|M.ulcerans_Agy99 GAEATFVGRALDSDRAGLSEVLRAATEHRGAALVEILQDCPIFNDGSFDA
MAB_1595|M.abscessus_ATCC_1997 GAEATFVGRALDSDKKGLSEVLRAAAAHRGAALVEILQDCPIFNDGSFDL
**************: **:***:.*: *****:***:************
Mvan_3964|M.vanbaalenii_PYR-1 LRKEGAEERLINVTHGEPITFGADGEYCVVKSGYGLEVAKTADVPADEIV
Mflv_2617|M.gilvum_PYR-GCK LRKEGAEERLINLAHGEPITFGADGEYCVVKSGYGLEVAKTADVSAEEIV
MSMEG_4645|M.smegmatis_MC2_155 LRKEGAEERLINLTHGEPITFGADGEYAVVKSGYGLEIAKTAEVSADDIV
TH_0355|M.thermoresistible__bu LRKEGSEERLINLKHGEPIVFGANGEYCVIQSGYGLEVAKTADVSAEQIV
Mb2481c|M.bovis_AF2122/97 LRKEGAEERVIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDEII
Rv2454c|M.tuberculosis_H37Rv LRKEGAEERVIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDEII
MAV_1718|M.avium_104 LRKEGAEERVISVRHGEPIVFGANGEYCVVQSGFGLEVAKTADVSVDEIV
MMAR_3802|M.marinum_M LRKEGSEERVINVHHGEPIVFGANGEYCVVRSGFGLDVAKTADVAVDEIV
MUL_3725|M.ulcerans_Agy99 LRKEGSEERVINVHHGEPIVFGANGEYCVVRSGFGLDVAKIADVAVDEIV
MAB_1595|M.abscessus_ATCC_1997 LRKEGAEQRVINVRHGEPITFGAEGELCVIRSGFGLEVAKTADVKVEDIV
*****:*:*:*.: *****.***:** .*::**:**::** *:* ::*:
Mvan_3964|M.vanbaalenii_PYR-1 VHDATLQDPAYAFALSRLSEQNLDHMVMGIFRQVSKPTYDDAARQQLATA
Mflv_2617|M.gilvum_PYR-GCK VHDATLQDPAYAFALSRLSEQNLDHMVMGIFRRVNKPTYDDAAREQIASA
MSMEG_4645|M.smegmatis_MC2_155 VHDAQIDDPAYAFALSRLSEQNLDHMVMGIFRKVSRPTYDDAARQQVATA
TH_0355|M.thermoresistible__bu VHDAQIDDPAYAFALSRLSEQNLEHMVMGIFRQVSRPTYDDAARAQIAAA
Mb2481c|M.bovis_AF2122/97 VHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVVAA
Rv2454c|M.tuberculosis_H37Rv VHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVVAA
MAV_1718|M.avium_104 VHDAHTDNSAYAFALSRLSDQNLEHTVLGIFRDISRPTYDDAARAQVQAA
MMAR_3802|M.marinum_M VHDAHADDAAYAFALSRLSDQNLEHTVLGIFRSISRPAYDDAARSQISAA
MUL_3725|M.ulcerans_Agy99 VHDAHADDAAYAFALSRLSDQNLEHTVVGIFRSISRPAYDDAARSQISAA
MAB_1595|M.abscessus_ATCC_1997 VHDAHSDDPAYAFALSRLSEQDLEHTVMGVFRSVQRPTYDDLAREQLTAA
**** ::.**********:*:*:* *:*:** :.:*:*** ** *: :*
Mvan_3964|M.vanbaalenii_PYR-1 REAKAHDTAALQSLLRGKDTWTVD
Mflv_2617|M.gilvum_PYR-GCK RSSRAHDTAALQSLLRGKDTWTVD
MSMEG_4645|M.smegmatis_MC2_155 IESRPHDTAALQSLLRGKDTWTVD
TH_0355|M.thermoresistible__bu RADKAHDTQALQALLRGKDTWTVD
Mb2481c|M.bovis_AF2122/97 RNAAPSGTAALQSLLHGRDTWTVD
Rv2454c|M.tuberculosis_H37Rv RNAAPSGTAALQSLLHGRDTWTVD
MAV_1718|M.avium_104 QSAKAFDSAALQSLLRGRDTWTVD
MMAR_3802|M.marinum_M RESTPSDSAALQSLLRGRDTWTVS
MUL_3725|M.ulcerans_Agy99 RESTPSDSAALQSLLRGRDTWTVS
MAB_1595|M.abscessus_ATCC_1997 AAAKPSDTAALQALLTGRDTWTVS
. .: ***:** *:*****.