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M. tuberculosis H37Rv Rv2454c (-)

annotation: 2-oxoglutarate ferredoxin oxidoreductase subunit beta
coordinates: 2753625 - 2754746
length: 373

TRSGDEAQLMTGVTGDLAGTELGLTPSLTKNAGVPTTDQPQKGKDFTSDQEVRWCPGCGDYVILNTIRNF
LPELGLRRENIVFISGIGCSSRFPYYLETYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGN
HLIHALRRNINVTILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDHPFNPVSLALGAEATFVGRALD
SDRNGLTEVLRAAAQHRGAALVEILQDCPIFNDGSFDALRKEGAEERVIKVRHGEPIVFGANGEYCVVKS
GFGLEVAKTADVAIDEIIVHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVVAARN
AAPSGTAALQSLLHGRDTWTVD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2454c--100% (373)2-oxoglutarate ferredoxin oxidoreductase subunit beta

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2481c-0.0100.00% (373) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. gilvum PYR-GCKMflv_2617-0.082.35% (374) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1595-1e-17681.99% (372) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. marinum MMMAR_3802porB0.089.78% (362) pyruvate:ferredoxin oxidoreductase PorB, beta subunit
M. avium 104MAV_1718orB0.088.98% (363) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. smegmatis MC2 155MSMEG_4645orB1e-17686.43% (339) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. thermoresistible (build 8)TH_0355-0.086.20% (355) PROBABLE OXIDOREDUCTASE (BETA SUBUNIT)
M. ulcerans Agy99MUL_3725porB0.089.23% (362) 2-oxoglutarate ferredoxin oxidoreductase subunit beta
M. vanbaalenii PYR-1Mvan_3964-0.086.03% (358) 2-oxoglutarate ferredoxin oxidoreductase subunit beta

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2617|M.gilvum_PYR-GCK          ---MTTARSEADRASAQLVGNDLGLTPGGLTKTSLVPKTDAPQKGKDFTS
Mvan_3964|M.vanbaalenii_PYR-1       --------------MTDLIGSDLGLTPAGLTKTSLVPTTDEPQKAKDFTT
MSMEG_4645|M.smegmatis_MC2_155      --------------------------------MSLVPTADQPQKAKDFTS
TH_0355|M.thermoresistible__bu      -----------------VIGADLGLIPAGLPKTAGVPTTDQPQKGKDFTS
Rv2454c|M.tuberculosis_H37Rv        MTRSGDEAQLMTGVTGDLAGTELGLTPS-LTKNAGVPTTDQPQKGKDFTS
Mb2481c|M.bovis_AF2122/97           MTRSGDEAQLMTGVTGDLAGTELGLTPS-LTKNAGVPTTDQPQKGKDFTS
MAV_1718|M.avium_104                ----------MTDVVGNLAGKDLGLTAK-LTKNDGVPTTDQPQKAKDFTS
MMAR_3802|M.marinum_M               ----------MTSVIGNLAGTNLGVTPV-FSKNTGVPTTDQPQKGKDFTS
MUL_3725|M.ulcerans_Agy99           ----------MTSVIGNLAGTNLGVTPV-LSKNTGVPTTDQPQKGKDFTS
MAB_1595|M.abscessus_ATCC_1997      -----MTDLLNEASTANGTGSLNGLELG-LTANALVPTTDEEQKAKDFTS
                                                                       **.:*  **.****:

Mflv_2617|M.gilvum_PYR-GCK          DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAFVSGIGCSSRFPYYLE
Mvan_3964|M.vanbaalenii_PYR-1       DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAFVSGIGCSSRFPYYLE
MSMEG_4645|M.smegmatis_MC2_155      DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAFVSGIGCSSRFPYYLE
TH_0355|M.thermoresistible__bu      DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIAFISGIGCSSRFPYYLE
Rv2454c|M.tuberculosis_H37Rv        DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLE
Mb2481c|M.bovis_AF2122/97           DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLE
MAV_1718|M.avium_104                DQEVRWCPGCGDYVILNTIRNFLPDLGLRRENIVFISGIGCSSRFPYYLE
MMAR_3802|M.marinum_M               DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLE
MUL_3725|M.ulcerans_Agy99           DQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLE
MAB_1595|M.abscessus_ATCC_1997      DQEVRWCPGCGDYVILNTIRGFLPELGLKRENIVFISGIGCSSRFPYYLD
                                    ********************.***:***:****.*:*************:

Mflv_2617|M.gilvum_PYR-GCK          TYGFHSIHGRAPTIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
Mvan_3964|M.vanbaalenii_PYR-1       TYGFHSIHGRAPTIATGLALARPDLSVWVVTGDGDALSIGGNHLIHALRR
MSMEG_4645|M.smegmatis_MC2_155      TYGFHSIHGRAPTIATGLALARPDLSVWVVTGDGDSLSIGGNHLIHALRR
TH_0355|M.thermoresistible__bu      TYGFHSIHGRAPTIATGLALARPDLSVWVVTGDGDALSIGGNHLIHALRR
Rv2454c|M.tuberculosis_H37Rv        TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
Mb2481c|M.bovis_AF2122/97           TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
MAV_1718|M.avium_104                TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
MMAR_3802|M.marinum_M               TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRR
MUL_3725|M.ulcerans_Agy99           TYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHAVRR
MAB_1595|M.abscessus_ATCC_1997      TYGMHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHTLRR
                                    ***:********:********* ************:**********::**

Mflv_2617|M.gilvum_PYR-GCK          NINITILLFNNRIYGLTKGQYSPTSETGKVTKSTPMGSLDYPFNPVSLAL
Mvan_3964|M.vanbaalenii_PYR-1       NINVTILLFNNRIYGLTKGQYSPTSETGKVTKSTPMGSLDYPFNPVSLAL
MSMEG_4645|M.smegmatis_MC2_155      NINITILLFNNRIYGLTKGQYSPTSEVGKITKSTPMGSLDYPFNPVSLAL
TH_0355|M.thermoresistible__bu      NMNITILLFNNRIYGLTKGQYSPTSEVGKITKSTPMGSLDHPFNPVSLAL
Rv2454c|M.tuberculosis_H37Rv        NINVTILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDHPFNPVSLAL
Mb2481c|M.bovis_AF2122/97           NINVTILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDHPFNPVSLAL
MAV_1718|M.avium_104                NVNITILLFNNRIYGLTKGQYSPTSEVGKITKSTPMGSLDHPFNPVSLAL
MMAR_3802|M.marinum_M               NVNITILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDTPFNPVSLAL
MUL_3725|M.ulcerans_Agy99           NVNITILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDTPFNPVSLAL
MAB_1595|M.abscessus_ATCC_1997      NVNLTILLFNNRIYGLTKGQYSPTSETGKVTKSTPMGSLDYPFNPVSLAL
                                    *:*:**********************.**:********** *********

Mflv_2617|M.gilvum_PYR-GCK          GAEATFVGRALDSDRKGLTEVLRGAAEHRGAALVEIMQDCPIFNDGSFDA
Mvan_3964|M.vanbaalenii_PYR-1       GAEATFVGRALDSDRKGLSEVLRGAAQHRGAALVEIMQDCPIFNDGSFDA
MSMEG_4645|M.smegmatis_MC2_155      GAEATFVGRALDSDRKGLSEVLRGAAEHRGAALVEIMQDCPIFNDGSFDA
TH_0355|M.thermoresistible__bu      GAEATFVGRALDSDRKGLTEVLRGAAQHRGAALVEIMQDCPIFNDGSFDA
Rv2454c|M.tuberculosis_H37Rv        GAEATFVGRALDSDRNGLTEVLRAAAQHRGAALVEILQDCPIFNDGSFDA
Mb2481c|M.bovis_AF2122/97           GAEATFVGRALDSDRNGLTEVLRAAAQHRGAALVEILQDCPIFNDGSFDA
MAV_1718|M.avium_104                GAEATFVGRALDSDRAGLTEVLQAAAGHRGAAVVEILQDCPIFNDGSFDV
MMAR_3802|M.marinum_M               GAEATFVGRALDSDRAGLSEVLRAATEHRGAALVEILQDCPIFNDGSFDA
MUL_3725|M.ulcerans_Agy99           GAEATFVGRALDSDRAGLSEVLRAATEHRGAALVEILQDCPIFNDGSFDA
MAB_1595|M.abscessus_ATCC_1997      GAEATFVGRALDSDKKGLSEVLRAAAAHRGAALVEILQDCPIFNDGSFDL
                                    **************: **:***:.*: *****:***:************ 

Mflv_2617|M.gilvum_PYR-GCK          LRKEGAEERLINLAHGEPITFGADGEYCVVKSGYGLEVAKTADVSAEEIV
Mvan_3964|M.vanbaalenii_PYR-1       LRKEGAEERLINVTHGEPITFGADGEYCVVKSGYGLEVAKTADVPADEIV
MSMEG_4645|M.smegmatis_MC2_155      LRKEGAEERLINLTHGEPITFGADGEYAVVKSGYGLEIAKTAEVSADDIV
TH_0355|M.thermoresistible__bu      LRKEGSEERLINLKHGEPIVFGANGEYCVIQSGYGLEVAKTADVSAEQIV
Rv2454c|M.tuberculosis_H37Rv        LRKEGAEERVIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDEII
Mb2481c|M.bovis_AF2122/97           LRKEGAEERVIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDEII
MAV_1718|M.avium_104                LRKEGAEERVISVRHGEPIVFGANGEYCVVQSGFGLEVAKTADVSVDEIV
MMAR_3802|M.marinum_M               LRKEGSEERVINVHHGEPIVFGANGEYCVVRSGFGLDVAKTADVAVDEIV
MUL_3725|M.ulcerans_Agy99           LRKEGSEERVINVHHGEPIVFGANGEYCVVRSGFGLDVAKIADVAVDEIV
MAB_1595|M.abscessus_ATCC_1997      LRKEGAEQRVINVRHGEPITFGAEGELCVIRSGFGLEVAKTADVKVEDIV
                                    *****:*:*:*.: *****.***:** .*::**:**::** *:*  ::*:

Mflv_2617|M.gilvum_PYR-GCK          VHDATLQDPAYAFALSRLSEQNLDHMVMGIFRRVNKPTYDDAAREQIASA
Mvan_3964|M.vanbaalenii_PYR-1       VHDATLQDPAYAFALSRLSEQNLDHMVMGIFRQVSKPTYDDAARQQLATA
MSMEG_4645|M.smegmatis_MC2_155      VHDAQIDDPAYAFALSRLSEQNLDHMVMGIFRKVSRPTYDDAARQQVATA
TH_0355|M.thermoresistible__bu      VHDAQIDDPAYAFALSRLSEQNLEHMVMGIFRQVSRPTYDDAARAQIAAA
Rv2454c|M.tuberculosis_H37Rv        VHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVVAA
Mb2481c|M.bovis_AF2122/97           VHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDDAARSQVVAA
MAV_1718|M.avium_104                VHDAHTDNSAYAFALSRLSDQNLEHTVLGIFRDISRPTYDDAARAQVQAA
MMAR_3802|M.marinum_M               VHDAHADDAAYAFALSRLSDQNLEHTVLGIFRSISRPAYDDAARSQISAA
MUL_3725|M.ulcerans_Agy99           VHDAHADDAAYAFALSRLSDQNLEHTVVGIFRSISRPAYDDAARSQISAA
MAB_1595|M.abscessus_ATCC_1997      VHDAHSDDPAYAFALSRLSEQDLEHTVMGVFRSVQRPTYDDLAREQLTAA
                                    ****  ::.**********:*:*:* *:*:** :.:*:*** ** *: :*

Mflv_2617|M.gilvum_PYR-GCK          RSSRAHDTAALQSLLRGKDTWTVD
Mvan_3964|M.vanbaalenii_PYR-1       REAKAHDTAALQSLLRGKDTWTVD
MSMEG_4645|M.smegmatis_MC2_155      IESRPHDTAALQSLLRGKDTWTVD
TH_0355|M.thermoresistible__bu      RADKAHDTQALQALLRGKDTWTVD
Rv2454c|M.tuberculosis_H37Rv        RNAAPSGTAALQSLLHGRDTWTVD
Mb2481c|M.bovis_AF2122/97           RNAAPSGTAALQSLLHGRDTWTVD
MAV_1718|M.avium_104                QSAKAFDSAALQSLLRGRDTWTVD
MMAR_3802|M.marinum_M               RESTPSDSAALQSLLRGRDTWTVS
MUL_3725|M.ulcerans_Agy99           RESTPSDSAALQSLLRGRDTWTVS
MAB_1595|M.abscessus_ATCC_1997      AAAKPSDTAALQALLTGRDTWTVS
                                        . .: ***:** *:*****.